Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.
Scientific Reports
Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases.
Cell Death & Disease
Grassi, Ludovica L; Alfonsi, Romina R; Francescangeli, Federica F; Signore, Michele M; De Angelis, Maria Laura ML; Addario, Antonio A; Costantini, Manuela M; Flex, Elisabetta E; Ciolfi, Andrea A; Pizzi, Simone S; Bruselles, Alessandro A; Pallocca, Matteo M; Simone, Giuseppe G; Haoui, Mustapha M; Falchi, Mario M; Milella, Michele M; Sentinelli, Steno S; Di Matteo, Paola P; Stellacci, Emilia E; Gallucci, Michele M; Muto, Giovanni G; Tartaglia, Marco M; De Maria, Ruggero R; Bonci, Désirée D
Publication Date: 2019-02-27
Variant appearance in text: MYOC: 730+35G>A; rs2032555
A likely pathogenic variant putatively affecting splicing of PIGA identified in a multiple congenital anomalies hypotonia-seizures syndrome 2 (MCAHS2) family pedigree via whole-exome sequencing.
Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells.
Stem Cell Reports
Garate, Zita Z; Quintana-Bustamante, Oscar O; Crane, Ana M AM; Olivier, Emmanuel E; Poirot, Laurent L; Galetto, Roman R; Kosinski, Penelope P; Hill, Collin C; Kung, Charles C; Agirre, Xabi X; Orman, Israel I; Cerrato, Laura L; Alberquilla, Omaira O; Rodriguez-Fornes, Fatima F; Fusaki, Noemi N; Garcia-Sanchez, Felix F; Maia, Tabita M TM; Ribeiro, Maria L ML; Sevilla, Julian J; Prosper, Felipe F; Jin, Shengfang S; Mountford, Joanne J; Guenechea, Guillermo G; Gouble, Agnes A; Bueren, Juan A JA; Davis, Brian R BR; Segovia, Jose C JC
Mutation spectrum of CYP1B1 and MYOC genes in Korean patients with primary congenital glaucoma.
Molecular Vision
Kim, Hee-Jung HJ; Suh, Wool W; Park, Sung Chul SC; Kim, Chan Yun CY; Park, Ki Ho KH; Kook, Michael S MS; Kim, Yong Yeon YY; Kim, Chang-Sik CS; Park, Chan Kee CK; Ki, Chang-Seok CS; Kee, Changwon C
Publication Date: 2011
Variant appearance in text: MYOC: 730+35G>A; rs2032555
Myocilin mutations in black South Africans with POAG.
Molecular Vision
Whigham, Benjamin T BT; Williams, Susan E I SE; Liu, Yutao Y; Rautenbach, Robyn M RM; Carmichael, Trevor R TR; Wheeler, Joshua J; Ziskind, Ari A; Qin, Xuejun X; Schmidt, Silke S; Ramsay, Michele M; Hauser, Michael A MA; Allingham, R Rand RR
Polymorphisms in an intronic region of the myocilin gene associated with primary open-angle glaucoma--a possible role for alternate splicing.
Molecular Vision
Pandaranayaka, P J Eswari PJ; Prasanthi, N N; Kannabiran, N N; Rangachari, K K; Dhivya, M M; Krishnadas, Subbiah R SR; Sundaresan, P P; Krishnaswamy, S S
Variable hearing impairment in a DFNB2 family with a novel MYO7A missense mutation.
Clinical Genetics
Hildebrand, M S MS; Thorne, N P NP; Bromhead, C J CJ; Kahrizi, K K; Webster, J A JA; Fattahi, Z Z; Bataejad, M M; Kimberling, W J WJ; Stephan, D D; Najmabadi, H H; Bahlo, M M; Smith, R J H RJ