Polygenic risk scores predict diabetes complications and their response to intensive blood pressure and glucose control.
Diabetologia
Tremblay, Johanne J; Haloui, Mounsif M; Attaoua, Redha R; Tahir, Ramzan R; Hishmih, Camil C; Harvey, François F; Marois-Blanchet, François-Christophe FC; Long, Carole C; Simon, Paul P; Santucci, Lara L; Hizel, Candan C; Chalmers, John J; Marre, Michel M; Harrap, Stephen S; Cífková, Renata R; Krajčoviechová, Alena A; Matthews, David R DR; Williams, Bryan B; Poulter, Neil N; Zoungas, Sophia S; Colagiuri, Stephen S; Mancia, Giuseppe G; Grobbee, Diederick E DE; Rodgers, Anthony A; Liu, Liusheng L; Agbessi, Mawussé M; Bruat, Vanessa V; Favé, Marie-Julie MJ; Harwood, Michelle P MP; Awadalla, Philip P; Woodward, Mark M; Hussin, Julie G JG; Hamet, Pavel P
Exploration of CYP21A2 and CYP17A1 polymorphisms and preeclampsia risk among Chinese Han population: a large-scale case-control study based on 5021 subjects.
Identifying Interactions between Dietary Sodium, Potassium, Sodium-Potassium Ratios, and FGF5 rs16998073 Variants and Their Associated Risk for Hypertension in Korean Adults.
Nutrients
Jeong, Hyeyun H; Jin, Hyun-Seok HS; Kim, Sung-Soo SS; Shin, Dayeon D
A genome-wide association and replication study of blood pressure in Ugandan early adolescents.
Molecular Genetics & Genomic Medicine
Lule, Swaib A SA; Mentzer, Alexander J AJ; Namara, Benigna B; Muwenzi, Allan G AG; Nassanga, Beatrice B; Kizito, Dennison D; Akurut, Helen H; Lubyayi, Lawrence L; Tumusiime, Josephine J; Zziwa, Christopher C; Akello, Florence F; Gurdasani, Deept D; Sandhu, Manjinder M; Smeeth, Liam L; Elliott, Alison M AM; Webb, Emily L EL
The association of elevated maternal genetic risk scores for hypertension, type 2 diabetes and obesity and having a child with a congenital heart defect.
Plos One
Kaplinski, Michelle M; Taylor, Deanne D; Mitchell, Laura E LE; Hammond, Dorothy A DA; Goldmuntz, Elizabeth E; Agopian, A J AJ; ,
Associations of the hypertension-related single nucleotide polymorphism rs11191548 with high-density lipoprotein cholesterol and leptin in Chinese children.
Bmc Medical Genetics
Wu, Lijun L; Gao, Liwang L; Zhao, Xiaoyuan X; Zhang, Meixian M; Wu, Jianxin J; Mi, Jie J
Parental and offspring contribution of genetic markers of adult blood pressure in early life: The FAMILY study.
Plos One
Robiou-du-Pont, Sébastien S; Anand, Sonia S SS; Morrison, Katherine M KM; McDonald, Sarah D SD; Atkinson, Stephanie A SA; Teo, Koon K KK; Meyre, David D
Towards Precision Medicine for Hypertension: A Review of Genomic, Epigenomic, and Microbiomic Effects on Blood Pressure in Experimental Rat Models and Humans.
Genome-Wide Association Study of Blood Pressure Traits by Hispanic/Latino Background: the Hispanic Community Health Study/Study of Latinos.
Scientific Reports
Sofer, Tamar T; Wong, Quenna Q; Hartwig, Fernando P FP; Taylor, Kent K; Warren, Helen R HR; Evangelou, Evangelos E; Cabrera, Claudia P CP; Levy, Daniel D; Kramer, Holly H; Lange, Leslie A LA; Horta, Bernardo L BL; , ; Kerr, Kathleen F KF; Reiner, Alex P AP; Franceschini, Nora N
Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.
