Nontrivial Replication of Loci Detected by Multi-Trait Methods.
Frontiers In Genetics
Ning, Zheng Z; Tsepilov, Yakov A YA; Sharapov, Sodbo Zh SZ; Wang, Zhipeng Z; Grishenko, Alexander K AK; Feng, Xiao X; Shirali, Masoud M; Joshi, Peter K PK; Wilson, James F JF; Pawitan, Yudi Y; Haley, Chris S CS; Aulchenko, Yurii S YS; Shen, Xia X
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.
Nature Genetics
Justice, Anne E AE; Karaderi, Tugce T; Highland, Heather M HM; Young, Kristin L KL; Graff, Mariaelisa M; Lu, Yingchang Y; Turcot, Valérie V; Auer, Paul L PL; Fine, Rebecca S RS; Guo, Xiuqing X; Schurmann, Claudia C; Lempradl, Adelheid A; Marouli, Eirini E; Mahajan, Anubha A; Winkler, Thomas W TW; Locke, Adam E AE; Medina-Gomez, Carolina C; Esko, Tõnu T; Vedantam, Sailaja S; Giri, Ayush A; Lo, Ken Sin KS; Alfred, Tamuno T; Mudgal, Poorva P; Ng, Maggie C Y MCY; Heard-Costa, Nancy L NL; Feitosa, Mary F MF; Manning, Alisa K AK; Willems, Sara M SM; Sivapalaratnam, Suthesh S; Abecasis, Goncalo G; Alam, Dewan S DS; Allison, Matthew M; Amouyel, Philippe P; Arzumanyan, Zorayr Z; Balkau, Beverley B; Bastarache, Lisa L; Bergmann, Sven S; Bielak, Lawrence F LF; Blüher, Matthias M; Boehnke, Michael M; Boeing, Heiner H; Boerwinkle, Eric E; Böger, Carsten A CA; Bork-Jensen, Jette J; Bottinger, Erwin P EP; Bowden, Donald W DW; Brandslund, Ivan I; Broer, Linda L; Burt, Amber A AA; Butterworth, Adam S AS; 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The association between weight at birth and breast cancer risk revisited using Mendelian randomisation.
European Journal Of Epidemiology
Kar, Siddhartha P SP; Andrulis, Irene L IL; Brenner, Hermann H; Burgess, Stephen S; Chang-Claude, Jenny J; Considine, Daniel D; Dörk, Thilo T; Evans, Dafydd Gareth R DGR; Gago-Domínguez, Manuela M; Giles, Graham G GG; Hartman, Mikael M; Huo, Dezheng D; Kaaks, Rudolf R; Li, Jingmei J; Lophatananon, Artitaya A; Margolin, Sara S; Milne, Roger L RL; Muir, Kenneth R KR; Olsson, Håkan H; Punie, Kevin K; Radice, Paolo P; Simard, Jacques J; Tamimi, Rulla M RM; Van Nieuwenhuysen, Els E; Wendt, Camilla C; Zheng, Wei W; Pharoah, Paul D P PDP
Genome-wide DNA promoter methylation and transcriptome analysis in human adipose tissue unravels novel candidate genes for obesity.
Molecular Metabolism
Keller, Maria M; Hopp, Lydia L; Liu, Xuanshi X; Wohland, Tobias T; Rohde, Kerstin K; Cancello, Raffaella R; Klös, Matthias M; Bacos, Karl K; Kern, Matthias M; Eichelmann, Fabian F; Dietrich, Arne A; Schön, Michael R MR; Gärtner, Daniel D; Lohmann, Tobias T; Dreßler, Miriam M; Stumvoll, Michael M; Kovacs, Peter P; DiBlasio, Anna-Maria AM; Ling, Charlotte C; Binder, Hans H; Blüher, Matthias M; Böttcher, Yvonne Y
Investigation of Genetic Variation Underlying Central Obesity amongst South Asians.
Plos One
Scott, William R WR; Zhang, Weihua W; Loh, Marie M; Tan, Sian-Tsung ST; Lehne, Benjamin B; Afzal, Uzma U; Peralta, Juan J; Saxena, Richa R; Ralhan, Sarju S; Wander, Gurpreet S GS; Bozaoglu, Kiymet K; Sanghera, Dharambir K DK; Elliott, Paul P; Scott, James J; Chambers, John C JC; Kooner, Jaspal S JS
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.
