The longitudinal loss of islet autoantibody responses from diagnosis of type 1 diabetes occurs progressively over follow-up and is determined by low autoantibody titres, early-onset, and genetic variants.
Clinical And Experimental Immunology
Williams, C L CL; Fareed, R R; Mortimer, G L M GLM; Aitken, R J RJ; Wilson, I V IV; George, G G; Gillespie, K M KM; Williams, A J K AJK; , ; Long, A E AE
Natural Killer cells demonstrate distinct eQTL and transcriptome-wide disease associations, highlighting their role in autoimmunity.
Nature Communications
Gilchrist, James J JJ; Makino, Seiko S; Naranbhai, Vivek V; Sharma, Piyush K PK; Koturan, Surya S; Tong, Orion O; Taylor, Chelsea A CA; Watson, Robert A RA; de Los Aires, Alba Verge AV; Cooper, Rosalin R; Lau, Evelyn E; Danielli, Sara S; Hameiri-Bowen, Dan D; Lee, Wanseon W; Ng, Esther E; Whalley, Justin J; Knight, Julian C JC; Fairfax, Benjamin P BP
Characterization of Rheumatoid Arthritis Risk-Associated SNPs and Identification of Novel Therapeutic Sites Using an In-Silico Approach.
Biology
Akhtar, Mehran M; Ali, Yasir Y; Islam, Zia-Ul ZU; Arshad, Maria M; Rauf, Mamoona M; Ali, Muhammad M; Maodaa, Saleh N SN; Al-Farraj, Saleh A SA; El-Serehy, Hamed A HA; Jalil, Fazal F
Two genetic variants explain the association of European ancestry with multiple sclerosis risk in African-Americans.
Scientific Reports
Nakatsuka, Nathan N; Patterson, Nick N; Patsopoulos, Nikolaos A NA; Altemose, Nicolas N; Tandon, Arti A; Beecham, Ashley H AH; McCauley, Jacob L JL; Isobe, Noriko N; Hauser, Stephen S; De Jager, Philip L PL; Hafler, David A DA; Oksenberg, Jorge R JR; Reich, David D
Dysregulated Antibody, Natural Killer Cell and Immune Mediator Profiles in Autoimmune Thyroid Diseases.
Cells
Martin, Tiphaine C TC; Ilieva, Kristina M KM; Visconti, Alessia A; Beaumont, Michelle M; Kiddle, Steven J SJ; Dobson, Richard J B RJB; Mangino, Massimo M; Lim, Ee Mun EM; Pezer, Marija M; Steves, Claire J CJ; Bell, Jordana T JT; Wilson, Scott G SG; Lauc, Gordan G; Roederer, Mario M; Walsh, John P JP; Spector, Tim D TD; Karagiannis, Sophia N SN
Fc receptor-like 3 (-169T>C) polymorphism increases the risk of tendinopathy in volleyball athletes: a case control study.
Bmc Medical Genetics
Salles, José Inácio JI; Lopes, Lucas Rafael LR; Duarte, Maria Eugenia Leite MEL; Morrissey, Dylan D; Martins, Marilena Bezerra MB; Machado, Daniel Escorsim DE; Guimarães, João Antonio Matheus JAM; Perini, Jamila Alessandra JA
Pooled genome wide association detects association upstream of FCRL3 with Graves' disease.
Bmc Genomics
Khong, Jwu Jin JJ; Burdon, Kathryn P KP; Lu, Yi Y; Laurie, Kate K; Leonardos, Lefta L; Baird, Paul N PN; Sahebjada, Srujana S; Walsh, John P JP; Gajdatsy, Adam A; Ebeling, Peter R PR; Hamblin, Peter Shane PS; Wong, Rosemary R; Forehan, Simon P SP; Fourlanos, Spiros S; Roberts, Anthony P AP; Doogue, Matthew M; Selva, Dinesh D; Montgomery, Grant W GW; Macgregor, Stuart S; Craig, Jamie E JE
Wang, Yunpeng Y; Bos, Steffan D SD; Harbo, Hanne F HF; Thompson, Wesley K WK; Schork, Andrew J AJ; Bettella, Francesco F; Witoelar, Aree A; Lie, Benedicte A BA; Li, Wen W; McEvoy, Linda K LK; Djurovic, Srdjan S; Desikan, Rahul S RS; Dale, Anders M AM; Andreassen, Ole A OA
Novel Association Between Immune-Mediated Susceptibility Loci and Persistent Autoantibody Positivity in Type 1 Diabetes.
