PARP1 c.2285T>C ;(p.V762A)

Variant ID: 1-226555302-A-G

NM_001618.3(PARP1):c.2285T>C;(p.V762A)

This variant was identified in 235 publications

View GRCh38 version.




Publications:


The 3'UTR region of the DNA repair gene PARP-1 May increase the severity of COVID-19 by altering the binding of antiviral miRNAs.

Virology
Yılmaz, Büşra B; Çakmak Genç, Güneş G; Karakaş Çelik, Sevim S; Pişkin, Nihal N; Horuz, Emre E; Dursun, Ahmet A
Publication Date: 2023-04-18

Variant appearance in text: PARP: V762A; rs1136410
PubMed Link: 37087842
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Olaparib-Resistant BRCA2MUT Ovarian Cancer Cells with Restored BRCA2 Abrogate Olaparib-Induced DNA Damage and G2/M Arrest Controlled by the ATR/CHK1 Pathway for Survival.

Cells
Biegała, Łukasz Ł; Gajek, Arkadiusz A; Marczak, Agnieszka A; Rogalska, Aneta A
Publication Date: 2023-03-29

Variant appearance in text: PARP: V762A
PubMed Link: 37048111
Variant Present in the following documents:
  • Main text
  • cells-12-01038.pdf
View BVdb publication page



Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Publication Date: 2023-04-03

Variant appearance in text: PARP1: V762A
PubMed Link: 37012232
Variant Present in the following documents:
  • 41467_2023_37547_MOESM12_ESM.xlsx, sheet 3
  • 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2
View BVdb publication page



Clinical PARP inhibitors allosterically induce PARP2 retention on DNA.

Science Advances
Langelier, Marie-France MF; Lin, Xiaohui X; Zha, Shan S; Pascal, John M JM
Publication Date: 2023-03-24

Variant appearance in text: PARP: Val762Ala
PubMed Link: 36961901
Variant Present in the following documents:
  • sciadv.adf7175.pdf
View BVdb publication page



Bi-allelic mutation in SEC16B alters collagen trafficking and increases ER stress.

Embo Molecular Medicine
El-Gazzar, Ahmed A; Voraberger, Barbara B; Rauch, Frank F; Mairhofer, Mario M; Schmidt, Katy K; Guillemyn, Brecht B; Mitulović, Goran G; Reiterer, Veronika V; Haun, Margot M; Mayr, Michaela M MM; Mayr, Johannes A JA; Kimeswenger, Susanne S; Drews, Oliver O; Saraff, Vrinda V; Shaw, Nick N; Fratzl-Zelman, Nadja N; Symoens, Sofie S; Farhan, Hesso H; Högler, Wolfgang W
Publication Date: 2023-03-14

Variant appearance in text: PARP1: 2285T>C; Val762Ala
PubMed Link: 36916446
Variant Present in the following documents:
  • EMMM-15-e16834-s012.xlsx, sheet 1
View BVdb publication page



The relationship between single nucleotide polymorphisms and skin cancer susceptibility: A systematic review and network meta-analysis.

Frontiers In Oncology
Zhang, Lu L; Pozsgai, Éva É; Song, Yongan Y; Macharia, John J; Alfatafta, Huda H; Zheng, Jia J; Li, Zhaoyi Z; Liu, Hongbo H; Kiss, István I
Publication Date: 2023

Variant appearance in text: rs1136410
PubMed Link: 36874118
Variant Present in the following documents:
  • Main text
  • fonc-13-1094309.pdf
View BVdb publication page



Immunogenomic analysis of human brain metastases reveals diverse immune landscapes across genetically distinct tumors.

Cell Reports. Medicine
Álvarez-Prado, Ángel F ÁF; Maas, Roeltje R RR; Soukup, Klara K; Klemm, Florian F; Kornete, Mara M; Krebs, Fanny S FS; Zoete, Vincent V; Berezowska, Sabina S; Brouland, Jean-Philippe JP; Hottinger, Andreas F AF; Daniel, Roy T RT; Hegi, Monika E ME; Joyce, Johanna A JA
Publication Date: 2023-01-17

Variant appearance in text: PARP1: 2285T>C; Val762Ala
PubMed Link: 36652909
Variant Present in the following documents:
  • mmc8.xlsx, sheet 31
  • mmc3.xlsx, sheet 32
View BVdb publication page



Gene polymorphisms and prognosis of head and neck squamous cell carcinoma: a systematic review.

