Publications:

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Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes.

Nature Genetics

Robertson, Catherine C CC; Inshaw, Jamie R J JRJ; Onengut-Gumuscu, Suna S; Chen, Wei-Min WM; Santa Cruz, David Flores DF; Yang, Hanzhi H; Cutler, Antony J AJ; Crouch, Daniel J M DJM; Farber, Emily E; Bridges, S Louis SL; Edberg, Jeffrey C JC; Kimberly, Robert P RP; Buckner, Jane H JH; Deloukas, Panos P; Divers, Jasmin J; Dabelea, Dana D; Lawrence, Jean M JM; Marcovina, Santica S; Shah, Amy S AS; Greenbaum, Carla J CJ; Atkinson, Mark A MA; Gregersen, Peter K PK; Oksenberg, Jorge R JR; Pociot, Flemming F; Rewers, Marian J MJ; Steck, Andrea K AK; Dunger, David B DB; , ; Wicker, Linda S LS; Concannon, Patrick P; Todd, John A JA; Rich, Stephen S SS

Publication Date: 2021-07

Variant appearance in text: rs2269241

PubMed Link: 34127860

Variant Present in the following documents:

• Main text

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Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes.

Nature Genetics

Robertson, Catherine C CC; Inshaw, Jamie R J JRJ; Onengut-Gumuscu, Suna S; Chen, Wei-Min WM; Santa Cruz, David Flores DF; Yang, Hanzhi H; Cutler, Antony J AJ; Crouch, Daniel J M DJM; Farber, Emily E; Bridges, S Louis SL; Edberg, Jeffrey C JC; Kimberly, Robert P RP; Buckner, Jane H JH; Deloukas, Panos P; Divers, Jasmin J; Dabelea, Dana D; Lawrence, Jean M JM; Marcovina, Santica S; Shah, Amy S AS; Greenbaum, Carla J CJ; Atkinson, Mark A MA; Gregersen, Peter K PK; Oksenberg, Jorge R JR; Pociot, Flemming F; Rewers, Marian J MJ; Steck, Andrea K AK; Dunger, David B DB; , ; Wicker, Linda S LS; Concannon, Patrick P; Todd, John A JA; Rich, Stephen S SS

Publication Date: 2021-07

Variant appearance in text: rs2269241

PubMed Link: 34127860

Variant Present in the following documents:

• Main text

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Rare Genetic Variants of Large Effect Influence Risk of Type 1 Diabetes.

Diabetes

Forgetta, Vincenzo V; Manousaki, Despoina D; Istomine, Roman R; Ross, Stephanie S; Tessier, Marie-Catherine MC; Marchand, Luc L; Li, Min M; Qu, Hui-Qi HQ; Bradfield, Jonathan P JP; Grant, Struan F A SFA; Hakonarson, Hakon H; , ; Paterson, Andrew D AD; Piccirillo, Ciriaco C; Polychronakos, Constantin C; Richards, J Brent JB

Publication Date: 2020-04

Variant appearance in text: rs2269241

PubMed Link: 32005708

Variant Present in the following documents:

• Main text
• db190831.pdf

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Systematic Evaluation of Genes and Genetic Variants Associated with Type 1 Diabetes Susceptibility.

Journal Of Immunology (Baltimore, Md. : 1950)

Ram, Ramesh R; Mehta, Munish M; Nguyen, Quang T QT; Larma, Irma I; Boehm, Bernhard O BO; Pociot, Flemming F; Concannon, Patrick P; Morahan, Grant G

Publication Date: 2016-04-01

Variant appearance in text: rs2269241

PubMed Link: 26912320

Variant Present in the following documents:

• Main text

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Genetic Risk Score Modelling for Disease Progression in New-Onset Type 1 Diabetes Patients: Increased Genetic Load of Islet-Expressed and Cytokine-Regulated Candidate Genes Predicts Poorer Glycemic Control.

Journal Of Diabetes Research

Brorsson, Caroline A CA; Nielsen, Lotte B LB; Andersen, Marie Louise ML; Kaur, Simranjeet S; Bergholdt, Regine R; Hansen, Lars L; Mortensen, Henrik B HB; Pociot, Flemming F; Størling, Joachim J; ,

Publication Date: 2016

Variant appearance in text: rs2269241

PubMed Link: 26904692

Variant Present in the following documents:

• Main text
• JDR2016-9570424.pdf

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Genome-wide analysis correlates Ayurveda Prakriti.