Nature Communications
Kilpeläinen, Tuomas O TO; Carli, Jayne F Martin JF; Skowronski, Alicja A AA; Sun, Qi Q; Kriebel, Jennifer J; Feitosa, Mary F MF; Hedman, Åsa K ÅK; Drong, Alexander W AW; Hayes, James E JE; Zhao, Jinghua J; Pers, Tune H TH; Schick, Ursula U; Grarup, Niels N; Kutalik, Zoltán Z; Trompet, Stella S; Mangino, Massimo M; Kristiansson, Kati K; Beekman, Marian M; Lyytikäinen, Leo-Pekka LP; Eriksson, Joel J; Henneman, Peter P; Lahti, Jari J; Tanaka, Toshiko T; Luan, Jian'an J; Del Greco M, Fabiola F; Pasko, Dorota D; Renström, Frida F; Willems, Sara M SM; Mahajan, Anubha A; Rose, Lynda M LM; Guo, Xiuqing X; Liu, Yongmei Y; Kleber, Marcus E ME; Pérusse, Louis L; Gaunt, Tom T; Ahluwalia, Tarunveer S TS; Ju Sung, Yun Y; Ramos, Yolande F YF; Amin, Najaf N; Amuzu, Antoinette A; Barroso, Inês I; Bellis, Claire C; Blangero, John J; Buckley, Brendan M BM; Böhringer, Stefan S; I Chen, Yii-Der YD; de Craen, Anton J N AJ; Crosslin, David R DR; Dale, Caroline E CE; Dastani, Zari Z; Day, Felix R FR; Deelen, Joris J; Delgado, Graciela E GE; Demirkan, Ayse A; Finucane, Francis M FM; Ford, Ian I; Garcia, Melissa E ME; Gieger, Christian C; Gustafsson, Stefan S; Hallmans, Göran G; Hankinson, Susan E SE; Havulinna, Aki S AS; Herder, Christian C; Hernandez, Dena D; Hicks, Andrew A AA; Hunter, David J DJ; Illig, Thomas T; Ingelsson, Erik E; Ioan-Facsinay, Andreea A; Jansson, John-Olov JO; Jenny, Nancy S NS; Jørgensen, Marit E ME; Jørgensen, Torben T; Karlsson, Magnus M; Koenig, Wolfgang W; Kraft, Peter P; Kwekkeboom, Joanneke J; Laatikainen, Tiina T; Ladwig, Karl-Heinz KH; LeDuc, Charles A CA; Lowe, Gordon G; Lu, Yingchang Y; Marques-Vidal, Pedro P; Meisinger, Christa C; Menni, Cristina C; Morris, Andrew P AP; Myers, Richard H RH; Männistö, Satu S; Nalls, Mike A MA; Paternoster, Lavinia L; Peters, Annette A; Pradhan, Aruna D AD; Rankinen, Tuomo T; Rasmussen-Torvik, Laura J LJ; Rathmann, Wolfgang W; Rice, Treva K TK; Brent Richards, J J; Ridker, Paul M PM; Sattar, Naveed N; Savage, David B DB; Söderberg, Stefan S; Timpson, Nicholas J NJ; Vandenput, Liesbeth L; van Heemst, Diana D; Uh, Hae-Won HW; Vohl, Marie-Claude MC; Walker, Mark M; Wichmann, Heinz-Erich HE; Widén, Elisabeth E; Wood, Andrew R AR; Yao, Jie J; Zeller, Tanja T; Zhang, Yiying Y; Meulenbelt, Ingrid I; Kloppenburg, Margreet M; Astrup, Arne A; Sørensen, Thorkild I A TI; Sarzynski, Mark A MA; Rao, D C DC; Jousilahti, Pekka