Reports Of Practical Oncology And Radiotherapy : Journal Of Greatpoland Cancer Center In Poznan And Polish Society Of Radiation Oncology
Rajabi-Moghaddam, Mahdieh M; Abbaszadeh, Hamid H
Publication Date: 2022

Variant appearance in text: rs1136410
PubMed Link: 36632296
Variant Present in the following documents:
  • rpor-27-6-1045.pdf
View BVdb publication page



Circulating messenger RNA variants as a potential biomarker for surveillance of hepatocellular carcinoma.

Frontiers In Oncology
Block, Timothy T; Zezulinski, Daniel D; Kaplan, David E DE; Lu, Jingqiao J; Zanine, Samantha S; Zhan, Tingting T; Doria, Cataldo C; Sayeed, Aejaz A
Publication Date: 2022

Variant appearance in text: rs1136410
PubMed Link: 36582804
Variant Present in the following documents:
  • Table_6.xlsx, sheet 1
View BVdb publication page



Common and rare variant associations with clonal haematopoiesis phenotypes.

Nature
Kessler, Michael D MD; Damask, Amy A; O'Keeffe, Sean S; Banerjee, Nilanjana N; Li, Dadong D; Watanabe, Kyoko K; Marketta, Anthony A; Van Meter, Michael M; Semrau, Stefan S; Horowitz, Julie J; Tang, Jing J; Kosmicki, Jack A JA; Rajagopal, Veera M VM; Zou, Yuxin Y; Houvras, Yariv Y; Ghosh, Arkopravo A; Gillies, Christopher C; Mbatchou, Joelle J; White, Ryan R RR; Verweij, Niek N; Bovijn, Jonas J; Parikshak, Neelroop N NN; LeBlanc, Michelle G MG; Jones, Marcus M; , ; , ; Glass, David J DJ; Lotta, Luca A LA; Cantor, Michael N MN; Atwal, Gurinder S GS; Locke, Adam E AE; Ferreira, Manuel A R MAR; Deering, Raquel R; Paulding, Charles C; Shuldiner, Alan R AR; Thurston, Gavin G; Ferrando, Adolfo A AA; Salerno, Will W; Reid, Jeffrey G JG; Overton, John D JD; Marchini, Jonathan J; Kang, Hyun M HM; Baras, Aris A; Abecasis, Gonçalo R GR; Jorgenson, Eric E
Publication Date: 2022-12

Variant appearance in text: PARP1: V762A; rs1136410
PubMed Link: 36450978
Variant Present in the following documents:
  • Main text
  • 41586_2022_Article_5448.pdf
View BVdb publication page



NAPRT, but Not NAMPT, Provides Additional Support for NAD Synthesis in Esophageal Precancerous Lesions.

Nutrients
Wang, Niannian N; Pan, Da D; Wang, Xuemei X; Su, Ming M; Wang, Xin X; Yan, Qingyang Q; Sun, Guiju G; Wang, Shaokang S
Publication Date: 2022-11-20

Variant appearance in text: PARP: Val762Ala; rs1136410
PubMed Link: 36432602
Variant Present in the following documents:
  • Main text
  • nutrients-14-04916.pdf
View BVdb publication page



Promotion of a synthetic degradation of activated STAT6 by PARP-1 inhibition: roles of poly(ADP-ribosyl)ation, calpains and autophagy.

Journal Of Translational Medicine
Wang, Jeffrey J; Ghonim, Mohamed A MA; Ibba, Salome V SV; Luu, Hanh H HH; Aydin, Yucel Y; Greer, Peter A PA; Boulares, A Hamid AH
Publication Date: 2022-11-08

Variant appearance in text: PARP: V762A
PubMed Link: 36348405
Variant Present in the following documents:
  • Main text
  • 12967_2022_Article_3715.pdf
View BVdb publication page



Molecular Epidemiology in Amerindians of the Brazilian Amazon Reveals New Genetic Variants in DNA Repair Genes.

Genes
Cohen-Paes, Amanda de Nazaré AN; de Alcântara, Angélica Leite AL; Moreira, Fabiano Cordeiro FC; Fernandes, Marianne Rodrigues MR; Pantoja, Karla Beatriz Cardias Cereja KBCC; Carvalho, Darlen Cardoso de DC; Guerreiro, João Farias JF; Ribeiro-Dos-Santos, Ândrea Â; Santos, Sidney Emanuel Batista Dos SEBD; Assumpção, Paulo Pimentel de PP; Santos, Ney Pereira Carneiro Dos NPCD
Publication Date: 2022-10-15

Variant appearance in text: rs1136410
PubMed Link: 36292754
Variant Present in the following documents:
  • genes-13-01869.pdf
View BVdb publication page



