Publications:

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Pharmacogenetics and Adverse Events in the Use of Fluoropyrimidine in a Cohort of Cancer Patients on Standard of Care Treatment in Zimbabwe.

Journal Of Personalized Medicine

Afolabi, Boluwatife Lawrence BL; Mazhindu, Tinashe T; Zedias, Chikwambi C; Borok, Margaret M; Ndlovu, Ntokozo N; Masimirembwa, Collen C; On Behalf Of Consortium For Genomics And Therapeutics In Africa Cgta,

Publication Date: 2023-03-28

Variant appearance in text: DPYD: 557A>G; Y186C; rs115232898

PubMed Link: 37108974

Variant Present in the following documents:

• Main text
• jpm-13-00588.pdf

View BVdb publication page

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Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: DPYD: 557A>G; Tyr186Cys

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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Prevalence of exposure to pharmacogenetic drugs by the Saudis treated at the health care centers of the Ministry of National Guard.

Saudi Pharmaceutical Journal : Spj : The Official Publication Of The Saudi Pharmaceutical Society

Alshabeeb, Mohammad A MA; Alyabsi, Mesnad M; Paras, Bien B

Publication Date: 2022-08

Variant appearance in text: rs115232898

PubMed Link: 36164570

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Real-World Evaluation of a Population Germline Genetic Screening Initiative for Family Medicine Patients.

Journal Of Personalized Medicine

Hutchcraft, Megan Leigh ML; Zhang, Shulin S; Lin, Nan N; Gottschalk, Ginny Lee GL; Keck, James W JW; Belcher, Elizabeth A EA; Sears, Catherine C; Wang, Chi C; Liu, Kun K; Dietz, Lauren E LE; Pickarski, Justine C JC; Wei, Sainan S; Cardarelli, Roberto R; DiPaola, Robert S RS; Kolesar, Jill M JM

Publication Date: 2022-08-08

Variant appearance in text: DPYD: 557A>G

PubMed Link: 36013246

Variant Present in the following documents:

• Main text

View BVdb publication page

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ClinPharmSeq: A targeted sequencing panel for clinical pharmacogenetics implementation.

Plos One

Lee, Seung-Been SB; Shin, Jong-Yeon JY; Kwon, Nak-Jung NJ; Kim, Changhoon C; Seo, Jeong-Sun JS

Publication Date: 2022

Variant appearance in text: DPYD: 557A>G

PubMed Link: 35901010

Variant Present in the following documents:

• pone.0272129.pdf

View BVdb publication page

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Implementing Pharmacogenetic Testing in Gastrointestinal Cancers (IMPACT-GI): Study Protocol for a Pragmatic Implementation Trial for Establishing DPYD and UGT1A1 Screening to Guide Chemotherapy Dosing.

Frontiers In Oncology

Varughese, Lisa A LA; Bhupathiraju, Madhuri M; Hoffecker, Glenda G; Terek, Shannon S; Harr, Margaret M; Hakonarson, Hakon H; Cambareri, Christine C; Marini, Jessica J; Landgraf, Jeffrey J; Chen, Jinbo J; Kanter, Genevieve G; Lau-Min, Kelsey S KS; Massa, Ryan C RC; Damjanov, Nevena N; Reddy, Nandi J NJ; Oyer, Randall A RA; Teitelbaum, Ursina R UR; Tuteja, Sony S

Publication Date: 2022

Variant appearance in text: DPYD: 557A>G; Y186C; rs115232898

PubMed Link: 35865463

Variant Present in the following documents:

• Main text
• fonc-12-859846.pdf

View BVdb publication page

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Testing for Dihydropyrimidine Dehydrogenase Deficiency to Individualize 5-Fluorouracil Therapy.

Cancers

Diasio, Robert B RB; Offer, Steven M SM

Publication Date: 2022-06-30

Variant appearance in text: DPYD: 557A>G; Y186C; rs115232898

PubMed Link: 35804978

Variant Present in the following documents:

• Main text
• cancers-14-03207.pdf

View BVdb publication page

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Pharmacogenetics of Breast Cancer Treatments: A Sub-Saharan Africa Perspective.

