Publications:

---

Pharmacogenomics Guided Prescription Changes Improved Medication Effectiveness in Patients With Mental Health-Related Disability: A Retrospective Cohort Analyses.

Frontiers In Genetics

Ahmed, Sanjida S; Tahir, Ramzan R; Akhtar, Umbreen U; Faiz, Mark M

Publication Date: 2021

Variant appearance in text: rs2072661

PubMed Link: 34413872

Variant Present in the following documents:

• Main text
• fgene-12-644694.pdf

View BVdb publication page

---

Pharmacogenomic landscape of COVID-19 therapies from Indian population genomes.

Pharmacogenomics

Sahana, S S; Sivadas, Ambily A; Mangla, Mohit M; Jain, Abhinav A; Bhoyar, Rahul C RC; Pandhare, Kavita K; Mishra, Anushree A; Sharma, Disha D; Imran, Mohamed M; Senthivel, Vigneshwar V; Divakar, Mohit Kumar MK; Rophina, Mercy M; Jolly, Bani B; Batra, Arushi A; Sharma, Sumit S; Siwach, Sanjay S; Jadhao, Arun G AG; Palande, Nikhil V NV; Jha, Ganga Nath GN; Ashrafi, Nishat N; Mishra, Prashant Kumar PK; Vidhya, A K AK; Jain, Suman S; Dash, Debasis D; Kumar, Nachimuthu Senthil NS; Vanlallawma, Andrew A; Sarma, Ranjan Jyoti RJ; Chhakchhuak, Lalchhandama L; Kalyanaraman, Shantaraman S; Mahadevan, Radha R; Kandasamy, Sunitha S; Devi, Pabitha P; Rajagopal, Raskin Erusan RE; Ramya, J Ezhil JE; Devi, P Nirmala PN; Bajaj, Anjali A; Gupta, Vishu V; Mathew, Samatha S; Goswami, Sangam S; Prakash, Savinitha S; Joshi, Kandarp K; Kumla, Meya M; Sreedevi, S S; Gajjar, Devarshi D; Soraisham, Ronibala R; Yadav, Rohit R; Devi, Yumnam Silla YS; Gupta, Aayush A; Mukerji, Mitali M; Ramalingam, Sivaprakash S; Binukumar, B K BK; Sivasubbu, Sridhar S; Scaria, Vinod V

Publication Date: 2021-07

Variant appearance in text: rs2072661

PubMed Link: 34142560

Variant Present in the following documents:

• pgs-2021-0028.pdf

View BVdb publication page

---

Pharmacogenetic study of seven polymorphisms in three nicotinic acetylcholine receptor subunits in smoking-cessation therapies.

Scientific Reports

Pintarelli, Giulia G; Galvan, Antonella A; Pozzi, Paolo P; Noci, Sara S; Pasetti, Giovanna G; Sala, Francesca F; Pastorino, Ugo U; Boffi, Roberto R; Colombo, Francesca F

Publication Date: 2017-12-01

Variant appearance in text: rs2072661

PubMed Link: 29196725

Variant Present in the following documents:

• Main text
• 41598_2017_Article_16946.pdf

View BVdb publication page

---

Pharmacogenetic Optimization of Smoking Cessation Treatment.

Trends In Pharmacological Sciences

Chenoweth, Meghan J MJ; Tyndale, Rachel F RF

Publication Date: 2017-01

Variant appearance in text: rs2072661

PubMed Link: 27712845

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Nicotinic receptor contributions to smoking: insights from human studies and animal models.

Current Addiction Reports

Brunzell, Darlene H DH; Stafford, Alexandra M AM; Dixon, Claire I CI

Publication Date: 2015-03

Variant appearance in text: rs2072661

PubMed Link: 26301171

Variant Present in the following documents:

• Main text

View BVdb publication page

---

The DYX2 locus and neurochemical signaling genes contribute to speech sound disorder and related neurocognitive domains.

Genes, Brain, And Behavior

Eicher, J D JD; Stein, C M CM; Deng, F F; Ciesla, A A AA; Powers, N R NR; Boada, R R; Smith, S D SD; Pennington, B F BF; Iyengar, S K SK; Lewis, B A BA; Gruen, J R JR

Publication Date: 2015-04

Variant appearance in text: rs2072661

PubMed Link: 25778907

Variant Present in the following documents:

• Main text

View BVdb publication page

---

CHRNA4 rs1044396 is associated with smoking cessation in varenicline therapy.

