Impact of Functional Polymorphisms on Drug Survival of Biological Therapies in Patients with Moderate-to-Severe Psoriasis.
International Journal Of Molecular Sciences
Membrive-Jiménez, Cristina C; Pérez-Ramírez, Cristina C; Arias-Santiago, Salvador S; Richetta, Antonio Giovanni AG; Ottini, Laura L; Pineda-Lancheros, Laura Elena LE; Ramírez-Tortosa, Maria Del Carmen MDC; Jiménez-Morales, Alberto A
Influence of Genetics on the Response to Omalizumab in Patients with Severe Uncontrolled Asthma with an Allergic Phenotype.
International Journal Of Molecular Sciences
Rojo-Tolosa, Susana S; Sánchez-Martínez, José Antonio JA; Pineda-Lancheros, Laura Elena LE; Gálvez-Navas, José María JM; González-Gutiérrez, María Victoria MV; Jiménez-Gálvez, Gonzalo G; Pérez-Ramírez, Cristina C; Morales-García, Concepción C; Jiménez-Morales, Alberto A
Modeling of clinical phenotypes in systemic lupus erythematosus based on the platelet transcriptome and FCGR2a genotype.
Journal Of Translational Medicine
Cornwell, MacIntosh G MG; Bannoudi, Hanane El HE; Luttrell-Williams, Elliot E; Engel, Alexis A; Barrett, Tessa J TJ; Myndzar, Khrystyna K; Izmirly, Peter P; Belmont, H Michael HM; Clancy, Robert R; Ruggles, Kelly V KV; Buyon, Jill P JP; Berger, Jeffrey S JS
Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.
Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Perspectives of Therapeutic Drug Monitoring of Biological Agents in Non-Infectious Uveitis Treatment: A Review.
Pharmaceutics
Busto-Iglesias, Manuel M; Rodríguez-Martínez, Lorena L; Rodríguez-Fernández, Carmen Antía CA; González-López, Jaime J; González-Barcia, Miguel M; de Domingo, Begoña B; Rodríguez-Rodríguez, Luis L; Fernández-Ferreiro, Anxo A; Mondelo-García, Cristina C
Personalized Medicine in Infant Population with Cancer: Pharmacogenetic Pilot Study of Polymorphisms Related to Toxicity and Response to Chemotherapy.
Cancers
Urtasun, Andrea A; Olivera, Gladys G GG; Sendra, Luis L; Aliño, Salvador F SF; Berlanga, Pablo P; Gargallo, Pablo P; Hervás, David D; Balaguer, Julia J; Juan-Ribelles, Antonio A; Andrés, María Del Mar MDM; Cañete, Adela A; Herrero, María José MJ
Kawasaki disease in Malaysia: Biochemical profile, characterization, diagnosis and treatment.
Frontiers In Pediatrics
Cheah, Chooi San CS; Lee, Wendy Wei Li WWL; Suhaini, Siti Aisyah SA; Azidin, Abdullah Harith AH; Khoo, Mohammad Shukri MS; Ismail, Noor Akmal Shareela NAS; Ali, Adli A
Tumor biomarkers and efficacy in patients treated with trastuzumab emtansine + pertuzumab versus standard of care in HER2-positive early breast cancer: an open-label, phase III study (KRISTINE).
Breast Cancer Research : Bcr
de Haas, Sanne L SL; Slamon, Dennis J DJ; Martin, Miguel M; Press, Michael F MF; Lewis, Gail D GD; Lambertini, Chiara C; Prat, Aleix A; Lopez-Valverde, Vanesa V; Boulet, Thomas T; Hurvitz, Sara A SA
The relationship of E-selectin singlenucleotide polymorphisms with breast cancer in Iraqi Arab women.
Genomics & Informatics
Zakariya, Bilal Fadıl BF; Almohaidi, Asmaa M Salih AMS; Şimşek, Seçil Akıllı SA; Al-Waysi, Safaa A SA; Al-Dabbagh, Wijdan H WH; Kamal, Areege Mustafa AM
Fc receptor engagement of HIV-1 Env-specific antibodies in mothers and infants predicts reduced vertical transmission.
Frontiers In Immunology
Barrows, Brittani M BM; Krebs, Shelly J SJ; Jian, Ningbo N; Zemil, Michelle M; Slike, Bonnie M BM; Dussupt, Vincent V; Tran, Ursula U; Mendez-Rivera, Letzibeth L; Chang, David D; O'Sullivan, Anne Marie AM; Mann, Brendan B; Sanders-Buell, Eric E; Shubin, Zhanna Z; Creegan, Matt M; Paquin-Proulx, Dominic D; Ehrenberg, Philip P; Laurence-Chenine, Agnes A; Srithanaviboonchai, Kriengkrai K; Thomas, Rasmi R; Eller, Michael A MA; Ferrari, Guido G; Robb, Merlin M; Rao, Venigalla V; Tovanabutra, Sodsai S; Polonis, Victoria R VR; Wieczorek, Lindsay L
Comprehensive genetic and functional analyses of Fc gamma receptors influence on response to rituximab therapy for autoimmunity.
Ebiomedicine
Robinson, James I JI; Md Yusof, Md Yuzaiful MY; Davies, Vinny V; Wild, Dawn D; Morgan, Michael M; Taylor, John C JC; El-Sherbiny, Yasser Y; Morris, David L DL; Liu, Lu L; Rawstron, Andy C AC; Buch, Maya H MH; Plant, Darren D; Cordell, Heather J HJ; Isaacs, John D JD; Bruce, Ian N IN; Emery, Paul P; Barton, Anne A; Vyse, Timothy J TJ; Barrett, Jennifer H JH; Vital, Edward M EM; Morgan, Ann W AW; , ; ,
SOD2 Gene Variants (rs4880 and rs5746136) and Their Association with Breast Cancer Risk.
Current Issues In Molecular Biology
Gallegos-Arreola, Martha P MP; Ramírez-Patiño, Ramiro R; Sánchez-López, Josefina Y JY; Zúñiga-González, Guillermo M GM; Figuera, Luis E LE; Delgado-Saucedo, Jorge I JI; Gómez-Meda, Belinda C BC; Rosales-Reynoso, Mónica A MA; Puebla-Pérez, Ana M AM; Lemus-Varela, María L ML; Garibaldi-Ríos, Asbiel F AF; Marín-Domínguez, Nayely A NA; Pacheco-Verduzco, Diana P DP; Mohamed-Flores, Emaan A EA
Beneficial effects of mifepristone treatment in breast cancer patients selected by the progesterone receptor isoform ratio: Results from the MIPRA trial.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Elía, Andrés A; Saldain, Leo L; Vanzulli, Silvia I SI; Helguero, Luisa A LA; Lamb, Caroline A CA; Fabris, Victoria V; Pataccini, Gabriela G; Martínez-Vazquez, Paula P; Burruchaga, Javier J; Caillet-Bois, Ines I; Spengler, Eunice E; Acosta Haab, Gabriela G; Liguori, Marcos M; Castets, Alejandra A; Lovisi, Silvia S; Abascal, María F MF; Novaro, Virginia V; Sánchez, Jana J; Muñoz, Javier J; Belizán, Jose M JM; Abba, Martín C MC; Gass, Hugo H; Rojas, Paola P; Lanari, Claudia C
Publication Date: 2022-10-21
Variant appearance in text: FCGR2A: 500A>G; His167Arg; rs1801274
Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.
Scientific Reports
Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
Analysis of systemic epigenetic alterations in inflammatory bowel disease: defining geographical, genetic, and immune-inflammatory influences on the circulating methylome.
Journal Of Crohn'S & Colitis
Kalla, R R; Adams, A T AT; Nowak, J K JK; Bergemalm, D D; Vatn, S S; Ventham, N T NT; Kennedy, N A NA; Ricanek, P P; Lindstrom, J J; , ; Söderholm, J J; Pierik, M M; D'Amato, M M; Gomollón, F F; Olbjorn, C C; Richmond, R R; Relton, C L CL; Jahnsen, J J; Vatn, M H MH; Halfvarson, J J; Satsangi, J J
Epigenetic profiling linked to multisystem inflammatory syndrome in children (MIS-C): A multicenter, retrospective study.
Eclinicalmedicine
Davalos, Veronica V; García-Prieto, Carlos A CA; Ferrer, Gerardo G; Aguilera-Albesa, Sergio S; Valencia-Ramos, Juan J; Rodríguez-Palmero, Agustí A; Ruiz, Montserrat M; Planas-Serra, Laura L; Jordan, Iolanda I; Alegría, Iosune I; Flores-Pérez, Patricia P; Cantarín, Verónica V; Fumadó, Victoria V; Viadero, Maria Teresa MT; Rodrigo, Carlos C; Méndez-Hernández, Maria M; López-Granados, Eduardo E; Colobran, Roger R; Rivière, Jacques G JG; Soler-Palacín, Pere P; Pujol, Aurora A; Esteller, Manel M
Genomic, transcriptomic, and metabolomic profiles of hiPSC-derived dopamine neurons from clinically discordant brothers with identical PRKN deletions.
Npj Parkinson'S Disease
Cukier, Holly N HN; Kim, Hyunjin H; Griswold, Anthony J AJ; Codreanu, Simona G SG; Prince, Lisa M LM; Sherrod, Stacy D SD; McLean, John A JA; Dykxhoorn, Derek M DM; Ess, Kevin C KC; Hedera, Peter P; Bowman, Aaron B AB; Neely, M Diana MD
Publication Date: 2022-06-29
Variant appearance in text: FCGR2A: H167R; rs1801274
Integrated DNA and RNA Sequencing Reveals Drivers of Endocrine Resistance in Estrogen Receptor-Positive Breast Cancer.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Xia, Youli Y; He, Xiaping X; Renshaw, Lorna L; Martinez-Perez, Carlos C; Kay, Charlene C; Gray, Mark M; Meehan, James J; Parker, Joel S JS; Perou, Charles M CM; Carey, Lisa A LA; Dixon, J Michael JM; Turnbull, Arran A
Publication Date: 2022-08-15
Variant appearance in text: FCGR2A: H167R; rs1801274
A systems genomics approach to uncover patient-specific pathogenic pathways and proteins in ulcerative colitis.
Nature Communications
Brooks-Warburton, Johanne J; Modos, Dezso D; Sudhakar, Padhmanand P; Madgwick, Matthew M; Thomas, John P JP; Bohar, Balazs B; Fazekas, David D; Zoufir, Azedine A; Kapuy, Orsolya O; Szalay-Beko, Mate M; Verstockt, Bram B; Hall, Lindsay J LJ; Watson, Alastair A; Tremelling, Mark M; Parkes, Miles M; Vermeire, Severine S; Bender, Andreas A; Carding, Simon R SR; Korcsmaros, Tamas T
Development of a prognostic nomogram based on an eight-gene signature for esophageal squamous cell carcinoma by weighted gene co-expression network analysis (WGCNA).
Annals Of Translational Medicine
Xie, Jiahong J; Yang, Pingshan P; Wei, Hongjian H; Mai, Peiwen P; Yu, Xiaoli X
Integrated molecular profiling of patient-derived ovarian cancer models identifies clinically relevant signatures and tumor vulnerabilities.
International Journal Of Cancer
Lupia, Michela M; Melocchi, Valentina V; Bizzaro, Francesca F; Lo Riso, Pietro P; Dama, Elisa E; Baronio, Micol M; Ranghiero, Alberto A; Barberis, Massimo M; Bernard, Loris L; Bertalot, Giovanni G; Giavazzi, Raffaella R; Testa, Giuseppe G; Bianchi, Fabrizio F; Cavallaro, Ugo U
Publication Date: 2022-07-15
Variant appearance in text: FCGR2A: His167Arg; rs1801274
The FCGR2Ars1801274 polymorphism was associated with the risk of death among COVID-19 patients.
Clinical Immunology (Orlando, Fla.)
López-Martínez, Rocío R; Albaiceta, Guillermo M GM; Amado-Rodríguez, Laura L; Cuesta-Llavona, Elías E; Gómez, Juan J; García-Clemente, Marta M; Vázquez-Coto, Daniel D; Alvarez, Victoria V; Coto, Eliecer E
The FCGR2A rs1801274 polymorphism was associated with the risk of death among COVID-19 patients.
Clinical Immunology (Orlando, Fla.)
López-Martínez, Rocío R; Albaiceta, Guillermo M GM; Amado-Rodríguez, Laura L; Cuesta-Llavona, Elías E; Gómez, Juan J; García-Clemente, Marta M; Vázquez-Coto, Daniel D; Alvarez, Victoria V; Coto, Eliecer E
Model-Based Characterization of the Bidirectional Interaction Between Pharmacokinetics and Tumor Growth Dynamics in Patients with Metastatic Merkel Cell Carcinoma Treated with Avelumab.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Grisic, Ana-Marija AM; Xiong, Wenyuan W; Tanneau, Lénaïg L; Jönsson, Siv S; Friberg, Lena E LE; Karlsson, Mats O MO; Dai, Haiqing H; Zheng, Jenny J; Girard, Pascal P; Khandelwal, Akash A