Pharmacogenomics And Personalized Medicine

Nthontho, Keneuoe Cecilia KC; Ndlovu, Andrew Khulekani AK; Sharma, Kirthana K; Kasvosve, Ishmael I; Hertz, Daniel Louis DL; Paganotti, Giacomo Maria GM

Publication Date: 2022

Variant appearance in text: DPYD: Y186C; rs115232898

PubMed Link: 35761855

Variant Present in the following documents:

• Main text
• pgpm-15-613.pdf

View BVdb publication page

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Germline variants in cancer therapy.

Cancer Drug Resistance (Alhambra, Calif.)

Kaehler, Meike M; Cascorbi, Ingolf I

Publication Date: 2019

Variant appearance in text: DPYD: Y186C

PubMed Link: 35582146

Variant Present in the following documents:

• cdr-2-18.pdf

View BVdb publication page

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Racial and ethnic differences in capecitabine toxicity in patients with gastrointestinal tract cancers.

Annals Of Gastroenterology

Brazelton, Alicia A; Yande, Soham S; Pope, Rita R; Johnson, Michael L ML; Musher, Benjamin B; Trivedi, Meghana V MV

Publication Date: 2022

Variant appearance in text: DPYD: Y186C

PubMed Link: 35479584

Variant Present in the following documents:

• AnnGastroenterol-35-182.pdf

View BVdb publication page

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Dihydropyrimidine dehydrogenase (DPD) polymorphisms knocking on the door.

Ecancermedicalscience

Donadio, Mauro Daniel Spina MDS; Carraro, Dirce Maria DM; Torrezan, Giovana Tardin GT; de Mello, Celso Abdon Lopes CAL

Publication Date: 2022

Variant appearance in text: DPYD: 557A>G; rs115232898

PubMed Link: 35242225

Variant Present in the following documents:

• Main text
• can-16-1344.pdf

View BVdb publication page

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Application of a next-generation sequencing (NGS) panel in newborn screening efficiently identifies inborn disorders of neonates.

Orphanet Journal Of Rare Diseases

Huang, Xinwen X; Wu, Dingwen D; Zhu, Lin L; Wang, Wenjun W; Yang, Rulai R; Yang, Jianbin J; He, Qunyan Q; Zhu, Bingquan B; You, Ying Y; Xiao, Rui R; Zhao, Zhengyan Z

Publication Date: 2022-02-21

Variant appearance in text: DPYD: 557A>G

PubMed Link: 35193651

Variant Present in the following documents:

• 13023_2022_2231_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Clinical pharmacogenetic analysis in 5,001 individuals with diagnostic Exome Sequencing data.

Npj Genomic Medicine

Lanillos, Javier J; Carcajona, Marta M; Maietta, Paolo P; Alvarez, Sara S; Rodriguez-Antona, Cristina C

Publication Date: 2022-02-18

Variant appearance in text: rs115232898

PubMed Link: 35181665

Variant Present in the following documents:

• Main text
• 41525_2022_Article_283.pdf
• 41525_2022_283_MOESM4_ESM.xlsx, sheet 1
• 41525_2022_283_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines.