Frontiers In Genetics

Rocha Santos, Juliana J; Tomaz, Paulo R X PR; Issa, Jaqueline S JS; Abe, Tânia O TO; Krieger, José E JE; Pereira, Alexandre C AC; Santos, Paulo C J L PC

Publication Date: 2015

Variant appearance in text: rs2072661

PubMed Link: 25774163

Variant Present in the following documents:

• Main text
• fgene-06-00046.pdf

View BVdb publication page

---

Joint association of nicotinic acetylcholine receptor variants with abdominal obesity in American Indians: the Strong Heart Family Study.

Plos One

Zhu, Yun Y; Yang, Jingyun J; Yeh, Fawn F; Cole, Shelley A SA; Haack, Karin K; Lee, Elisa T ET; Howard, Barbara V BV; Zhao, Jinying J

Publication Date: 2014

Variant appearance in text: rs2072661

PubMed Link: 25036316

Variant Present in the following documents:

• Main text
• pone.0102220.pdf

View BVdb publication page

---

Nicotine dependence as a moderator of genetic influences on smoking cessation treatment outcome.

Drug And Alcohol Dependence

Leventhal, Adam M AM; Lee, Wonho W; Bergen, Andrew W AW; Swan, Gary E GE; Tyndale, Rachel F RF; Lerman, Caryn C; Conti, David V DV

Publication Date: 2014-05-01

Variant appearance in text: rs2072661

PubMed Link: 24667010

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Genetic variants in nicotinic acetylcholine receptor genes jointly contribute to kidney function in American Indians: the Strong Heart Family Study.

Journal Of Hypertension

Zhu, Yun Y; Yang, Jingyun J; Li, Shengxu S; Cole, Shelley A SA; Haack, Karin K; Umans, Jason G JG; Franceschini, Nora N; Howard, Barbara V BV; Lee, Elisa T ET; Zhao, Jinying J

Publication Date: 2014-05

Variant appearance in text: rs2072661

PubMed Link: 24569419

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Finding genomic function for genetic associations in nicotine addiction research: the ENCODE project's role in future pharmacogenomic analysis.

Pharmacology, Biochemistry, And Behavior

Vandenbergh, David J DJ; Schlomer, Gabriel L GL

Publication Date: 2014-08

Variant appearance in text: rs2072661

PubMed Link: 24486638

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Association of the CHRNA4 neuronal nicotinic receptor subunit gene with frequency of binge drinking in young adults.

Alcoholism, Clinical And Experimental Research

Coon, Hilary H; Piasecki, Thomas M TM; Cook, Edwin H EH; Dunn, Diane D; Mermelstein, Robin J RJ; Weiss, Robert B RB; Cannon, Dale S DS

Publication Date: 2014-04

Variant appearance in text: rs2072661

PubMed Link: 24428733

Variant Present in the following documents:

• Main text
• acer-38-930.pdf

View BVdb publication page

---

The CHRNA3 rs578776 Variant is Associated with an Intrinsic Reward Sensitivity Deficit in Smokers.

Frontiers In Psychiatry

Robinson, Jason D JD; Versace, Francesco F; Lam, Cho Y CY; Minnix, Jennifer A JA; Engelmann, Jeffrey M JM; Cui, Yong Y; Karam-Hage, Maher M; Shete, Sanjay S SS; Tomlinson, Gail E GE; Chen, Tina T-L TT; Wetter, David W DW; Green, Charles E CE; Cinciripini, Paul M PM

Publication Date: 2013

Variant appearance in text: rs2072661

PubMed Link: 24065931

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Effect of neuronal nicotinic acetylcholine receptor genes (CHRN) on longitudinal cigarettes per day in adolescents and young adults.

Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco

Cannon, Dale S DS; Mermelstein, Robin J RJ; Hedeker, Donald D; Coon, Hilary H; Cook, Edwin H EH; McMahon, William M WM; Hamil, Cindy C; Dunn, Diane D; Weiss, Robert B RB

Publication Date: 2014-02

Variant appearance in text: rs2072661

PubMed Link: 23943838

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Integrative variable selection via Bayesian model uncertainty.

Statistics In Medicine

Quintana, M A MA; Conti, D V DV

Publication Date: 2013-12-10

Variant appearance in text: rs2072661

PubMed Link: 23824835

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Associations of prenatal nicotine exposure and the dopamine related genes ANKK1 and DRD2 to verbal language.

Plos One

Eicher, John D JD; Powers, Natalie R NR; Cho, Kelly K; Miller, Laura L LL; Mueller, Kathryn L KL; Ring, Susan M SM; Tomblin, J Bruce JB; Gruen, Jeffrey R JR

Publication Date: 2013

Variant appearance in text: rs2072661

PubMed Link: 23691092

Variant Present in the following documents:

• Main text
• pone.0063762.pdf

View BVdb publication page

---

Nominal association with CHRNA4 variants and nicotine dependence.

Genes, Brain, And Behavior

Kamens, H M HM; Corley, R P RP; McQueen, M B MB; Stallings, M C MC; Hopfer, C J CJ; Crowley, T J TJ; Brown, S A SA; Hewitt, J K JK; Ehringer, M A MA

Publication Date: 2013-04

Variant appearance in text: rs2072661

PubMed Link: 23350800

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Joint associations of 61 genetic variants in the nicotinic acetylcholine receptor genes with subclinical atherosclerosis in American Indians: a gene-family analysis.

Circulation. Cardiovascular Genetics

Yang, Jingyun J; Zhu, Yun Y; Lee, Elisa T ET; Zhang, Ying Y; Cole, Shelley A SA; Haack, Karin K; Best, Lyle G LG; Devereux, Richard B RB; Roman, Mary J MJ; Howard, Barbara V BV; Zhao, Jinying J

Publication Date: 2013-02

Variant appearance in text: rs2072661

PubMed Link: 23264444

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Nicotinic acetylcholine receptor variation and response to smoking cessation therapies.

Pharmacogenetics And Genomics

Bergen, Andrew W AW; Javitz, Harold S HS; Krasnow, Ruth R; Nishita, Denise D; Michel, Martha M; Conti, David V DV; Liu, Jinghua J; Lee, Won W; Edlund, Christopher K CK; Hall, Sharon S; Kwok, Pui-Yan PY; Benowitz, Neal L NL; Baker, Timothy B TB; Tyndale, Rachel F RF; Lerman, Caryn C; Swan, Gary E GE

Publication Date: 2013-02

Variant appearance in text: rs2072661

PubMed Link: 23249876

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes.

Human Genetics

Gold, Allison B AB; Lerman, Caryn C

Publication Date: 2012-01-31

Variant appearance in text: rs2072661

PubMed Link: 22290489

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Biomarkers to optimize the treatment of nicotine dependence.

Biomarkers In Medicine

Schnoll, Robert A RA; Leone, Frank T FT

Publication Date: 2011-12

Variant appearance in text: rs2072661

PubMed Link: 22103610

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Pharmacogenetics: a tool for identifying genetic factors in drug dependence and response to treatment.

Addiction Science & Clinical Practice

Mroziewicz, Margaret M; Tyndale, Rachel F RF

Publication Date: 2010-12

Variant appearance in text: rs2072661

PubMed Link: 22002450

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Gender-stratified gene and gene-treatment interactions in smoking cessation.

The Pharmacogenomics Journal

Lee, W W; Bergen, A W AW; Swan, G E GE; Li, D D; Liu, J J; Thomas, P P; Tyndale, R F RF; Benowitz, N L NL; Lerman, C C; Conti, D V DV

Publication Date: 2012-12

Variant appearance in text: rs2072661

PubMed Link: 21808284

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Varenicline for smoking cessation: nausea severity and variation in nicotinic receptor genes.

The Pharmacogenomics Journal

Swan, G E GE; Javitz, H S HS; Jack, L M LM; Wessel, J J; Michel, M M; Hinds, D A DA; Stokowksi, R P RP; McClure, J B JB; Catz, S L SL; Richards, J J; Zbikowski, S M SM; Deprey, M M; McAfee, T T; Conti, D V DV; Bergen, A W AW

Publication Date: 2012-08

Variant appearance in text: rs2072661

PubMed Link: 21606948

Variant Present in the following documents:

• Main text
• nihms289948.pdf

View BVdb publication page

---

Breaking barriers in the genomics and pharmacogenetics of drug addiction.

Clinical Pharmacology And Therapeutics

Ho, M K MK; Goldman, D D; Heinz, A A; Kaprio, J J; Kreek, M J MJ; Li, M D MD; Munafò, M R MR; Tyndale, R F RF

Publication Date: 2010-12

Variant appearance in text: rs2072661

PubMed Link: 20981002

Variant Present in the following documents:

• Main text

View BVdb publication page

---

CHRNB2 promoter region: association with subjective effects to nicotine and gene expression differences.

