Publications:

---

Is a PCSK9 Inhibitor Right for Your Patient? A Review of Treatment Data for Individualized Therapy.

International Journal Of Environmental Research And Public Health

Beltran, Roman A RA; Zemeir, Kyle J KJ; Kimberling, Chase R CR; Kneer, Mary S MS; Mifflin, Michelle D MD; Broderick, Tom L TL

Publication Date: 2022-12-16

Variant appearance in text: LDLC: I474V

PubMed Link: 36554779

Variant Present in the following documents:

• ijerph-19-16899.pdf

View BVdb publication page

---

Genetic Spectrum of Familial Hypercholesterolaemia in the Malaysian Community: Identification of Pathogenic Gene Variants Using Targeted Next-Generation Sequencing.

International Journal Of Molecular Sciences

Razman, Aimi Zafira AZ; Chua, Yung-An YA; Mohd Kasim, Noor Alicezah NA; Al-Khateeb, Alyaa A; Sheikh Abdul Kadir, Siti Hamimah SH; Jusoh, Siti Azma SA; Nawawi, Hapizah H; ,

Publication Date: 2022-11-29

Variant appearance in text: LDLC: I474V

PubMed Link: 36499307

Variant Present in the following documents:

• ijms-23-14971.pdf

View BVdb publication page

---

PCSK9: A Multi-Faceted Protein That Is Involved in Cardiovascular Biology.

Biomedicines

Sundararaman, Sai Sahana SS; Döring, Yvonne Y; van der Vorst, Emiel P C EPC

Publication Date: 2021-07-08

Variant appearance in text: LDLC: I474V

PubMed Link: 34356856

Variant Present in the following documents:

• Main text
• biomedicines-09-00793.pdf

View BVdb publication page

---

PCSK9 Variants in Familial Hypercholesterolemia: A Comprehensive Synopsis.

Frontiers In Genetics

Guo, Qianyun Q; Feng, Xunxun X; Zhou, Yujie Y

Publication Date: 2020

Variant appearance in text: LDLC: I474V

PubMed Link: 33173529

Variant Present in the following documents:

• fgene-11-01020.pdf

View BVdb publication page

---

PCSK9 Protein and rs562556 Polymorphism Are Associated With Arterial Plaques in Healthy Middle-Aged Population: The STANISLAS Cohort.

Journal Of The American Heart Association

Ferreira, João Pedro JP; Xhaard, Constance C; Lamiral, Zohra Z; Borges-Canha, Marta M; Neves, João Sérgio JS; Dandine-Roulland, Claire C; LeFloch, Edith E; Deleuze, Jean-François JF; Bacq-Daian, Delphine D; Bozec, Erwan E; Girerd, Nicolas N; Boivin, Jean-Marc JM; Zannad, Faiez F; Rossignol, Patrick P

Publication Date: 2020-04-07

Variant appearance in text: LDLC: I474V

PubMed Link: 32208829

Variant Present in the following documents:

• JAH3-9-e014758.pdf

View BVdb publication page

---

Differential effects of PCSK9 loss of function variants on serum lipid and PCSK9 levels in Caucasian and African Canadian populations.

Lipids In Health And Disease

Mayne, Janice J; Ooi, Teik Chye TC; Raymond, Angela A; Cousins, Marion M; Bernier, Lise L; Dewpura, Thilina T; Sirois, Francine F; Mbikay, Majambu M; Davignon, Jean J; Chrétien, Michel M

Publication Date: 2013-05-10

Variant appearance in text: LDLC: I474V

PubMed Link: 23663650

Variant Present in the following documents:

• Main text
• 1476-511X-12-70.pdf

View BVdb publication page

---

Mutation in the PCSK9 Gene in Omani Arab Subjects with Autosomal Dominant Hypercholesterolemia and its Effect on PCSK9 Protein Structure.

Oman Medical Journal

Al-Waili, Khalid K; Al-Zidi, Ward Al-Muna WA; Al-Abri, Abdul Rahim AR; Al-Rasadi, Khalid K; Al-Sabti, Hilal Ali HA; Shah, Karna K; Al-Futaisi, Abdullah A; Al-Zakwani, Ibrahim I; Banerjee, Yajnavalka Y

Publication Date: 2013-01

Variant appearance in text: LDLC: Ile474Val

PubMed Link: 23386946

Variant Present in the following documents:

• Main text

View BVdb publication page

---