Hypertension (Dallas, Tex. : 1979)
Wain, Louise V LV; Vaez, Ahmad A; Jansen, Rick R; Joehanes, Roby R; van der Most, Peter J PJ; Erzurumluoglu, A Mesut AM; O'Reilly, Paul F PF; Cabrera, Claudia P CP; Warren, Helen R HR; Rose, Lynda M LM; Verwoert, Germaine C GC; Hottenga, Jouke-Jan JJ; Strawbridge, Rona J RJ; Esko, Tonu T; Arking, Dan E DE; Hwang, Shih-Jen SJ; Guo, Xiuqing X; Kutalik, Zoltan Z; Trompet, Stella S; Shrine, Nick N; Teumer, Alexander A; Ried, Janina S JS; Bis, Joshua C JC; Smith, Albert V AV; Amin, Najaf N; Nolte, Ilja M IM; Lyytikäinen, Leo-Pekka LP; Mahajan, Anubha A; Wareham, Nicholas J NJ; Hofer, Edith E; Joshi, Peter K PK; Kristiansson, Kati K; Traglia, Michela M; Havulinna, Aki S AS; Goel, Anuj A; Nalls, Mike A MA; Sõber, Siim S; Vuckovic, Dragana D; Luan, Jian'an J; Del Greco M, Fabiola F; Ayers, Kristin L KL; Marrugat, Jaume J; Ruggiero, Daniela D; Lopez, Lorna M LM; Niiranen, Teemu T; Enroth, Stefan S; Jackson, Anne U AU; Nelson, Christopher P CP; Huffman, Jennifer E JE; Zhang, Weihua W; Marten, Jonathan J; Gandin, Ilaria I; Harris, Sarah E SE; Zemunik, Tatijana T; Lu, Yingchang Y; Evangelou, Evangelos E; Shah, Nabi N; de Borst, Martin H MH; Mangino, Massimo M; Prins, Bram P BP; Campbell, Archie A; Li-Gao, Ruifang R; Chauhan, Ganesh G; Oldmeadow, Christopher C; Abecasis, Gonçalo G; Abedi, Maryam M; Barbieri, Caterina M CM; Barnes, Michael R MR; Batini, Chiara C; Beilby, John J; Blake, Tineka T; Boehnke, Michael M; Bottinger, Erwin P EP; Braund, Peter S PS; Brown, Morris M; Brumat, Marco M; Campbell, Harry H; Chambers, John C JC; Cocca, Massimiliano M; Collins, Francis F; Connell, John J; Cordell, Heather J HJ; Damman, Jeffrey J JJ; Davies, Gail G; de Geus, Eco J EJ; de Mutsert, Renée R; Deelen, Joris J; Demirkale, Yusuf Y; Doney, Alex S F ASF; Dörr, Marcus M; Farrall, Martin M; Ferreira, Teresa T; Frånberg, Mattias M; Gao, He H; Giedraitis, Vilmantas V; Gieger, Christian C; Giulianini, Franco F; Gow, Alan J AJ; Hamsten, Anders A; Harris, Tamara B TB; Hofman, Albert A; Holliday, Elizabeth G EG; Hui, Jennie J; Jarvelin, Marjo-Riitta MR; Johansson, Åsa Å; Johnson, Andrew D AD; Jousilahti, Pekka P; Jula, Antti A; Kähönen, Mika M; Kathiresan, Sekar S; Khaw, Kay-Tee KT; Kolcic, Ivana I; Koskinen, Seppo S; Langenberg, Claudia C; Larson, Marty M; Launer, Lenore J LJ; Lehne, Benjamin B; Liewald, David C M DCM; Lin, Li L; Lind, Lars L; Mach, François F; Mamasoula, Chrysovalanto C; Menni, Cristina C; Mifsud, Borbala B; Milaneschi, Yuri Y; Morgan, Anna A; Morris, Andrew D AD; Morrison, Alanna C AC; Munson, Peter J PJ; Nandakumar, Priyanka P; Nguyen, Quang Tri QT; Nutile, Teresa T; Oldehinkel, Albertine J AJ; Oostra, Ben A BA; Org, Elin E; Padmanabhan, Sandosh S; Palotie, Aarno A; Paré, Guillaume G; Pattie, Alison A; Penninx, Brenda W J H BWJH; Poulter, Neil N; Pramstaller, Peter P PP; Raitakari, Olli T OT; Ren, Meixia M; Rice, Kenneth K; Ridker, Paul M PM; Riese, Harriëtte H; Ripatti, Samuli S; Robino, Antonietta A; Rotter, Jerome I JI; Rudan, Igor I; Saba, Yasaman Y; Saint Pierre, Aude A; Sala, Cinzia F CF; Sarin, Antti-Pekka AP; Schmidt, Reinhold R; Scott, Rodney R; Seelen, Marc A MA; Shields, Denis C DC; Siscovick, David D; Sorice, Rossella R; Stanton, Alice A; Stott, David J DJ; Sundström, Johan J; Swertz, Morris M; Taylor, Kent D KD; Thom, Simon S; Tzoulaki, Ioanna I; Tzourio, Christophe C; Uitterlinden, André G AG; Völker, Uwe U; Vollenweider, Peter P; Wild, Sarah S; Willemsen, Gonneke G; Wright, Alan F AF; Yao, Jie J; Thériault, Sébastien S; Conen, David D; Attia, John J; Sever, Peter P; Debette, Stéphanie S; Mook-Kanamori, Dennis O DO; Zeggini, Eleftheria E; Spector, Tim D TD; van der Harst, Pim P; Palmer, Colin N A CNA; Vergnaud, Anne-Claire AC; Loos, Ruth J F RJF; Polasek, Ozren O; Starr, John M JM; Girotto, Giorgia G; Hayward, Caroline C; Kooner, Jaspal S JS; Lindgren, