Publications:

---

Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: FMO3: 458C>T; Pro153Leu

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

---

Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines.

Nature Neuroscience

Baxi, Emily G EG; Thompson, Terri T; Li, Jonathan J; Kaye, Julia A JA; Lim, Ryan G RG; Wu, Jie J; Ramamoorthy, Divya D; Lima, Leandro L; Vaibhav, Vineet V; Matlock, Andrea A; Frank, Aaron A; Coyne, Alyssa N AN; Landin, Barry B; Ornelas, Loren L; Mosmiller, Elizabeth E; Thrower, Sara S; Farr, S Michelle SM; Panther, Lindsey L; Gomez, Emilda E; Galvez, Erick E; Perez, Daniel D; Meepe, Imara I; Lei, Susan S; Mandefro, Berhan B; Trost, Hannah H; Pinedo, Louis L; Banuelos, Maria G MG; Liu, Chunyan C; Moran, Ruby R; Garcia, Veronica V; Workman, Michael M; Ho, Richie R; Wyman, Stacia S; Roggenbuck, Jennifer J; Harms, Matthew B MB; Stocksdale, Jennifer J; Miramontes, Ricardo R; Wang, Keona K; Venkatraman, Vidya V; Holewenski, Ronald R; Sundararaman, Niveda N; Pandey, Rakhi R; Manalo, Danica-Mae DM; Donde, Aneesh A; Huynh, Nhan N; Adam, Miriam M; Wassie, Brook T BT; Vertudes, Edward E; Amirani, Naufa N; Raja, Krishna K; Thomas, Reuben R; Hayes, Lindsey L; Lenail, Alex A; Cerezo, Aianna A; Luppino, Sarah S; Farrar, Alanna A; Pothier, Lindsay L; Prina, Carolyn C; Morgan, Todd T; Jamil, Arish A; Heintzman, Sarah S; Jockel-Balsarotti, Jennifer J; Karanja, Elizabeth E; Markway, Jesse J; McCallum, Molly M; Joslin, Ben B; Alibazoglu, Deniz D; Kolb, Stephen S; Ajroud-Driss, Senda S; Baloh, Robert R; Heitzman, Daragh D; Miller, Tim T; Glass, Jonathan D JD; Patel-Murray, Natasha Leanna NL; Yu, Hong H; Sinani, Ervin E; Vigneswaran, Prasha P; Sherman, Alexander V AV; Ahmad, Omar O; Roy, Promit P; Beavers, Jay C JC; Zeiler, Steven S; Krakauer, John W JW; Agurto, Carla C; Cecchi, Guillermo G; Bellard, Mary M; Raghav, Yogindra Y; Sachs, Karen K; Ehrenberger, Tobias T; Bruce, Elizabeth E; Cudkowicz, Merit E ME; Maragakis, Nicholas N; Norel, Raquel R; Van Eyk, Jennifer E JE; Finkbeiner, Steven S; Berry, James J; Sareen, Dhruv D; Thompson, Leslie M LM; Fraenkel, Ernest E; Svendsen, Clive N CN; Rothstein, Jeffrey D JD

Publication Date: 2022-02

Variant appearance in text: FMO3: P153L; rs72549326

PubMed Link: 35115730

Variant Present in the following documents:

• 41593_2021_1006_MOESM4_ESM.xlsx, sheet 9
• 41593_2021_1006_MOESM4_ESM.xlsx, sheet 7
• 41593_2021_1006_MOESM4_ESM.xlsx, sheet 8

View BVdb publication page

---

Adaptive Modelling of Mutated FMO3 Enzyme Could Unveil Unexplored Scenarios Linking Variant Haplotypes to TMAU Phenotypes.

Molecules (Basel, Switzerland)

Alibrandi, Simona S; Nicita, Fabiana F; Donato, Luigi L; Scimone, Concetta C; Rinaldi, Carmela C; D'Angelo, Rosalia R; Sidoti, Antonina A

Publication Date: 2021-11-22

Variant appearance in text: FMO3: 458C>T; P153L

PubMed Link: 34834137

Variant Present in the following documents:

• Main text
• molecules-26-07045.pdf

View BVdb publication page

---

Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform.

