Impact of Functional Polymorphisms on Drug Survival of Biological Therapies in Patients with Moderate-to-Severe Psoriasis.
International Journal Of Molecular Sciences
Membrive-Jiménez, Cristina C; Pérez-Ramírez, Cristina C; Arias-Santiago, Salvador S; Richetta, Antonio Giovanni AG; Ottini, Laura L; Pineda-Lancheros, Laura Elena LE; Ramírez-Tortosa, Maria Del Carmen MDC; Jiménez-Morales, Alberto A
Influence of Genetics on the Response to Omalizumab in Patients with Severe Uncontrolled Asthma with an Allergic Phenotype.
International Journal Of Molecular Sciences
Rojo-Tolosa, Susana S; Sánchez-Martínez, José Antonio JA; Pineda-Lancheros, Laura Elena LE; Gálvez-Navas, José María JM; González-Gutiérrez, María Victoria MV; Jiménez-Gálvez, Gonzalo G; Pérez-Ramírez, Cristina C; Morales-García, Concepción C; Jiménez-Morales, Alberto A
Modeling of clinical phenotypes in systemic lupus erythematosus based on the platelet transcriptome and FCGR2a genotype.
Journal Of Translational Medicine
Cornwell, MacIntosh G MG; Bannoudi, Hanane El HE; Luttrell-Williams, Elliot E; Engel, Alexis A; Barrett, Tessa J TJ; Myndzar, Khrystyna K; Izmirly, Peter P; Belmont, H Michael HM; Clancy, Robert R; Ruggles, Kelly V KV; Buyon, Jill P JP; Berger, Jeffrey S JS
Perspectives of Therapeutic Drug Monitoring of Biological Agents in Non-Infectious Uveitis Treatment: A Review.
Pharmaceutics
Busto-Iglesias, Manuel M; Rodríguez-Martínez, Lorena L; Rodríguez-Fernández, Carmen Antía CA; González-López, Jaime J; González-Barcia, Miguel M; de Domingo, Begoña B; Rodríguez-Rodríguez, Luis L; Fernández-Ferreiro, Anxo A; Mondelo-García, Cristina C
Personalized Medicine in Infant Population with Cancer: Pharmacogenetic Pilot Study of Polymorphisms Related to Toxicity and Response to Chemotherapy.
Cancers
Urtasun, Andrea A; Olivera, Gladys G GG; Sendra, Luis L; Aliño, Salvador F SF; Berlanga, Pablo P; Gargallo, Pablo P; Hervás, David D; Balaguer, Julia J; Juan-Ribelles, Antonio A; Andrés, María Del Mar MDM; Cañete, Adela A; Herrero, María José MJ
Tumor biomarkers and efficacy in patients treated with trastuzumab emtansine + pertuzumab versus standard of care in HER2-positive early breast cancer: an open-label, phase III study (KRISTINE).
Breast Cancer Research : Bcr
de Haas, Sanne L SL; Slamon, Dennis J DJ; Martin, Miguel M; Press, Michael F MF; Lewis, Gail D GD; Lambertini, Chiara C; Prat, Aleix A; Lopez-Valverde, Vanesa V; Boulet, Thomas T; Hurvitz, Sara A SA
The relationship of E-selectin singlenucleotide polymorphisms with breast cancer in Iraqi Arab women.
Genomics & Informatics
Zakariya, Bilal Fadıl BF; Almohaidi, Asmaa M Salih AMS; Şimşek, Seçil Akıllı SA; Al-Waysi, Safaa A SA; Al-Dabbagh, Wijdan H WH; Kamal, Areege Mustafa AM
Fc receptor engagement of HIV-1 Env-specific antibodies in mothers and infants predicts reduced vertical transmission.
Frontiers In Immunology
Barrows, Brittani M BM; Krebs, Shelly J SJ; Jian, Ningbo N; Zemil, Michelle M; Slike, Bonnie M BM; Dussupt, Vincent V; Tran, Ursula U; Mendez-Rivera, Letzibeth L; Chang, David D; O'Sullivan, Anne Marie AM; Mann, Brendan B; Sanders-Buell, Eric E; Shubin, Zhanna Z; Creegan, Matt M; Paquin-Proulx, Dominic D; Ehrenberg, Philip P; Laurence-Chenine, Agnes A; Srithanaviboonchai, Kriengkrai K; Thomas, Rasmi R; Eller, Michael A MA; Ferrari, Guido G; Robb, Merlin M; Rao, Venigalla V; Tovanabutra, Sodsai S; Polonis, Victoria R VR; Wieczorek, Lindsay L
Comprehensive genetic and functional analyses of Fc gamma receptors influence on response to rituximab therapy for autoimmunity.