Beneficial effects of mifepristone treatment in breast cancer patients selected by the progesterone receptor isoform ratio: Results from the MIPRA trial.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Elía, Andrés A; Saldain, Leo L; Vanzulli, Silvia I SI; Helguero, Luisa A LA; Lamb, Caroline A CA; Fabris, Victoria V; Pataccini, Gabriela G; Martínez-Vazquez, Paula P; Burruchaga, Javier J; Caillet-Bois, Ines I; Spengler, Eunice E; Acosta Haab, Gabriela G; Liguori, Marcos M; Castets, Alejandra A; Lovisi, Silvia S; Abascal, María F MF; Novaro, Virginia V; Sánchez, Jana J; Muñoz, Javier J; Belizán, Jose M JM; Abba, Martín C MC; Gass, Hugo H; Rojas, Paola P; Lanari, Claudia C
Publication Date: 2022-10-21

Variant appearance in text: PARP1: 2285T>C; Val762Ala; rs1136410
PubMed Link: 36269797
Variant Present in the following documents:
  • ccr-22-2060_supplementary_table_s5_suppts5.xlsx, sheet 1
View BVdb publication page



Genetic susceptibility of bladder cancer in the Lebanese population.

Bmc Medical Genomics
Kourie, Hampig Raphael HR; Succar, Bahaa B; Chouery, Eliane E; Mehawej, Cybel C; Ahmadieh, Nizar N; Zouein, Joseph J; Mardirossian, Avedis A; Jalkh, Nadine N; Sleilaty, Ghassan G; Kattan, Joseph J; Nemr, Elie E
Publication Date: 2022-10-17

Variant appearance in text: PARP1: 2285T>C; Val762Ala; rs1136410
PubMed Link: 36253817
Variant Present in the following documents:
  • 12920_2022_1372_MOESM1_ESM.xlsx, sheet 1
  • 12920_2022_1372_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.

Scientific Reports
Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
Publication Date: 2022-10-14

Variant appearance in text: PARP1: V762A
PubMed Link: 36241656
Variant Present in the following documents:
  • 41598_2022_20939_MOESM10_ESM.xlsx, sheet 2
  • 41598_2022_20939_MOESM3_ESM.xlsx, sheet 2
  • 41598_2022_20939_MOESM11_ESM.xlsx, sheet 2
  • 41598_2022_20939_MOESM2_ESM.xlsx, sheet 2
View BVdb publication page



Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Nature Genetics
Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS
Publication Date: 2022-08

Variant appearance in text: PARP1: Val762Ala; rs1136410
PubMed Link: 35835912
Variant Present in the following documents:
  • Main text
  • 41588_2022_1121_MOESM2_ESM.pdf
  • 41588_2022_Article_1121.pdf
View BVdb publication page



Genomic, transcriptomic, and metabolomic profiles of hiPSC-derived dopamine neurons from clinically discordant brothers with identical PRKN deletions.

Npj Parkinson'S Disease
Cukier, Holly N HN; Kim, Hyunjin H; Griswold, Anthony J AJ; Codreanu, Simona G SG; Prince, Lisa M LM; Sherrod, Stacy D SD; McLean, John A JA; Dykxhoorn, Derek M DM; Ess, Kevin C KC; Hedera, Peter P; Bowman, Aaron B AB; Neely, M Diana MD
Publication Date: 2022-06-29

Variant appearance in text: PARP1: V762A; rs1136410
PubMed Link: 35768426
Variant Present in the following documents:
  • 41531_2022_346_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed.