Nature Neuroscience

Baxi, Emily G EG; Thompson, Terri T; Li, Jonathan J; Kaye, Julia A JA; Lim, Ryan G RG; Wu, Jie J; Ramamoorthy, Divya D; Lima, Leandro L; Vaibhav, Vineet V; Matlock, Andrea A; Frank, Aaron A; Coyne, Alyssa N AN; Landin, Barry B; Ornelas, Loren L; Mosmiller, Elizabeth E; Thrower, Sara S; Farr, S Michelle SM; Panther, Lindsey L; Gomez, Emilda E; Galvez, Erick E; Perez, Daniel D; Meepe, Imara I; Lei, Susan S; Mandefro, Berhan B; Trost, Hannah H; Pinedo, Louis L; Banuelos, Maria G MG; Liu, Chunyan C; Moran, Ruby R; Garcia, Veronica V; Workman, Michael M; Ho, Richie R; Wyman, Stacia S; Roggenbuck, Jennifer J; Harms, Matthew B MB; Stocksdale, Jennifer J; Miramontes, Ricardo R; Wang, Keona K; Venkatraman, Vidya V; Holewenski, Ronald R; Sundararaman, Niveda N; Pandey, Rakhi R; Manalo, Danica-Mae DM; Donde, Aneesh A; Huynh, Nhan N; Adam, Miriam M; Wassie, Brook T BT; Vertudes, Edward E; Amirani, Naufa N; Raja, Krishna K; Thomas, Reuben R; Hayes, Lindsey L; Lenail, Alex A; Cerezo, Aianna A; Luppino, Sarah S; Farrar, Alanna A; Pothier, Lindsay L; Prina, Carolyn C; Morgan, Todd T; Jamil, Arish A; Heintzman, Sarah S; Jockel-Balsarotti, Jennifer J; Karanja, Elizabeth E; Markway, Jesse J; McCallum, Molly M; Joslin, Ben B; Alibazoglu, Deniz D; Kolb, Stephen S; Ajroud-Driss, Senda S; Baloh, Robert R; Heitzman, Daragh D; Miller, Tim T; Glass, Jonathan D JD; Patel-Murray, Natasha Leanna NL; Yu, Hong H; Sinani, Ervin E; Vigneswaran, Prasha P; Sherman, Alexander V AV; Ahmad, Omar O; Roy, Promit P; Beavers, Jay C JC; Zeiler, Steven S; Krakauer, John W JW; Agurto, Carla C; Cecchi, Guillermo G; Bellard, Mary M; Raghav, Yogindra Y; Sachs, Karen K; Ehrenberger, Tobias T; Bruce, Elizabeth E; Cudkowicz, Merit E ME; Maragakis, Nicholas N; Norel, Raquel R; Van Eyk, Jennifer E JE; Finkbeiner, Steven S; Berry, James J; Sareen, Dhruv D; Thompson, Leslie M LM; Fraenkel, Ernest E; Svendsen, Clive N CN; Rothstein, Jeffrey D JD

Publication Date: 2022-02

Variant appearance in text: DPYD: Y186C; rs115232898

PubMed Link: 35115730

Variant Present in the following documents:

• 41593_2021_1006_MOESM4_ESM.xlsx, sheet 9

View BVdb publication page

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Identification of pharmacogenetic variants from large scale next generation sequencing data in the Saudi population.

Plos One

Goljan, Ewa E; Abouelhoda, Mohammed M; ElKalioby, Mohamed M MM; Jabaan, Amjad A; Alghithi, Nada N; Meyer, Brian F BF; Monies, Dorota D

Publication Date: 2022

Variant appearance in text: DPYD: Y186C; rs115232898

PubMed Link: 35089958

Variant Present in the following documents:

• Main text
• pone.0263137.pdf
• pone.0263137.s001.xlsx, sheet 1

View BVdb publication page

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Ethnic Diversity of DPD Activity and the DPYD Gene: Review of the Literature.

Pharmacogenomics And Personalized Medicine

White, Cassandra C; Scott, Rodney J RJ; Paul, Christine C; Ziolkowski, Andrew A; Mossman, David D; Ackland, Stephen S

Publication Date: 2021

Variant appearance in text: DPYD: 557A>G; Y186C; rs115232898

PubMed Link: 34916829

Variant Present in the following documents:

• Main text
• pgpm-14-1603.pdf

View BVdb publication page

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The Extent and Impact of Variation in ADME Genes in Sub-Saharan African Populations.

