Variant ID: 1-40028180-A-G

NM_001135653.1(PABPC4):c.1669-92T>C

This variant was identified in 93 publications




Publications:


Genetic determinants of blood lipids and cerebral small vessel disease: role of high-density lipoprotein cholesterol.

Brain : A Journal Of Neurology
MK Georgakis, R Malik, CD Anderson, KG Parhofer, JC Hopewell, M Dichgans
Publication Date: 2020-02-01

Variant appearance in text: rs4660293
PubMed Link: 31968102
PubMed Central Link
Variant Present in the following documents:
  • Main text
  • Supplemental file
View BVdb publication page



A Mendelian Randomization Study Provides Evidence That Adiposity and Dyslipidemia Lead to Lower Urinary Albumin-to-Creatinine Ratio, a Marker of Microvascular Function.

Diabetes
F Casanova, AR Wood, H Yaghootkar, RN Beaumont, SE Jones, KM Gooding, K Aizawa, WD Strain, AT Hattersley, F Khan, AC Shore, TM Frayling, J Tyrrell
Publication Date: 2020-05

Variant appearance in text: rs4660293
PubMed Link: 31915152
PubMed Central Link
Variant Present in the following documents:
  • Supplemental file
View BVdb publication page



Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration.

Nature Communications
R Noordam, MM Bos, H Wang, TW Winkler, AR Bentley, TO Kilpeläinen, PS de Vries, YJ Sung, K Schwander, BE Cade, A Manning, H Aschard, MR Brown, H Chen, N Franceschini, SK Musani, M Richard, D Vojinovic, S Aslibekyan, TM Bartz, L de Las Fuentes, M Feitosa, AR Horimoto, M Ilkov, M Kho, A Kraja, C Li, E Lim, Y Liu, DO Mook-Kanamori, T Rankinen, SM Tajuddin, A van der Spek, Z Wang, J Marten, V Laville, M Alver, E Evangelou, ME Graff, M He, B Kühnel, LP Lyytikäinen, P Marques-Vidal, IM Nolte, ND Palmer, R Rauramaa, XO Shu, H Snieder, S Weiss, W Wen, LR Yanek, C Adolfo, C Ballantyne, L Bielak, NR Biermasz, E Boerwinkle, N Dimou, G Eiriksdottir, C Gao, SA Gharib, DJ Gottlieb, J Haba-Rubio, TB Harris, S Heikkinen, R Heinzer, JE Hixson, G Homuth, MA Ikram, P Komulainen, JE Krieger, J Lee, J Liu, KK Lohman, AI Luik, R Mägi, LW Martin, T Meitinger, A Metspalu, Y Milaneschi, MA Nalls, J O'Connell, A Peters, P Peyser, OT Raitakari, AP Reiner, PCN Rensen, TK Rice, SS Rich, T Roenneberg, JI Rotter, PJ Schreiner, J Shikany, SS Sidney, M Sims, CM Sitlani, T Sofer, K Strauch, MA Swertz, KD Taylor, AG Uitterlinden, CM van Duijn, H Völzke, M Waldenberger, RB Wallance, KW van Dijk, C Yu, AB Zonderman, DM Becker, P Elliott, T Esko, C Gieger, HJ Grabe, TA Lakka, T Lehtimäki, KE North, BWJH Penninx, P Vollenweider, LE Wagenknecht, T Wu, YB Xiang, W Zheng, DK Arnett, C Bouchard, MK Evans, V Gudnason, S Kardia, TN Kelly, SB Kritchevsky, RJF Loos, AC Pereira, M Province, BM Psaty, C Rotimi, X Zhu, N Amin, LA Cupples, M Fornage, EF Fox, X Guo, WJ Gauderman, K Rice, C Kooperberg, PB Munroe, CT Liu, AC Morrison, DC Rao, D van Heemst, S Redline
Publication Date: 2019-11-12

Variant appearance in text: rs4660293
PubMed Link: 31719535
PubMed Central Link
Variant Present in the following documents:
  • 41467_2019_12958_MOESM7_ESM.xlsx
View BVdb publication page



Bayesian multivariate reanalysis of large genetic studies identifies many new associations.

Plos Genetics
MC Turchin, M Stephens
Publication Date: 2019-10

Variant appearance in text: rs4660293
PubMed Link: 31596850
PubMed Central Link
Variant Present in the following documents:
  • pgen.1008431.s007.xls
  • pgen.1008431.s006.xls
View BVdb publication page



Genetic architecture of human plasma lipidome and its link to cardiovascular disease.

Nature Communications
R Tabassum, JT Rämö, P Ripatti, JT Koskela, M Kurki, J Karjalainen, P Palta, S Hassan, J Nunez-Fontarnau, TTJ Kiiskinen, S Söderlund, N Matikainen, MJ Gerl, MA Surma, C Klose, NO Stitziel, H Laivuori, AS Havulinna, SK Service, V Salomaa, M Pirinen, , M Jauhiainen, MJ Daly, NB Freimer, A Palotie, MR Taskinen, K Simons, S Ripatti
Publication Date: 2019-09-24

Variant appearance in text: rs4660293
PubMed Link: 31551469
PubMed Central Link
Variant Present in the following documents:
  • 41467_2019_11954_MOESM13_ESM.xlsx
  • 41467_2019_11954_MOESM14_ESM.xlsx
View BVdb publication page



The transferability of lipid loci across African, Asian and European cohorts.

Nature Communications
K Kuchenbaecker, N Telkar, T Reiker, RG Walters, K Lin, A Eriksson, D Gurdasani, A Gilly, L Southam, E Tsafantakis, M Karaleftheri, J Seeley, A Kamali, G Asiki, IY Millwood, M Holmes, H Du, Y Guo, M Kumari, G Dedoussis, L Li, Z Chen, MS Sandhu, E Zeggini,
Publication Date: 2019-09-24

Variant appearance in text: rs4660293
PubMed Link: 31551420
PubMed Central Link
Variant Present in the following documents:
  • 41467_2019_12026_MOESM1_ESM.pdf
View BVdb publication page



Mendelian randomization analysis rules out disylipidaemia as colorectal cancer cause.

Scientific Reports
G Ibáñez-Sanz, A Díez-Villanueva, M Riera-Ponsati, T Fernández-Villa, P Fernández Navarro, M Bustamante, J Llorca, P Amiano, N Ascunce, G Fernández-Tardón, I Salcedo Bellido, D Salas, R Capelo Álvarez, M Crous-Bou, L Ortega-Valín, B Pérez-Gómez, G Castaño-Vinyals, C Palazuelos, JM Altzibar, E Ardanaz, A Tardón, JJ Jiménez Moleón, V Olmos Juste, N Aragonés, M Pollán, M Kogevinas, V Moreno
Publication Date: 2019-09-16

Variant appearance in text: rs4660293
PubMed Link: 31527690
PubMed Central Link
Variant Present in the following documents:
  • 41598_2019_49880_MOESM1_ESM.doc
View BVdb publication page



Integrative analysis of vascular endothelial cell genomic features identifies AIDA as a coronary artery disease candidate gene.

Genome Biology
S Lalonde, VA Codina-Fauteux, SM de Bellefon, F Leblanc, M Beaudoin, MM Simon, R Dali, T Kwan, KS Lo, T Pastinen, G Lettre
Publication Date: 2019-07-08

Variant appearance in text: rs4660293
PubMed Link: 31287004
PubMed Central Link
Variant Present in the following documents:
  • 13059_2019_1749_MOESM11_ESM.xlsx
View BVdb publication page



Discovery of Allele-Specific Protein-RNA Interactions in Human Transcriptomes.

American Journal Of Human Genetics
E Bahrami-Samani, Y Xing
Publication Date: 2019-03-07

Variant appearance in text: rs4660293
PubMed Link: 30827501
PubMed Central Link
Variant Present in the following documents:
  • mmc7.xlsx
View BVdb publication page



Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations.

Nature Genetics
P Sakornsakolpat, D Prokopenko, M Lamontagne, NF Reeve, AL Guyatt, VE Jackson, N Shrine, D Qiao, TM Bartz, DK Kim, MK Lee, JC Latourelle, X Li, JD Morrow, M Obeidat, AB Wyss, P Bakke, RG Barr, TH Beaty, SA Belinsky, GG Brusselle, JD Crapo, K de Jong, DL DeMeo, TE Fingerlin, SA Gharib, A Gulsvik, IP Hall, JE Hokanson, WJ Kim, DA Lomas, SJ London, DA Meyers, GT O'Connor, SI Rennard, DA Schwartz, P Sliwinski, D Sparrow, DP Strachan, R Tal-Singer, Y Tesfaigzi, J Vestbo, JM Vonk, JJ Yim, X Zhou, Y Bossé, A Manichaikul, L Lahousse, EK Silverman, HM Boezen, LV Wain, MD Tobin, BD Hobbs, MH Cho, ,
Publication Date: 2019-03

Variant appearance in text: rs4660293
PubMed Link: 30804561
PubMed Central Link
Variant Present in the following documents:
  • NIHMS1517255-supplement-Sup_Tables.xlsx
View BVdb publication page



Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.

