Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.
Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Immunogenomic analysis of human brain metastases reveals diverse immune landscapes across genetically distinct tumors.
Cell Reports. Medicine
Álvarez-Prado, Ángel F ÁF; Maas, Roeltje R RR; Soukup, Klara K; Klemm, Florian F; Kornete, Mara M; Krebs, Fanny S FS; Zoete, Vincent V; Berezowska, Sabina S; Brouland, Jean-Philippe JP; Hottinger, Andreas F AF; Daniel, Roy T RT; Hegi, Monika E ME; Joyce, Johanna A JA
Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.
Scientific Reports
Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
Arsenic 3 methyltransferase (AS3MT) automethylates on cysteine residues in vitro.
Archives Of Toxicology
Mersaoui, Sofiane Y SY; Guilbert, Cynthia C; Chou, Hsiang H; Douillet, Christelle C; Bohle, D Scott DS; Stýblo, Miroslav M; Richard, Stéphane S; Mann, Koren K KK
Synonymous single nucleotide polymorphism in arsenic (+3) methyltransferase of the Western mosquitofish (Gambusia affinis) and its gene expression among field populations.
Ecotoxicology (London, England)
Park, Daesik D; Propper, Catherine R CR; Wang, Guangning G; Salanga, Matthew C MC
Recent population genomic insights into the genetic basis of arsenic tolerance in humans: the difficulties of identifying positively selected loci in strongly bottlenecked populations.
Heredity
Apata, Mario M; Pfeifer, Susanne P SP
Publication Date: 2020-02
Variant appearance in text: AS3MT: Met287Thr; rs11191439
Distinctive mutational spectrum and karyotype disruption in long-term cisplatin-treated urothelial carcinoma cell lines.
Scientific Reports
Skowron, Margaretha A MA; Petzsch, Patrick P; Hardt, Karin K; Wagner, Nicholas N; Beier, Manfred M; Stepanow, Stefanie S; Drechsler, Matthias M; Rieder, Harald H; Köhrer, Karl K; Niegisch, Günter G; Hoffmann, Michèle J MJ; Schulz, Wolfgang A WA
Publication Date: 2019-10-09
Variant appearance in text: AS3MT: M287T; rs11191439
Associations between arsenic (+3 oxidation state) methyltransferase (AS3MT) and N-6 adenine-specific DNA methyltransferase 1 (N6AMT1) polymorphisms, arsenic metabolism, and cancer risk in a chilean population.
Environmental And Molecular Mutagenesis
de la Rosa, Rosemarie R; Steinmaus, Craig C; Akers, Nicholas K NK; Conde, Lucia L; Ferreccio, Catterina C; Kalman, David D; Zhang, Kevin R KR; Skibola, Christine F CF; Smith, Allan H AH; Zhang, Luoping L; Smith, Martyn T MT
Publication Date: 2017-07
Variant appearance in text: AS3MT: Met287Thr; rs11191439
Association Between Variants in Arsenic (+3 Oxidation State) Methyltranserase (AS3MT) and Urinary Metabolites of Inorganic Arsenic: Role of Exposure Level.
Toxicological Sciences : An Official Journal Of The Society Of Toxicology
Xu, Xiaofan X; Drobná, Zuzana Z; Voruganti, V Saroja VS; Barron, Keri K; González-Horta, Carmen C; Sánchez-Ramírez, Blanca B; Ballinas-Casarrubias, Lourdes L; Cerón, Roberto Hernández RH; Morales, Damián Viniegra DV; Terrazas, Francisco A Baeza FA; Ishida, María C MC; Gutiérrez-Torres, Daniela S DS; Saunders, R Jesse RJ; Crandell, Jamie J; Fry, Rebecca C RC; Loomis, Dana D; García-Vargas, Gonzalo G GG; Del Razo, Luz M LM; Stýblo, Miroslav M; Mendez, Michelle A MA
Publication Date: 2016-09
Variant appearance in text: AS3MT: M287T; rs11191439
Association between polymorphisms in arsenic metabolism genes and urinary arsenic methylation profiles in girls and boys chronically exposed to arsenic.