P; Vartiainen, Erkki E; Hofman, Albert A; Rivadeneira, Fernando F; Uitterlinden, André G AG; Kajantie, Eero E; Osmond, Clive C; Palotie, Aarno A; Eriksson, Johan G JG; Heliövaara, Markku M; Knekt, Paul B PB; Koskinen, Seppo S; Jula, Antti A; Perola, Markus M; Huupponen, Risto K RK; Viikari, Jorma S JS; Kähönen, Mika M; Lehtimäki, Terho T; Raitakari, Olli T OT; Mellström, Dan D; Lorentzon, Mattias M; Casas, Juan P JP; Bandinelli, Stefanie S; März, Winfried W; Isaacs, Aaron A; van Dijk, Ko W KW; van Duijn, Cornelia M CM; Harris, Tamara B TB; Bouchard, Claude C; Allison, Matthew A MA; Chasman, Daniel I DI; Ohlsson, Claes C; Lind, Lars L; Scott, Robert A RA; Langenberg, Claudia C; Wareham, Nicholas J NJ; Ferrucci, Luigi L; Frayling, Timothy M TM; Pramstaller, Peter P PP; Borecki, Ingrid B IB; Waterworth, Dawn M DM; Bergmann, Sven S; Waeber, Gérard G; Vollenweider, Peter P; Vestergaard, Henrik H; Hansen, Torben T; Pedersen, Oluf O; Hu, Frank B FB; Eline Slagboom, P P; Grallert, Harald H; Spector, Tim D TD; Jukema, J W JW; Klein, Robert J RJ; Schadt, Erik E EE; Franks, Paul W PW; Lindgren, Cecilia M CM; Leibel, Rudolph L RL; Loos, Ruth J F RJ
New genetic loci link adipose and insulin biology to body fat distribution.
Nature
Shungin, Dmitry D; Winkler, Thomas W TW; Croteau-Chonka, Damien C DC; Ferreira, Teresa T; Locke, Adam E AE; Mägi, Reedik R; Strawbridge, Rona J RJ; Pers, Tune H TH; Fischer, Krista K; Justice, Anne E AE; Workalemahu, Tsegaselassie T; Wu, Joseph M W JMW; Buchkovich, Martin L ML; Heard-Costa, Nancy L NL; Roman, Tamara S TS; Drong, Alexander W AW; Song, Ci C; Gustafsson, Stefan S; Day, Felix R FR; Esko, Tonu T; Fall, Tove T; Kutalik, Zoltán Z; Luan, Jian'an J; Randall, Joshua C JC; Scherag, André A; Vedantam, Sailaja S; Wood, Andrew R AR; Chen, Jin J; Fehrmann, Rudolf R; Karjalainen, Juha J; Kahali, Bratati B; Liu, Ching-Ti CT; Schmidt, Ellen M EM; Absher, Devin D; Amin, Najaf N; Anderson, Denise D; Beekman, Marian M; Bragg-Gresham, Jennifer L JL; Buyske, Steven S; Demirkan, Ayse A; Ehret, Georg B GB; Feitosa, Mary F MF; Goel, Anuj A; Jackson, Anne U AU; Johnson, Toby T; Kleber, Marcus E ME; Kristiansson, Kati K; Mangino, Massimo M; Leach, Irene Mateo IM; Medina-Gomez, Carolina C; Palmer, Cameron D CD; 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A novel common variant in DCST2 is associated with length in early life and height in adulthood.