Nature Communications
TO Kilpeläinen, AR Bentley, R Noordam, YJ Sung, K Schwander, TW Winkler, H Jakupović, DI Chasman, A Manning, I Ntalla, H Aschard, MR Brown, L de Las Fuentes, N Franceschini, X Guo, D Vojinovic, S Aslibekyan, MF Feitosa, M Kho, SK Musani, M Richard, H Wang, Z Wang, TM Bartz, LF Bielak, A Campbell, R Dorajoo, V Fisher, FP Hartwig, ARVR Horimoto, C Li, KK Lohman, J Marten, X Sim, AV Smith, SM Tajuddin, M Alver, M Amini, M Boissel, JF Chai, X Chen, J Divers, E Evangelou, C Gao, M Graff, SE Harris, M He, FC Hsu, AU Jackson, JH Zhao, AT Kraja, B Kühnel, F Laguzzi, LP Lyytikäinen, IM Nolte, R Rauramaa, M Riaz, A Robino, R Rueedi, HM Stringham, F Takeuchi, PJ van der Most, TV Varga, N Verweij, EB Ware, W Wen, X Li, LR Yanek, N Amin, DK Arnett, E Boerwinkle, M Brumat, B Cade, M Canouil, YI Chen, MP Concas, J Connell, R de Mutsert, HJ de Silva, PS de Vries, A Demirkan, J Ding, CB Eaton, JD Faul, Y Friedlander, KP Gabriel, M Ghanbari, F Giulianini, CC Gu, D Gu, TB Harris, J He, S Heikkinen, CK Heng, SC Hunt, MA Ikram, JB Jonas, WP Koh, P Komulainen, JE Krieger, SB Kritchevsky, Z Kutalik, J Kuusisto, CD Langefeld, C Langenberg, LJ Launer, K Leander, RN Lemaitre, CE Lewis, J Liang, , J Liu, R Mägi, A Manichaikul, T Meitinger, A Metspalu, Y Milaneschi, KL Mohlke, TH Mosley, AD Murray, MA Nalls, EK Nang, CP Nelson, S Nona, JM Norris, CV Nwuba, J O'Connell, ND Palmer, GJ Papanicolau, R Pazoki, NL Pedersen, A Peters, PA Peyser, O Polasek, DJ Porteous, A Poveda, OT Raitakari, SS Rich, N Risch, JG Robinson, LM Rose, I Rudan, PJ Schreiner, RA Scott, SS Sidney, M Sims, JA Smith, H Snieder, T Sofer, JM Starr, B Sternfeld, K Strauch, H Tang, KD Taylor, MY Tsai, J Tuomilehto, AG Uitterlinden, MY van der Ende, D van Heemst, T Voortman, M Waldenberger, P Wennberg, G Wilson, YB Xiang, J Yao, C Yu, JM Yuan, W Zhao, AB Zonderman, DM Becker, M Boehnke, DW Bowden, U de Faire, IJ Deary, P Elliott, T Esko, BI Freedman, P Froguel, P Gasparini, C Gieger, N Kato, M Laakso, TA Lakka, T Lehtimäki, PKE Magnusson, AJ Oldehinkel, BWJH Penninx, NJ Samani, XO Shu, P van der Harst, JV Van Vliet-Ostaptchouk, P Vollenweider, LE Wagenknecht, YX Wang, NJ Wareham, DR Weir, T Wu, W Zheng, X Zhu, MK Evans, PW Franks, V Gudnason, C Hayward, BL Horta, TN Kelly, Y Liu, KE North, AC Pereira, PM Ridker, ES Tai, RM van Dam, ER Fox, SLR Kardia, CT Liu, DO Mook-Kanamori, MA Province, S Redline, CM van Duijn, JI Rotter, CB Kooperberg, WJ Gauderman, BM Psaty, K Rice, PB Munroe, M Fornage, LA Cupples, CN Rotimi, AC Morrison, DC Rao, RJF Loos
Publication Date: 2019-01-22

Variant appearance in text: rs4660293
PubMed Link: 30670697
PubMed Central Link
Variant Present in the following documents:
  • 41467_2018_8008_MOESM7_ESM.xlsx
  • 41467_2018_8008_MOESM10_ESM.xlsx
View BVdb publication page



Type 2 Diabetes and Hypertension.

Circulation Research
D Sun, T Zhou, Y Heianza, X Li, M Fan, VA Fonseca, L Qi
Publication Date: 2019-03-15

Variant appearance in text: rs4660293
PubMed Link: 30646822
PubMed Central Link
Variant Present in the following documents:
  • Main text
View BVdb publication page



Gene-Based Elevated Triglycerides and Type 2 Diabetes Mellitus Risk in the Women's Genome Health Study.

Arteriosclerosis, Thrombosis, And Vascular Biology
S Ahmad, S Mora, PM Ridker, FB Hu, DI Chasman
Publication Date: 2019-01

Variant appearance in text: rs4660293
PubMed Link: 30565958
PubMed Central Link
Variant Present in the following documents:
  • NIHMS1512616-supplement-Supplemental_Material.pdf
View BVdb publication page



Genome-wide association meta-analysis yields 20 loci associated with gallstone disease.

Nature Communications
E Ferkingstad, A Oddsson, S Gretarsdottir, S Benonisdottir, G Thorleifsson, AM Deaton, S Jonsson, OA Stefansson, GL Norddahl, F Zink, GA Arnadottir, B Gunnarsson, GH Halldorsson, A Helgadottir, BO Jensson, RP Kristjansson, G Sveinbjornsson, DA Sverrisson, G Masson, I Olafsson, GI Eyjolfsson, O Sigurdardottir, H Holm, I Jonsdottir, S Olafsson, T Steingrimsdottir, T Rafnar, ES Bjornsson, U Thorsteinsdottir, DF Gudbjartsson, P Sulem, K Stefansson
Publication Date: 2018-11-30

Variant appearance in text: rs4660293
PubMed Link: 30504769
PubMed Central Link
Variant Present in the following documents:
  • 41467_2018_7460_MOESM12_ESM.xlsx
View BVdb publication page



Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.

American Journal Of Human Genetics
S Ligthart, A Vaez, U Võsa, MG Stathopoulou, PS de Vries, BP Prins, PJ Van der Most, T Tanaka, E Naderi, LM Rose, Y Wu, R Karlsson, M Barbalic, H Lin, R Pool, G Zhu, A Macé, C Sidore, S Trompet, M Mangino, M Sabater-Lleal, JP Kemp, A Abbasi, T Kacprowski, N Verweij, AV Smith, T Huang, C Marzi, MF Feitosa, KK Lohman, ME Kleber, Y Milaneschi, C Mueller, M Huq, E Vlachopoulou, LP Lyytikäinen, C Oldmeadow, J Deelen, M Perola, JH Zhao, B Feenstra, , M Amini, , J Lahti, KE Schraut, M Fornage, B Suktitipat, WM Chen, X Li, T Nutile, G Malerba, J Luan, T Bak, N Schork, F Del Greco M, E Thiering, A Mahajan, RE Marioni, E Mihailov, J Eriksson, AB Ozel, W Zhang, M Nethander, YC Cheng, S Aslibekyan, W Ang, I Gandin, L Yengo, L Portas, C Kooperberg, E Hofer, KB Rajan, C Schurmann, W den Hollander, TS Ahluwalia, J Zhao, HHM Draisma, I Ford, N Timpson, A Teumer, H Huang, S Wahl, Y Liu, J Huang, HW Uh, F Geller, PK Joshi, LR Yanek, E Trabetti, B Lehne, D Vozzi, M Verbanck, G Biino, Y Saba, I Meulenbelt, JR O'Connell, M Laakso, F Giulianini, PKE Magnusson, CM Ballantyne, JJ Hottenga, GW Montgomery, F Rivadineira, R Rueedi, M Steri, KH Herzig, DJ Stott, C Menni, M Frånberg, B St Pourcain, SB Felix, TH Pers, SJL Bakker, P Kraft, A Peters, D Vaidya, G Delgado, JH Smit, V Großmann, J Sinisalo, I Seppälä, SR Williams, EG Holliday, M Moed, C Langenberg, K Räikkönen, J Ding, H Campbell, MM Sale, YI Chen, AL James, D Ruggiero, N Soranzo, CA Hartman, EN Smith, GS Berenson, C Fuchsberger, D Hernandez, CMT Tiesler, V Giedraitis, D Liewald, K Fischer, D Mellström, A Larsson, Y Wang, WR Scott, M Lorentzon, J Beilby, KA Ryan, CE Pennell, D Vuckovic, B Balkau, MP Concas, R Schmidt, CF Mendes de Leon, EP Bottinger, M Kloppenburg, L Paternoster, M Boehnke, AW Musk, G Willemsen, DM Evans, PAF Madden, M Kähönen, Z Kutalik, M Zoledziewska, V Karhunen, SB Kritchevsky, N Sattar, G Lachance, R Clarke, TB Harris, OT Raitakari, JR Attia, D van Heemst, E Kajantie, R Sorice, G Gambaro, RA Scott, AA Hicks, L Ferrucci, M Standl, CM Lindgren, JM Starr, M Karlsson, L Lind, JZ Li, JC Chambers, TA Mori, EJCN de Geus, AC Heath, NG Martin, J Auvinen, BM Buckley, AJM de Craen, M Waldenberger, K Strauch, T Meitinger, RJ Scott, M McEvoy, M Beekman, C Bombieri, PM Ridker, KL Mohlke, NL Pedersen, AC Morrison, DI Boomsma, JB Whitfield, DP Strachan, A Hofman, P Vollenweider, F Cucca, MR Jarvelin, JW Jukema, TD Spector, A Hamsten, T Zeller, AG Uitterlinden, M Nauck, V Gudnason, L Qi, H Grallert, IB Borecki, JI Rotter, W März, PS Wild, ML Lokki, M Boyle, V Salomaa, M Melbye, JG Eriksson, JF Wilson, BWJH Penninx, DM Becker, BB Worrall, G Gibson, RM Krauss, M Ciullo, G Zaza, NJ Wareham, AJ Oldehinkel, LJ Palmer, SS Murray, PP Pramstaller, S Bandinelli, J Heinrich, E Ingelsson, IJ Deary, R Mägi, L Vandenput, P van der Harst, KC Desch, JS Kooner, C Ohlsson, C Hayward, T Lehtimäki, AR Shuldiner, DK Arnett, LJ Beilin, A Robino, P Froguel, M Pirastu, T Jess, W Koenig, RJF Loos, DA Evans, H Schmidt, GD Smith, PE Slagboom, G Eiriksdottir, AP Morris, BM Psaty, RP Tracy, IM Nolte, E Boerwinkle, S Visvikis-Siest, AP Reiner, M Gross, JC Bis, L Franke, OH Franco, EJ Benjamin, DI Chasman, J Dupuis, H Snieder, A Dehghan, BZ Alizadeh
Publication Date: 2018-11-01

Variant appearance in text: rs4660293
PubMed Link: 30388399
PubMed Central Link
Variant Present in the following documents:
  • mmc2.xlsx
View BVdb publication page



Genetic Variants Associated With Plasma Lipids Are Associated With the Lipid Response to Niacin.

Journal Of The American Heart Association
S Tuteja, L Qu, M Vujkovic, RL Dunbar, J Chen, S DerOhannessian, DJ Rader
Publication Date: 2018-10-02

Variant appearance in text: rs4660293
PubMed Link: 30371334
PubMed Central Link
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.

Nature Communications
A Xue, Y Wu, Z Zhu, F Zhang, KE Kemper, Z Zheng, L Yengo, LR Lloyd-Jones, J Sidorenko, Y Wu, , AF McRae, PM Visscher, J Zeng, J Yang
Publication Date: 2018-07-27

Variant appearance in text: rs4660293
PubMed Link: 30054458
PubMed Central Link
Variant Present in the following documents:
  • 41467_2018_4951_MOESM15_ESM.xlsx
View BVdb publication page



Risk of Neuropsychiatric Adverse Effects of Lipid-Lowering Drugs: A Mendelian Randomization Study.

The International Journal Of Neuropsychopharmacology
J Alghamdi, S Matou-Nasri, F Alghamdi, S Alghamdi, M Alfadhel, S Padmanabhan
Publication Date: 2018-12-01

Variant appearance in text: rs4660293
PubMed Link: 29986042
PubMed Central Link
Variant Present in the following documents:
  • pyy060_suppl_supplementary_tables.xlsx
View BVdb publication page



Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries.

Nature Communications
SM Zekavat, S Ruotsalainen, RE Handsaker, M Alver, J Bloom, T Poterba, C Seed, J Ernst, M Chaffin, J Engreitz, GM Peloso, A Manichaikul, C Yang, KA Ryan, M Fu, WC Johnson, M Tsai, M Budoff, RS Vasan, LA Cupples, JI Rotter, SS Rich, W Post, BD Mitchell, A Correa, A Metspalu, JG Wilson, V Salomaa, M Kellis, MJ Daly, BM Neale, S McCarroll, I Surakka, T Esko, A Ganna, S Ripatti, S Kathiresan, P Natarajan,
Publication Date: 2018-07-04

Variant appearance in text: rs4660293
PubMed Link: 29973585
PubMed Central Link
Variant Present in the following documents:
  • 41467_2018_4668_MOESM9_ESM.xlsx
  • 41467_2018_4668_MOESM18_ESM.xlsx
  • 41467_2018_4668_MOESM13_ESM.xlsx
  • 41467_2018_4668_MOESM10_ESM.xlsx
  • 41467_2018_4668_MOESM15_ESM.xlsx
  • 41467_2018_4668_MOESM14_ESM.xlsx
  • 41467_2018_4668_MOESM11_ESM.xlsx
  • 41467_2018_4668_MOESM12_ESM.xlsx
  • 41467_2018_4668_MOESM16_ESM.xlsx
View BVdb publication page



Brief Overview of a Decade of Genome-Wide Association Studies on Primary Hypertension.

International Journal Of Endocrinology
AB Azam, EAB Azizan
Publication Date: 2018

Variant appearance in text: rs4660293
PubMed Link: 29666641
PubMed Central Link
Variant Present in the following documents:
  • Main text
View BVdb publication page



Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes.

Aging
AM Kulminski, J Huang, Y Loika, KG Arbeev, O Bagley, A Yashkin, M Duan, I Culminskaya
Publication Date: 2018-03-29

Variant appearance in text: rs4660293
PubMed Link: 29615537
PubMed Central Link
Variant Present in the following documents:
  • aging-10-101407-s003.xlsx
View BVdb publication page



Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

Nature Genetics
R Malik, G Chauhan, M Traylor, M Sargurupremraj, Y Okada, A Mishra, L Rutten-Jacobs, AK Giese, SW van der Laan, S Gretarsdottir, CD Anderson, M Chong, HHH Adams, T Ago, P Almgren, P Amouyel, H Ay, TM Bartz, OR Benavente, S Bevan, GB Boncoraglio, RD Brown, AS Butterworth, C Carrera, CL Carty, DI Chasman, WM Chen, JW Cole, A Correa, I Cotlarciuc, C Cruchaga, J Danesh, PIW de Bakker, AL DeStefano, M den Hoed, Q Duan, ST Engelter, GJ Falcone, RF Gottesman, RP Grewal, V Gudnason, S Gustafsson, J Haessler, TB Harris, A Hassan, AS Havulinna, SR Heckbert, EG Holliday, G Howard, FC Hsu, HI Hyacinth, MA Ikram, E Ingelsson, MR Irvin, X Jian, J Jiménez-Conde, JA Johnson, JW Jukema, M Kanai, KL Keene, BM Kissela, DO Kleindorfer, C Kooperberg, M Kubo, LA Lange, CD Langefeld, C Langenberg, LJ Launer, JM Lee, R Lemmens, D Leys, CM Lewis, WY Lin, AG Lindgren, E Lorentzen, PK Magnusson, J Maguire, A Manichaikul, PF McArdle, JF Meschia, BD Mitchell, TH Mosley, MA Nalls, T Ninomiya, MJ O'Donnell, BM Psaty, SL Pulit, K Rannikmäe, AP Reiner, KM Rexrode, K Rice, SS Rich, PM Ridker, NS Rost, PM Rothwell, JI Rotter, T Rundek, RL Sacco, S Sakaue, MM Sale, V Salomaa, BR Sapkota, R Schmidt, CO Schmidt, U Schminke, P Sharma, A Slowik, CLM Sudlow, C Tanislav, T Tatlisumak, KD Taylor, VNS Thijs, G Thorleifsson, U Thorsteinsdottir, S Tiedt, S Trompet, C Tzourio, CM van Duijn, M Walters, NJ Wareham, S Wassertheil-Smoller, JG Wilson, KL Wiggins, Q Yang, S Yusuf, , , , , , JC Bis, T Pastinen, A Ruusalepp, EE Schadt, S Koplev, JLM Björkegren, V Codoni, M Civelek, NL Smith, DA Trégouët, IE Christophersen, C Roselli, SA Lubitz, PT Ellinor, ES Tai, JS Kooner, N Kato, J He, P van der Harst, P Elliott, JC Chambers, F Takeuchi, AD Johnson, , , , , , , , , , , DK Sanghera, O Melander, C Jern, D Strbian, I Fernandez-Cadenas, WT Longstreth, A Rolfs, J Hata, D Woo, J Rosand, G Pare, JC Hopewell, D Saleheen, K Stefansson, BB Worrall, SJ Kittner, S Seshadri, M Fornage, HS Markus, JMM Howson, Y Kamatani, S Debette, M Dichgans
Publication Date: 2018-04

Variant appearance in text: rs4660293
PubMed Link: 29531354
PubMed Central Link
Variant Present in the following documents:
  • NIHMS959658-supplement-Supplementary_Table_27.xlsx
View BVdb publication page



Influence of obesity-related risk factors in the aetiology of glioma.

British Journal Of Cancer
L Disney-Hogg, A Sud, PJ Law, AJ Cornish, B Kinnersley, QT Ostrom, K Labreche, JE Eckel-Passow, GN Armstrong, EB Claus, D Il'yasova, J Schildkraut, JS Barnholtz-Sloan, SH Olson, JL Bernstein, RK Lai, AJ Swerdlow, M Simon, P Hoffmann, MM Nöthen, KH Jöckel, S Chanock, P Rajaraman, C Johansen, RB Jenkins, BS Melin, MR Wrensch, M Sanson, ML Bondy, RS Houlston
Publication Date: 2018-04

Variant appearance in text: rs4660293
PubMed Link: 29531326
PubMed Central Link
Variant Present in the following documents:
  • 41416_2018_9_MOESM1_ESM.docx
  • 41416_2018_9_MOESM2_ESM.xlsx
View BVdb publication page



Integrative analysis of omics summary data reveals putative mechanisms underlying complex traits.

Nature Communications
Y Wu, J Zeng, F Zhang, Z Zhu, T Qi, Z Zheng, LR Lloyd-Jones, RE Marioni, NG Martin, GW Montgomery, IJ Deary, NR Wray, PM Visscher, AF McRae, J Yang
Publication Date: 2018-03-02

Variant appearance in text: rs4660293
PubMed Link: 29500431
PubMed Central Link
Variant Present in the following documents:
  • 41467_2018_3371_MOESM7_ESM.xlsx
View BVdb publication page



Visit-to-visit lipid variability: Clinical significance, effects of lipid-lowering treatment, and (pharmaco) genetics.

Journal Of Clinical Lipidology
RAJ Smit, JW Jukema, I Postmus, I Ford, PE Slagboom, BT Heijmans, S Le Cessie, S Trompet
Publication Date: 2018

Variant appearance in text: rs4660293
PubMed Link: 29422286
PubMed Central Link
Variant Present in the following documents:
  • Supplemental file
View BVdb publication page



Interactions between Genetics and Sugar-Sweetened Beverage Consumption on Health Outcomes: A Review of Gene-Diet Interaction Studies.

Frontiers In Endocrinology
DE Haslam, NM McKeown, MA Herman, AH Lichtenstein, HS Dashti
Publication Date: 2017

Variant appearance in text: rs4660293
PubMed Link: 29375475
PubMed Central Link
Variant Present in the following documents:
  • Main text
View BVdb publication page



Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.

Nature Communications
S Bonàs-Guarch, M Guindo-Martínez, I Miguel-Escalada, N Grarup, D Sebastian, E Rodriguez-Fos, F Sánchez, M Planas-Fèlix, P Cortes-Sánchez, S González, P Timshel, TH Pers, CC Morgan, I Moran, G Atla, JR González, M Puiggros, J Martí, EA Andersson, C Díaz, RM Badia, M Udler, A Leong, V Kaur, J Flannick, T Jørgensen, A Linneberg, ME Jørgensen, DR Witte, C Christensen, I Brandslund, EV Appel, RA Scott, J Luan, C Langenberg, NJ Wareham, O Pedersen, A Zorzano, JC Florez, T Hansen, J Ferrer, JM Mercader, D Torrents
Publication Date: 2018-01-22

Variant appearance in text: rs4660293
PubMed Link: 29358691
PubMed Central Link
Variant Present in the following documents:
  • 41467_2017_2380_MOESM11_ESM.xlsx
View BVdb publication page



Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.

