ABCC2 c.2621-2133C>T

Variant ID: 10-101587931-C-T

NM_000392.3(ABCC2):c.2621-2133C>T

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Genetic and biochemical study of dual hereditary jaundice: Dubin-Johnson and Gilbert's syndromes. Haplotyping and founder effect of deletion in ABCC2.

European Journal Of Human Genetics : Ejhg
Slachtova, Lenka L; Seda, Ondrej O; Behunova, Jana J; Mistrik, Martin M; Martasek, Pavel P
Publication Date: 2016-05

Variant appearance in text: rs2002042
PubMed Link: 26350512
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.

Nature Communications
Postmus, Iris I; Trompet, Stella S; Deshmukh, Harshal A HA; Barnes, Michael R MR; Li, Xiaohui X; Warren, Helen R HR; Chasman, Daniel I DI; Zhou, Kaixin K; Arsenault, Benoit J BJ; Donnelly, Louise A LA; Wiggins, Kerri L KL; Avery, Christy L CL; Griffin, Paula P; Feng, QiPing Q; Taylor, Kent D KD; Li, Guo G; Evans, Daniel S DS; Smith, Albert V AV; de Keyser, Catherine E CE; Johnson, Andrew D AD; de Craen, Anton J M AJ; Stott, David J DJ; Buckley, Brendan M BM; Ford, Ian I; Westendorp, Rudi G J RG; Slagboom, P Eline PE; Sattar, Naveed N; Munroe, Patricia B PB; Sever, Peter P; Poulter, Neil N; Stanton, Alice A; Shields, Denis C DC; O'Brien, Eoin E; Shaw-Hawkins, Sue S; Chen, Y-D Ida YD; Nickerson, Deborah A DA; Smith, Joshua D JD; Dubé, Marie Pierre MP; Boekholdt, S Matthijs SM; Hovingh, G Kees GK; Kastelein, John J P JJ; McKeigue, Paul M PM; Betteridge, John J; Neil, Andrew A; Durrington, Paul N PN; Doney, Alex A; Carr, Fiona F; Morris, Andrew A; McCarthy, Mark I MI; Groop, Leif L; Ahlqvist, Emma E; , ; Bis, Joshua C JC; Rice, Kenneth K; Smith, Nicholas L NL; Lumley, Thomas T; Whitsel, Eric A EA; Stürmer, Til T; Boerwinkle, Eric E; Ngwa, Julius S JS; O'Donnell, Christopher J CJ; Vasan, Ramachandran S RS; Wei, Wei-Qi WQ; Wilke, Russell A RA; Liu, Ching-Ti CT; Sun, Fangui F; Guo, Xiuqing X; Heckbert, Susan R SR; Post, Wendy W; Sotoodehnia, Nona N; Arnold, Alice M AM; Stafford, Jeanette M JM; Ding, Jingzhong J; Herrington, David M DM; Kritchevsky, Stephen B SB; Eiriksdottir, Gudny G; Launer, Leonore J LJ; Harris, Tamara B TB; Chu, Audrey Y AY; Giulianini, Franco F; MacFadyen, Jean G JG; Barratt, Bryan J BJ; Nyberg, Fredrik F; Stricker, Bruno H BH; Uitterlinden, André G AG; Hofman, Albert A; Rivadeneira, Fernando F; Emilsson, Valur V; Franco, Oscar H OH; Ridker, Paul M PM; Gudnason, Vilmundur V; Liu, Yongmei Y; Denny, Joshua C JC; Ballantyne, Christie M CM; Rotter, Jerome I JI; Adrienne Cupples, L L; Psaty, Bruce M BM; Palmer, Colin N A CN; Tardif, Jean-Claude JC; Colhoun, Helen M HM; Hitman, Graham G; Krauss, Ronald M RM; Wouter Jukema, J J; Caulfield, Mark J MJ
Publication Date: 2014-10-28

Variant appearance in text: rs2002042
PubMed Link: 25350695
Variant Present in the following documents:
  • ncomms6068-s1.pdf
View BVdb publication page



Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study.

European Heart Journal
Hopewell, Jemma C JC; Parish, Sarah S; Offer, Alison A; Link, Emma E; Clarke, Robert R; Lathrop, Mark M; Armitage, Jane J; Collins, Rory R; ,
Publication Date: 2013-04

Variant appearance in text: rs2002042
PubMed Link: 23100282
Variant Present in the following documents:
  • Main text
  • ehs344.pdf
View BVdb publication page



A single-nucleotide polymorphism in CYP2B6 leads to >3-fold increases in efavirenz concentrations in plasma and hair among HIV-infected women.

The Journal Of Infectious Diseases
Gandhi, Monica M; Greenblatt, Ruth M RM; Bacchetti, Peter P; Jin, Chengshi C; Huang, Yong Y; Anastos, Kathryn K; Cohen, Mardge M; Dehovitz, Jack A JA; Sharp, Gerald B GB; Gange, Stephen J SJ; Liu, Chenglong C; Hanson, Susan C SC; Aouizerat, Bradley B; ,
Publication Date: 2012-11

Variant appearance in text: rs2002042
PubMed Link: 22927450
Variant Present in the following documents:
  • Main text
View BVdb publication page



Analysis of pharmacogenetic traits in two distinct South African populations.

Human Genomics
Ikediobi, Ogechi O; Aouizerat, Bradley B; Xiao, Yuanyuan Y; Gandhi, Monica M; Gebhardt, Stefan S; Warnich, Louise L
Publication Date: 2011-05

Variant appearance in text: rs2002042
PubMed Link: 21712189
Variant Present in the following documents:
  • Main text
View BVdb publication page



Significant effect of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients.

Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology
Kiyotani, Kazuma K; Mushiroda, Taisei T; Imamura, Chiyo K CK; Hosono, Naoya N; Tsunoda, Tatsuhiko T; Kubo, Michiaki M; Tanigawara, Yusuke Y; Flockhart, David A DA; Desta, Zeruesenay Z; Skaar, Todd C TC; Aki, Fuminori F; Hirata, Koichi K; Takatsuka, Yuichi Y; Okazaki, Minoru M; Ohsumi, Shozo S; Yamakawa, Takashi T; Sasa, Mitsunori M; Nakamura, Yusuke Y; Zembutsu, Hitoshi H
Publication Date: 2010-03-10

Variant appearance in text: rs2002042
PubMed Link: 20124171
Variant Present in the following documents:
  • Main text
View BVdb publication page