PTGS2 c.*2427C>T

Variant ID: 1-186641058-G-A

NM_000963.2(PTGS2):c.*2427C>T

This variant was identified in 31 publications

View GRCh38 version.




Publications:


Genetic variant of cyclooxygenase-2 in gastric cancer: More inflammation and susceptibility.

World Journal Of Gastroenterology
Ji, Xuan-Ke XK; Madhurapantula, Sailaja Vatsalya SV; He, Gui G; Wang, Kun-Yan KY; Song, Chun-Hua CH; Zhang, Jian-Ying JY; Wang, Kai-Juan KJ
Publication Date: 2021-07-28

Variant appearance in text: rs689470
PubMed Link: 34366627
Variant Present in the following documents:
  • Main text
  • WJG-27-4653.pdf
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The effects of genotype on inflammatory response in hippocampal progenitor cells: A computational approach.

Brain, Behavior, & Immunity - Health
Lee, Hyunah H; Metz, Amelie A; McDiarmid, Amina A; Palmos, Alish A; Lee, Sang H SH; Curtis, Charles J CJ; Patel, Hamel H; Newhouse, Stephen J SJ; Thuret, Sandrine S
Publication Date: 2021-08

Variant appearance in text: rs689470
PubMed Link: 34345870
Variant Present in the following documents:
  • Main text
  • main.pdf
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Genetic Variants in COX2 and ALOX Genes and Breast Cancer Risk in White and Black Women.

Frontiers In Oncology
Mongiovi, Jennifer M JM; Hong, Chi-Chen CC; Zirpoli, Gary R GR; Khoury, Thaer T; Omilian, Angela R AR; Qin, Bo B; Bandera, Elisa V EV; Yao, Song S; Ambrosone, Christine B CB; Gong, Zhihong Z
Publication Date: 2021

Variant appearance in text: rs689470
PubMed Link: 34249719
Variant Present in the following documents:
  • Main text
  • fonc-11-679998.pdf
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A Scoping Review of Interactions between Omega-3 Long-Chain Polyunsaturated Fatty Acids and Genetic Variation in Relation to Cancer Risk.

Nutrients
Yurko-Mauro, Karin K; Van Elswyk, Mary M; Teo, Lynn L
Publication Date: 2020-06-02

Variant appearance in text: rs689470
PubMed Link: 32498320
Variant Present in the following documents:
  • Main text
  • nutrients-12-01647.pdf
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Next-Generation Sequencing of PTGS Genes Reveals an Increased Frequency of Non-synonymous Variants Among Patients With NSAID-Induced Liver Injury.

Frontiers In Genetics
Lucena, María Isabel MI; García-Martín, Elena E; Daly, Ann K AK; Blanca, Miguel M; Andrade, Raúl J RJ; Agúndez, José A G JAG
Publication Date: 2019

Variant appearance in text: rs689470
PubMed Link: 30873208
Variant Present in the following documents:
  • Main text
  • fgene-10-00134.pdf
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Whole genome sequencing identifies high-impact variants in well-known pharmacogenomic genes.

The Pharmacogenomics Journal
Choi, Jihoon J; Tantisira, Kelan G KG; Duan, Qing Ling QL
Publication Date: 2019-04

Variant appearance in text: rs689470
PubMed Link: 30214008
Variant Present in the following documents:
  • NIHMS1503453-supplement-3.xlsx, sheet 1
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Modulation of the prostaglandin-endoperoxide synthase 2 gene expression by variant haplotypes: influence of the 3'-untranslated region.

Brazilian Journal Of Medical And Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas
Piranda, D N DN; Abreu, R B V RBV; Freitas-Alves, D R DR; de Carvalho, M A MA; Vianna-Jorge, R R
Publication Date: 2017-11-30

Variant appearance in text: rs689470
PubMed Link: 29211250
Variant Present in the following documents:
  • Main text
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Variability of the drug response to nonsteroidal anti-inflammatory drugs according to cyclooxygenase-2 genetic polymorphism.