Translational And Clinical Pharmacology

Kim, Byungwook B; Yoon, Deok Yong DY; Lee, SeungHwan S; Jang, In-Jin IJ; Yu, Kyung-Sang KS; Cho, Joo-Youn JY; Oh, Jaeseong J

Publication Date: 2021-09

Variant appearance in text: FMO3: 458C>T; P153L; rs72549326

PubMed Link: 34621706

Variant Present in the following documents:

• tcp-29-135-s001.xls, sheet 1

View BVdb publication page

---

The prevalence, genetic complexity and population-specific founder effects of human autosomal recessive disorders.

Npj Genomic Medicine

Xiao, Qingyang Q; Lauschke, Volker M VM

Publication Date: 2021-06-02

Variant appearance in text: FMO3: 458C>T; Pro153Leu; rs72549326

PubMed Link: 34078906

Variant Present in the following documents:

• 41525_2021_203_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

---

Impact of trimethylaminuria on daily psychosocial functioning.

Jimd Reports

Roddy, Daniel D; McCarthy, Philomena P; Nerney, Darragh D; Mulligan-Rabbitt, Jennifer J; Smith, Edwin E; Treacy, Eileen P EP

Publication Date: 2021-01

Variant appearance in text: FMO3: 458C>T; Pro153Leu

PubMed Link: 33473342

Variant Present in the following documents:

• Main text
• JMD2-57-67.pdf

View BVdb publication page

---

Population Pharmacokinetic and Pharmacogenetic Analysis of Mitotane in Patients with Adrenocortical Carcinoma: Towards Individualized Dosing.

Clinical Pharmacokinetics

Yin, Anyue A; Ettaieb, Madeleine H T MHT; Swen, Jesse J JJ; van Deun, Liselotte L; Kerkhofs, Thomas M A TMA; van der Straaten, Robert J H M RJHM; Corssmit, Eleonora P M EPM; Gelderblom, Hans H; Kerstens, Michiel N MN; Feelders, Richard A RA; Eekhoff, Marelise M; Timmers, Henri J L M HJLM; D'Avolio, Antonio A; Cusato, Jessica J; Guchelaar, Henk-Jan HJ; Haak, Harm R HR; Moes, Dirk Jan A R DJAR

Publication Date: 2021-01

Variant appearance in text: FMO3: 458C>T; P153L; rs72549326

PubMed Link: 32607875

Variant Present in the following documents:

• 40262_2020_913_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

---

Precision medicine integrating whole-genome sequencing, comprehensive metabolomics, and advanced imaging.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Hou, Ying-Chen Claire YC; Yu, Hung-Chun HC; Martin, Rick R; Cirulli, Elizabeth T ET; Schenker-Ahmed, Natalie M NM; Hicks, Michael M; Cohen, Isaac V IV; Jönsson, Thomas J TJ; Heister, Robyn R; Napier, Lori L; Swisher, Christine Leon CL; Dominguez, Saints S; Tang, Haibao H; Li, Weizhong W; Perkins, Bradley A BA; Barea, Jaime J; Rybak, Christina C; Smith, Emily E; Duchicela, Keegan K; Doney, Michael M; Brar, Pamila P; Hernandez, Nathaniel N; Kirkness, Ewen F EF; Kahn, Andrew M AM; Venter, J Craig JC; Karow, David S DS; Caskey, C Thomas CT

Publication Date: 2020-02-11

Variant appearance in text: FMO3: 458C>T

PubMed Link: 31980526

Variant Present in the following documents:

• pnas.1909378117.sd01.xlsx, sheet 1

View BVdb publication page

---

Optimizing clinical exome design and parallel gene-testing for recessive genetic conditions in preconception carrier screening: Translational research genomic data from 14,125 exomes.