Ebiomedicine
Robinson, James I JI; Md Yusof, Md Yuzaiful MY; Davies, Vinny V; Wild, Dawn D; Morgan, Michael M; Taylor, John C JC; El-Sherbiny, Yasser Y; Morris, David L DL; Liu, Lu L; Rawstron, Andy C AC; Buch, Maya H MH; Plant, Darren D; Cordell, Heather J HJ; Isaacs, John D JD; Bruce, Ian N IN; Emery, Paul P; Barton, Anne A; Vyse, Timothy J TJ; Barrett, Jennifer H JH; Vital, Edward M EM; Morgan, Ann W AW; , ; ,
SOD2 Gene Variants (rs4880 and rs5746136) and Their Association with Breast Cancer Risk.
Current Issues In Molecular Biology
Gallegos-Arreola, Martha P MP; Ramírez-Patiño, Ramiro R; Sánchez-López, Josefina Y JY; Zúñiga-González, Guillermo M GM; Figuera, Luis E LE; Delgado-Saucedo, Jorge I JI; Gómez-Meda, Belinda C BC; Rosales-Reynoso, Mónica A MA; Puebla-Pérez, Ana M AM; Lemus-Varela, María L ML; Garibaldi-Ríos, Asbiel F AF; Marín-Domínguez, Nayely A NA; Pacheco-Verduzco, Diana P DP; Mohamed-Flores, Emaan A EA
Analysis of systemic epigenetic alterations in inflammatory bowel disease: defining geographical, genetic, and immune-inflammatory influences on the circulating methylome.
Journal Of Crohn'S & Colitis
Kalla, R R; Adams, A T AT; Nowak, J K JK; Bergemalm, D D; Vatn, S S; Ventham, N T NT; Kennedy, N A NA; Ricanek, P P; Lindstrom, J J; , ; Söderholm, J J; Pierik, M M; D'Amato, M M; Gomollón, F F; Olbjorn, C C; Richmond, R R; Relton, C L CL; Jahnsen, J J; Vatn, M H MH; Halfvarson, J J; Satsangi, J J
A systems genomics approach to uncover patient-specific pathogenic pathways and proteins in ulcerative colitis.
Nature Communications
Brooks-Warburton, Johanne J; Modos, Dezso D; Sudhakar, Padhmanand P; Madgwick, Matthew M; Thomas, John P JP; Bohar, Balazs B; Fazekas, David D; Zoufir, Azedine A; Kapuy, Orsolya O; Szalay-Beko, Mate M; Verstockt, Bram B; Hall, Lindsay J LJ; Watson, Alastair A; Tremelling, Mark M; Parkes, Miles M; Vermeire, Severine S; Bender, Andreas A; Carding, Simon R SR; Korcsmaros, Tamas T
Development of a prognostic nomogram based on an eight-gene signature for esophageal squamous cell carcinoma by weighted gene co-expression network analysis (WGCNA).
Annals Of Translational Medicine
Xie, Jiahong J; Yang, Pingshan P; Wei, Hongjian H; Mai, Peiwen P; Yu, Xiaoli X
The FCGR2A rs1801274 polymorphism was associated with the risk of death among COVID-19 patients.
Clinical Immunology (Orlando, Fla.)
López-Martínez, Rocío R; Albaiceta, Guillermo M GM; Amado-Rodríguez, Laura L; Cuesta-Llavona, Elías E; Gómez, Juan J; García-Clemente, Marta M; Vázquez-Coto, Daniel D; Alvarez, Victoria V; Coto, Eliecer E
The FCGR2Ars1801274 polymorphism was associated with the risk of death among COVID-19 patients.
Clinical Immunology (Orlando, Fla.)
López-Martínez, Rocío R; Albaiceta, Guillermo M GM; Amado-Rodríguez, Laura L; Cuesta-Llavona, Elías E; Gómez, Juan J; García-Clemente, Marta M; Vázquez-Coto, Daniel D; Alvarez, Victoria V; Coto, Eliecer E
Model-Based Characterization of the Bidirectional Interaction Between Pharmacokinetics and Tumor Growth Dynamics in Patients with Metastatic Merkel Cell Carcinoma Treated with Avelumab.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Grisic, Ana-Marija AM; Xiong, Wenyuan W; Tanneau, Lénaïg L; Jönsson, Siv S; Friberg, Lena E LE; Karlsson, Mats O MO; Dai, Haiqing H; Zheng, Jenny J; Girard, Pascal P; Khandelwal, Akash A
Synergistic insights into human health from aptamer- and antibody-based proteomic profiling.
Nature Communications
Pietzner, Maik M; Wheeler, Eleanor E; Carrasco-Zanini, Julia J; Kerrison, Nicola D ND; Oerton, Erin E; Koprulu, Mine M; Luan, Jian'an J; Hingorani, Aroon D AD; Williams, Steve A SA; Wareham, Nicholas J NJ; Langenberg, Claudia C
Synergistic insights into human health from aptamer- and antibody-based proteomic profiling.