Environmental And Molecular Mutagenesis
Recio-Vega, Rogelio R; González-Cortes, Tania T; Olivas-Calderón, Edgar E; Clark Lantz, R R; Jay Gandolfi, A A; Michel-Ramirez, Gladis G
Publication Date: 2016-08
Variant appearance in text: AS3MT: Met287Thr; rs11191439
Analysis of maternal polymorphisms in arsenic (+3 oxidation state)-methyltransferase AS3MT and fetal sex in relation to arsenic metabolism and infant birth outcomes: Implications for risk analysis.
Reproductive Toxicology (Elmsford, N.Y.)
Drobná, Zuzana Z; Martin, Elizabeth E; Kim, Kyung Su KS; Smeester, Lisa L; Bommarito, Paige P; Rubio-Andrade, Marisela M; García-Vargas, Gonzalo G GG; Stýblo, Miroslav M; Zou, Fei F; Fry, Rebecca C RC
Publication Date: 2016-06
Variant appearance in text: AS3MT: Met287Thr; rs11191439
Biological monitoring and the influence of genetic polymorphism of As3MT and GSTs on distribution of urinary arsenic species in occupational exposure workers.
International Archives Of Occupational And Environmental Health
Janasik, Beata B; Reszka, Edyta E; Stanislawska, Magdalena M; Wieczorek, Edyta E; Fendler, Wojciech W; Wasowicz, Wojciech W
Publication Date: 2015-08
Variant appearance in text: CYT19: Met287Thr; rs11191439
Whole-genome sequencing of the world's oldest people.
Plos One
Gierman, Hinco J HJ; Fortney, Kristen K; Roach, Jared C JC; Coles, Natalie S NS; Li, Hong H; Glusman, Gustavo G; Markov, Glenn J GJ; Smith, Justin D JD; Hood, Leroy L; Coles, L Stephen LS; Kim, Stuart K SK
Publication Date: 2014
Variant appearance in text: AS3MT: M287T; rs11191439
Environmental exposure to arsenic, AS3MT polymorphism and prevalence of diabetes in Mexico.
Journal Of Exposure Science & Environmental Epidemiology
Drobná, Zuzana Z; Del Razo, Luz M LM; García-Vargas, Gonzalo G GG; Sánchez-Peña, Luz C LC; Barrera-Hernández, Angel A; Stýblo, Miroslav M; Loomis, Dana D
Publication Date: 2013-03
Variant appearance in text: AS3MT: M287T; rs11191439
Methylation of arsenic by recombinant human wild-type arsenic (+3 oxidation state) methyltransferase and its methionine 287 threonine (M287T) polymorph: Role of glutathione.
Toxicology And Applied Pharmacology
Ding, Lan L; Saunders, R Jesse RJ; Drobná, Zuzana Z; Walton, Felecia S FS; Xun, Pencheng P; Thomas, David J DJ; Stýblo, Miroslav M
Publication Date: 2012-10-01
Variant appearance in text: AS3MT: 860T>C; M287T; rs11191439
Genome-wide association study identifies chromosome 10q24.32 variants associated with arsenic metabolism and toxicity phenotypes in Bangladesh.
Plos Genetics
Pierce, Brandon L BL; Kibriya, Muhammad G MG; Tong, Lin L; Jasmine, Farzana F; Argos, Maria M; Roy, Shantanu S; Paul-Brutus, Rachelle R; Rahaman, Ronald R; Rakibuz-Zaman, Muhammad M; Parvez, Faruque F; Ahmed, Alauddin A; Quasem, Iftekhar I; Hore, Samar K SK; Alam, Shafiul S; Islam, Tariqul T; Slavkovich, Vesna V; Gamble, Mary V MV; Yunus, Md M; Rahman, Mahfuzar M; Baron, John A JA; Graziano, Joseph H JH; Ahsan, Habibul H
Publication Date: 2012
Variant appearance in text: AS3MT: Met287Thr; rs11191439
GSTO and AS3MT genetic polymorphisms and differences in urinary arsenic concentrations among residents in Bangladesh.