Drug Design, Development And Therapy
Lee, Sook Joung SJ; Park, Min Kyu MK; Shin, Dong-Seong DS; Chun, Min Ho MH
Publication Date: 2017

Variant appearance in text: rs689470
PubMed Link: 29066864
Variant Present in the following documents:
  • Main text
  • dddt-11-2727.pdf
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Single nucleotide polymorphisms as susceptibility, prognostic, and therapeutic markers of nonsmall cell lung cancer.

Lung Cancer (Auckland, N.Z.)
Zienolddiny, Shanbeh S; Skaug, Vidar V
Publication Date: 2012

Variant appearance in text: rs689470
PubMed Link: 28210120
Variant Present in the following documents:
  • Main text
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Prostaglandin-endoperoxide synthase 2 (PTGS2) rs20417 polymorphism and prostate cancer risk: a meta analysis.

International Journal Of Clinical And Experimental Medicine
Zhang, Lei L; Zhang, Yan Y; Zhang, Xu X; Hong, Baofa B
Publication Date: 2015

Variant appearance in text: rs689470
PubMed Link: 26884961
Variant Present in the following documents:
  • Main text
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Advances in dosimetry and biological predictors of radiation-induced esophagitis.

Oncotargets And Therapy
Yu, Yang Y; Guan, Hui H; Dong, Yuanli Y; Xing, Ligang L; Li, Xiaolin X
Publication Date: 2016

Variant appearance in text: rs689470
PubMed Link: 26869804
Variant Present in the following documents:
  • Main text
  • ott-9-597.pdf
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Adiposity, inflammation, genetic variants and risk of post-menopausal breast cancer findings from a prospective-specimen-collection, retrospective-blinded-evaluation (PRoBE) design approach.

Springerplus
Yan, Xiaowei Sherry XS; Barnholtz-Sloan, Jill J; Chu, Xin X; Li, Ling L; Colonie, Ryan R; Webster, Jessica J; Smelser, Diane D; Patel, Nikitaban N; Prichard, Jeffery J; Stark, Azadeh A
Publication Date: 2013

Variant appearance in text: rs689470
PubMed Link: 24340245
Variant Present in the following documents:
  • Main text
  • 40064_2013_Article_687.pdf
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Non-Steroidal Anti-Inflammatory Drugs, Variation in Inflammatory Genes, and Aggressive Prostate Cancer.

Pharmaceuticals (Basel, Switzerland)
Reese, Adam C AC; Hardin, Jill J; Cheng, Iona I; Casey, Graham G; Witte, John S JS
Publication Date: 2010-10-08

Variant appearance in text: rs689470
PubMed Link: 24023525
Variant Present in the following documents:
  • Main text
  • pharmaceuticals-03-03127.pdf
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Interactions between dietary n-3 fatty acids and genetic variants and risk of disease.

The British Journal Of Nutrition
Corella, Dolores D; Ordovás, José M JM
Publication Date: 2012-06

Variant appearance in text: rs689470
PubMed Link: 22591901
Variant Present in the following documents:
  • Main text
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No association of nineteen COX-2 gene variants to preclinical markers of atherosclerosis The Cardiovascular Risk in Young Finns Study.

Bmc Medical Genetics
Lähteelä, Kati K; Kunnas, Tarja T; Lyytikäinen, Leo-Pekka LP; Mononen, Nina N; Taittonen, Leena L; Laitinen, Tomi T; Kettunen, Johannes J; Juonala, Markus M; Hutri-Kähönen, Nina N; Kähönen, Mika M; Viikari, Jorma S JS; Raitakari, Olli T OT; Lehtimäki, Terho T; Nikkari, Seppo T ST
Publication Date: 2012-07-02

Variant appearance in text: rs689470
PubMed Link: 22551325
Variant Present in the following documents:
  • Main text
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Association between COX-2 rs2745557 polymorphism and prostate cancer risk: a systematic review and meta-analysis.

