Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.
Scientific Reports
Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
Post-concussion symptoms and chronic pain after mild traumatic brain injury are modulated by multiple locus effect in the BDNF gene through the expression of antisense: A pilot prospective control study.
Canadian Journal Of Pain = Revue Canadienne De La Douleur
Khoury, Samar S; Segal, Julia J; Parisien, Marc M; Noreau, Anne A; Dion, Patrick P; Benavides, Rodrigo R; Giguère, Jean-François JF; Denis, Ronald R; Belfer, Inna I; Diatchenko, Luda L; Rouleau, Guy A GA; Lavigne, Gilles J GJ
Association of Melanoma-Risk Variants with Primary Melanoma Tumor Prognostic Characteristics and Melanoma-Specific Survival in the GEM Study.
Current Oncology (Toronto, Ont.)
Davari, Danielle R DR; Orlow, Irene I; Kanetsky, Peter A PA; Luo, Li L; Busam, Klaus J KJ; Sharma, Ajay A; Kricker, Anne A; Cust, Anne E AE; Anton-Culver, Hoda H; Gruber, Stephen B SB; Gallagher, Richard P RP; Zanetti, Roberto R; Rosso, Stefano S; Sacchetto, Lidia L; Dwyer, Terence T; Gibbs, David C DC; Ollila, David W DW; Begg, Colin B CB; Berwick, Marianne M; Thomas, Nancy E NE
Association of Melanoma-Risk Variants with Primary Melanoma Tumor Prognostic Characteristics and Melanoma-Specific Survival in the GEM Study.
Current Oncology (Toronto, Ont.)
Davari, Danielle R DR; Orlow, Irene I; Kanetsky, Peter A PA; Luo, Li L; Busam, Klaus J KJ; Sharma, Ajay A; Kricker, Anne A; Cust, Anne E AE; Anton-Culver, Hoda H; Gruber, Stephen B SB; Gallagher, Richard P RP; Zanetti, Roberto R; Rosso, Stefano S; Sacchetto, Lidia L; Dwyer, Terence T; Gibbs, David C DC; Ollila, David W DW; Begg, Colin B CB; Berwick, Marianne M; Thomas, Nancy E NE
Germline variants are associated with increased primary melanoma tumor thickness at diagnosis.
Human Molecular Genetics
Mangantig, Ernest E; MacGregor, Stuart S; Iles, Mark M MM; Scolyer, Richard A RA; Cust, Anne E AE; Hayward, Nicholas K NK; Montgomery, Grant W GW; Duffy, David L DL; Thompson, John F JF; Henders, Anjali A; Bowdler, Lisa L; Rowe, Casey C; Cadby, Gemma G; Mann, Graham J GJ; Whiteman, David C DC; Long, Georgina V GV; Ward, Sarah V SV; Khosrotehrani, Kiarash K; Barrett, Jennifer H JH; Law, Matthew H MH
Association of Known Melanoma Risk Factors with Primary Melanoma of the Scalp and Neck.
Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Wood, Renee P RP; Heyworth, Jane S JS; McCarthy, Nina S NS; Mauguen, Audrey A; Berwick, Marianne M; Thomas, Nancy E NE; Millward, Michael J MJ; Anton-Culver, Hoda H; Cust, Anne E AE; Dwyer, Terence T; Gallagher, Richard P RP; Gruber, Stephen B SB; Kanetsky, Peter A PA; Orlow, Irene I; Rosso, Stefano S; Moses, Eric K EK; Begg, Colin B CB; Ward, Sarah V SV
Inherited Melanoma Risk Variants Associated with Histopathologically Amelanotic Melanoma.
The Journal Of Investigative Dermatology
Gibbs, David Corley DC; Orlow, Irene I; Vernali, Steven S; Powell, Helen B HB; Kanetsky, Peter A PA; Luo, Li L; Busam, Klaus J KJ; Sharma, Ajay A; Kricker, Anne A; Armstrong, Bruce K BK; Cust, Anne E AE; Anton-Culver, Hoda H; Gruber, Stephen B SB; Gallagher, Richard P RP; Zanetti, Roberto R; Rosso, Stefano S; Sacchetto, Lidia L; Dwyer, Terence T; Ollila, David W DW; Begg, Colin B CB; Berwick, Marianne M; Thomas, Nancy E NE; ,
PARP1 rs1805407 Increases Sensitivity to PARP1 Inhibitors in Cancer Cells Suggesting an Improved Therapeutic Strategy.
Scientific Reports
Abecassis, Irina I; Sedgewick, Andrew J AJ; Romkes, Marjorie M; Buch, Shama S; Nukui, Tomoko T; Kapetanaki, Maria G MG; Vogt, Andreas A; Kirkwood, John M JM; Benos, Panayiotis V PV; Tawbi, Hussein H
Cell-type-specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes.
Genome Research
Zhang, Tongwu T; Choi, Jiyeon J; Kovacs, Michael A MA; Shi, Jianxin J; Xu, Mai M; , ; , ; Goldstein, Alisa M AM; Trower, Adam J AJ; Bishop, D Timothy DT; Iles, Mark M MM; Duffy, David L DL; MacGregor, Stuart S; Amundadottir, Laufey T LT; Law, Matthew H MH; Loftus, Stacie K SK; Pavan, William J WJ; Brown, Kevin M KM
Assessing the Incremental Contribution of Common Genomic Variants to Melanoma Risk Prediction in Two Population-Based Studies.
The Journal Of Investigative Dermatology
Cust, Anne E AE; Drummond, Martin M; Kanetsky, Peter A PA; , ; , ; Goldstein, Alisa M AM; Barrett, Jennifer H JH; MacGregor, Stuart S; Law, Matthew H MH; Iles, Mark M MM; Bui, Minh M; Hopper, John L JL; Brossard, Myriam M; Demenais, Florence F; Taylor, John C JC; Hoggart, Clive C; Brown, Kevin M KM; Landi, Maria Teresa MT; Newton-Bishop, Julia A JA; Mann, Graham J GJ; Bishop, D Timothy DT
Genetic Influences on Patient-Oriented Outcomes in Traumatic Brain Injury: A Living Systematic Review of Non-Apolipoprotein E Single-Nucleotide Polymorphisms.
Journal Of Neurotrauma
Zeiler, Frederick A FA; McFadyen, Charles C; Newcombe, Virginia F J VFJ; Synnot, Anneliese A; Donoghue, Emma L EL; Ripatti, Samuli S; Steyerberg, Ewout W EW; Gruen, Russel L RL; McAllister, Thomas W TW; Rosand, Jonathan J; Palotie, Aarno A; Maas, Andrew I R AIR; Menon, David K DK
Inherited Genetic Variants Associated with Melanoma BRAF/NRAS Subtypes.
The Journal Of Investigative Dermatology
Thomas, Nancy E NE; Edmiston, Sharon N SN; Orlow, Irene I; Kanetsky, Peter A PA; Luo, Li L; Gibbs, David C DC; Parrish, Eloise A EA; Hao, Honglin H; Busam, Klaus J KJ; Armstrong, Bruce K BK; Kricker, Anne A; Cust, Anne E AE; Anton-Culver, Hoda H; Gruber, Stephen B SB; Gallagher, Richard P RP; Zanetti, Roberto R; Rosso, Stefano S; Sacchetto, Lidia L; Dwyer, Terence T; Ollila, David W DW; Begg, Colin B CB; Berwick, Marianne M; Conway, Kathleen K; ,
Functional melanoma-risk variant IRF4 rs12203592 associated with Breslow thickness: a pooled international study of primary melanomas.
The British Journal Of Dermatology
Gibbs, D C DC; Ward, S V SV; Orlow, I I; Cadby, G G; Kanetsky, P A PA; Luo, L L; Busam, K J KJ; Kricker, A A; Armstrong, B K BK; Cust, A E AE; Anton-Culver, H H; Gallagher, R P RP; Zanetti, R R; Rosso, S S; Sacchetto, L L; Ollila, D W DW; Begg, C B CB; Berwick, M M; Thomas, N E NE; ,
Higher Nevus Count Exhibits a Distinct DNA Methylation Signature in Healthy Human Skin: Implications for Melanoma.