Plos Genetics
JP Davis, JR Huyghe, AE Locke, AU Jackson, X Sim, HM Stringham, TM Teslovich, RP Welch, C Fuchsberger, N Narisu, PS Chines, AJ Kangas, P Soininen, M Ala-Korpela, J Kuusisto, FS Collins, M Laakso, M Boehnke, KL Mohlke
Publication Date: 2017-10

Variant appearance in text: rs4660293
PubMed Link: 29084231
PubMed Central Link
Variant Present in the following documents:
  • pgen.1007079.s011.xlsx
  • pgen.1007079.s010.xlsx
View BVdb publication page



Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease.

Nature Genetics
X Lu, GM Peloso, DJ Liu, Y Wu, H Zhang, W Zhou, J Li, CS Tang, R Dorajoo, H Li, J Long, X Guo, M Xu, CN Spracklen, Y Chen, X Liu, Y Zhang, CC Khor, J Liu, L Sun, L Wang, YT Gao, Y Hu, K Yu, Y Wang, CYY Cheung, F Wang, J Huang, Q Fan, Q Cai, S Chen, J Shi, X Yang, W Zhao, WH Sheu, SS Cherny, M He, AB Feranil, LS Adair, P Gordon-Larsen, S Du, R Varma, YI Chen, XO Shu, KSL Lam, TY Wong, SK Ganesh, Z Mo, K Hveem, LG Fritsche, JB Nielsen, HF Tse, Y Huo, CY Cheng, YE Chen, W Zheng, ES Tai, W Gao, X Lin, W Huang, G Abecasis, , S Kathiresan, KL Mohlke, T Wu, PC Sham, D Gu, CJ Willer
Publication Date: 2017-12

Variant appearance in text: rs4660293
PubMed Link: 29083407
PubMed Central Link
Variant Present in the following documents:
  • NIHMS909133-supplement-2.xlsx
View BVdb publication page



Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.

Plos One
LC Pilling, JL Atkins, MO Duff, RN Beaumont, SE Jones, J Tyrrell, CL Kuo, KS Ruth, MA Tuke, H Yaghootkar, AR Wood, A Murray, MN Weedon, LW Harries, GA Kuchel, L Ferrucci, TM Frayling, D Melzer
Publication Date: 2017

Variant appearance in text: rs4660293
PubMed Link: 28957414
PubMed Central Link
Variant Present in the following documents:
  • pone.0185083.s004.xlsx
View BVdb publication page



Genetically Determined Plasma Lipid Levels and Risk of Diabetic Retinopathy: A Mendelian Randomization Study.

Diabetes
L Sobrin, YH Chong, Q Fan, A Gan, LK Stanwyck, G Kaidonis, JE Craig, J Kim, WL Liao, YC Huang, WJ Lee, YJ Hung, X Guo, Y Hai, E Ipp, S Pollack, H Hancock, A Price, A Penman, P Mitchell, G Liew, AV Smith, V Gudnason, G Tan, BEK Klein, J Kuo, X Li, MW Christiansen, BM Psaty, K Sandow, , RA Jensen, R Klein, MF Cotch, JJ Wang, Y Jia, CJ Chen, YI Chen, JI Rotter, FJ Tsai, CL Hanis, KP Burdon, TY Wong, CY Cheng
Publication Date: 2017-12

Variant appearance in text: rs4660293
PubMed Link: 28951389
PubMed Central Link
Variant Present in the following documents:
  • DB170398SupplementaryData.pdf
View BVdb publication page



Genome-Wide Association Study of Blood Pressure Traits by Hispanic/Latino Background: the Hispanic Community Health Study/Study of Latinos.

Scientific Reports
T Sofer, Q Wong, FP Hartwig, K Taylor, HR Warren, E Evangelou, CP Cabrera, D Levy, H Kramer, LA Lange, BL Horta, , KF Kerr, AP Reiner, N Franceschini
Publication Date: 2017-09-04

Variant appearance in text: rs4660293
PubMed Link: 28871152
PubMed Central Link
Variant Present in the following documents:
  • 41598_2017_9019_MOESM1_ESM.pdf
View BVdb publication page



Evaluating the Causal Relation of ApoA-IV with Disease-Related Traits - A Bidirectional Two-sample Mendelian Randomization Study.

Scientific Reports
S Mack, S Coassin, J Vaucher, F Kronenberg, C Lamina,
Publication Date: 2017-08-18

Variant appearance in text: rs4660293
PubMed Link: 28821713
PubMed Central Link
Variant Present in the following documents:
  • 41598_2017_7213_MOESM1_ESM.pdf
View BVdb publication page



Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.

Hypertension (Dallas, Tex. : 1979)
LV Wain, A Vaez, R Jansen, R Joehanes, PJ van der Most, AM Erzurumluoglu, PF O'Reilly, CP Cabrera, HR Warren, LM Rose, GC Verwoert, JJ Hottenga, RJ Strawbridge, T Esko, DE Arking, SJ Hwang, X Guo, Z Kutalik, S Trompet, N Shrine, A Teumer, JS Ried, JC Bis, AV Smith, N Amin, IM Nolte, LP Lyytikäinen, A Mahajan, NJ Wareham, E Hofer, PK Joshi, K Kristiansson, M Traglia, AS Havulinna, A Goel, MA Nalls, S Sõber, D Vuckovic, J Luan, F Del Greco M, KL Ayers, J Marrugat, D Ruggiero, LM Lopez, T Niiranen, S Enroth, AU Jackson, CP Nelson, JE Huffman, W Zhang, J Marten, I Gandin, SE Harris, T Zemunik, Y Lu, E Evangelou, N Shah, MH de Borst, M Mangino, BP Prins, A Campbell, R Li-Gao, G Chauhan, C Oldmeadow, G Abecasis, M Abedi, CM Barbieri, MR Barnes, C Batini, J Beilby, T Blake, M Boehnke, EP Bottinger, PS Braund, M Brown, M Brumat, H Campbell, JC Chambers, M Cocca, F Collins, J Connell, HJ Cordell, JJ Damman, G Davies, EJ de Geus, R de Mutsert, J Deelen, Y Demirkale, ASF Doney, M Dörr, M Farrall, T Ferreira, M Frånberg, H Gao, V Giedraitis, C Gieger, F Giulianini, AJ Gow, A Hamsten, TB Harris, A Hofman, EG Holliday, J Hui, MR Jarvelin, Å Johansson, AD Johnson, P Jousilahti, A Jula, M Kähönen, S Kathiresan, KT Khaw, I Kolcic, S Koskinen, C Langenberg, M Larson, LJ Launer, B Lehne, DCM Liewald, L Lin, L Lind, F Mach, C Mamasoula, C Menni, B Mifsud, Y Milaneschi, A Morgan, AD Morris, AC Morrison, PJ Munson, P Nandakumar, QT Nguyen, T Nutile, AJ Oldehinkel, BA Oostra, E Org, S Padmanabhan, A Palotie, G Paré, A Pattie, BWJH Penninx, N Poulter, PP Pramstaller, OT Raitakari, M Ren, K Rice, PM Ridker, H Riese, S Ripatti, A Robino, JI Rotter, I Rudan, Y Saba, A Saint Pierre, CF Sala, AP Sarin, R Schmidt, R Scott, MA Seelen, DC Shields, D Siscovick, R Sorice, A Stanton, DJ Stott, J Sundström, M Swertz, KD Taylor, S Thom, I Tzoulaki, C Tzourio, AG Uitterlinden, U Völker, P Vollenweider, S Wild, G Willemsen, AF Wright, J Yao, S Thériault, D Conen, J Attia, P Sever, S Debette, DO Mook-Kanamori, E Zeggini, TD Spector, P van der Harst, CNA Palmer, AC Vergnaud, RJF Loos, O Polasek, JM Starr, G Girotto, C Hayward, JS Kooner, CM Lindgren, V Vitart, NJ Samani, J Tuomilehto, U Gyllensten, P Knekt, IJ Deary, M Ciullo, R Elosua, BD Keavney, AA Hicks, RA Scott, P Gasparini, M Laan, Y Liu, H Watkins, CA Hartman, V Salomaa, D Toniolo, M Perola, JF Wilson, H Schmidt, JH Zhao, T Lehtimäki, CM van Duijn, V Gudnason, BM Psaty, A Peters, R Rettig, A James, JW Jukema, DP Strachan, W Palmas, A Metspalu, E Ingelsson, DI Boomsma, OH Franco, M Bochud, C Newton-Cheh, PB Munroe, P Elliott, DI Chasman, A Chakravarti, J Knight, AP Morris, D Levy, MD Tobin, H Snieder, MJ Caulfield, GB Ehret
Publication Date: 2017-07-24

Variant appearance in text: rs4660293
PubMed Link: 28739976
PubMed Central Link
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic determinants of inherited susceptibility to hypercholesterolemia - a comprehensive literature review.

Lipids In Health And Disease
CS Paththinige, ND Sirisena, V Dissanayake
Publication Date: 2017-06-02

Variant appearance in text: rs4660293
PubMed Link: 28577571
PubMed Central Link
Variant Present in the following documents:
  • 12944_2017_488_MOESM2_ESM.xlsx
View BVdb publication page



Identification of six polymorphisms as novel susceptibility loci for ischemic or hemorrhagic stroke by exome-wide association studies.

International Journal Of Molecular Medicine
Y Yamada, J Sakuma, I Takeuchi, Y Yasukochi, K Kato, M Oguri, T Fujimaki, H Horibe, M Muramatsu, M Sawabe, Y Fujiwara, Y Taniguchi, S Obuchi, H Kawai, S Shinkai, S Mori, T Arai, M Tanaka
Publication Date: 2017-06

Variant appearance in text: rs4660293
PubMed Link: 28487959
PubMed Central Link
Variant Present in the following documents:
  • Main text
View BVdb publication page



Common and rare genetic markers of lipid variation in subjects with type 2 diabetes from the ACCORD clinical trial.

