Microsecond-timescale MD simulation of EGFR minor mutation predicts the structural flexibility of EGFR kinase core that reflects EGFR inhibitor sensitivity.
Npj Precision Oncology
Yoshizawa, Takahiro T; Uchibori, Ken K; Araki, Mitsugu M; Matsumoto, Shigeyuki S; Ma, Biao B; Kanada, Ryo R; Seto, Yosuke Y; Oh-Hara, Tomoko T; Koike, Sumie S; Ariyasu, Ryo R; Kitazono, Satoru S; Ninomiya, Hironori H; Takeuchi, Kengo K; Yanagitani, Noriko N; Takagi, Satoshi S; Kishi, Kazuma K; Fujita, Naoya N; Okuno, Yasushi Y; Nishio, Makoto M; Katayama, Ryohei R
Pathway analysis using genome-wide association study data for coronary restenosis--a potential role for the PARVB gene.
Plos One
Verschuren, Jeffrey J W JJ; Trompet, Stella S; Sampietro, M Lourdes ML; Heijmans, Bastiaan T BT; Koch, Werner W; Kastrati, Adnan A; Houwing-Duistermaat, Jeanine J JJ; Slagboom, P Eline PE; Quax, Paul H A PH; Jukema, J Wouter JW
JAK1 gene polymorphisms are associated with the outcomes of hepatitis B virus infection, but not with α interferon therapy response in a Han Chinese population.