Nature Communications
Pietzner, Maik M; Wheeler, Eleanor E; Carrasco-Zanini, Julia J; Kerrison, Nicola D ND; Oerton, Erin E; Koprulu, Mine M; Luan, Jian'an J; Hingorani, Aroon D AD; Williams, Steve A SA; Wareham, Nicholas J NJ; Langenberg, Claudia C
Epione application: An integrated web‑toolkit of clinical genomics and personalized medicine in systemic lupus erythematosus.
International Journal Of Molecular Medicine
Papageorgiou, Louis L; Alkenaris, Haris H; Zervou, Maria I MI; Vlachakis, Dimitriοs D; Matalliotakis, Ioannis I; Spandidos, Demetrios A DA; Bertsias, George G; Goulielmos, George N GN; Eliopoulos, Elias E
Ustekinumab Dosing Individualization in Crohn's Disease Guided by a Population Pharmacokinetic-Pharmacodynamic Model.
Pharmaceutics
Aguiar Zdovc, Jurij J; Hanžel, Jurij J; Kurent, Tina T; Sever, Nejc N; Koželj, Matic M; Smrekar, Nataša N; Novak, Gregor G; Štabuc, Borut B; Dreesen, Erwin E; Thomas, Debby D; Vovk, Tomaž T; Ostanek, Barbara B; Drobne, David D; Grabnar, Iztok I
Significant differences in FcγRIIa, FcγRIIIa and FcγRIIIb genes polymorphism and anti-malarial IgG subclass pattern are associated with severe Plasmodium falciparum malaria in Saudi children.
Malaria Journal
Nasr, Amre A; Aljada, Ahmad A; Hamid, Osama O; Elsheikh, Hatim A HA; Masuadi, Emad E; Al-Bawab, Ahmad A; Alenazi, Themer H TH; Abushouk, Amir A; Salah, Ayman M AM
Functional Fc Gamma Receptor Gene Polymorphisms and Long-Term Kidney Allograft Survival.
Frontiers In Immunology
Wahrmann, Markus M; Döhler, Bernd B; Arnold, Marie-Luise ML; Scherer, Sabine S; Mayer, Katharina A KA; Haindl, Susanne S; Haslacher, Helmuth H; Böhmig, Georg A GA; Süsal, Caner C
Functional genomics atlas of synovial fibroblasts defining rheumatoid arthritis heritability.
Genome Biology
Ge, Xiangyu X; Frank-Bertoncelj, Mojca M; Klein, Kerstin K; McGovern, Amanda A; Kuret, Tadeja T; Houtman, Miranda M; Burja, Blaž B; Micheroli, Raphael R; Shi, Chenfu C; Marks, Miriam M; Filer, Andrew A; Buckley, Christopher D CD; Orozco, Gisela G; Distler, Oliver O; Morris, Andrew P AP; Martin, Paul P; Eyre, Stephen S; Ospelt, Caroline C
Immunomonitoring of Stage IV Relapsed Neuroblastoma Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplantation and Subsequent GD2 (ch14.18/CHO) Antibody Treatment.
Frontiers In Immunology
Seitz, Christian Martin CM; Flaadt, Tim T; Mezger, Markus M; Lang, Anne-Marie AM; Michaelis, Sebastian S; Katz, Marie M; Syring, Desireé D; Joechner, Alexander A; Rabsteyn, Armin A; Siebert, Nikolai N; Troschke-Meurer, Sascha S; Zumpe, Maxi M; Lode, Holger N HN; Yang, Sile F SF; Atar, Daniel D; Mast, Anna-Sophia AS; Scheuermann, Sophia S; Heubach, Florian F; Handgretinger, Rupert R; Lang, Peter P; Schlegel, Patrick P
Single-nucleotide Fcγ receptor polymorphisms do not impact obinutuzumab/rituximab outcome in patients with lymphoma.
Blood Advances
Strefford, Jonathan C JC; Nowicka, Malgorzata M; Hargreaves, Chantal E CE; Burton, Cathy C; Davies, Andrew A; Ganderton, Rosalind R; Hiddemann, Wolfgang W; Iriyama, Chisako C; Klapper, Wolfram W; Latham, Kate V KV; Martelli, Maurizio M; Mir, Farheen F; Parker, Helen H; Potter, Kathleen N KN; Rose-Zerilli, Matthew J J MJJ; Sehn, Laurie H LH; Trněný, Marek M; Vitolo, Umberto U; Bolen, Christopher R CR; Klein, Christian C; Knapp, Andrea A; Oestergaard, Mikkel Z MZ; Cragg, Mark S MS