Plos Genetics

Capalbo, Antonio A; Valero, Roberto Alonso RA; Jimenez-Almazan, Jorge J; Pardo, Pere Mir PM; Fabiani, Marco M; Jiménez, David D; Simon, Carlos C; Rodriguez, Julio Martin JM

Publication Date: 2019-10

Variant appearance in text: FMO3: 458C>T; Pro153Leu; rs72549326

PubMed Link: 31589614

Variant Present in the following documents:

• pgen.1008409.s001.xlsx, sheet 1

View BVdb publication page

---

Diagnosis and phenotypic assessment of trimethylaminuria, and its treatment with riboflavin: 1H NMR spectroscopy and genetic testing.

Orphanet Journal Of Rare Diseases

Bouchemal, Nadia N; Ouss, Lisa L; Brassier, Anaïs A; Barbier, Valérie V; Gobin, Stéphanie S; Hubert, Laurence L; de Lonlay, Pascale P; Le Moyec, Laurence L

Publication Date: 2019-09-18

Variant appearance in text: FMO3: Pro153Leu

PubMed Link: 31533761

Variant Present in the following documents:

• Main text
• 13023_2019_Article_1174.pdf

View BVdb publication page

---

The genetic and biochemical basis of trimethylaminuria in an Irish cohort.

Jimd Reports

Doyle, Samantha S; O'Byrne, James J JJ; Nesbitt, Mandy M; Murphy, Daniel N DN; Abidin, Zaza Z; Byrne, Niall N; Pastores, Gregory G; Kirk, Richard R; Treacy, Eileen P EP

Publication Date: 2019-05

Variant appearance in text: FMO3: 458C>T; Pro153Leu

PubMed Link: 31240165

Variant Present in the following documents:

• Main text
• JMD2-47-35.pdf

View BVdb publication page

---

Association of FMO3 Variants with Blood Pressure in the Atherosclerosis Risk in Communities Study.

International Journal Of Hypertension

Bryant, Tyler S TS; Duggal, Priya P; Yu, Bing B; Morrison, Alanna C AC; Shafi, Tariq T; Ehret, Georg G; Franceschini, Nora N; Boerwinkle, Eric E; Coresh, Josef J; Tin, Adrienne A

Publication Date: 2019

Variant appearance in text: FMO3: P153L; rs72549326

PubMed Link: 30906589

Variant Present in the following documents:

• Main text
• IJHY2019-2137629.pdf

View BVdb publication page

---

Assessing the Pathogenicity, Penetrance, and Expressivity of Putative Disease-Causing Variants in a Population Setting.

American Journal Of Human Genetics

Wright, Caroline F CF; West, Ben B; Tuke, Marcus M; Jones, Samuel E SE; Patel, Kashyap K; Laver, Thomas W TW; Beaumont, Robin N RN; Tyrrell, Jessica J; Wood, Andrew R AR; Frayling, Timothy M TM; Hattersley, Andrew T AT; Weedon, Michael N MN

Publication Date: 2019-02-07

Variant appearance in text: FMO3: P153L; rs72549326

PubMed Link: 30665703

Variant Present in the following documents:

• mmc3.xlsx, sheet 1

View BVdb publication page

---

An optimized prediction framework to assess the functional impact of pharmacogenetic variants.

The Pharmacogenomics Journal

Zhou, Yitian Y; Mkrtchian, Souren S; Kumondai, Masaki M; Hiratsuka, Masahiro M; Lauschke, Volker M VM

Publication Date: 2019-04

Variant appearance in text: FMO3: P153L; rs72549326

PubMed Link: 30206299

Variant Present in the following documents:

• 41397_2018_44_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

---

Arylsulphatase A Pseudodeficiency (ARSA-PD), hypertension and chronic renal disease in Aboriginal Australians.

Scientific Reports

Tang, Dave D; Fakiola, Michaela M; Syn, Genevieve G; Anderson, Denise D; Cordell, Heather J HJ; Scaman, Elizabeth S H ESH; Davis, Elizabeth E; Miles, Simon J SJ; McLeay, Toby T; Jamieson, Sarra E SE; Lassmann, Timo T; Blackwell, Jenefer M JM

Publication Date: 2018-07-19

Variant appearance in text: FMO3: Pro153Leu; rs72549326

PubMed Link: 30026549

Variant Present in the following documents:

• 41598_2018_29279_MOESM1_ESM.pdf

View BVdb publication page

---

Genetic variation in human drug-related genes.

Genome Medicine

Schärfe, Charlotta Pauline Irmgard CPI; Tremmel, Roman R; Schwab, Matthias M; Kohlbacher, Oliver O; Marks, Debora Susan DS

Publication Date: 2017-12-22

Variant appearance in text: rs72549326

PubMed Link: 29273096

Variant Present in the following documents:

• 13073_2017_502_MOESM2_ESM.xlsx, sheet 2

View BVdb publication page

---

Comparative analysis of primary versus relapse/refractory DLBCL identifies shifts in mutation spectrum.

Oncotarget

Greenawalt, Danielle M DM; Liang, Winnie S WS; Saif, Sakina S; Johnson, Justin J; Todorov, Petar P; Dulak, Austin A; Enriquez, Daniel D; Halperin, Rebecca R; Ahmed, Ambar A; Saveliev, Vladislav V; Carpten, John J; Craig, David D; Barrett, J Carl JC; Dougherty, Brian B; Zinda, Michael M; Fawell, Stephen S; Dry, Jonathan R JR; Byth, Kate K

Publication Date: 2017-11-21

Variant appearance in text: FMO3: 458C>T; rs72549326

PubMed Link: 29245897

Variant Present in the following documents:

• oncotarget-08-99237-s002.xlsx, sheet 1
• oncotarget-08-99237-s003.xlsx, sheet 1

View BVdb publication page

---

Genetic and Nongenetic Factors Associated with Protein Abundance of Flavin-Containing Monooxygenase 3 in Human Liver.

The Journal Of Pharmacology And Experimental Therapeutics

Xu, Meijuan M; Bhatt, Deepak Kumar DK; Yeung, Catherine K CK; Claw, Katrina G KG; Chaudhry, Amarjit S AS; Gaedigk, Andrea A; Pearce, Robin E RE; Broeckel, Ulrich U; Gaedigk, Roger R; Nickerson, Deborah A DA; Schuetz, Erin E; Rettie, Allan E AE; Leeder, J Steven JS; Thummel, Kenneth E KE; Prasad, Bhagwat B

Publication Date: 2017-11

Variant appearance in text: FMO3: P153L; rs72549326

PubMed Link: 28819071

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Sources of discordance among germ-line variant classifications in ClinVar.

Genetics In Medicine : Official Journal Of The American College Of Medical Genetics

Yang, Shan S; Lincoln, Stephen E SE; Kobayashi, Yuya Y; Nykamp, Keith K; Nussbaum, Robert L RL; Topper, Scott S

Publication Date: 2017-10

Variant appearance in text: FMO3: 458C>T; Pro153Leu

PubMed Link: 28569743

Variant Present in the following documents:

• gim201760x7.xlsx, sheet 2

View BVdb publication page

---

Targeted sequencing identifies genetic polymorphisms of flavin-containing monooxygenase genes contributing to susceptibility of nicotine dependence in European American and African American.

Brain And Behavior

Zhang, Tian-Xiao TX; Saccone, Nancy L NL; Bierut, Laura J LJ; Rice, John P JP

Publication Date: 2017-04

Variant appearance in text: FMO3: P153L; rs72549326

PubMed Link: 28413702

Variant Present in the following documents:

• BRB3-7-e00651-s002.xlsx, sheet 1

View BVdb publication page

---

A compound heterozygous mutation in the FMO3 gene: the first pediatric case causes fish odor syndrome in Korea.

Korean Journal Of Pediatrics

Kim, Ji Hyun JH; Cho, Sung Min SM; Chae, Jong-Hee JH

Publication Date: 2017-03

Variant appearance in text: FMO3: Pro153Leu

PubMed Link: 28392825

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Genetic analysis of impaired trimethylamine metabolism using whole exome sequencing.

Bmc Medical Genetics

Guo, Yiran Y; Hwang, Liang-Dar LD; Li, Jiankang J; Eades, Jason J; Yu, Chung Wen CW; Mansfield, Corrine C; Burdick-Will, Alexis A; Chang, Xiao X; Chen, Yulan Y; Duke, Fujiko F FF; Zhang, Jianguo J; Fakharzadeh, Steven S; Fennessey, Paul P; Keating, Brendan J BJ; Jiang, Hui H; Hakonarson, Hakon H; Reed, Danielle R DR; Preti, George G

Publication Date: 2017-02-15

Variant appearance in text: FMO3: 458C>T; Pro153Leu; rs72549326

PubMed Link: 28196478

Variant Present in the following documents:

View BVdb publication page

---

Characterization of ADME gene variation in 21 populations by exome sequencing.

Pharmacogenetics And Genomics

Hovelson, Daniel H DH; Xue, Zhengyu Z; Zawistowski, Matthew M; Ehm, Margaret G MG; Harris, Elizabeth C EC; Stocker, Sophie L SL; Gross, Annette S AS; Jang, In-Jin IJ; Ieiri, Ichiro I; Lee, Jong-Eun JE; Cardon, Lon R LR; Chissoe, Stephanie L SL; Abecasis, Gonçalo G; Nelson, Matthew R MR

Publication Date: 2017-03

Variant appearance in text: FMO3: 458C>T; P153L; rs72549326

PubMed Link: 27984508

Variant Present in the following documents:

• fpc-27-089-s005.xlsx, sheet 2

View BVdb publication page

---

GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics

Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J

Publication Date: 2015-07-25

Variant appearance in text: FMO3: P153L

PubMed Link: 26206375

Variant Present in the following documents:

• 12859_2015_673_MOESM1_ESM.xls, sheet 1
• 12859_2015_673_MOESM2_ESM.xls, sheet 1

View BVdb publication page

---

Fish Malodour syndrome in a child.

Bmj Case Reports

Oliveira, Alexandra A; Faria, Ana A; Oliva, Mónica M

Publication Date: 2015-04-13

Variant appearance in text: FMO3: 458C>T; P153L

PubMed Link: 25870212

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Population genomic analysis of 962 whole genome sequences of humans reveals natural selection in non-coding regions.

Plos One

Yu, Fuli F; Lu, Jian J; Liu, Xiaoming X; Gazave, Elodie E; Chang, Diana D; Raj, Srilakshmi S; Hunter-Zinck, Haley H; Blekhman, Ran R; Arbiza, Leonardo L; Van Hout, Cris C; Morrison, Alanna A; Johnson, Andrew D AD; Bis, Joshua J; Cupples, L Adrienne LA; Psaty, Bruce M BM; Muzny, Donna D; Yu, Jin J; Gibbs, Richard A RA; Keinan, Alon A; Clark, Andrew G AG; Boerwinkle, Eric E

Publication Date: 2015

Variant appearance in text: rs72549326

PubMed Link: 25807536

Variant Present in the following documents:

• pone.0121644.s002.xls, sheet 1

View BVdb publication page

---

The Affymetrix DMET Plus platform reveals unique distribution of ADME-related variants in ethnic Arabs.

Disease Markers

Wakil, Salma M SM; Nguyen, Cao C; Muiya, Nzioka P NP; Andres, Editha E; Lykowska-Tarnowska, Agnieszka A; Baz, Batoul B; Tahir, Asma I AI; Meyer, Brian F BF; Morahan, Grant G; Dzimiri, Nduna N

Publication Date: 2015

Variant appearance in text: rs72549326

PubMed Link: 25802476

Variant Present in the following documents:

• 542543.f1.xlsx, sheet 1

View BVdb publication page

---

Clinical utility gene card for: Trimethylaminuria - update 2014.

European Journal Of Human Genetics : Ejhg

Shephard, Elizabeth A EA; Treacy, Eileen P EP; Phillips, Ian R IR

Publication Date: 2015-09

Variant appearance in text: FMO3: 458C>T; Pro153Leu

PubMed Link: 25335494

Variant Present in the following documents:

• Main text

View BVdb publication page

---

The RPTEC/TERT1 cell line models key renal cell responses to the environmental toxicants, benzo[a]pyrene and cadmium.

Toxicology Reports

Simon, B R BR; Wilson, M J MJ; Wickliffe, J K JK

Publication Date: 2014

Variant appearance in text: rs72549326

PubMed Link: 25126521

Variant Present in the following documents:

• mmc1.xls, sheet 1

View BVdb publication page

---

Integrated analysis of germline and somatic variants in ovarian cancer.

Nature Communications

Kanchi, Krishna L KL; Johnson, Kimberly J KJ; Lu, Charles C; McLellan, Michael D MD; Leiserson, Mark D M MD; Wendl, Michael C MC; Zhang, Qunyuan Q; Koboldt, Daniel C DC; Xie, Mingchao M; Kandoth, Cyriac C; McMichael, Joshua F JF; Wyczalkowski, Matthew A MA; Larson, David E DE; Schmidt, Heather K HK; Miller, Christopher A CA; Fulton, Robert S RS; Spellman, Paul T PT; Mardis, Elaine R ER; Druley, Todd E TE; Graubert, Timothy A TA; Goodfellow, Paul J PJ; Raphael, Benjamin J BJ; Wilson, Richard K RK; Ding, Li L

Publication Date: 2014

Variant appearance in text: FMO3: P153L

PubMed Link: 24448499

Variant Present in the following documents:

• NIHMS551112-supplement-9.xlsx, sheet 1

View BVdb publication page

---

Quail FMO3 gene cloning, tissue expression profiling, polymorphism detection and association analysis with fishy taint in eggs.

Plos One

Mo, Fengtao F; Zheng, Jiangxia J; Wang, Peng P; Lian, Ling L; Yi, Guoqiang G; Xu, Guiyun G; Yang, Ning N

Publication Date: 2013

Variant appearance in text: FMO3: P153L

PubMed Link: 24282592

Variant Present in the following documents:

• Main text
• pone.0081416.pdf

View BVdb publication page

---

The genetic landscape of high-risk neuroblastoma.

Nature Genetics

Pugh, Trevor J TJ; Morozova, Olena O; Attiyeh, Edward F EF; Asgharzadeh, Shahab S; Wei, Jun S JS; Auclair, Daniel D; Carter, Scott L SL; Cibulskis, Kristian K; Hanna, Megan M; Kiezun, Adam A; Kim, Jaegil J; Lawrence, Michael S MS; Lichenstein, Lee L; McKenna, Aaron A; Pedamallu, Chandra Sekhar CS; Ramos, Alex H AH; Shefler, Erica E; Sivachenko, Andrey A; Sougnez, Carrie C; Stewart, Chip C; Ally, Adrian A; Birol, Inanc I; Chiu, Readman R; Corbett, Richard D RD; Hirst, Martin M; Jackman, Shaun D SD; Kamoh, Baljit B; Khodabakshi, Alireza Hadj AH; Krzywinski, Martin M; Lo, Allan A; Moore, Richard A RA; Mungall, Karen L KL; Qian, Jenny J; Tam, Angela A; Thiessen, Nina N; Zhao, Yongjun Y; Cole, Kristina A KA; Diamond, Maura M; Diskin, Sharon J SJ; Mosse, Yael P YP; Wood, Andrew C AC; Ji, Lingyun L; Sposto, Richard R; Badgett, Thomas T; London, Wendy B WB; Moyer, Yvonne Y; Gastier-Foster, Julie M JM; Smith, Malcolm A MA; Guidry Auvil, Jaime M JM; Gerhard, Daniela S DS; Hogarty, Michael D MD; Jones, Steven J M SJ; Lander, Eric S ES; Gabriel, Stacey B SB; Getz, Gad G; Seeger, Robert C RC; Khan, Javed J; Marra, Marco A MA; Meyerson, Matthew M; Maris, John M JM

Publication Date: 2013-03

Variant appearance in text: FMO3: 458C>T; P153L; rs72549326

PubMed Link: 23334666

Variant Present in the following documents:

• NIHMS474900-supplement-8.xlsx, sheet 1
• NIHMS474900-supplement-8.xlsx, sheet 2

View BVdb publication page

---

Clinical utility gene card for: trimethylaminuria.

European Journal Of Human Genetics : Ejhg

Shephard, Elizabeth A EA; Treacy, Eileen P EP; Phillips, Ian R IR

Publication Date: 2012-03

Variant appearance in text: FMO3: Pro153Leu

PubMed Link: 22126753

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Trimethylaminuria: causes and diagnosis of a socially distressing condition.

The Clinical Biochemist. Reviews

Mackay, Richard J RJ; McEntyre, Christopher J CJ; Henderson, Caroline C; Lever, Michael M; George, Peter M PM

Publication Date: 2011-02

Variant appearance in text: FMO3: 458C>T; Pro153Leu

PubMed Link: 21451776

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Fish odour syndrome.

Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne

Li, Min M; Al-Sarraf, Ahmad A; Sinclair, Graham G; Frohlich, Jiri J

Publication Date: 2011-05-17

Variant appearance in text: FMO3: 458C>T; P153L

PubMed Link: 21422137

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Reaction phenotyping: current industry efforts to identify enzymes responsible for metabolizing drug candidates.

The Aaps Journal

Harper, Timothy W TW; Brassil, Patrick J PJ

Publication Date: 2008

Variant appearance in text: FMO3: P153L

PubMed Link: 18446520

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Revealing the moonlighting role of NADP in the structure of a flavin-containing monooxygenase.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Alfieri, Andrea A; Malito, Enrico E; Orru, Roberto R; Fraaije, Marco W MW; Mattevi, Andrea A

Publication Date: 2008-05-06

Variant appearance in text: FMO3: Pro153Leu

PubMed Link: 18443301

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Functional characterization of genetic variants of human FMO3 associated with trimethylaminuria.

Archives Of Biochemistry And Biophysics

Yeung, Catherine K CK; Adman, Elinor T ET; Rettie, Allan E AE

Publication Date: 2007-08-15

Variant appearance in text: FMO3: P153L

PubMed Link: 17531949

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Genetic polymorphisms of flavin monooxygenase 3 in sulindac-induced regression of colorectal adenomas in familial adenomatous polyposis.

Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology

Hisamuddin, Irfan M IM; Wehbi, Mohammad A MA; Schmotzer, Brian B; Easley, Kirk A KA; Hylind, Linda M LM; Giardiello, Francis M FM; Yang, Vincent W VW

Publication Date: 2005-10

Variant appearance in text: FMO3: P153L

PubMed Link: 16214918

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Mammalian flavin-containing monooxygenases: structure/function, genetic polymorphisms and role in drug metabolism.

Pharmacology & Therapeutics

Krueger, Sharon K SK; Williams, David E DE

Publication Date: 2005-06

Variant appearance in text: FMO3: P153L

PubMed Link: 15922018

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Benzydamine N-oxidation as an index reaction reflecting FMO activity in human liver microsomes and impact of FMO3 polymorphisms on enzyme activity.

British Journal Of Clinical Pharmacology

Störmer, E E; Roots, I I; Brockmöller, J J

Publication Date: 2000-12

Variant appearance in text: FMO3: P153L

PubMed Link: 11136294

Variant Present in the following documents:

• Main text

View BVdb publication page

---