Cell Genomics
Taub, Margaret A MA; Conomos, Matthew P MP; Keener, Rebecca R; Iyer, Kruthika R KR; Weinstock, Joshua S JS; Yanek, Lisa R LR; Lane, John J; Miller-Fleming, Tyne W TW; Brody, Jennifer A JA; Raffield, Laura M LM; McHugh, Caitlin P CP; Jain, Deepti D; Gogarten, Stephanie M SM; Laurie, Cecelia A CA; Keramati, Ali A; Arvanitis, Marios M; Smith, Albert V AV; Heavner, Benjamin B; Barwick, Lucas L; Becker, Lewis C LC; Bis, Joshua C JC; Blangero, John J; Bleecker, Eugene R ER; Burchard, Esteban G EG; Celedón, Juan C JC; Chang, Yen Pei C YPC; Custer, Brian B; Darbar, Dawood D; de Las Fuentes, Lisa L; DeMeo, Dawn L DL; Freedman, Barry I BI; Garrett, Melanie E ME; Gladwin, Mark T MT; Heckbert, Susan R SR; Hidalgo, Bertha A BA; Irvin, Marguerite R MR; Islam, Talat T; Johnson, W Craig WC; Kaab, Stefan S; Launer, Lenore L; Lee, Jiwon J; Liu, Simin S; Moscati, Arden A; North, Kari E KE; Peyser, Patricia A PA; Rafaels, Nicholas N; Seidman, Christine C; Weeks, Daniel E DE; Wen, Fayun F; Wheeler, Marsha M MM; Williams, L Keoki LK; Yang, Ivana V IV; Zhao, Wei W; Aslibekyan, Stella S; Auer, Paul L PL; Bowden, Donald W DW; Cade, Brian E BE; Chen, Zhanghua Z; Cho, Michael H MH; Cupples, L Adrienne LA; Curran, Joanne E JE; Daya, Michelle M; Deka, Ranjan R; Eng, Celeste C; Fingerlin, Tasha E TE; Guo, Xiuqing X; Hou, Lifang L; Hwang, Shih-Jen SJ; Johnsen, Jill M JM; Kenny, Eimear E EE; Levin, Albert M AM; Liu, Chunyu C; Minster, Ryan L RL; Naseri, Take T; Nouraie, Mehdi M; Reupena, Muagututi'a Sefuiva MS; Sabino, Ester C EC; Smith, Jennifer A JA; Smith, Nicholas L NL; Su, Jessica Lasky JL; Taylor, James G JG; Telen, Marilyn J MJ; Tiwari, Hemant K HK; Tracy, Russell P RP; White, Marquitta J MJ; Zhang, Yingze Y; Wiggins, Kerri L KL; Weiss, Scott T ST; Vasan, Ramachandran S RS; Taylor, Kent D KD; Sinner, Moritz F MF; Silverman, Edwin K EK; Shoemaker, M Benjamin MB; Sheu, Wayne H-H WH; Sciurba, Frank F; Schwartz, David A DA; Rotter, Jerome I JI; Roden, Daniel D; Redline, Susan S; Raby, Benjamin A BA; Psaty, Bruce M BM; Peralta, Juan M JM; Palmer, Nicholette D ND; Nekhai, Sergei S; Montgomery, Courtney G CG; Mitchell, Braxton D BD; Meyers, Deborah A DA; McGarvey, Stephen T ST; , ; Mak, Angel Cy AC; Loos, Ruth Jf RJ; Kumar, Rajesh R; Kooperberg, Charles C; Konkle, Barbara A BA; Kelly, Shannon S; Kardia, Sharon Lr SL; Kaplan, Robert R; He, Jiang J; Gui, Hongsheng H; Gilliland, Frank D FD; Gelb, Bruce D BD; Fornage, Myriam M; Ellinor, Patrick T PT; de Andrade, Mariza M; Correa, Adolfo A; Chen, Yii-Der Ida YI; Boerwinkle, Eric E; Barnes, Kathleen C KC; Ashley-Koch, Allison E AE; Arnett, Donna K DK; , ; , ; , ; Laurie, Cathy C CC; Abecasis, Goncalo G; Nickerson, Deborah A DA; Wilson, James G JG; Rich, Stephen S SS; Levy, Daniel D; Ruczinski, Ingo I; Aviv, Abraham A; Blackwell, Thomas W TW; Thornton, Timothy T; O'Connell, Jeff J; Cox, Nancy J NJ; Perry, James A JA; Armanios, Mary M; Battle, Alexis A; Pankratz, Nathan N; Reiner, Alexander P AP; Mathias, Rasika A RA
Publication Date: 2022-01-12

Variant appearance in text: rs1136410
PubMed Link: 35530816
Variant Present in the following documents:
  • Main text
  • mmc1.pdf
  • mmc2.pdf
  • main.pdf
View BVdb publication page



Associations between polymorphisms in genes of base excision repair pathway and lung cancer risk.

Translational Cancer Research
Liu, Shiqing S; Xiao, Yao Y; Hu, Chengping C; Li, Min M
Publication Date: 2020-04

Variant appearance in text: rs1136410
PubMed Link: 35117636
Variant Present in the following documents:
  • Main text
View BVdb publication page



Coronary Heart Disease in Type 2 Diabetes Mellitus: Genetic Factors and Their Mechanisms, Gene-Gene, and Gene-Environment Interactions in the Asian Populations.