The Journal Of Investigative Dermatology
Roos, Leonie L; Sandling, Johanna K JK; Bell, Christopher G CG; Glass, Daniel D; Mangino, Massimo M; Spector, Tim D TD; Deloukas, Panos P; Bataille, Veronique V; Bell, Jordana T JT
Gene-environment interaction for polymorphisms in ataxia telangiectasia-mutated gene and radiation exposure in carcinogenesis: results from two literature-based meta-analyses of 27120 participants.
Oncotarget
Zhao, Yuguang Y; Yang, Lei L; Wu, Di D; He, Hua H; Wang, Mengmeng M; Ge, Tingwen T; Liu, Yudi Y; Tian, Huimin H; Cui, Jiuwei J; Jia, Lin L; Wan, Ziqiang Z; Han, Fujun F
Polymorphisms in DNA repair and oxidative stress genes associated with pre-treatment cognitive function in breast cancer survivors: an exploratory study.
Springerplus
Koleck, Theresa A TA; Bender, Catherine M CM; Sereika, Susan M SM; Brufsky, Adam M AM; Lembersky, Barry C BC; McAuliffe, Priscilla F PF; Puhalla, Shannon L SL; Rastogi, Priya P; Conley, Yvette P YP
Sex-specific genetic effects associated with pigmentation, sensitivity to sunlight, and melanoma in a population of Spanish origin.
Biology Of Sex Differences
Hernando, Barbara B; Ibarrola-Villava, Maider M; Fernandez, Lara P LP; Peña-Chilet, Maria M; Llorca-Cardeñosa, Marta M; Oltra, Sara S SS; Alonso, Santos S; Boyano, Maria Dolores MD; Martinez-Cadenas, Conrado C; Ribas, Gloria G
Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma.
Nature Genetics
Law, Matthew H MH; Bishop, D Timothy DT; Lee, Jeffrey E JE; Brossard, Myriam M; Martin, Nicholas G NG; Moses, Eric K EK; Song, Fengju F; Barrett, Jennifer H JH; Kumar, Rajiv R; Easton, Douglas F DF; Pharoah, Paul D P PDP; Swerdlow, Anthony J AJ; Kypreou, Katerina P KP; Taylor, John C JC; Harland, Mark M; Randerson-Moor, Juliette J; Akslen, Lars A LA; Andresen, Per A PA; Avril, Marie-Françoise MF; Azizi, Esther E; Scarrà, Giovanna Bianchi GB; Brown, Kevin M KM; Dębniak, Tadeusz T; Duffy, David L DL; Elder, David E DE; Fang, Shenying S; Friedman, Eitan E; Galan, Pilar P; Ghiorzo, Paola P; Gillanders, Elizabeth M EM; Goldstein, Alisa M AM; Gruis, Nelleke A NA; Hansson, Johan J; Helsing, Per P; Hočevar, Marko M; Höiom, Veronica V; Ingvar, Christian C; Kanetsky, Peter A PA; Chen, Wei V WV; , ; , ; , ; , ; , ; , ; Landi, Maria Teresa MT; Lang, Julie J; Lathrop, G Mark GM; Lubiński, Jan J; Mackie, Rona M RM; Mann, Graham J GJ; Molven, Anders A; Montgomery, Grant W GW; Novaković, Srdjan S; Olsson, Håkan H; Puig, Susana S; Puig-Butille, Joan Anton JA; Qureshi, Abrar A AA; Radford-Smith, Graham L GL; van der Stoep, Nienke N; van Doorn, Remco R; Whiteman, David C DC; Craig, Jamie E JE; Schadendorf, Dirk D; Simms, Lisa A LA; Burdon, Kathryn P KP; Nyholt, Dale R DR; Pooley, Karen A KA; Orr, Nick N; Stratigos, Alexander J AJ; Cust, Anne E AE; Ward, Sarah V SV; Hayward, Nicholas K NK; Han, Jiali J; Schulze, Hans-Joachim HJ; Dunning, Alison M AM; Bishop, Julia A Newton JAN; Demenais, Florence F; Amos, Christopher I CI; MacGregor, Stuart S; Iles, Mark M MM
Inherited genetic variants associated with occurrence of multiple primary melanoma.
Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Gibbs, David C DC; Orlow, Irene I; Kanetsky, Peter A PA; Luo, Li L; Kricker, Anne A; Armstrong, Bruce K BK; Anton-Culver, Hoda H; Gruber, Stephen B SB; Marrett, Loraine D LD; Gallagher, Richard P RP; Zanetti, Roberto R; Rosso, Stefano S; Dwyer, Terence T; Sharma, Ajay A; La Pilla, Emily E; From, Lynn L; Busam, Klaus J KJ; Cust, Anne E AE; Ollila, David W DW; Begg, Colin B CB; Berwick, Marianne M; Thomas, Nancy E NE; ,
A Web-based database of genetic association studies in cutaneous melanoma enhanced with network-driven data exploration tools.
Database : The Journal Of Biological Databases And Curation
Athanasiadis, Emmanouil I EI; Antonopoulou, Kyriaki K; Chatzinasiou, Foteini F; Lill, Christina M CM; Bourdakou, Marilena M MM; Sakellariou, Argiris A; Kypreou, Katerina K; Stefanaki, Irene I; Evangelou, Evangelos E; Ioannidis, John P A JP; Bertram, Lars L; Stratigos, Alexander J AJ; Spyrou, George M GM
Genetic factors associated with naevus count and dermoscopic patterns: preliminary results from the Study of Nevi in Children (SONIC).
The British Journal Of Dermatology
Orlow, I I; Satagopan, J M JM; Berwick, M M; Enriquez, H L HL; White, K A M KA; Cheung, K K; Dusza, S W SW; Oliveria, S A SA; Marchetti, M A MA; Scope, A A; Marghoob, A A AA; Halpern, A C AC
Fine mapping of genetic susceptibility loci for melanoma reveals a mixture of single variant and multiple variant regions.
International Journal Of Cancer
Barrett, Jennifer H JH; Taylor, John C JC; Bright, Chloe C; Harland, Mark M; Dunning, Alison M AM; Akslen, Lars A LA; Andresen, Per A PA; Avril, Marie-Françoise MF; Azizi, Esther E; Bianchi Scarrà, Giovanna G; Brossard, Myriam M; Brown, Kevin M KM; Dębniak, Tadeusz T; Elder, David E DE; Friedman, Eitan E; Ghiorzo, Paola P; Gillanders, Elizabeth M EM; Gruis, Nelleke A NA; Hansson, Johan J; Helsing, Per P; Hočevar, Marko M; Höiom, Veronica V; Ingvar, Christian C; Landi, Maria Teresa MT; Lang, Julie J; Lathrop, G Mark GM; Lubiński, Jan J; Mackie, Rona M RM; Molven, Anders A; Novaković, Srdjan S; Olsson, Håkan H; Puig, Susana S; Puig-Butille, Joan Anton JA; van der Stoep, Nienke N; van Doorn, Remco R; van Workum, Wilbert W; Goldstein, Alisa M AM; Kanetsky, Peter A PA; Pharoah, Paul D P PD; Demenais, Florence F; Hayward, Nicholas K NK; Newton Bishop, Julia A JA; Bishop, D Timothy DT; Iles, Mark M MM; ,
Identification of a melanoma susceptibility locus and somatic mutation in TET2.
Carcinogenesis
Song, Fengju F; Amos, Christopher I CI; Lee, Jeffrey E JE; Lian, Christine G CG; Fang, Shenying S; Liu, Hongliang H; MacGregor, Stuart S; Iles, Mark M MM; Law, Matthew H MH; Lindeman, Neal I NI; Montgomery, Grant W GW; Duffy, David L DL; Cust, Anne E AE; Jenkins, Mark A MA; Whiteman, David C DC; Kefford, Richard F RF; Giles, Graham G GG; Armstrong, Bruce K BK; Aitken, Joanne F JF; Hopper, John L JL; Brown, Kevin M KM; Martin, Nicholas G NG; Mann, Graham J GJ; Bishop, D Timothy DT; Bishop, Julia A Newton JA; , ; Kraft, Peter P; Qureshi, Abrar A AA; Kanetsky, Peter A PA; Hayward, Nicholas K NK; Hunter, David J DJ; Wei, Qingyi Q; Han, Jiali J
Variants associated with susceptibility to pancreatic cancer and melanoma do not reciprocally affect risk.
Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Wu, Lang L; Goldstein, Alisa M AM; Yu, Kai K; Yang, Xiaohong Rose XR; Rabe, Kari G KG; Arslan, Alan A AA; Canzian, Federico F; Wolpin, Brian M BM; Stolzenberg-Solomon, Rachael R; Amundadottir, Laufey T LT; Petersen, Gloria M GM
Genetic variants in PARP1 (rs3219090) and IRF4 (rs12203592) genes associated with melanoma susceptibility in a Spanish population.
Bmc Cancer
Peña-Chilet, Maria M; Blanquer-Maceiras, Maite M; Ibarrola-Villava, Maider M; Martinez-Cadenas, Conrado C; Martin-Gonzalez, Manuel M; Gomez-Fernandez, Cristina C; Mayor, Matias M; Aviles, Juan Antonio JA; Lluch, Ana A; Ribas, Gloria G
Genome-wide analysis of LXRα activation reveals new transcriptional networks in human atherosclerotic foam cells.
Nucleic Acids Research
Feldmann, Radmila R; Fischer, Cornelius C; Kodelja, Vitam V; Behrens, Sarah S; Haas, Stefan S; Vingron, Martin M; Timmermann, Bernd B; Geikowski, Anne A; Sauer, Sascha S
Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3.
Nature Genetics
Macgregor, Stuart S; Montgomery, Grant W GW; Liu, Jimmy Z JZ; Zhao, Zhen Zhen ZZ; Henders, Anjali K AK; Stark, Mitchell M; Schmid, Helen H; Holland, Elizabeth A EA; Duffy, David L DL; Zhang, Mingfeng M; Painter, Jodie N JN; Nyholt, Dale R DR; Maskiell, Judith A JA; Jetann, Jodie J; Ferguson, Megan M; Cust, Anne E AE; Jenkins, Mark A MA; Whiteman, David C DC; Olsson, Håkan H; Puig, Susana S; Bianchi-Scarrà, Giovanna G; Hansson, Johan J; Demenais, Florence F; Landi, Maria Teresa MT; Dębniak, Tadeusz T; Mackie, Rona R; Azizi, Esther E; Bressac-de Paillerets, Brigitte B; Goldstein, Alisa M AM; Kanetsky, Peter A PA; Gruis, Nelleke A NA; Elder, David E DE; Newton-Bishop, Julia A JA; Bishop, D Timothy DT; Iles, Mark M MM; Helsing, Per P; Amos, Christopher I CI; Wei, Qingyi Q; Wang, Li-E LE; Lee, Jeffrey E JE; Qureshi, Abrar A AA; Kefford, Richard F RF; Giles, Graham G GG; Armstrong, Bruce K BK; Aitken, Joanne F JF; Han, Jiali J; Hopper, John L JL; Trent, Jeffrey M JM; Brown, Kevin M KM; Martin, Nicholas G NG; Mann, Graham J GJ; Hayward, Nicholas K NK
Influence of PARP-1 polymorphisms in patients after traumatic brain injury.
Journal Of Neurotrauma
Sarnaik, Ajit A AA; Conley, Yvette P YP; Okonkwo, David O DO; Barr, Taura L TL; Fink, Ericka L EL; Szabo, Csaba C; Kochanek, Patrick M PM; Clark, Robert S B RS