Frontiers In Pharmacology

da Rocha, Jorge E B JEB; Othman, Houcemeddine H; Botha, Gerrit G; Cottino, Laura L; Twesigomwe, David D; Ahmed, Samah S; Drögemöller, Britt I BI; Fadlelmola, Faisal M FM; Machanick, Philip P; Mbiyavanga, Mamana M; Panji, Sumir S; Wright, Galen E B GEB; Adebamowo, Clement C; Matshaba, Mogomotsi M; Ramsay, Michéle M; Simo, Gustave G; Simuunza, Martin C MC; Tiemessen, Caroline T CT; Baldwin, Sandra S; Chiano, Mathias M; Cox, Charles C; Gross, Annette S AS; Thomas, Pamela P; Gamo, Francisco-Javier FJ; Hazelhurst, Scott S

Publication Date: 2021

Variant appearance in text: rs115232898

PubMed Link: 34721006

Variant Present in the following documents:

• Main text
• fphar-12-634016.pdf

View BVdb publication page

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Real-World Evaluation of Universal Germline Screening for Cancer Treatment-Relevant Pharmacogenes.

Cancers

Hutchcraft, Megan L ML; Lin, Nan N; Zhang, Shulin S; Sears, Catherine C; Zacholski, Kyle K; Belcher, Elizabeth A EA; Durbin, Eric B EB; Villano, John L JL; Cavnar, Michael J MJ; Arnold, Susanne M SM; Ueland, Frederick R FR; Kolesar, Jill M JM

Publication Date: 2021-09-08

Variant appearance in text: DPYD: 557A>G

PubMed Link: 34572750

Variant Present in the following documents:

• Main text
• cancers-13-04524.pdf

View BVdb publication page

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PriME-PGx: La Princesa University Hospital Multidisciplinary Initiative for the Implementation of Pharmacogenetics.

Journal Of Clinical Medicine

Zubiaur, Pablo P; Mejía-Abril, Gina G; Navares-Gómez, Marcos M; Villapalos-García, Gonzalo G; Soria-Chacartegui, Paula P; Saiz-Rodríguez, Miriam M; Ochoa, Dolores D; Abad-Santos, Francisco F

Publication Date: 2021-08-24

Variant appearance in text: rs115232898

PubMed Link: 34501219

Variant Present in the following documents:

• Main text
• jcm-10-03772.pdf

View BVdb publication page

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DPYD Genotyping in Patients Who Have Planned Cancer Treatment With Fluoropyrimidines: A Health Technology Assessment.

Ontario Health Technology Assessment Series

,

Publication Date: 2021

Variant appearance in text: DPYD: 557A>G; Y186C

PubMed Link: 34484488

Variant Present in the following documents:

• Main text

View BVdb publication page

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Evaluation of population-level pharmacogenetic actionability in Alabama.

Clinical And Translational Science

Davis, Brittney H BH; Williams, Kelly K; Absher, Devin D; Korf, Bruce B; Limdi, Nita A NA

Publication Date: 2021-11

Variant appearance in text: rs115232898

PubMed Link: 34121327

Variant Present in the following documents:

• Main text
• CTS-14-2327.pdf

View BVdb publication page

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Implementing Pharmacogenomics Testing: Single Center Experience at Arkansas Children's Hospital.

Journal Of Personalized Medicine

Gill, Pritmohinder S PS; Yu, Feliciano B FB; Porter-Gill, Patricia A PA; Boyanton, Bobby L BL; Allen, Judy C JC; Farrar, Jason E JE; Veerapandiyan, Aravindhan A; Prodhan, Parthak P; Bielamowicz, Kevin J KJ; Sellars, Elizabeth E; Burrow, Andrew A; Kennedy, Joshua L JL; Clothier, Jeffery L JL; Becton, David L DL; Rule, Don D; Schaefer, G Bradley GB

Publication Date: 2021-05-11

Variant appearance in text: rs115232898

PubMed Link: 34064668

Variant Present in the following documents:

• Main text
• jpm-11-00394.pdf

View BVdb publication page

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An Evaluation of the Diagnostic Accuracy of a Panel of Variants in DPYD and a Single Variant in ENOSF1 for Predicting Common Capecitabine Related Toxicities.