Genes, Brain, And Behavior

Hoft, N R NR; Stitzel, J A JA; Hutchison, K E KE; Ehringer, M A MA

Publication Date: 2011-03

Variant appearance in text: rs2072661

PubMed Link: 20854418

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Resequencing of nicotinic acetylcholine receptor genes and association of common and rare variants with the Fagerström test for nicotine dependence.

Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology

Wessel, Jennifer J; McDonald, Sarah M SM; Hinds, David A DA; Stokowski, Renee P RP; Javitz, Harold S HS; Kennemer, Michael M; Krasnow, Ruth R; Dirks, William W; Hardin, Jill J; Pitts, Steven J SJ; Michel, Martha M; Jack, Lisa L; Ballinger, Dennis G DG; McClure, Jennifer B JB; Swan, Gary E GE; Bergen, Andrew W AW

Publication Date: 2010-11

Variant appearance in text: rs2072661

PubMed Link: 20736995

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans.

American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics

Li, Ming D MD; Xu, Qing Q; Lou, Xiang-Yang XY; Payne, Thomas J TJ; Niu, Tianhua T; Ma, Jennie Z JZ

Publication Date: 2010-04-05

Variant appearance in text: rs2072661

PubMed Link: 19859904

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Nicotinic acetylcholine receptor beta2 subunit (CHRNB2) gene and short-term ability to quit smoking in response to nicotine patch.

Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology

Perkins, Kenneth A KA; Lerman, Caryn C; Mercincavage, Melissa M; Fonte, Carolyn A CA; Briski, Jessica L JL

Publication Date: 2009-10

Variant appearance in text: rs2072661

PubMed Link: 19755656

Variant Present in the following documents:

• Main text

View BVdb publication page

---

New insights into the genetics of addiction.

Nature Reviews. Genetics

Li, Ming D MD; Burmeister, Margit M

Publication Date: 2009-04

Variant appearance in text: rs2072661

PubMed Link: 19238175

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation.

Human Molecular Genetics

Conti, David V DV; Lee, Won W; Li, Dalin D; Liu, Jinghua J; Van Den Berg, David D; Thomas, Paul D PD; Bergen, Andrew W AW; Swan, Gary E GE; Tyndale, Rachel F RF; Benowitz, Neal L NL; Lerman, Caryn C; ,

Publication Date: 2008-09-15

Variant appearance in text: rs2072661

PubMed Link: 18593715

Variant Present in the following documents:

• Main text
• ddn181.pdf

View BVdb publication page

---

Gene-gene interactions among CHRNA4, CHRNB2, BDNF, and NTRK2 in nicotine dependence.

Biological Psychiatry

Li, Ming D MD; Lou, Xiang-Yang XY; Chen, Guobo G; Ma, Jennie Z JZ; Elston, Robert C RC

Publication Date: 2008-12-01

Variant appearance in text: rs2072661

PubMed Link: 18534558

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Identification of pharmacogenetic markers in smoking cessation therapy.

American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics

Heitjan, Daniel F DF; Guo, Mengye M; Ray, Riju R; Wileyto, E Paul EP; Epstein, Leonard H LH; Lerman, Caryn C

Publication Date: 2008-09-05

Variant appearance in text: rs2072661

PubMed Link: 18165968

Variant Present in the following documents:

• Main text

View BVdb publication page

---

A generalized combinatorial approach for detecting gene-by-gene and gene-by-environment interactions with application to nicotine dependence.

American Journal Of Human Genetics

Lou, Xiang-Yang XY; Chen, Guo-Bo GB; Yan, Lei L; Ma, Jennie Z JZ; Zhu, Jun J; Elston, Robert C RC; Li, Ming D MD

Publication Date: 2007-06

Variant appearance in text: rs2072661

PubMed Link: 17503330

Variant Present in the following documents:

• Main text

View BVdb publication page

---

A common haplotype of the nicotine acetylcholine receptor alpha 4 subunit gene is associated with vulnerability to nicotine addiction in men.

American Journal Of Human Genetics

Feng, Yan Y; Niu, Tianhua T; Xing, Houxun H; Xu, Xin X; Chen, Changzhong C; Peng, Shaojie S; Wang, Lihua L; Laird, Nan N; Xu, Xiping X

Publication Date: 2004-07

Variant appearance in text: rs2072661

PubMed Link: 15154117

Variant Present in the following documents:

• Main text

View BVdb publication page

---