International Journal Of Environmental Research And Public Health
Zarkasi, Khairul Anwar KA; Abdul Murad, Nor Azian NA; Ahmad, Norfazilah N; Jamal, Rahman R; Abdullah, Noraidatulakma N
Publication Date: 2022-01-06

Variant appearance in text: rs1136410
PubMed Link: 35055468
Variant Present in the following documents:
  • Main text
  • ijerph-19-00647.pdf
View BVdb publication page



Coronary Heart Disease in Type 2 Diabetes Mellitus: Genetic Factors and Their Mechanisms, Gene-Gene, and Gene-Environment Interactions in the Asian Populations.

International Journal Of Environmental Research And Public Health
Zarkasi, Khairul Anwar KA; Abdul Murad, Nor Azian NA; Ahmad, Norfazilah N; Jamal, Rahman R; Abdullah, Noraidatulakma N
Publication Date: 2022-01-06

Variant appearance in text: rs1136410
PubMed Link: 35055468
Variant Present in the following documents:
  • Main text
  • ijerph-19-00647.pdf
View BVdb publication page



SYNE1 Exonic Variant rs9479297 Contributes to Concurrent Hepatocellular and Transitional Cell Carcinoma Double Primary Cancer.

Biomedicines
Chu, Yu-De YD; Kee, Kwong-Ming KM; Lin, Wey-Ran WR; Lai, Ming-Wei MW; Lu, Sheng-Nan SN; Chung, Wen-Hung WH; Pang, See-Tong ST; Yeh, Chau-Ting CT
Publication Date: 2021-12-02

Variant appearance in text: PARP1: 2285T>C; V762A; rs1136410
PubMed Link: 34944636
Variant Present in the following documents:
  • Main text
  • biomedicines-09-01819.pdf
View BVdb publication page



SYNE1 Exonic Variant rs9479297 Contributes to Concurrent Hepatocellular and Transitional Cell Carcinoma Double Primary Cancer.

Biomedicines
Chu, Yu-De YD; Kee, Kwong-Ming KM; Lin, Wey-Ran WR; Lai, Ming-Wei MW; Lu, Sheng-Nan SN; Chung, Wen-Hung WH; Pang, See-Tong ST; Yeh, Chau-Ting CT
Publication Date: 2021-12-02

Variant appearance in text: PARP1: 2285T>C; V762A; rs1136410
PubMed Link: 34944636
Variant Present in the following documents:
  • Main text
  • biomedicines-09-01819.pdf
View BVdb publication page



Multiomics Landscape Uncovers the Molecular Mechanism of the Malignant Evolution of Lung Adenocarcinoma Cells to Chronic Low Dose Cadmium Exposure.

Frontiers In Oncology
Dai, Shun-Dong SD; Wang, Shuang S; Qin, Ya-Nan YN; Zhu, Jin-Chao JC
Publication Date: 2021

Variant appearance in text: PARP1: V762A
PubMed Link: 34858801
Variant Present in the following documents:
  • Table_1.xls, sheet 1
View BVdb publication page



High Poly(ADP-Ribose) Polymerase Expression Does Relate to Poor Survival in Solid Cancers: A Systematic Review and Meta-Analysis.

Cancers
Thakur, Nishant N; Yim, Kwangil K; Abdul-Ghafar, Jamshid J; Seo, Kyung Jin KJ; Chong, Yosep Y
Publication Date: 2021-11-09

Variant appearance in text: PARP: V762A
PubMed Link: 34830749
Variant Present in the following documents:
  • Main text
  • cancers-13-05594.pdf
View BVdb publication page



An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients.

Iscience
, ; Li, Jonathan J; Lim, Ryan G RG; Kaye, Julia A JA; Dardov, Victoria V; Coyne, Alyssa N AN; Wu, Jie J; Milani, Pamela P; Cheng, Andrew A; Thompson, Terri G TG; Ornelas, Loren L; Frank, Aaron A; Adam, Miriam M; Banuelos, Maria G MG; Casale, Malcolm M; Cox, Veerle V; Escalante-Chong, Renan R; Daigle, J Gavin JG; Gomez, Emilda E; Hayes, Lindsey L; Holewenski, Ronald R; Lei, Susan S; Lenail, Alex A; Lima, Leandro L; Mandefro, Berhan B; Matlock, Andrea A; Panther, Lindsay L; Patel-Murray, Natasha Leanna NL; Pham, Jacqueline J; Ramamoorthy, Divya D; Sachs, Karen K; Shelley, Brandon B; Stocksdale, Jennifer J; Trost, Hannah H; Wilhelm, Mark M; Venkatraman, Vidya V; Wassie, Brook T BT; Wyman, Stacia S; Yang, Stephanie S; , ; Van Eyk, Jennifer E JE; Lloyd, Thomas E TE; Finkbeiner, Steven S; Fraenkel, Ernest E; Rothstein, Jeffrey D JD; Sareen, Dhruv D; Svendsen, Clive N CN; Thompson, Leslie M LM
Publication Date: 2021-11-19

Variant appearance in text: PARP1: V762A
PubMed Link: 34746695
Variant Present in the following documents:
  • Main text
View BVdb publication page



Prioritizing natural-selection signals from the deep-sequencing genomic data suggests multi-variant adaptation in Tibetan highlanders.