Cancers

Palles, Claire C; Fotheringham, Susan S; Chegwidden, Laura L; Lucas, Marie M; Kerr, Rachel R; Mozolowski, Guy G; Rosmarin, Dan D; Taylor, Jenny C JC; Tomlinson, Ian I; Kerr, David D

Publication Date: 2021-03-24

Variant appearance in text: DPYD: 557A>G; rs115232898

PubMed Link: 33805100

Variant Present in the following documents:

• Main text

View BVdb publication page

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Potential Impact of DPYD Variation on Fluoropyrimidine Drug Response in sub-Saharan African Populations.

Frontiers In Genetics

da Rocha, Jorge E B JEB; Lombard, Zané Z; Ramsay, Michèle M

Publication Date: 2021

Variant appearance in text: rs115232898

PubMed Link: 33767731

Variant Present in the following documents:

• Main text
• fgene-12-626954.pdf

View BVdb publication page

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Impact of pretreatment dihydropyrimidine dehydrogenase genotype-guided fluoropyrimidine dosing on chemotherapy associated adverse events.

Clinical And Translational Science

Wigle, Theodore J TJ; Povitz, Brandi L BL; Medwid, Samantha S; Teft, Wendy A WA; Legan, Robin M RM; Lenehan, John J; Nevison, Stephanie S; Panuganty, Veera V; Keller, Denise D; Mailloux, Jaymie J; Siebring, Victoria V; Sarma, Sisira S; Choi, Yun-Hee YH; Welch, Stephen S; Winquist, Eric E; Schwarz, Ute I UI; Kim, Richard B RB

Publication Date: 2021-07

Variant appearance in text: DPYD: 557A>G

PubMed Link: 33620159

Variant Present in the following documents:

• Main text
• CTS-14-1338.pdf

View BVdb publication page

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Actionable pharmacogenetic variants in Hong Kong Chinese exome sequencing data and projected prescription impact in the Hong Kong population.

Plos Genetics

Yu, Mullin Ho Chung MHC; Chan, Marcus Chun Yin MCY; Chung, Claudia Ching Yan CCY; Li, Andrew Wang Tat AWT; Yip, Chara Yin Wa CYW; Mak, Christopher Chun Yu CCY; Chau, Jeffrey Fong Ting JFT; Lee, Mianne M; Fung, Jasmine Lee Fong JLF; Tsang, Mandy Ho Yin MHY; Chan, Joshua Chun Ki JCK; Wong, Wilfred Hing Sang WHS; Yang, Jing J; Chui, William Chun Ming WCM; Chung, Patrick Ho Yu PHY; Yang, Wanling W; Lee, So Lun SL; Chan, Godfrey Chi Fung GCF; Tam, Paul Kwong Hang PKH; Lau, Yu Lung YL; Tang, Clara Sze Man CSM; Yeung, Kit San KS; Chung, Brian Hon Yin BHY

Publication Date: 2021-02

Variant appearance in text: DPYD: 557A>G; rs115232898

PubMed Link: 33600428

Variant Present in the following documents:

• pgen.1009323.s003.xlsx, sheet 1

View BVdb publication page

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Haplotype structure defines effects of common DPYD variants c.85T > C (rs1801265) and c.496A > G (rs2297595) on dihydropyrimidine dehydrogenase activity: Implication for 5-fluorouracil toxicity.

British Journal Of Clinical Pharmacology

Hamzic, Seid S; Schärer, Dominic D; Offer, Steven M SM; Meulendijks, Didier D; Nakas, Christos C; Diasio, Robert B RB; Fontana, Stefano S; Wehrli, Marc M; Schürch, Stefan S; Amstutz, Ursula U; Largiadèr, Carlo R CR

Publication Date: 2021-08

Variant appearance in text: DPYD: 557A>G; Y186C; rs115232898

PubMed Link: 33491253

Variant Present in the following documents:

• Main text
• BCP-87-3234.pdf

View BVdb publication page

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Implementation of pharmacogenomic testing in oncology care (PhOCus): study protocol of a pragmatic, randomized clinical trial.