Scientific Reports

Govindaraj, Periyasamy P; Nizamuddin, Sheikh S; Sharath, Anugula A; Jyothi, Vuskamalla V; Rotti, Harish H; Raval, Ritu R; Nayak, Jayakrishna J; Bhat, Balakrishna K BK; Prasanna, B V BV; Shintre, Pooja P; Sule, Mayura M; Joshi, Kalpana S KS; Dedge, Amrish P AP; Bharadwaj, Ramachandra R; Gangadharan, G G GG; Nair, Sreekumaran S; Gopinath, Puthiya M PM; Patwardhan, Bhushan B; Kondaiah, Paturu P; Satyamoorthy, Kapaettu K; Valiathan, Marthanda Varma Sankaran MV; Thangaraj, Kumarasamy K

Publication Date: 2015-10-29

Variant appearance in text: rs2269241

PubMed Link: 26511157

Variant Present in the following documents:

• Main text
• srep15786.pdf
• srep15786-s1.pdf

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Role of Type 1 Diabetes-Associated SNPs on Risk of Autoantibody Positivity in the TEDDY Study.

Diabetes

Törn, Carina C; Hadley, David D; Lee, Hye-Seung HS; Hagopian, William W; Lernmark, Åke Å; Simell, Olli O; Rewers, Marian M; Ziegler, Anette A; Schatz, Desmond D; Akolkar, Beena B; Onengut-Gumuscu, Suna S; Chen, Wei-Min WM; Toppari, Jorma J; Mykkänen, Juha J; Ilonen, Jorma J; Rich, Stephen S SS; She, Jin-Xiong JX; Steck, Andrea K AK; Krischer, Jeffrey J; ,

Publication Date: 2015-05

Variant appearance in text: rs2269241

PubMed Link: 25422107

Variant Present in the following documents:

• Main text
• db141497.pdf

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Sex-specific differences in effect size estimates at established complex trait loci.

International Journal Of Epidemiology

Orozco, Gisela G; Ioannidis, John P A JP; Morris, Andrew A; Zeggini, Eleftheria E; ,

Publication Date: 2012-10

Variant appearance in text: rs2269241

PubMed Link: 22825589

Variant Present in the following documents:

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Identification of novel type 1 diabetes candidate genes by integrating genome-wide association data, protein-protein interactions, and human pancreatic islet gene expression.

Diabetes

Bergholdt, Regine R; Brorsson, Caroline C; Palleja, Albert A; Berchtold, Lukas A LA; Fløyel, Tina T; Bang-Berthelsen, Claus Heiner CH; Frederiksen, Klaus Stensgaard KS; Jensen, Lars Juhl LJ; Størling, Joachim J; Pociot, Flemming F

Publication Date: 2012-04

Variant appearance in text: rs2269241

PubMed Link: 22344559

Variant Present in the following documents:

• supp_db11-1263_DB111263SupplementaryData.pdf

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Advances and challenges in biomarker development for type 1 diabetes prediction and prevention using omic technologies.

Expert Opinion On Medical Diagnostics

Carey, Colleen C; Purohit, Sharad S; She, Jin-Xiong JX

Publication Date: 2010-09-01

Variant appearance in text: rs2269241

PubMed Link: 20885991

Variant Present in the following documents:

• Main text

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Synthetic associations in the context of genome-wide association scan signals.

Human Molecular Genetics

Orozco, Gisela G; Barrett, Jeffrey C JC; Zeggini, Eleftheria E

Publication Date: 2010-10-15

Variant appearance in text: rs2269241

PubMed Link: 20805105

Variant Present in the following documents:

• Main text

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Genetics of type 1 diabetes: what's next?

Diabetes

Pociot, Flemming F; Akolkar, Beena B; Concannon, Patrick P; Erlich, Henry A HA; Julier, Cécile C; Morahan, Grant G; Nierras, Concepcion R CR; Todd, John A JA; Rich, Stephen S SS; Nerup, Jørn J

Publication Date: 2010-07

Variant appearance in text: rs2269241

PubMed Link: 20587799

Variant Present in the following documents:

• Main text
• zdb1561.pdf

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Detecting purely epistatic multi-locus interactions by an omnibus permutation test on ensembles of two-locus analyses.

Bmc Bioinformatics

Wongseree, Waranyu W; Assawamakin, Anunchai A; Piroonratana, Theera T; Sinsomros, Saravudh S; Limwongse, Chanin C; Chaiyaratana, Nachol N

Publication Date: 2009-09-17

Variant appearance in text: rs2269241

PubMed Link: 19761607

Variant Present in the following documents:

• Main text
• 1471-2105-10-294.pdf

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Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.

Nature Genetics

Barrett, Jeffrey C JC; Clayton, David G DG; Concannon, Patrick P; Akolkar, Beena B; Cooper, Jason D JD; Erlich, Henry A HA; Julier, Cécile C; Morahan, Grant G; Nerup, Jørn J; Nierras, Concepcion C; Plagnol, Vincent V; Pociot, Flemming F; Schuilenburg, Helen H; Smyth, Deborah J DJ; Stevens, Helen H; Todd, John A JA; Walker, Neil M NM; Rich, Stephen S SS; ,

Publication Date: 2009-06

Variant appearance in text: rs2269241

PubMed Link: 19430480

Variant Present in the following documents:

• Main text

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