Publications:

---

A bipartite graph-based expected networks approach identifies DDR genes not associated with TMB yet predictive of immune checkpoint blockade response.

Cell Reports. Medicine

Weir, William H WH; Mucha, Peter J PJ; Kim, William Y WY

Publication Date: 2022-05-17

Variant appearance in text: DPYD: 62G>A; Arg21Gln

PubMed Link: 35584624

Variant Present in the following documents:

• mmc2.xlsx, sheet 4

View BVdb publication page

---

Pharmacogenetics implementation in the clinics: information and guidelines for germline variants.

Cancer Drug Resistance (Alhambra, Calif.)

Olivera, Gladys G; Sendra, Luis L; Herrero, María José MJ; Berlanga, Pablo P; Gargallo, Pablo P; Yáñez, Yania Y; Urtasun, Andrea A; de Mora, Jaime Font JF; Castel, Victoria V; Cañete, Adela A; Aliño, Salvador F SF

Publication Date: 2019

Variant appearance in text: rs80081766

PubMed Link: 35582138

Variant Present in the following documents:

• cdr-2-53.pdf

View BVdb publication page

---

Clinical pharmacogenetic analysis in 5,001 individuals with diagnostic Exome Sequencing data.

Npj Genomic Medicine

Lanillos, Javier J; Carcajona, Marta M; Maietta, Paolo P; Alvarez, Sara S; Rodriguez-Antona, Cristina C

Publication Date: 2022-02-18

Variant appearance in text: DPYD: 62G>A; R21Q

PubMed Link: 35181665

Variant Present in the following documents:

• 41525_2022_283_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

---

The genetic landscape of pancreatic head ductal adenocarcinoma in China and prognosis stratification.

Bmc Cancer

Yang, Yefan Y; Ding, Ying Y; Gong, Yuxi Y; Zhao, Sha S; Li, Mingna M; Li, Xiao X; Song, Guoxin G; Zhai, Boya B; Liu, Jin J; Shao, Yang Y; Zhu, Liuqing L; Pang, Jiaohui J; Ma, Yutong Y; Ou, Qiuxiang Q; Wu, Xue X; Zhang, Zhihong Z

Publication Date: 2022-02-18

Variant appearance in text: DPYD: 62G>A; R21Q

PubMed Link: 35180847

Variant Present in the following documents:

• 12885_2022_9279_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

---

Peritoneal Metastasis After Treated With Abemaciclib Plus Fulvestrant for Metastatic Invasive Lobular Breast Cancer: A Case Report and Review of the Literature.

Frontiers In Endocrinology

Gao, Hong-Fei HF; Zhang, Jun-Sheng JS; Zhang, Qiang-Zu QZ; Zhu, Teng T; Yang, Ci-Qiu CQ; Zhang, Liu-Lu LL; Yang, Mei M; Ji, Fei F; Li, Jie-Qing JQ; Cheng, Min-Yi MY; Niu, Gang G; Wang, Kun K

Publication Date: 2021

Variant appearance in text: DPYD: 62G>A; R21Q

PubMed Link: 34690920

Variant Present in the following documents:

• DataSheet_1.xlsx, sheet 1

View BVdb publication page

---

Implementing Pharmacogenomics Testing: Single Center Experience at Arkansas Children's Hospital.

Journal Of Personalized Medicine

Gill, Pritmohinder S PS; Yu, Feliciano B FB; Porter-Gill, Patricia A PA; Boyanton, Bobby L BL; Allen, Judy C JC; Farrar, Jason E JE; Veerapandiyan, Aravindhan A; Prodhan, Parthak P; Bielamowicz, Kevin J KJ; Sellars, Elizabeth E; Burrow, Andrew A; Kennedy, Joshua L JL; Clothier, Jeffery L JL; Becton, David L DL; Rule, Don D; Schaefer, G Bradley GB

Publication Date: 2021-05-11

Variant appearance in text: rs80081766

PubMed Link: 34064668

Variant Present in the following documents:

• Main text
• jpm-11-00394.pdf

View BVdb publication page

---

Case report: severe toxicity in an African-American patient receiving FOLFOX carrying uncommon allelic variants in DPYD.