Peerj
SW Marvel, DM Rotroff, MJ Wagner, JB Buse, TM Havener, HL McLeod, AA Motsinger-Reif,
Publication Date: 2017

Variant appearance in text: rs4660293
PubMed Link: 28480134
PubMed Central Link
Variant Present in the following documents:
  • peerj-05-3187-s002.xlsx
View BVdb publication page



Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study.

Journal Of Cellular And Molecular Medicine
Y Zhu, D Zhang, D Zhou, Z Li, Z Li, L Fang, M Yang, Z Shan, H Li, J Chen, X Zhou, W Ye, S Yu, H Li, L Cai, C Liu, J Zhang, L Wang, Y Lai, L Ruan, Z Sun, S Zhang, H Wang, Y Liu, Y Xu, J Ling, C Xu, Y Zhang, D Lv, Z Yuan, J Zhang, Y Zhang, Y Shi, M Lai
Publication Date: 2017-06

Variant appearance in text: rs4660293
PubMed Link: 28371326
PubMed Central Link
Variant Present in the following documents:
  • JCMM-21-1106-s002.xlsx
View BVdb publication page



Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer.

International Journal Of Cancer
H Rodriguez-Broadbent, PJ Law, A Sud, K Palin, S Tuupanen, A Gylfe, UA Hänninen, T Cajuso, T Tanskanen, J Kondelin, E Kaasinen, AP Sarin, S Ripatti, JG Eriksson, H Rissanen, P Knekt, E Pukkala, P Jousilahti, V Salomaa, A Palotie, L Renkonen-Sinisalo, A Lepistö, J Böhm, JP Mecklin, NA Al-Tassan, C Palles, L Martin, E Barclay, SM Farrington, MN Timofeeva, BF Meyer, SM Wakil, H Campbell, CG Smith, S Idziaszczyk, TS Maughan, R Kaplan, R Kerr, D Kerr, MN Passarelli, JC Figueiredo, DD Buchanan, AK Win, JL Hopper, MA Jenkins, NM Lindor, PA Newcomb, S Gallinger, D Conti, F Schumacher, G Casey, LA Aaltonen, JP Cheadle, IP Tomlinson, MG Dunlop, RS Houlston
Publication Date: 2017-06-15

Variant appearance in text: rs4660293
PubMed Link: 28340513
PubMed Central Link
Variant Present in the following documents:
  • NIHMS79344-supplement-Supplementary_Data.pdf
  • NIHMS79344-supplement-Supplementary_Material.pdf
View BVdb publication page



Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits.

American Journal Of Human Genetics
M Civelek, Y Wu, C Pan, CK Raulerson, A Ko, A He, C Tilford, NK Saleem, A Stančáková, LJ Scott, C Fuchsberger, HM Stringham, AU Jackson, N Narisu, PS Chines, KS Small, J Kuusisto, BW Parks, P Pajukanta, T Kirchgessner, FS Collins, PS Gargalovic, M Boehnke, M Laakso, KL Mohlke, AJ Lusis
Publication Date: 2017-03-02

Variant appearance in text: rs4660293
PubMed Link: 28257690
PubMed Central Link
Variant Present in the following documents:
  • mmc3.xlsx
View BVdb publication page



Genetic contribution to lipid levels in early life based on 158 loci validated in adults: the FAMILY study.

Scientific Reports
S Christie, S Robiou-du-Pont, SS Anand, KM Morrison, SD McDonald, G Paré, SA Atkinson, KK Teo, D Meyre
Publication Date: 2017-03-06

Variant appearance in text: rs4660293
PubMed Link: 28250428
PubMed Central Link
Variant Present in the following documents:
  • 41598_2017_102_MOESM1_ESM.pdf
View BVdb publication page



Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.

Nature Genetics
LV Wain, N Shrine, MS Artigas, AM Erzurumluoglu, B Noyvert, L Bossini-Castillo, M Obeidat, AP Henry, MA Portelli, RJ Hall, CK Billington, TL Rimington, AG Fenech, C John, T Blake, VE Jackson, RJ Allen, BP Prins, , A Campbell, DJ Porteous, MR Jarvelin, M Wielscher, AL James, J Hui, NJ Wareham, JH Zhao, JF Wilson, PK Joshi, B Stubbe, R Rawal, H Schulz, M Imboden, NM Probst-Hensch, S Karrasch, C Gieger, IJ Deary, SE Harris, J Marten, I Rudan, S Enroth, U Gyllensten, SM Kerr, O Polasek, M Kähönen, I Surakka, V Vitart, C Hayward, T Lehtimäki, OT Raitakari, DM Evans, AJ Henderson, CE Pennell, CA Wang, PD Sly, ES Wan, R Busch, BD Hobbs, AA Litonjua, DW Sparrow, A Gulsvik, PS Bakke, JD Crapo, TH Beaty, NN Hansel, RA Mathias, I Ruczinski, KC Barnes, Y Bossé, P Joubert, M van den Berge, CA Brandsma, PD Paré, DD Sin, DC Nickle, K Hao, O Gottesman, FE Dewey, SE Bruse, DJ Carey, HL Kirchner, , S Jonsson, G Thorleifsson, I Jonsdottir, T Gislason, K Stefansson, C Schurmann, G Nadkarni, EP Bottinger, RJ Loos, RG Walters, Z Chen, IY Millwood, J Vaucher, OP Kurmi, L Li, AL Hansell, C Brightling, E Zeggini, MH Cho, EK Silverman, I Sayers, G Trynka, AP Morris, DP Strachan, IP Hall, MD Tobin
Publication Date: 2017-03

Variant appearance in text: rs4660293
PubMed Link: 28166213
PubMed Central Link
Variant Present in the following documents:
  • NIHMS71102-supplement-Supplementary_Tables_3__4__10_and_12.xlsx
View BVdb publication page



Comprehensive Analysis of Established Dyslipidemia-Associated Loci in the Diabetes Prevention Program.

Circulation. Cardiovascular Genetics
TV Varga, AH Winters, KA Jablonski, ES Horton, P Khare-Ranade, WC Knowler, SM Marcovina, F Renström, KE Watson, R Goldberg, JC Florez, TI Pollin, PW Franks
Publication Date: 2016-12

Variant appearance in text: rs4660293
PubMed Link: 27784733
PubMed Central Link
Variant Present in the following documents:
  • NIHMS825913-supplement-001457_-_Supplemental_Material.pdf
View BVdb publication page



Is High-Density Lipoprotein Cholesterol Causally Related to Kidney Function? Evidence From Genetic Epidemiological Studies.

Arteriosclerosis, Thrombosis, And Vascular Biology
S Coassin, S Friedel, A Köttgen, C Lamina, F Kronenberg
Publication Date: 2016-11

Variant appearance in text: rs4660293
PubMed Link: 27687604
PubMed Central Link
Variant Present in the following documents:
  • atv-36-2252-s002.pdf
View BVdb publication page



Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.

Nature Genetics
C Liu, AT Kraja, JA Smith, JA Brody, N Franceschini, JC Bis, K Rice, AC Morrison, Y Lu, S Weiss, X Guo, W Palmas, LW Martin, YD Chen, P Surendran, F Drenos, JP Cook, PL Auer, AY Chu, A Giri, W Zhao, J Jakobsdottir, LA Lin, JM Stafford, N Amin, H Mei, J Yao, A Voorman, , , , , MG Larson, ML Grove, AV Smith, SJ Hwang, H Chen, T Huan, G Kosova, NO Stitziel, S Kathiresan, N Samani, H Schunkert, P Deloukas, , M Li, C Fuchsberger, C Pattaro, M Gorski, , C Kooperberg, GJ Papanicolaou, JE Rossouw, JD Faul, SL Kardia, C Bouchard, LJ Raffel, AG Uitterlinden, OH Franco, RS Vasan, CJ O'Donnell, KD Taylor, K Liu, EP Bottinger, O Gottesman, EW Daw, F Giulianini, S Ganesh, E Salfati, TB Harris, LJ Launer, M Dörr, SB Felix, R Rettig, H Völzke, E Kim, WJ Lee, IT Lee, WH Sheu, KS Tsosie, DR Edwards, Y Liu, A Correa, DR Weir, U Völker, PM Ridker, E Boerwinkle, V Gudnason, AP Reiner, CM van Duijn, IB Borecki, TL Edwards, A Chakravarti, JI Rotter, BM Psaty, RJ Loos, M Fornage, GB Ehret, C Newton-Cheh, D Levy, DI Chasman
Publication Date: 2016-10

Variant appearance in text: rs4660293
PubMed Link: 27618448
PubMed Central Link
Variant Present in the following documents:
  • NIHMS845220-supplement-Supplementary_Figures__Tables__and_Notes.docx
  • Main text
View BVdb publication page



Genetic susceptibility to dyslipidemia and incidence of cardiovascular disease depending on a diet quality index in the Malmö Diet and Cancer cohort.

Genes & Nutrition
S Hellstrand, U Ericson, CA Schulz, I Drake, B Gullberg, B Hedblad, G Engström, M Orho-Melander, E Sonestedt
Publication Date: 2016

Variant appearance in text: rs4660293
PubMed Link: 27551321
PubMed Central Link
Variant Present in the following documents:
  • 12263_2016_536_MOESM1_ESM.docx
View BVdb publication page



Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases.

Science (New York, N.Y.)
O Franzén, R Ermel, A Cohain, NK Akers, A Di Narzo, HA Talukdar, H Foroughi-Asl, C Giambartolomei, JF Fullard, K Sukhavasi, S Köks, LM Gan, C Giannarelli, JC Kovacic, C Betsholtz, B Losic, T Michoel, K Hao, P Roussos, J Skogsberg, A Ruusalepp, EE Schadt, JL Björkegren
Publication Date: 2016-08-19

Variant appearance in text: rs4660293
PubMed Link: 27540175
PubMed Central Link
Variant Present in the following documents:
  • NIHMS865440-supplement-Figure_S41.pdf
View BVdb publication page



Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study.

