CNNM proteins selectively bind to the TRPM7 channel to stimulate divalent cation entry into cells.
Plos Biology
Bai, Zhiyong Z; Feng, Jianlin J; Franken, Gijs A C GAC; Al'Saadi, Namariq N; Cai, Na N; Yu, Albert S AS; Lou, Liping L; Komiya, Yuko Y; Hoenderop, Joost G J JGJ; de Baaij, Jeroen H F JHF; Yue, Lixia L; Runnels, Loren W LW
CNNM proteins selectively bind to the TRPM7 channel to stimulate divalent cation entry into cells.
Plos Biology
Bai, Zhiyong Z; Feng, Jianlin J; Franken, Gijs A C GAC; Al'Saadi, Namariq N; Cai, Na N; Yu, Albert S AS; Lou, Liping L; Komiya, Yuko Y; Hoenderop, Joost G J JGJ; de Baaij, Jeroen H F JHF; Yue, Lixia L; Runnels, Loren W LW
Shaping the Trans-Scale Properties of Schizophrenia via Cerebral Alterations on Magnetic Resonance Imaging and Single-Nucleotide Polymorphisms of Coding and Non-Coding Regions.
Cyclin M2 (CNNM2) knockout mice show mild hypomagnesaemia and developmental defects.
Scientific Reports
Franken, Gijs A C GAC; Seker, Murat M; Bos, Caro C; Siemons, Laura A H LAH; van der Eerden, Bram C J BCJ; Christ, Annabel A; Hoenderop, Joost G J JGJ; Bindels, René J M RJM; Müller, Dominik D; Breiderhoff, Tilman T; de Baaij, Jeroen H F JHF
Identification of methylation changes associated with positive and negative growth deviance in Gambian infants using a targeted methyl sequencing approach of genomic DNA.
Faseb Bioadvances
Quilter, Claire R CR; Harvey, Kerry M KM; Bauer, Julien J; Skinner, Benjamin M BM; Gomez, Maria M; Shrivastava, Manu M; Doel, Andrew M AM; Drammeh, Saikou S; Dunger, David B DB; Moore, Sophie E SE; Ong, Ken K KK; Prentice, Andrew M AM; Bernstein, Robin M RM; Sargent, Carole A CA; Affara, Nabeel A NA
The phenotypic and genetic spectrum of patients with heterozygous mutations in cyclin M2 (CNNM2).
Human Mutation
Franken, Gijs A C GAC; Müller, Dominik D; Mignot, Cyril C; Keren, Boris B; Lévy, Jonathan J; Tabet, Anne-Claude AC; Germanaud, David D; Tejada, María-Isabel MI; Kroes, Hester Y HY; Nievelstein, Rutger A J RAJ; Brimble, Elise E; Ruzhnikov, Maria M; Claverie-Martin, Felix F; Szczepańska, Maria M; Ćuk, Martin M; Latta, Femke F; Konrad, Martin M; Martínez-Cruz, Luis A LA; Bindels, René J M RJM; Hoenderop, Joost G J JGJ; Schlingmann, Karl-Peter KP; de Baaij, Jeroen H F JHF
Target Genes of Autism Risk Loci in Brain Frontal Cortex.
Frontiers In Genetics
Sun, Yan Y; Yao, Xueming X; March, Michael E ME; Meng, Xinyi X; Li, Junyi J; Wei, Zhi Z; Sleiman, Patrick M A PMA; Hakonarson, Hakon H; Xia, Qianghua Q; Li, Jin J
The effect of a genetic variant at the schizophrenia associated AS3MT/BORCS7 locus on striatal dopamine function: A PET imaging study.
Psychiatry Research. Neuroimaging
D'Ambrosio, Enrico E; Dahoun, Tarik T; Pardiñas, Antonio F AF; Veronese, Mattia M; Bloomfield, Michael A P MAP; Jauhar, Sameer S; Bonoldi, Ilaria I; Rogdaki, Maria M; Froudist-Walsh, Sean S; Walters, James T R JTR; Howes, Oliver D OD
Testing the Validity of Taxonic Schizotypy Using Genetic and Environmental Risk Variables.
Schizophrenia Bulletin
Morton, Sarah E SE; O'Hare, Kirstie J M KJM; Maha, Jaimee L K JLK; Nicolson, Max P MP; Machado, Liana L; Topless, Ruth R; Merriman, Tony R TR; Linscott, Richard J RJ
Genetic Evaluation of Schizophrenia Using the Illumina HumanExome Chip.
Plos One
Moons, Tim T; De Hert, Marc M; Gellens, Edith E; Gielen, Leen L; Sweers, Kim K; Jacqmaert, Sigrun S; van Winkel, Ruud R; Vandekerckhove, Philippe P; Claes, Stephan S
White Matter Lesion Progression: Genome-Wide Search for Genetic Influences.
Stroke
Hofer, Edith E; Cavalieri, Margherita M; Bis, Joshua C JC; DeCarli, Charles C; Fornage, Myriam M; Sigurdsson, Sigurdur S; Srikanth, Velandai V; Trompet, Stella S; Verhaaren, Benjamin F J BF; Wolf, Christiane C; Yang, Qiong Q; Adams, Hieab H H HH; Amouyel, Philippe P; Beiser, Alexa A; Buckley, Brendan M BM; Callisaya, Michele M; Chauhan, Ganesh G; de Craen, Anton J M AJ; Dufouil, Carole C; van Duijn, Cornelia M CM; Ford, Ian I; Freudenberger, Paul P; Gottesman, Rebecca F RF; Gudnason, Vilmundur V; Heiss, Gerardo G; Hofman, Albert A; Lumley, Thomas T; Martinez, Oliver O; Mazoyer, Bernard B; Moran, Chris C; Niessen, Wiro J WJ; Phan, Thanh T; Psaty, Bruce M BM; Satizabal, Claudia L CL; Sattar, Naveed N; Schilling, Sabrina S; Shibata, Dean K DK; Slagboom, P Eline PE; Smith, Albert A; Stott, David J DJ; Taylor, Kent D KD; Thomson, Russell R; Töglhofer, Anna M AM; Tzourio, Christophe C; van Buchem, Mark M; Wang, Jing J; Westendorp, Rudi G J RG; Windham, B Gwen BG; Vernooij, Meike W MW; Zijdenbos, Alex A; Beare, Richard R; Debette, Stéphanie S; Ikram, M Arfan MA; Jukema, J Wouter JW; Launer, Lenore J LJ; Longstreth, W T WT; Mosley, Thomas H TH; Seshadri, Sudha S; Schmidt, Helena H; Schmidt, Reinhold R; ,
Schizophrenia risk variants modulate white matter volume across the psychosis spectrum: evidence from two independent cohorts.
Neuroimage. Clinical
Oertel-Knöchel, Viola V; Lancaster, Thomas M TM; Knöchel, Christian C; Stäblein, Michael M; Storchak, Helena H; Reinke, Britta B; Jurcoane, Alina A; Kniep, Jonathan J; Prvulovic, David D; Mantripragada, Kiran K; Tansey, Katherine E KE; O'Donovan, Michael C MC; Owen, Michael J MJ; Linden, David E J DE
Analysis of schizophrenia-related genes and electrophysiological measures reveals ZNF804A association with amplitude of P300b elicited by novel sounds.
Translational Psychiatry
Del Re, E C EC; Bergen, S E SE; Mesholam-Gately, R I RI; Niznikiewicz, M A MA; Goldstein, J M JM; Woo, T U TU; Shenton, M E ME; Seidman, L J LJ; McCarley, R W RW; Petryshen, T L TL
Neurophysiologic effect of GWAS derived schizophrenia and bipolar risk variants.
American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics
Hall, Mei-Hua MH; Levy, Deborah L DL; Salisbury, Dean F DF; Haddad, Steve S; Gallagher, Patience P; Lohan, Mary M; Cohen, Bruce B; Ongür, Dost D; Smoller, Jordan W JW
A population-based study of genetic variation and psychotic experiences in adolescents.
Schizophrenia Bulletin
Zammit, Stanley S; Hamshere, Marian M; Dwyer, Sarah S; Georgiva, Lyudmila L; Timpson, Nic N; Moskvina, Valentina V; Richards, Alexander A; Evans, David M DM; Lewis, Glyn G; Jones, Peter P; Owen, Michael J MJ; O'Donovan, Michael C MC
Nalls, Mike A MA; Saad, Mohamad M; Noyce, Alastair J AJ; Keller, Margaux F MF; Schrag, Anette A; Bestwick, Jonathan P JP; Traynor, Bryan J BJ; Gibbs, J Raphael JR; Hernandez, Dena G DG; Cookson, Mark R MR; Morris, Huw R HR; Williams, Nigel N; Gasser, Thomas T; Heutink, Peter P; Wood, Nick N; Hardy, John J; Martinez, Maria M; Singleton, Andrew B AB; , ; , ; , ; ,
A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation.