Biomarkers : Biochemical Indicators Of Exposure, Response, And Susceptibility To Chemicals
Rodrigues, Ema G EG; Kile, Molly M; Hoffman, Elaine E; Quamruzzaman, Quazi Q; Rahman, Mahmuder M; Mahiuddin, Golam G; Hsueh, Yumei Y; Christiani, David C DC
Publication Date: 2012-05
Variant appearance in text: AS3MT: Met287Thr; rs11191439
A case-control study of polymorphisms in xenobiotic and arsenic metabolism genes and arsenic-related bladder cancer in New Hampshire.
Toxicology Letters
Lesseur, Corina C; Gilbert-Diamond, Diane D; Andrew, Angeline S AS; Ekstrom, Rebecca M RM; Li, Zhongze Z; Kelsey, Karl T KT; Marsit, Carmen J CJ; Karagas, Margaret R MR
Publication Date: 2012-04-05
Variant appearance in text: AS3MT: Met287thr; rs11191439
Indigenous American ancestry is associated with arsenic methylation efficiency in an admixed population of northwest Mexico.
Journal Of Toxicology And Environmental Health. Part A
Gomez-Rubio, Paulina P; Klimentidis, Yann C YC; Cantu-Soto, Ernesto E; Meza-Montenegro, Maria M MM; Billheimer, Dean D; Lu, Zhenqiang Z; Chen, Zhao Z; Klimecki, Walter T WT
Publication Date: 2012
Variant appearance in text: AS3MT: M287T; rs11191439
Association between body mass index and arsenic methylation efficiency in adult women from southwest U.S. and northwest Mexico.
Toxicology And Applied Pharmacology
Gomez-Rubio, Paulina P; Roberge, Jason J; Arendell, Leslie L; Harris, Robin B RB; O'Rourke, Mary K MK; Chen, Zhao Z; Cantu-Soto, Ernesto E; Meza-Montenegro, Maria M MM; Billheimer, Dean D; Lu, Zhenqiang Z; Klimecki, Walter T WT
Publication Date: 2011-04-15
Variant appearance in text: AS3MT: M287T; rs11191439
Polymorphisms in arsenic(+III oxidation state) methyltransferase (AS3MT) predict gene expression of AS3MT as well as arsenic metabolism.
Environmental Health Perspectives
Engström, Karin K; Vahter, Marie M; Mlakar, Simona Jurkovic SJ; Concha, Gabriela G; Nermell, Barbro B; Raqib, Rubhana R; Cardozo, Alejandro A; Broberg, Karin K
Publication Date: 2011-02
Variant appearance in text: AS3MT: Met287Thr; rs11191439
Association of AS3MT polymorphisms and the risk of premalignant arsenic skin lesions.
Toxicology And Applied Pharmacology
Valenzuela, Olga L OL; Drobná, Zuzana Z; Hernández-Castellanos, Erika E; Sánchez-Peña, Luz C LC; García-Vargas, Gonzalo G GG; Borja-Aburto, Víctor H VH; Stýblo, Miroslav M; Del Razo, Luz M LM
Publication Date: 2009-09-01
Variant appearance in text: AS3MT: Met287Thr; rs11191439
Metabolism of low-dose inorganic arsenic in a central European population: influence of sex and genetic polymorphisms.
Environmental Health Perspectives
Lindberg, Anna-Lena AL; Kumar, Rajiv R; Goessler, Walter W; Thirumaran, Ranjit R; Gurzau, Eugen E; Koppova, Kvetoslava K; Rudnai, Peter P; Leonardi, Giovanni G; Fletcher, Tony T; Vahter, Marie M
Developmentally restricted genetic determinants of human arsenic metabolism: association between urinary methylated arsenic and CYT19 polymorphisms in children.
Environmental Health Perspectives
Meza, Maria Mercedes MM; Yu, Lizhi L; Rodriguez, Yelitza Y YY; Guild, Mischa M; Thompson, David D; Gandolfi, A Jay AJ; Klimecki, Walter T WT