Plos Medicine
BP Prins, A Abbasi, A Wong, A Vaez, I Nolte, N Franceschini, PE Stuart, J Guterriez Achury, V Mistry, JP Bradfield, AM Valdes, J Bras, A Shatunov, , , , , , , , , , , , , , , C Lu, B Han, S Raychaudhuri, S Bevan, MD Mayes, LC Tsoi, E Evangelou, RP Nair, SF Grant, C Polychronakos, TR Radstake, DA van Heel, ML Dunstan, NW Wood, A Al-Chalabi, A Dehghan, H Hakonarson, HS Markus, JT Elder, J Knight, DE Arking, TD Spector, BP Koeleman, CM van Duijn, J Martin, AP Morris, RK Weersma, C Wijmenga, PB Munroe, JR Perry, JG Pouget, Y Jamshidi, H Snieder, BZ Alizadeh
Publication Date: 2016-06

Variant appearance in text: rs4660293
PubMed Link: 27327646
PubMed Central Link
Variant Present in the following documents:
  • pmed.1001976.s002.xlsx
  • pmed.1001976.s012.xlsx
View BVdb publication page



A Genome-Wide mQTL Analysis in Human Adipose Tissue Identifies Genetic Variants Associated with DNA Methylation, Gene Expression and Metabolic Traits.

Plos One
P Volkov, AH Olsson, L Gillberg, SW Jørgensen, C Brøns, KF Eriksson, L Groop, PA Jansson, E Nilsson, T Rönn, A Vaag, C Ling
Publication Date: 2016

Variant appearance in text: rs4660293
PubMed Link: 27322064
PubMed Central Link
Variant Present in the following documents:
  • pone.0157776.s004.xlsx
View BVdb publication page



Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.

Bmc Genomics
S Ligthart, A Vaez, YH Hsu, , , , R Stolk, AG Uitterlinden, A Hofman, BZ Alizadeh, OH Franco, A Dehghan
Publication Date: 2016-06-10

Variant appearance in text: rs4660293
PubMed Link: 27286809
PubMed Central Link
Variant Present in the following documents:
  • Main text
View BVdb publication page



Targeted exonic sequencing of GWAS loci in the high extremes of the plasma lipids distribution.

Atherosclerosis
AP Patel, GM Peloso, JP Pirruccello, CT Johansen, JB Dubé, DB Larach, MR Ban, GM Dallinge-Thie, N Gupta, M Boehnke, GR Abecasis, JJ Kastelein, GK Hovingh, RA Hegele, DJ Rader, S Kathiresan
Publication Date: 2016-07

Variant appearance in text: rs4660293
PubMed Link: 27182959
PubMed Central Link
Variant Present in the following documents:
  • NIHMS787201-supplement.pdf
View BVdb publication page



Diet Quality and Change in Blood Lipids during 16 Years of Follow-up and Their Interaction with Genetic Risk for Dyslipidemia.

Nutrients
E Sonestedt, S Hellstrand, I Drake, CA Schulz, U Ericson, J Hlebowicz, MM Persson, B Gullberg, B Hedblad, G Engström, M Orho-Melander
Publication Date: 2016-05-09

Variant appearance in text: rs4660293
PubMed Link: 27171109
PubMed Central Link
Variant Present in the following documents:
  • nutrients-08-00274-s001.doc
View BVdb publication page



Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants.

Aging
LC Pilling, JL Atkins, K Bowman, SE Jones, J Tyrrell, RN Beaumont, KS Ruth, MA Tuke, H Yaghootkar, AR Wood, RM Freathy, A Murray, MN Weedon, L Xue, K Lunetta, JM Murabito, LW Harries, JM Robine, C Brayne, GA Kuchel, L Ferrucci, TM Frayling, D Melzer
Publication Date: 2016-03

Variant appearance in text: rs4660293
PubMed Link: 27015805
PubMed Central Link
Variant Present in the following documents:
  • aging-08-547-s003.docx
View BVdb publication page



Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.

Scientific Reports
JE Below, EJ Parra, ER Gamazon, J Torres, S Krithika, S Candille, Y Lu, A Manichakul, J Peralta-Romero, Q Duan, Y Li, AP Morris, O Gottesman, E Bottinger, XQ Wang, KD Taylor, YD Ida Chen, JI Rotter, SS Rich, RJ Loos, H Tang, NJ Cox, M Cruz, CL Hanis, A Valladares-Salgado
Publication Date: 2016-01-19

Variant appearance in text: rs4660293
PubMed Link: 26780889
PubMed Central Link
Variant Present in the following documents:
  • srep19429-s2.xls
View BVdb publication page



Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese.

Nature Communications
CS Tang, H Zhang, CY Cheung, M Xu, JC Ho, W Zhou, SS Cherny, Y Zhang, O Holmen, KW Au, H Yu, L Xu, J Jia, RM Porsch, L Sun, W Xu, H Zheng, LY Wong, Y Mu, J Dou, CH Fong, S Wang, X Hong, L Dong, Y Liao, J Wang, LS Lam, X Su, H Yan, ML Yang, J Chen, CW Siu, G Xie, YC Woo, Y Wu, KC Tan, K Hveem, BM Cheung, S Zöllner, A Xu, Y Eugene Chen, CQ Jiang, Y Zhang, TH Lam, SK Ganesh, Y Huo, PC Sham, KS Lam, CJ Willer, HF Tse, W Gao
Publication Date: 2015-12-22

Variant appearance in text: rs4660293
PubMed Link: 26690388
PubMed Central Link
Variant Present in the following documents:
  • ncomms10206-s1.pdf
View BVdb publication page



Assessment of established HDL-C loci for association with HDL-C levels and type 2 diabetes in Pima Indians.

Diabetologia
AK Nair, P Piaggi, NA McLean, M Kaur, S Kobes, WC Knowler, C Bogardus, RL Hanson, LJ Baier
Publication Date: 2016-03

Variant appearance in text: rs4660293
PubMed Link: 26670163
PubMed Central Link
Variant Present in the following documents:
  • NIHMS745539-supplement-125_2015_3835_MOESM1_ESM.pdf
View BVdb publication page



Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome.

Nature Communications
FR Day, DA Hinds, JY Tung, L Stolk, U Styrkarsdottir, R Saxena, A Bjonnes, L Broer, DB Dunger, BV Halldorsson, DA Lawlor, G Laval, I Mathieson, WL McCardle, Y Louwers, C Meun, S Ring, RA Scott, P Sulem, AG Uitterlinden, NJ Wareham, U Thorsteinsdottir, C Welt, K Stefansson, JSE Laven, KK Ong, JRB Perry
Publication Date: 2015-09-29

Variant appearance in text: rs4660293
PubMed Link: 26416764
PubMed Central Link
Variant Present in the following documents:
  • ncomms9464-s2.xlsx
View BVdb publication page



The Gut Microbiome Contributes to a Substantial Proportion of the Variation in Blood Lipids.

Circulation Research
J Fu, MJ Bonder, MC Cenit, EF Tigchelaar, A Maatman, JA Dekens, E Brandsma, J Marczynska, F Imhann, RK Weersma, L Franke, TW Poon, RJ Xavier, D Gevers, MH Hofker, C Wijmenga, A Zhernakova
Publication Date: 2015-10-09

Variant appearance in text: rs4660293
PubMed Link: 26358192
PubMed Central Link
Variant Present in the following documents:
  • res-117-817-s002.pdf
View BVdb publication page



Differential Genetic Effects on Statin-Induced Changes Across Low-Density Lipoprotein-Related Measures.

Circulation. Cardiovascular Genetics
AY Chu, F Giulianini, BJ Barratt, B Ding, F Nyberg, S Mora, PM Ridker, DI Chasman
Publication Date: 2015-10

Variant appearance in text: rs4660293
PubMed Link: 26273092
PubMed Central Link
Variant Present in the following documents:
  • NIHMS717334-supplement-000962_-_Supplemental_Material.pdf
  • Main text
  • NIHMS717334-supplement-000962_-_PAP.pdf
View BVdb publication page



Evaluation of transethnic fine mapping with population-specific and cosmopolitan imputation reference panels in diverse Asian populations.

European Journal Of Human Genetics : Ejhg
X Wang, CY Cheng, J Liao, X Sim, J Liu, KS Chia, ES Tai, P Little, CC Khor, T Aung, TY Wong, YY Teo
Publication Date: 2016-04

Variant appearance in text: rs4660293
PubMed Link: 26130488
PubMed Central Link
Variant Present in the following documents:
  • ejhg2015150x4.xls
View BVdb publication page



Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study.

Plos Medicine
SD Østergaard, S Mukherjee, SJ Sharp, P Proitsi, LA Lotta, F Day, JR Perry, KL Boehme, S Walter, JS Kauwe, LE Gibbons, , , , EB Larson, JF Powell, C Langenberg, PK Crane, NJ Wareham, RA Scott
Publication Date: 2015-06

Variant appearance in text: rs4660293
PubMed Link: 26079503
PubMed Central Link
Variant Present in the following documents:
  • pmed.1001841.s014.xlsx
View BVdb publication page



Genetic polymorphism of APOB is associated with diabetes mellitus in sickle cell disease.

Human Genetics
X Zhang, W Zhang, SL Saraf, M Nouraie, J Han, M Gowhari, J Hassan, G Miasnikova, A Sergueeva, S Nekhai, R Kittles, RF Machado, JG Garcia, MT Gladwin, MH Steinberg, P Sebastiani, DA McClain, VR Gordeuk
Publication Date: 2015-08

Variant appearance in text: rs4660293
PubMed Link: 26025476
PubMed Central Link
Variant Present in the following documents:
  • NIHMS729106-supplement-Supplemental_Tables.xls
View BVdb publication page



Dissecting the genetics of the human transcriptome identifies novel trait-related trans-eQTLs and corroborates the regulatory relevance of non-protein coding loci†.