Human Molecular Genetics
van der Valk, Ralf J P RJ; Kreiner-Møller, Eskil E; Kooijman, Marjolein N MN; Guxens, Mònica M; Stergiakouli, Evangelia E; Sääf, Annika A; Bradfield, Jonathan P JP; Geller, Frank F; Hayes, M Geoffrey MG; Cousminer, Diana L DL; Körner, Antje A; Thiering, Elisabeth E; Curtin, John A JA; Myhre, Ronny R; Huikari, Ville V; Joro, Raimo R; Kerkhof, Marjan M; Warrington, Nicole M NM; Pitkänen, Niina N; Ntalla, Ioanna I; Horikoshi, Momoko M; Veijola, Riitta R; Freathy, Rachel M RM; Teo, Yik-Ying YY; Barton, Sheila J SJ; Evans, David M DM; Kemp, John P JP; St Pourcain, Beate B; Ring, Susan M SM; Davey Smith, George G; Bergström, Anna A; Kull, Inger I; Hakonarson, Hakon H; Mentch, Frank D FD; Bisgaard, Hans H; Chawes, Bo B; Stokholm, Jakob J; Waage, Johannes J; Eriksen, Patrick P; Sevelsted, Astrid A; Melbye, Mads M; , ; van Duijn, Cornelia M CM; Medina-Gomez, Carolina C; Hofman, Albert A; de Jongste, Johan C JC; Taal, H Rob HR; Uitterlinden, André G AG; , ; Armstrong, Loren L LL; Eriksson, Johan J; Palotie, Aarno A; Bustamante, Mariona M; Estivill, Xavier X; Gonzalez, Juan R JR; Llop, Sabrina S; Kiess, Wieland W; Mahajan, Anubha A; Flexeder, Claudia C; Tiesler, Carla M T CM; Murray, Clare S CS; Simpson, Angela A; Magnus, Per P; Sengpiel, Verena V; Hartikainen, Anna-Liisa AL; Keinanen-Kiukaanniemi, Sirkka S; Lewin, Alexandra A; Da Silva Couto Alves, Alexessander A; Blakemore, Alexandra I AI; Buxton, Jessica L JL; Kaakinen, Marika M; Rodriguez, Alina A; Sebert, Sylvain S; Vaarasmaki, Marja M; Lakka, Timo T; Lindi, Virpi V; Gehring, Ulrike U; Postma, Dirkje S DS; Ang, Wei W; Newnham, John P JP; Lyytikäinen, Leo-Pekka LP; Pahkala, Katja K; Raitakari, Olli T OT; Panoutsopoulou, Kalliope K; Zeggini, Eleftheria E; Boomsma, Dorret I DI; Groen-Blokhuis, Maria M; Ilonen, Jorma J; Franke, Lude L; Hirschhorn, Joel N JN; Pers, Tune H TH; Liang, Liming L; Huang, Jinyan J; Hocher, Berthold B; Knip, Mikael M; Saw, Seang-Mei SM; Holloway, John W JW; Melén, Erik E; Grant, Struan F A SF; Feenstra, Bjarke B; Lowe, William L WL; Widén, Elisabeth E; Sergeyev, Elena E; Grallert, Harald H; Custovic, Adnan A; Jacobsson, Bo B; Jarvelin, Marjo-Riitta MR; Atalay, Mustafa M; Koppelman, Gerard H GH; Pennell, Craig E CE; Niinikoski, Harri H; Dedoussis, George V GV; Mccarthy, Mark I MI; Frayling, Timothy M TM; Sunyer, Jordi J; Timpson, Nicholas J NJ; Rivadeneira, Fernando F; Bønnelykke, Klaus K; Jaddoe, Vincent W V VW; ,
Intracranial aneurysm risk locus 5q23.2 is associated with elevated systolic blood pressure.
Plos Genetics
Gaál, Emília Ilona EI; Salo, Perttu P; Kristiansson, Kati K; Rehnström, Karola K; Kettunen, Johannes J; Sarin, Antti-Pekka AP; Niemelä, Mika M; Jula, Antti A; Raitakari, Olli T OT; Lehtimäki, Terho T; Eriksson, Johan G JG; Widen, Elisabeth E; Günel, Murat M; Kurki, Mitja M; von und Zu Fraunberg, Mikael M; Jääskeläinen, Juha E JE; Hernesniemi, Juha J; Järvelin, Marjo-Riitta MR; Pouta, Anneli A; , ; Newton-Cheh, Christopher C; Salomaa, Veikko V; Palotie, Aarno A; Perola, Markus M
Common variant near the endothelin receptor type A (EDNRA) gene is associated with intracranial aneurysm risk.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Yasuno, Katsuhito K; Bakırcıoğlu, Mehmet M; Low, Siew-Kee SK; Bilgüvar, Kaya K; Gaál, Emília E; Ruigrok, Ynte M YM; Niemelä, Mika M; Hata, Akira A; Bijlenga, Philippe P; Kasuya, Hidetoshi H; Jääskeläinen, Juha E JE; Krex, Dietmar D; Auburger, Georg G; Simon, Matthias M; Krischek, Boris B; Ozturk, Ali K AK; Mane, Shrikant S; Rinkel, Gabriel J E GJ; Steinmetz, Helmuth H; Hernesniemi, Juha J; Schaller, Karl K; Zembutsu, Hitoshi H; Inoue, Ituro I; Palotie, Aarno A; Cambien, François F; Nakamura, Yusuke Y; Lifton, Richard P RP; Günel, Murat M