Diabetes
Brorsson, Caroline A CA; Onengut, Suna S; Chen, Wei-Min WM; Wenzlau, Janet J; Yu, Liping L; Baker, Peter P; Williams, Alistair J K AJ; Bingley, Polly J PJ; Hutton, John C JC; Eisenbarth, George S GS; Concannon, Patrick P; Rich, Stephen S SS; Pociot, Flemming F; ,
A genetic study on C5-TRAF1 and progression of joint damage in rheumatoid arthritis.
Arthritis Research & Therapy
van Steenbergen, Hanna W HW; Rodríguez-Rodríguez, Luis L; Berglin, Ewa E; Zhernakova, Alexandra A; Knevel, Rachel R; Ivorra-Cortés, Jose J; Huizinga, Tom W J TW; Fernández-Gutiérrez, Benjamin B; Gregersen, Peter K PK; Rantapää-Dahlqvist, Solbritt S; van der Helm-van Mil, Annette H M AH
Heritability and genomics of gene expression in peripheral blood.
Nature Genetics
Wright, Fred A FA; Sullivan, Patrick F PF; Brooks, Andrew I AI; Zou, Fei F; Sun, Wei W; Xia, Kai K; Madar, Vered V; Jansen, Rick R; Chung, Wonil W; Zhou, Yi-Hui YH; Abdellaoui, Abdel A; Batista, Sandra S; Butler, Casey C; Chen, Guanhua G; Chen, Ting-Huei TH; D'Ambrosio, David D; Gallins, Paul P; Ha, Min Jin MJ; Hottenga, Jouke Jan JJ; Huang, Shunping S; Kattenberg, Mathijs M; Kochar, Jaspreet J; Middeldorp, Christel M CM; Qu, Ani A; Shabalin, Andrey A; Tischfield, Jay J; Todd, Laura L; Tzeng, Jung-Ying JY; van Grootheest, Gerard G; Vink, Jacqueline M JM; Wang, Qi Q; Wang, Wei W; Wang, Weibo W; Willemsen, Gonneke G; Smit, Johannes H JH; de Geus, Eco J EJ; Yin, Zhaoyu Z; Penninx, Brenda W J H BW; Boomsma, Dorret I DI
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.
Nature Genetics
Stahl, Eli A EA; Raychaudhuri, Soumya S; Remmers, Elaine F EF; Xie, Gang G; Eyre, Stephen S; Thomson, Brian P BP; Li, Yonghong Y; Kurreeman, Fina A S FA; Zhernakova, Alexandra A; Hinks, Anne A; Guiducci, Candace C; Chen, Robert R; Alfredsson, Lars L; Amos, Christopher I CI; Ardlie, Kristin G KG; , ; Barton, Anne A; Bowes, John J; Brouwer, Elisabeth E; Burtt, Noel P NP; Catanese, Joseph J JJ; Coblyn, Jonathan J; Coenen, Marieke J H MJ; Costenbader, Karen H KH; Criswell, Lindsey A LA; Crusius, J Bart A JB; Cui, Jing J; de Bakker, Paul I W PI; De Jager, Philip L PL; Ding, Bo B; Emery, Paul P; Flynn, Edward E; Harrison, Pille P; Hocking, Lynne J LJ; Huizinga, Tom W J TW; Kastner, Daniel L DL; Ke, Xiayi X; Lee, Annette T AT; Liu, Xiangdong X; Martin, Paul P; Morgan, Ann W AW; Padyukov, Leonid L; Posthumus, Marcel D MD; Radstake, Timothy R D J TR; Reid, David M DM; Seielstad, Mark M; Seldin, Michael F MF; Shadick, Nancy A NA; Steer, Sophia S; Tak, Paul P PP; Thomson, Wendy W; van der Helm-van Mil, Annette H M AH; van der Horst-Bruinsma, Irene E IE; van der Schoot, C Ellen CE; van Riel, Piet L C M PL; Weinblatt, Michael E ME; Wilson, Anthony G AG; Wolbink, Gert Jan GJ; Wordsworth, B Paul BP; , ; Wijmenga, Cisca C; Karlson, Elizabeth W EW; Toes, Rene E M RE; de Vries, Niek N; Begovich, Ann B AB; Worthington, Jane J; Siminovitch, Katherine A KA; Gregersen, Peter K PK; Klareskog, Lars L; Plenge, Robert M RM
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.
Nature Genetics
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