Human Molecular Genetics
H Kirsten, H Al-Hasani, L Holdt, A Gross, F Beutner, K Krohn, K Horn, P Ahnert, R Burkhardt, K Reiche, J Hackermüller, M Löffler, D Teupser, J Thiery, M Scholz
Publication Date: 2015-08-15

Variant appearance in text: rs4660293
PubMed Link: 26019233
PubMed Central Link
Variant Present in the following documents:
  • Main text
View BVdb publication page



Gender-specific association between the cytoplasmic poly(A) binding protein 4 rs4660293 single nucleotide polymorphism and serum lipid levels.

Molecular Medicine Reports
J Wu, RX Yin, T Guo, QZ Lin, SW Shen, JQ Sun, GY Shi, JZ Wu, DZ Yang, WX Lin
Publication Date: 2015-09

Variant appearance in text: rs4660293
PubMed Link: 26005159
PubMed Central Link
Variant Present in the following documents:
  • Main text
View BVdb publication page



The impact of low-frequency and rare variants on lipid levels.

Nature Genetics
I Surakka, M Horikoshi, R Mägi, AP Sarin, A Mahajan, V Lagou, L Marullo, T Ferreira, B Miraglio, S Timonen, J Kettunen, M Pirinen, J Karjalainen, G Thorleifsson, S Hägg, JJ Hottenga, A Isaacs, C Ladenvall, M Beekman, T Esko, JS Ried, CP Nelson, C Willenborg, S Gustafsson, HJ Westra, M Blades, AJ de Craen, EJ de Geus, J Deelen, H Grallert, A Hamsten, AS Havulinna, C Hengstenberg, JJ Houwing-Duistermaat, E Hyppönen, LC Karssen, T Lehtimäki, V Lyssenko, PK Magnusson, E Mihailov, M Müller-Nurasyid, JP Mpindi, NL Pedersen, BW Penninx, M Perola, TH Pers, A Peters, J Rung, JH Smit, V Steinthorsdottir, MD Tobin, N Tsernikova, EM van Leeuwen, JS Viikari, SM Willems, G Willemsen, H Schunkert, J Erdmann, NJ Samani, J Kaprio, L Lind, C Gieger, A Metspalu, PE Slagboom, L Groop, CM van Duijn, JG Eriksson, A Jula, V Salomaa, DI Boomsma, C Power, OT Raitakari, E Ingelsson, MR Järvelin, U Thorsteinsdottir, L Franke, E Ikonen, O Kallioniemi, V Pietiäinen, CM Lindgren, K Stefansson, A Palotie, MI McCarthy, AP Morris, I Prokopenko, S Ripatti,
Publication Date: 2015-06

Variant appearance in text: rs4660293
PubMed Link: 25961943
PubMed Central Link
Variant Present in the following documents:
  • NIHMS67068-supplement-Supplementary_tables_1-7__9-14.docx
View BVdb publication page



The association between carbohydrate-rich foods and risk of cardiovascular disease is not modified by genetic susceptibility to dyslipidemia as determined by 80 validated variants.

Plos One
E Sonestedt, S Hellstrand, CA Schulz, P Wallström, I Drake, U Ericson, B Gullberg, B Hedblad, M Orho-Melander
Publication Date: 2015

Variant appearance in text: rs4660293
PubMed Link: 25898210
PubMed Central Link
Variant Present in the following documents:
  • pone.0126104.s004.doc
View BVdb publication page



Pleiotropy among common genetic loci identified for cardiometabolic disorders and C-reactive protein.

Plos One
S Ligthart, PS de Vries, AG Uitterlinden, A Hofman, , OH Franco, DI Chasman, A Dehghan
Publication Date: 2015

Variant appearance in text: rs4660293
PubMed Link: 25768928
PubMed Central Link
Variant Present in the following documents:
  • Main text
  • pone.0118859.s004.docx
  • pone.0118859.s003.docx
View BVdb publication page



Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis.

Nature Communications
B Benyamin, T Esko, JS Ried, A Radhakrishnan, SH Vermeulen, M Traglia, M Gögele, D Anderson, L Broer, C Podmore, J Luan, Z Kutalik, S Sanna, P van der Meer, T Tanaka, F Wang, HJ Westra, L Franke, E Mihailov, L Milani, J Hälldin, J Häldin, J Winkelmann, T Meitinger, J Thiery, A Peters, M Waldenberger, A Rendon, J Jolley, J Sambrook, LA Kiemeney, FC Sweep, CF Sala, C Schwienbacher, I Pichler, J Hui, A Demirkan, A Isaacs, N Amin, M Steri, G Waeber, N Verweij, JE Powell, DR Nyholt, AC Heath, PA Madden, PM Visscher, MJ Wright, GW Montgomery, NG Martin, D Hernandez, S Bandinelli, P van der Harst, M Uda, P Vollenweider, RA Scott, C Langenberg, NJ Wareham, , C van Duijn, J Beilby, PP Pramstaller, AA Hicks, WH Ouwehand, K Oexle, C Gieger, A Metspalu, C Camaschella, D Toniolo, DW Swinkels, JB Whitfield
Publication Date: 2014-10-29

Variant appearance in text: rs4660293
PubMed Link: 25352340
PubMed Central Link
Variant Present in the following documents:
  • NIHMS619770-supplement-1.pdf
View BVdb publication page



Using multivariable Mendelian randomization to disentangle the causal effects of lipid fractions.

Plos One
S Burgess, DF Freitag, H Khan, DN Gorman, SG Thompson
Publication Date: 2014

Variant appearance in text: rs4660293
PubMed Link: 25302496
PubMed Central Link
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic predisposition to increased blood cholesterol and triglyceride lipid levels and risk of Alzheimer disease: a Mendelian randomization analysis.

Plos Medicine
P Proitsi, MK Lupton, L Velayudhan, S Newhouse, I Fogh, M Tsolaki, M Daniilidou, M Pritchard, I Kloszewska, H Soininen, P Mecocci, B Vellas, , J Williams, , R Stewart, P Sham, S Lovestone, JF Powell
Publication Date: 2014-09

Variant appearance in text: rs4660293
PubMed Link: 25226301
PubMed Central Link
Variant Present in the following documents:
  • pmed.1001713.s003.xlsx
View BVdb publication page



Genetic determinants of long-term changes in blood lipid concentrations: 10-year follow-up of the GLACIER study.

Plos Genetics
TV Varga, E Sonestedt, D Shungin, RW Koivula, G Hallmans, SA Escher, I Barroso, P Nilsson, O Melander, M Orho-Melander, F Renström, PW Franks
Publication Date: 2014-06

Variant appearance in text: rs4660293
PubMed Link: 24922540
PubMed Central Link
Variant Present in the following documents:
  • pgen.1004388.s003.xlsx
  • pgen.1004388.s005.pdf
View BVdb publication page



Mapping the genetic architecture of gene regulation in whole blood.

Plos One
K Schramm, C Marzi, C Schurmann, M Carstensen, E Reinmaa, R Biffar, G Eckstein, C Gieger, HJ Grabe, G Homuth, G Kastenmüller, R Mägi, A Metspalu, E Mihailov, A Peters, A Petersmann, M Roden, K Strauch, K Suhre, A Teumer, U Völker, H Völzke, R Wang-Sattler, M Waldenberger, T Meitinger, T Illig, C Herder, H Grallert, H Prokisch
Publication Date: 2014

Variant appearance in text: rs4660293
PubMed Link: 24740359
PubMed Central Link
Variant Present in the following documents:
  • pone.0093844.s005.xls
View BVdb publication page



Interrogating causal pathways linking genetic variants, small molecule metabolites, and circulating lipids.

Genome Medicine
SY Shin, AK Petersen, S Wahl, G Zhai, W Römisch-Margl, KS Small, A Döring, BS Kato, A Peters, E Grundberg, C Prehn, R Wang-Sattler, HE Wichmann, MH de Angelis, T Illig, J Adamski, P Deloukas, TD Spector, K Suhre, C Gieger, N Soranzo
Publication Date: 2014

Variant appearance in text: rs4660293
PubMed Link: 24678845
PubMed Central Link
Variant Present in the following documents:
  • gm542-S1.xlsx
View BVdb publication page



Pathogenesis of coronary artery disease: focus on genetic risk factors and identification of genetic variants.

The Application Of Clinical Genetics
S Sayols-Baixeras, C Lluís-Ganella, G Lucas, R Elosua
Publication Date: 2014

Variant appearance in text: rs4660293
PubMed Link: 24520200
PubMed Central Link
Variant Present in the following documents:
  • Main text
View BVdb publication page



Discovery and refinement of loci associated with lipid levels.