Pharmacogenomics

Sissung, Tristan M TM; Cordes, Lisa L; Peer, Cody J CJ; Gandhy, Shruti S; Redman, Jason J; Strauss, Julius J; Figg, William D WD

Publication Date: 2021-01

Variant appearance in text: DPYD: 62G>A; R21Q; rs80081766

PubMed Link: 33305610

Variant Present in the following documents:

• Main text

View BVdb publication page

---

In Vitro Assessment of Fluoropyrimidine-Metabolizing Enzymes: Dihydropyrimidine Dehydrogenase, Dihydropyrimidinase, and β-Ureidopropionase.

Journal Of Clinical Medicine

Hishinuma, Eiji E; Gutiérrez Rico, Evelyn E; Hiratsuka, Masahiro M

Publication Date: 2020-07-22

Variant appearance in text: DPYD: R21Q; rs80081766

PubMed Link: 32707991

Variant Present in the following documents:

• Main text
• jcm-09-02342.pdf

View BVdb publication page

---

Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction of DPYD and fluoropyrimidines.

European Journal Of Human Genetics : Ejhg

Lunenburg, Carin A T C CATC; van der Wouden, Cathelijne H CH; Nijenhuis, Marga M; Crommentuijn-van Rhenen, Mandy H MH; de Boer-Veger, Nienke J NJ; Buunk, Anne Marie AM; Houwink, Elisa J F EJF; Mulder, Hans H; Rongen, Gerard A GA; van Schaik, Ron H N RHN; van der Weide, Jan J; Wilffert, Bob B; Deneer, Vera H M VHM; Swen, Jesse J JJ; Guchelaar, Henk-Jan HJ

Publication Date: 2020-04

Variant appearance in text: DPYD: Arg21Gln; rs80081766

PubMed Link: 31745289

Variant Present in the following documents:

• 41431_2019_Article_540.pdf

View BVdb publication page

---

Pharmacogenomics Clinical Annotation Tool (PharmCAT).

Clinical Pharmacology And Therapeutics

Sangkuhl, Katrin K; Whirl-Carrillo, Michelle M; Whaley, Ryan M RM; Woon, Mark M; Lavertu, Adam A; Altman, Russ B RB; Carter, Lester L; Verma, Anurag A; Ritchie, Marylyn D MD; Klein, Teri E TE

Publication Date: 2020-01

Variant appearance in text: rs80081766

PubMed Link: 31306493

Variant Present in the following documents:

• CPT-107-203-s004.pdf

View BVdb publication page

---

Characterization of ADME gene variation in 21 populations by exome sequencing.

Pharmacogenetics And Genomics

Hovelson, Daniel H DH; Xue, Zhengyu Z; Zawistowski, Matthew M; Ehm, Margaret G MG; Harris, Elizabeth C EC; Stocker, Sophie L SL; Gross, Annette S AS; Jang, In-Jin IJ; Ieiri, Ichiro I; Lee, Jong-Eun JE; Cardon, Lon R LR; Chissoe, Stephanie L SL; Abecasis, Gonçalo G; Nelson, Matthew R MR

Publication Date: 2017-03

Variant appearance in text: rs80081766

PubMed Link: 27984508

Variant Present in the following documents:

• fpc-27-089-s005.xlsx, sheet 2

View BVdb publication page

---

Discovery of novel mutations in the dihydropyrimidine dehydrogenase gene associated with toxicity of fluoropyrimidines and viewpoint on preemptive pharmacogenetic screening in patients.

The Epma Journal

Del Re, Marzia M; Michelucci, Angela A; Di Leo, Angelo A; Cantore, Maurizio M; Bordonaro, Roberto R; Simi, Paolo P; Danesi, Romano R

Publication Date: 2015

Variant appearance in text: DPYD: 62G>A

PubMed Link: 26330892

Variant Present in the following documents:

• Main text
• 13167_2015_Article_39.pdf

View BVdb publication page

---