National Science Review
Deng, Lian L; Zhang, Chao C; Yuan, Kai K; Gao, Yang Y; Pan, Yuwen Y; Ge, Xueling X; He, Yaoxi Y; Yuan, Yuan Y; Lu, Yan Y; Zhang, Xiaoxi X; Chen, Hao H; Lou, Haiyi H; Wang, Xiaoji X; Lu, Dongsheng D; Liu, Jiaojiao J; Tian, Lei L; Feng, Qidi Q; Khan, Asifullah A; Yang, Yajun Y; Jin, Zi-Bing ZB; Yang, Jian J; Lu, Fan F; Qu, Jia J; Kang, Longli L; Su, Bing B; Xu, Shuhua S
Publication Date: 2019-11

Variant appearance in text: PARP1: 2285T>C; Val762Ala; rs1136410
PubMed Link: 34691999
Variant Present in the following documents:
  • Main text
  • nwz108.pdf
View BVdb publication page



Genetic variants associated with platelet count are predictive of human disease and physiological markers.

Communications Biology
Mikaelsdottir, Evgenia E; Thorleifsson, Gudmar G; Stefansdottir, Lilja L; Halldorsson, Gisli G; Sigurdsson, Jon K JK; Lund, Sigrun H SH; Tragante, Vinicius V; Melsted, Pall P; Rognvaldsson, Solvi S; Norland, Kristjan K; Helgadottir, Anna A; Magnusson, Magnus K MK; Ragnarsson, Gunnar B GB; Kristinsson, Sigurdur Y SY; Reykdal, Sigrun S; Vidarsson, Brynjar B; Gudmundsdottir, Ingibjorg J IJ; Olafsson, Isleifur I; Onundarson, Pall T PT; Sigurdardottir, Olof O; Sigurdsson, Emil L EL; Grondal, Gerdur G; Geirsson, Arni J AJ; Geirsson, Gudmundur G; Gudmundsson, Julius J; Holm, Hilma H; Saevarsdottir, Saedis S; Jonsdottir, Ingileif I; Thorgeirsson, Gudmundur G; Gudbjartsson, Daniel F DF; Thorsteinsdottir, Unnur U; Rafnar, Thorunn T; Stefansson, Kari K
Publication Date: 2021-09-27

Variant appearance in text: PARP1: Val762Ala; rs1136410
PubMed Link: 34580418
Variant Present in the following documents:
  • 42003_2021_2642_MOESM4_ESM.xlsx, sheet 9
View BVdb publication page



The Role of Biofactors in Diabetic Microvascular Complications.

Current Diabetes Reviews
Ziegler, Dan D; Porta, Massimo M; Papanas, Nikolaos N; Mota, Maria M; Jermendy, György G; Beltramo, Elena E; Mazzeo, Aurora A; Caccioppo, Andrea A; Striglia, Elio E; Serhiyenko, Victoria V; Serhiyenko, Alexandr A; Rosta, László L; Stirban, Ovidiu Alin OA; Putz, Zsuzsanna Z; Istenes, Ildikó I; Horváth, Viktor V; Kempler, Peter P
Publication Date: 2022

Variant appearance in text: rs1136410
PubMed Link: 34433401
Variant Present in the following documents:
  • CDR-18-e250821195830.pdf
View BVdb publication page



T-2 Toxin Induces Oxidative Stress at Low Doses via Atf3ΔZip2a/2b-Mediated Ubiquitination and Degradation of Nrf2.

International Journal Of Molecular Sciences
Chen, Xiaoxuan X; Mu, Peiqiang P; Zhu, Lang L; Mao, Xiaoxiao X; Chen, Shuang S; Zhong, Huali H; Deng, Yiqun Y
Publication Date: 2021-07-25

Variant appearance in text: PARP1: Val762Ala
PubMed Link: 34360702
Variant Present in the following documents:
  • ijms-22-07936.pdf
View BVdb publication page



The effects of genetic polymorphisms on benzene-exposed workers: A systematic review.