Biological Psychiatry
, ; , ; Bramon, Elvira E; Pirinen, Matti M; Strange, Amy A; Lin, Kuang K; Freeman, Colin C; Bellenguez, Céline C; Su, Zhan Z; Band, Gavin G; Pearson, Richard R; Vukcevic, Damjan D; Langford, Cordelia C; Deloukas, Panos P; Hunt, Sarah S; Gray, Emma E; Dronov, Serge S; Potter, Simon C SC; Tashakkori-Ghanbaria, Avazeh A; Edkins, Sarah S; Bumpstead, Suzannah J SJ; Arranz, Maria J MJ; Bakker, Steven S; Bender, Stephan S; Bruggeman, Richard R; Cahn, Wiepke W; Chandler, David D; Collier, David A DA; Crespo-Facorro, Benedicto B; Dazzan, Paola P; de Haan, Lieuwe L; Di Forti, Marta M; Dragović, Milan M; Giegling, Ina I; Hall, Jeremy J; Iyegbe, Conrad C; Jablensky, Assen A; Kahn, René S RS; Kalaydjieva, Luba L; Kravariti, Eugenia E; Lawrie, Stephen S; Linszen, Don H DH; Mata, Ignacio I; McDonald, Colm C; McIntosh, Andrew A; Myin-Germeys, Inez I; Ophoff, Roel A RA; Pariante, Carmine M CM; Paunio, Tiina T; Picchioni, Marco M; , ; Ripke, Stephan S; Rujescu, Dan D; Sauer, Heinrich H; Shaikh, Madiha M; Sussmann, Jessika J; Suvisaari, Jaana J; Tosato, Sarah S; Toulopoulou, Timothea T; Van Os, Jim J; Walshe, Muriel M; Weisbrod, Matthias M; Whalley, Heather H; Wiersma, Durk D; Blackwell, Jenefer M JM; Brown, Matthew A MA; Casas, Juan P JP; Corvin, Aiden A; Duncanson, Audrey A; Jankowski, Janusz A Z JA; Markus, Hugh S HS; Mathew, Christopher G CG; Palmer, Colin N A CN; Plomin, Robert R; Rautanen, Anna A; Sawcer, Stephen J SJ; Trembath, Richard C RC; Wood, Nicholas W NW; Barroso, Ines I; Peltonen, Leena L; Lewis, Cathryn M CM; Murray, Robin M RM; Donnelly, Peter P; Powell, John J; Spencer, Chris C A CC
Meta-analysis indicates that the European GWAS-identified risk SNP rs1344706 within ZNF804A is not associated with schizophrenia in Han Chinese population.
Plos One
Li, Ming M; Zhang, Hui H; Luo, Xiong-jian XJ; Gao, Lei L; Qi, Xue-bin XB; Gourraud, Pierre-Antoine PA; Su, Bing B
Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors.
American Journal Of Human Genetics
Andreassen, Ole A OA; Djurovic, Srdjan S; Thompson, Wesley K WK; Schork, Andrew J AJ; Kendler, Kenneth S KS; O'Donovan, Michael C MC; Rujescu, Dan D; Werge, Thomas T; van de Bunt, Martijn M; Morris, Andrew P AP; McCarthy, Mark I MI; , ; , ; , ; Roddey, J Cooper JC; McEvoy, Linda K LK; Desikan, Rahul S RS; Dale, Anders M AM
Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC.
Molecular Psychiatry
Hamshere, M L ML; Walters, J T R JT; Smith, R R; Richards, A L AL; Green, E E; Grozeva, D D; Jones, I I; Forty, L L; Jones, L L; Gordon-Smith, K K; Riley, B B; O'Neill, F A FA; O'Neill, T T; Kendler, K S KS; Sklar, P P; Purcell, S S; Kranz, J J; , ; , ; , ; Morris, D D; Gill, M M; Holmans, P P; Craddock, N N; Corvin, A A; Owen, M J MJ; O'Donovan, M C MC