Bmc Immunology
Zhang, Hongtuan H; Xu, Yong Y; Zhang, Zhihong Z; Liu, Ranlu R; Ma, Baojie B
Publication Date: 2012-03-21

Variant appearance in text: rs689470
PubMed Link: 22435969
Variant Present in the following documents:
  • Main text
  • 1471-2172-13-14.pdf
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Prostate cancer and inflammation: the evidence.

Histopathology
Sfanos, Karen S KS; De Marzo, Angelo M AM
Publication Date: 2012-01

Variant appearance in text: rs689470
PubMed Link: 22212087
Variant Present in the following documents:
  • Main text
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Genetic variants associated with the risk of chronic obstructive pulmonary disease with and without lung cancer.

Cancer Prevention Research (Philadelphia, Pa.)
de Andrade, Mariza M; Li, Yan Y; Marks, Randolph S RS; Deschamps, Claude C; Scanlon, Paul D PD; Olswold, Curtis L CL; Jiang, Ruoxiang R; Swensen, Stephen J SJ; Sun, Zhifu Z; Cunningham, Julie M JM; Wampfler, Jason A JA; Limper, Andrew H AH; Midthun, David E DE; Yang, Ping P
Publication Date: 2012-03

Variant appearance in text: rs689470
PubMed Link: 22044695
Variant Present in the following documents:
  • Main text
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Candidate gene studies in gallbladder cancer: a systematic review and meta-analysis.

Mutation Research
Srivastava, Kshitij K; Srivastava, Anvesha A; Sharma, Kiran Lata KL; Mittal, Balraj B
Publication Date: 2011

Variant appearance in text: rs689470
PubMed Link: 21708280
Variant Present in the following documents:
  • Main text
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Interaction between use of non-steroidal anti-inflammatory drugs and selected genetic polymorphisms in ovarian cancer risk.

International Journal Of Molecular Epidemiology And Genetics
Pinheiro, Simone P SP; Gates, Margaret A MA; De Vivo, Immaculata I; Rosner, Bernard A BA; Tworoger, Shelley S SS; Titus-Ernstoff, Linda L; Hankinson, Susan E SE; Cramer, Daniel W DW
Publication Date: 2010-09-03

Variant appearance in text: rs689470
PubMed Link: 21532843
Variant Present in the following documents:
  • Main text
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PharmGKB summary: very important pharmacogene information for PTGS2.

Pharmacogenetics And Genomics
Thorn, Caroline F CF; Grosser, Tilo T; Klein, Teri E TE; Altman, Russ B RB
Publication Date: 2011-09

Variant appearance in text: rs689470
PubMed Link: 21063235
Variant Present in the following documents:
  • Main text
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Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer.

Plos One
Hildebrandt, Michelle A T MA; Komaki, Ritsuko R; Liao, Zhongxing Z; Gu, Jian J; Chang, Joe Y JY; Ye, Yuanqing Y; Lu, Charles C; Stewart, David J DJ; Minna, John D JD; Roth, Jack A JA; Lippman, Scott M SM; Cox, James D JD; Hong, Waun Ki WK; Spitz, Margaret R MR; Wu, Xifeng X
Publication Date: 2010-08-25

Variant appearance in text: rs689470
PubMed Link: 20811626
Variant Present in the following documents:
  • Main text
  • pone.0012402.pdf
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Use of aspirin and other nonsteroidal antiinflammatory medications in relation to prostate cancer risk.

American Journal Of Epidemiology
Salinas, Claudia A CA; Kwon, Erika M EM; FitzGerald, Liesel M LM; Feng, Ziding Z; Nelson, Peter S PS; Ostrander, Elaine A EA; Peters, Ulrike U; Stanford, Janet L JL
Publication Date: 2010-09-01

Variant appearance in text: rs689470
PubMed Link: 20688905
Variant Present in the following documents:
  • Main text
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Role of inflammation gene polymorphisms on pain severity in lung cancer patients.

Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Reyes-Gibby, Cielito C CC; Spitz, Margaret R MR; Yennurajalingam, Sriram S; Swartz, Michael M; Gu, Jian J; Wu, Xifeng X; Bruera, Eduardo E; Shete, Sanjay S
Publication Date: 2009-10

Variant appearance in text: rs689470
PubMed Link: 19773451
Variant Present in the following documents:
  • Main text
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Genetic variation in immune regulation and DNA repair pathways and stomach cancer in China.

Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Hussain, Shehnaz K SK; Mu, Li-Na LN; Cai, Lin L; Chang, Shen-Chih SC; Park, Sungshim Lani SL; Oh, Sam S SS; Wang, Yiren Y; Goldstein, Binh Y BY; Ding, Bao-Guo BG; Jiang, Qingwu Q; Rao, Jianyu J; You, Nai-Chieh Y NC; Yu, Shun-Zhang SZ; Papp, Jeanette C JC; Zhao, Jin-Kou JK; Wang, Hua H; Zhang, Zuo-Feng ZF
Publication Date: 2009-08

Variant appearance in text: rs689470
PubMed Link: 19661089
Variant Present in the following documents:
  • Main text
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Toll-like receptor signaling pathway variants and prostate cancer mortality.

Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Stark, Jennifer R JR; Wiklund, Fredrik F; Grönberg, Henrik H; Schumacher, Fredrick F; Sinnott, Jennifer A JA; Stampfer, Meir J MJ; Mucci, Lorelei A LA; Kraft, Peter P
Publication Date: 2009-06

Variant appearance in text: rs689470
PubMed Link: 19505919
Variant Present in the following documents:
  • Main text
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No association between cyclooxygenase-2 and uridine diphosphate glucuronosyltransferase 1A6 genetic polymorphisms and colon cancer risk.

World Journal Of Gastroenterology
Thompson, Cheryl-L CL; Plummer, Sarah-J SJ; Merkulova, Alona A; Cheng, Iona I; Tucker, Thomas-C TC; Casey, Graham G; Li, Li L
Publication Date: 2009-05-14

Variant appearance in text: rs689470
PubMed Link: 19437564
Variant Present in the following documents:
  • Main text
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Dietary omega-3 fatty acids, cyclooxygenase-2 genetic variation, and aggressive prostate cancer risk.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Fradet, Vincent V; Cheng, Iona I; Casey, Graham G; Witte, John S JS
Publication Date: 2009-04-01

Variant appearance in text: rs689470
PubMed Link: 19318492
Variant Present in the following documents:
  • Main text
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Cyclooxygenase-2 gene polymorphisms reduce the risk of oral premalignant lesions.

Cancer
Pu, Xia X; Lippman, Scott M SM; Yang, Hushan H; Lee, J Jack JJ; Wu, Xifeng X
Publication Date: 2009-04-01

Variant appearance in text: rs689470
PubMed Link: 19197984
Variant Present in the following documents:
  • Main text
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Protective effect of Cox-2 allelic variants on risk of colorectal adenoma development in African Americans.

Anticancer Research
Ashktorab, Hassan H; Tsang, Shirley S; Luke, Brian B; Sun, Zhonghe Z; Adam-Campbell, Lucile L; Kwagyan, John J; Poirier, Richard R; Akter, Shahina S; Akhgar, Ahmad A; Smoot, Duane D; Munroe, David J DJ; Ali, Iqbal Unnisa IU
Publication Date: 2008

Variant appearance in text: rs689470
PubMed Link: 19031967
Variant Present in the following documents:
  • Main text
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COX2 genetic variation, NSAIDs, and advanced prostate cancer risk.

British Journal Of Cancer
Cheng, I I; Liu, X X; Plummer, S J SJ; Krumroy, L M LM; Casey, G G; Witte, J S JS
Publication Date: 2007-08-20

Variant appearance in text: rs689470
PubMed Link: 17609663
Variant Present in the following documents:
  • Main text
  • 6603874a.pdf
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