Health Science Reports
Ramírez-Lopera, Verónica V; Uribe-Castro, Daniel D; Bautista-Amorocho, Henry H; Silva-Sayago, Jorge Alexander JA; Mateus-Sánchez, Enrique E; Ardila-Barbosa, Wilman Yesid WY; Pérez-Cala, Tania Liseth TL
Publication Date: 2021-09

Variant appearance in text: ADPRT: Val762Ala; rs1136410
PubMed Link: 34295994
Variant Present in the following documents:
  • Main text
  • HSR2-4-e327.pdf
View BVdb publication page



A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases.

Scientific Reports
Magraner-Pardo, Lorena L; Laskowski, Roman A RA; Pons, Tirso T; Thornton, Janet M JM
Publication Date: 2021-07-12

Variant appearance in text: rs1136410
PubMed Link: 34253785
Variant Present in the following documents:
  • 41598_2021_93715_MOESM3_ESM.xlsx, sheet 6
  • 41598_2021_93715_MOESM3_ESM.xlsx, sheet 5
View BVdb publication page



The lncRNA ANRIL Gene rs2151280 GG Genotype is Associated with Increased Susceptibility to Recurrent Miscarriage in a Southern Chinese Population.

Journal Of Inflammation Research
Che, Di D; Fang, Zhenzhen Z; Mai, Hanran H; Xu, Yufen Y; Fu, LanYan L; Zhou, Huazhong H; Zhang, Linyuan L; Pi, Lei L; Gu, Xiaoqiong X
Publication Date: 2021

Variant appearance in text: rs1136410
PubMed Link: 34234511
Variant Present in the following documents:
  • jir-14-2865.pdf
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Environmental Tobacco Smoke in Occupational Settings: Effect and Susceptibility Biomarkers in Workers From Lisbon Restaurants and Bars.

Frontiers In Public Health
Vital, Nádia N; Antunes, Susana S; Louro, Henriqueta H; Vaz, Fátima F; Simões, Tânia T; Penque, Deborah D; Silva, Maria João MJ
Publication Date: 2021

Variant appearance in text: ADPRT: V762A; rs1136410
PubMed Link: 34150711
Variant Present in the following documents:
  • Main text
  • fpubh-09-674142.pdf
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Genetic analysis of sinonasal undifferentiated carcinoma discovers recurrent SWI/SNF alterations and a novel PGAP3-SRPK1 fusion gene.

Bmc Cancer
Heft Neal, Molly E ME; Birkeland, Andrew C AC; Bhangale, Apurva D AD; Zhai, Jingyi J; Kulkarni, Aditi A; Foltin, Susan K SK; Jewell, Brittany M BM; Ludwig, Megan L ML; Pinatti, Lisa L; Jiang, Hui H; McHugh, Jonathan B JB; Marentette, Lawence L; McKean, Erin L EL; Brenner, J Chad JC
Publication Date: 2021-05-29

Variant appearance in text: PARP1: 2285T>C; Val762Ala; rs1136410
PubMed Link: 34051734
Variant Present in the following documents:
  • 12885_2021_8370_MOESM15_ESM.xlsx, sheet 1
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The PARP Enzyme Family and the Hallmarks of Cancer Part 2: Hallmarks Related to Cancer Host Interactions.

Cancers
Demény, Máté A MA; Virág, László L
Publication Date: 2021-04-24

Variant appearance in text: PARP: Val762Ala; rs1136410
PubMed Link: 33923319
Variant Present in the following documents:
  • Main text
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Systematic review and meta-analysis of genetic association studies of pelvic organ prolapse.

International Urogynecology Journal
Allen-Brady, Kristina K; Chua, John W F JWF; Cuffolo, Romana R; Koch, Marianne M; Sorrentino, Felice F; Cartwright, Rufus R
Publication Date: 2021-04-24

Variant appearance in text: rs1136410
PubMed Link: 33893823
Variant Present in the following documents:
  • Main text
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Disseminated Talaromyces marneffei Infection in a Non-HIV Infant With a Homozygous Private Variant of RELB.

Frontiers In Cellular And Infection Microbiology
Ding, Xiaofang X; Huang, Han H; Zhong, Lili L; Chen, Min M; Peng, Fang F; Zhang, Bing B; Cui, Xinyu X; Yang, Xiu-An XA
Publication Date: 2021

Variant appearance in text: PARP1: V762A; rs1136410
PubMed Link: 33791233
Variant Present in the following documents:
  • Table_2.xlsx, sheet 1
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Genetic variations in base excision repair pathway genes and risk of hepatoblastoma: a seven-center case-control study.