Therapeutic Advances In Medical Oncology

Reizine, Natalie N; Vokes, Everett E EE; Liu, Ping P; Truong, Tien M TM; Nanda, Rita R; Fleming, Gini F GF; Catenacci, Daniel V T DVT; Pearson, Alexander T AT; Parsad, Sandeep S; Danahey, Keith K; van Wijk, Xander M R XMR; Yeo, Kiang-Teck J KJ; Ratain, Mark J MJ; O'Donnell, Peter H PH

Publication Date: 2020

Variant appearance in text: DPYD: 557A>G; Y186C; rs115232898

PubMed Link: 33414846

Variant Present in the following documents:

• Main text

View BVdb publication page

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Case report: severe toxicity in an African-American patient receiving FOLFOX carrying uncommon allelic variants in DPYD.

Pharmacogenomics

Sissung, Tristan M TM; Cordes, Lisa L; Peer, Cody J CJ; Gandhy, Shruti S; Redman, Jason J; Strauss, Julius J; Figg, William D WD

Publication Date: 2021-01

Variant appearance in text: DPYD: 557A>G; Y186C; rs115232898

PubMed Link: 33305610

Variant Present in the following documents:

• Main text

View BVdb publication page

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Pharmacogenetic Variants in the DPYD and TYMS Genes are Clinically Significant Predictors of Fluoropyrimidine Toxicity: Are We Ready for Use in our Clinical Practice.

Archives Of Pharmacology And Therapeutics

Saif, Muhammad Wasif MW; Hachem, Hilal H; Purvey, Sneha S; Hamal, Ruchi R; Zhang, Lulu L; Siddiqui, Nauman Saleem NS; Godara, Amandeep A; Diasio, Robert B RB

Publication Date: 2020

Variant appearance in text: DPYD: Y186C; rs115232898

PubMed Link: 33283204

Variant Present in the following documents:

• Main text

View BVdb publication page

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Variation in 100 relevant pharmacogenes among emiratis with insights from understudied populations.

Scientific Reports

Al-Mahayri, Zeina N ZN; Patrinos, George P GP; Wattanapokayakit, Sukanya S; Iemwimangsa, Nareenart N; Fukunaga, Koya K; Mushiroda, Taisei T; Chantratita, Wasun W; Ali, Bassam R BR

Publication Date: 2020-12-04

Variant appearance in text: rs115232898

PubMed Link: 33277594

Variant Present in the following documents:

• Main text
• 41598_2020_Article_78231.pdf
• 41598_2020_78231_MOESM1_ESM.pdf

View BVdb publication page

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The Road so Far in Colorectal Cancer Pharmacogenomics: Are We Closer to Individualised Treatment?

Journal Of Personalized Medicine

Simões, Ana Rita AR; Fernández-Rozadilla, Ceres C; Maroñas, Olalla O; Carracedo, Ángel Á

Publication Date: 2020-11-19

Variant appearance in text: DPYD: 557A>G; Tyr186Cys; rs115232898

PubMed Link: 33228198

Variant Present in the following documents:

• Main text
• jpm-10-00237.pdf

View BVdb publication page

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Individualized Dosing of Fluoropyrimidine-Based Chemotherapy to Prevent Severe Fluoropyrimidine-Related Toxicity: What Are the Options?

Clinical Pharmacology And Therapeutics

Knikman, Jonathan E JE; Gelderblom, Hans H; Beijnen, Jos H JH; Cats, Annemieke A; Guchelaar, Henk-Jan HJ; Henricks, Linda M LM

Publication Date: 2021-03

Variant appearance in text: DPYD: Y186C

PubMed Link: 33020924

Variant Present in the following documents:

• Main text

View BVdb publication page

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Population-scale predictions of DPD and TPMT phenotypes using a quantitative pharmacogene-specific ensemble classifier.