Nature Genetics
CJ Willer, EM Schmidt, S Sengupta, GM Peloso, S Gustafsson, S Kanoni, A Ganna, J Chen, ML Buchkovich, S Mora, JS Beckmann, JL Bragg-Gresham, HY Chang, A Demirkan, HM Den Hertog, R Do, LA Donnelly, GB Ehret, T Esko, MF Feitosa, T Ferreira, K Fischer, P Fontanillas, RM Fraser, DF Freitag, D Gurdasani, K Heikkilä, E Hyppönen, A Isaacs, AU Jackson, Å Johansson, T Johnson, M Kaakinen, J Kettunen, ME Kleber, X Li, J Luan, LP Lyytikäinen, PKE Magnusson, M Mangino, E Mihailov, ME Montasser, M Müller-Nurasyid, IM Nolte, JR O'Connell, CD Palmer, M Perola, AK Petersen, S Sanna, R Saxena, SK Service, S Shah, D Shungin, C Sidore, C Song, RJ Strawbridge, I Surakka, T Tanaka, TM Teslovich, G Thorleifsson, EG Van den Herik, BF Voight, KA Volcik, LL Waite, A Wong, Y Wu, W Zhang, D Absher, G Asiki, I Barroso, LF Been, JL Bolton, LL Bonnycastle, P Brambilla, MS Burnett, G Cesana, M Dimitriou, ASF Doney, A Döring, P Elliott, SE Epstein, G Ingi Eyjolfsson, B Gigante, MO Goodarzi, H Grallert, ML Gravito, CJ Groves, G Hallmans, AL Hartikainen, C Hayward, D Hernandez, AA Hicks, H Holm, YJ Hung, T Illig, MR Jones, P Kaleebu, JJP Kastelein, KT Khaw, E Kim, N Klopp, P Komulainen, M Kumari, C Langenberg, T Lehtimäki, SY Lin, J Lindström, RJF Loos, F Mach, WL McArdle, C Meisinger, BD Mitchell, G Müller, R Nagaraja, N Narisu, TVM Nieminen, RN Nsubuga, I Olafsson, KK Ong, A Palotie, T Papamarkou, C Pomilla, A Pouta, DJ Rader, MP Reilly, PM Ridker, F Rivadeneira, I Rudan, A Ruokonen, N Samani, H Scharnagl, J Seeley, K Silander, A Stančáková, K Stirrups, AJ Swift, L Tiret, AG Uitterlinden, LJ van Pelt, S Vedantam, N Wainwright, C Wijmenga, SH Wild, G Willemsen, T Wilsgaard, JF Wilson, EH Young, JH Zhao, LS Adair, D Arveiler, TL Assimes, S Bandinelli, F Bennett, M Bochud, BO Boehm, DI Boomsma, IB Borecki, SR Bornstein, P Bovet, M Burnier, H Campbell, A Chakravarti, JC Chambers, YI Chen, FS Collins, RS Cooper, J Danesh, G Dedoussis, U de Faire, AB Feranil, J Ferrières, L Ferrucci, NB Freimer, C Gieger, LC Groop, V Gudnason, U Gyllensten, A Hamsten, TB Harris, A Hingorani, JN Hirschhorn, A Hofman, GK Hovingh, CA Hsiung, SE Humphries, SC Hunt, K Hveem, C Iribarren, MR Järvelin, A Jula, M Kähönen, J Kaprio, A Kesäniemi, M Kivimaki, JS Kooner, PJ Koudstaal, RM Krauss, D Kuh, J Kuusisto, KO Kyvik, M Laakso, TA Lakka, L Lind, CM Lindgren, NG Martin, W März, MI McCarthy, CA McKenzie, P Meneton, A Metspalu, L Moilanen, AD Morris, PB Munroe, I Njølstad, NL Pedersen, C Power, PP Pramstaller, JF Price, BM Psaty, T Quertermous, R Rauramaa, D Saleheen, V Salomaa, DK Sanghera, J Saramies, PEH Schwarz, WH Sheu, AR Shuldiner, A Siegbahn, TD Spector, K Stefansson, DP Strachan, BO Tayo, E Tremoli, J Tuomilehto, M Uusitupa, CM van Duijn, P Vollenweider, L Wallentin, NJ Wareham, JB Whitfield, BHR Wolffenbuttel, JM Ordovas, E Boerwinkle, CNA Palmer, U Thorsteinsdottir, DI Chasman, JI Rotter, PW Franks, S Ripatti, LA Cupples, MS Sandhu, SS Rich, M Boehnke, P Deloukas, S Kathiresan, KL Mohlke, E Ingelsson, GR Abecasis,
Publication Date: 2013-11

Variant appearance in text: rs4660293
PubMed Link: 24097068
PubMed Central Link
Variant Present in the following documents:
  • NIHMS524703-supplement-1.pdf
View BVdb publication page



Common variants associated with plasma triglycerides and risk for coronary artery disease.

Nature Genetics
R Do, CJ Willer, EM Schmidt, S Sengupta, C Gao, GM Peloso, S Gustafsson, S Kanoni, A Ganna, J Chen, ML Buchkovich, S Mora, JS Beckmann, JL Bragg-Gresham, HY Chang, A Demirkan, HM Den Hertog, LA Donnelly, GB Ehret, T Esko, MF Feitosa, T Ferreira, K Fischer, P Fontanillas, RM Fraser, DF Freitag, D Gurdasani, K Heikkilä, E Hyppönen, A Isaacs, AU Jackson, A Johansson, T Johnson, M Kaakinen, J Kettunen, ME Kleber, X Li, J Luan, LP Lyytikäinen, PK Magnusson, M Mangino, E Mihailov, ME Montasser, M Müller-Nurasyid, IM Nolte, JR O'Connell, CD Palmer, M Perola, AK Petersen, S Sanna, R Saxena, SK Service, S Shah, D Shungin, C Sidore, C Song, RJ Strawbridge, I Surakka, T Tanaka, TM Teslovich, G Thorleifsson, EG Van den Herik, BF Voight, KA Volcik, LL Waite, A Wong, Y Wu, W Zhang, D Absher, G Asiki, I Barroso, LF Been, JL Bolton, LL Bonnycastle, P Brambilla, MS Burnett, G Cesana, M Dimitriou, AS Doney, A Döring, P Elliott, SE Epstein, GI Eyjolfsson, B Gigante, MO Goodarzi, H Grallert, ML Gravito, CJ Groves, G Hallmans, AL Hartikainen, C Hayward, D Hernandez, AA Hicks, H Holm, YJ Hung, T Illig, MR Jones, P Kaleebu, JJ Kastelein, KT Khaw, E Kim, N Klopp, P Komulainen, M Kumari, C Langenberg, T Lehtimäki, SY Lin, J Lindström, RJ Loos, F Mach, WL McArdle, C Meisinger, BD Mitchell, G Müller, R Nagaraja, N Narisu, TV Nieminen, RN Nsubuga, I Olafsson, KK Ong, A Palotie, T Papamarkou, C Pomilla, A Pouta, DJ Rader, MP Reilly, PM Ridker, F Rivadeneira, I Rudan, A Ruokonen, N Samani, H Scharnagl, J Seeley, K Silander, A Stančáková, K Stirrups, AJ Swift, L Tiret, AG Uitterlinden, LJ van Pelt, S Vedantam, N Wainwright, C Wijmenga, SH Wild, G Willemsen, T Wilsgaard, JF Wilson, EH Young, JH Zhao, LS Adair, D Arveiler, TL Assimes, S Bandinelli, F Bennett, M Bochud, BO Boehm, DI Boomsma, IB Borecki, SR Bornstein, P Bovet, M Burnier, H Campbell, A Chakravarti, JC Chambers, YD Chen, FS Collins, RS Cooper, J Danesh, G Dedoussis, U de Faire, AB Feranil, J Ferrières, L Ferrucci, NB Freimer, C Gieger, LC Groop, V Gudnason, U Gyllensten, A Hamsten, TB Harris, A Hingorani, JN Hirschhorn, A Hofman, GK Hovingh, CA Hsiung, SE Humphries, SC Hunt, K Hveem, C Iribarren, MR Järvelin, A Jula, M Kähönen, J Kaprio, A Kesäniemi, M Kivimaki, JS Kooner, PJ Koudstaal, RM Krauss, D Kuh, J Kuusisto, KO Kyvik, M Laakso, TA Lakka, L Lind, CM Lindgren, NG Martin, W März, MI McCarthy, CA McKenzie, P Meneton, A Metspalu, L Moilanen, AD Morris, PB Munroe, I Njølstad, NL Pedersen, C Power, PP Pramstaller, JF Price, BM Psaty, T Quertermous, R Rauramaa, D Saleheen, V Salomaa, DK Sanghera, J Saramies, PE Schwarz, WH Sheu, AR Shuldiner, A Siegbahn, TD Spector, K Stefansson, DP Strachan, BO Tayo, E Tremoli, J Tuomilehto, M Uusitupa, CM van Duijn, P Vollenweider, L Wallentin, NJ Wareham, JB Whitfield, BH Wolffenbuttel, D Altshuler, JM Ordovas, E Boerwinkle, CN Palmer, U Thorsteinsdottir, DI Chasman, JI Rotter, PW Franks, S Ripatti, LA Cupples, MS Sandhu, SS Rich, M Boehnke, P Deloukas, KL Mohlke, E Ingelsson, GR Abecasis, MJ Daly, BM Neale, S Kathiresan
Publication Date: 2013-11

Variant appearance in text: rs4660293
PubMed Link: 24097064
PubMed Central Link
Variant Present in the following documents:
  • NIHMS524704-supplement-1.pdf
View BVdb publication page



A multiethnic replication study of plasma lipoprotein levels-associated SNPs identified in recent GWAS.

Plos One
EK Bryant, AS Dressen, CH Bunker, JE Hokanson, RF Hamman, MI Kamboh, FY Demirci
Publication Date: 2013

Variant appearance in text: rs4660293
PubMed Link: 23717430
PubMed Central Link
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.

Journal Of Medical Genetics
D Weissglas-Volkov, CA Aguilar-Salinas, E Nikkola, KA Deere, I Cruz-Bautista, O Arellano-Campos, LL Muñoz-Hernandez, L Gomez-Munguia, ML Ordoñez-Sánchez, PM Reddy, AJ Lusis, N Matikainen, MR Taskinen, L Riba, RM Cantor, JS Sinsheimer, T Tusie-Luna, P Pajukanta
Publication Date: 2013-05

Variant appearance in text: rs4660293
PubMed Link: 23505323
PubMed Central Link
Variant Present in the following documents:
  • NIHMS454100-supplement-Supplementary_Table6.xls
View BVdb publication page



Alternative transcript annotations:

Transcript cDNA Protein Consequence Exon Intron
ENST00000372856.3 c.1582-92T>C - intron_variant - 11/14
ENST00000372857.3 c.1621-92T>C - intron_variant - 12/15
ENST00000372858.3 c.1669-92T>C - intron_variant - 12/15
ENST00000372862.3 c.1534-92T>C - intron_variant - 11/14
ENST00000421687.2 c.1374-128T>C - intron_variant - 11/13
ENST00000437136.1 c.285-92T>C - intron_variant - 3/6
ENST00000468476.1 n.2019T>C - non_coding_transcript_exon_variant 1/2 -
ENST00000484555.1 n.418-92T>C - intron_variant,non_coding_transcript_variant - 2/2
ENST00000492468.1 n.1531T>C - non_coding_transcript_exon_variant 1/4 -
NM_001135653.2 c.1669-92T>C - intron_variant - 12/15
NM_001135654.2 c.1582-92T>C - intron_variant - 11/14
NM_003819.4 c.1621-92T>C - intron_variant - 12/15