American Journal Of Cancer Research
Zhuo, Zhenjian Z; Lin, Ao A; Zhang, Jiao J; Chen, Huitong H; Li, Yong Y; Yang, Zhonghua Z; Li, Li L; Li, Suhong S; Cheng, Jiwen J; He, Jing J
Publication Date: 2021

Variant appearance in text: rs1136410
PubMed Link: 33791158
Variant Present in the following documents:
  • Main text
View BVdb publication page



Prioritization of candidate genes for a South African family with Parkinson's disease using in-silico tools.

Plos One
Sebate, Boiketlo B; Cuttler, Katelyn K; Cloete, Ruben R; Britz, Marcell M; Christoffels, Alan A; Williams, Monique M; Carr, Jonathan J; Bardien, Soraya S
Publication Date: 2021

Variant appearance in text: PARP1: 2285T>C; V762A; rs1136410
PubMed Link: 33770142
Variant Present in the following documents:
  • pone.0249324.s003.xlsx, sheet 1
  • pone.0249324.s003.xlsx, sheet 2
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PARP1 rs1136410 Val762Ala contributes to an increased risk of overall cancer in the East Asian population: a meta-analysis.

The Journal Of International Medical Research
Xin, Yijuan Y; Yang, Liu L; Su, Mingquan M; Cheng, Xiaoli X; Zhu, Lin L; Liu, Jiayun J
Publication Date: 2021-03

Variant appearance in text: PARP1: Val762Ala; rs1136410
PubMed Link: 33706586
Variant Present in the following documents:
  • Main text
  • 10.1177_0300060521992956.pdf
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Familial Colorectal Cancer and Genetic Susceptibility: Colorectal Risk Variants in First-Degree Relatives of Patients With Colorectal Cancer.

Clinical And Translational Gastroenterology
Gargallo-Puyuelo, Carla J CJ; Lanas, Ángel Á; Carrera-Lasfuentes, Patricia P; Ferrández, Ángel Á; Quintero, Enrique E; Carrillo, Marta M; Alonso-Abreu, Inmaculada I; García-González, María Asunción MA
Publication Date: 2021-02-03

Variant appearance in text: PARP1: V762A; rs1136410
PubMed Link: 33534415
Variant Present in the following documents:
  • Main text
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DNA Damage Response in Multiple Myeloma: The Role of the Tumor Microenvironment.

Cancers
Saitoh, Takayuki T; Oda, Tsukasa T
Publication Date: 2021-01-28

Variant appearance in text: PARP1: V762A
PubMed Link: 33525741
Variant Present in the following documents:
  • Main text
  • cancers-13-00504.pdf
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Dynamics of the HD regulatory subdomain of PARP-1; substrate access and allostery in PARP activation and inhibition.

Nucleic Acids Research
Ogden, Tom E H TEH; Yang, Ji-Chun JC; Schimpl, Marianne M; Easton, Laura E LE; Underwood, Elizabeth E; Rawlins, Philip B PB; McCauley, Michael M MM; Langelier, Marie-France MF; Pascal, John M JM; Embrey, Kevin J KJ; Neuhaus, David D
Publication Date: 2021-02-26

Variant appearance in text: PARP: V762A
PubMed Link: 33511412
Variant Present in the following documents:
  • Main text
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Patient-derived organoids in cellulosic sponge model chemotherapy response of metastatic colorectal cancer.

Clinical And Translational Medicine
Xu, Yanjie Y; Chen, Jianjun J; Huang, Yizhou Y; Luo, Yang Y; Hsieh, An-Chih AC; Chen, Jianyi J; Li, Han H; Wei, Xunbin X; Gao, Wei-Qiang WQ; Zhong, Ming M; Zhang, Yan Y
Publication Date: 2021-01

Variant appearance in text: PARP1: V762A; rs1136410
PubMed Link: 33463056
Variant Present in the following documents:
  • CTM2-11-e285-s003.xlsx, sheet 24
  • CTM2-11-e285-s003.xlsx, sheet 23
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Chemical Decorations of "MARs" Residents in Orchestrating Eukaryotic Gene Regulation.

Frontiers In Cell And Developmental Biology
Roychowdhury, Tanaya T; Chattopadhyay, Samit S
Publication Date: 2020

Variant appearance in text: PARP: Val762Ala
PubMed Link: 33409278
Variant Present in the following documents:
  • Main text
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Association of PARP1-specific polymorphisms and haplotypes with non-small cell lung cancer subtypes.

Plos One
Jin, Jing J; Robeson, Heather H; Fagan, Pebbles P; Orloff, Mohammed S MS
Publication Date: 2020

Variant appearance in text: PARP1: Val762Ala; rs1136410
PubMed Link: 33284833
Variant Present in the following documents:
  • Main text
  • pone.0243509.pdf
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