British Journal Of Cancer

Zhou, Yitian Y; Dagli Hernandez, Carolina C; Lauschke, Volker M VM

Publication Date: 2020-12

Variant appearance in text: DPYD: Y186C; rs115232898

PubMed Link: 32973300

Variant Present in the following documents:

• Main text
• 41416_2020_1084_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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A Genotyping/Phenotyping Approach with Careful Clinical Monitoring to Manage the Fluoropyrimidines-Based Therapy: Clinical Cases and Systematic Review of the Literature.

Journal Of Personalized Medicine

Conti, Valeria V; De Bellis, Emanuela E; Manzo, Valentina V; Sabbatino, Francesco F; Iannello, Francesco F; Dal Piaz, Fabrizio F; Izzo, Viviana V; Charlier, Bruno B; Stefanelli, Berenice B; Torsiello, Martina M; Iannaccone, Teresa T; Coglianese, Albino A; Colucci, Francesca F; Pepe, Stefano S; Filippelli, Amelia A

Publication Date: 2020-09-03

Variant appearance in text: DPYD: 557A>G

PubMed Link: 32899374

Variant Present in the following documents:

• Main text
• jpm-10-00113.pdf

View BVdb publication page

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A review on the importance of genotyping and phenotyping in fluoropyrimidine treatment.

Medicine And Pharmacy Reports

Deac, Andrada-Larisa AL; Burz, Claudia Cristina CC; Bocşe, Horea Florin HF; Bocşan, Ioana Corina IC; Buzoianu, Anca-Dana AD

Publication Date: 2020-07

Variant appearance in text: DPYD: Y186C

PubMed Link: 32832886

Variant Present in the following documents:

• Main text
• cm-93-223.pdf

View BVdb publication page

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In Vitro Assessment of Fluoropyrimidine-Metabolizing Enzymes: Dihydropyrimidine Dehydrogenase, Dihydropyrimidinase, and β-Ureidopropionase.

Journal Of Clinical Medicine

Hishinuma, Eiji E; Gutiérrez Rico, Evelyn E; Hiratsuka, Masahiro M

Publication Date: 2020-07-22

Variant appearance in text: DPYD: Y186C; rs115232898

PubMed Link: 32707991

Variant Present in the following documents:

• Main text

View BVdb publication page

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A comprehensive population-based study comparing the phenotype and genotype in a pretherapeutic screen of dihydropyrimidine dehydrogenase deficiency.

British Journal Of Cancer

Pallet, Nicolas N; Hamdane, Salma S; Garinet, Simon S; Blons, Hélène H; Zaanan, Aziz A; Paillaud, Elena E; Taieb, Julien J; Laprevote, Olivier O; Loriot, Marie-Anne MA; Narjoz, Céline C

Publication Date: 2020-09

Variant appearance in text: DPYD: 557A>G; Y186C

PubMed Link: 32595208

Variant Present in the following documents:

• Main text
• 41416_2020_962_MOESM1_ESM.pdf
• 41416_2020_Article_962.pdf

View BVdb publication page

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ToxNav germline genetic testing and PROMinet digital mobile application toxicity monitoring: Results of a prospective single-center clinical utility study-PRECISE study.

Cancer Medicine

Lee, Lennard Y W LYW; Starkey, Thomas T; Sivakumar, Shivan S; Fotheringham, Susan S; Mozolowski, Guy G; Shearwood, Vanessa V; Palles, Claire C; Camilleri, Philip P; Church, David D; Kerr, Rachel R; Kerr, David D

Publication Date: 2019-10

Variant appearance in text: rs115232898

PubMed Link: 31486228

Variant Present in the following documents:

• Main text
• CAM4-8-6305.pdf

View BVdb publication page

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