A non-synonymous coding variant (L616F) in the TLR5 gene is potentially associated with Crohn's disease and influences responses to bacterial flagellin.
Plos One
Sheridan, Jared J; Mack, David R DR; Amre, Devendra K DK; Israel, David M DM; Cherkasov, Artem A; Li, Huifang H; Grimard, Guy G; Steiner, Theodore S TS
Association of inherited variation in Toll-like receptor genes with malignant melanoma susceptibility and survival.
Plos One
Gast, Andreas A; Bermejo, Justo Lorenzo JL; Claus, Rainer R; Brandt, Andreas A; Weires, Marianne M; Weber, Alexander A; Plass, Christoph C; Sucker, Antje A; Hemminki, Kari K; Schadendorf, Dirk D; Kumar, Rajiv R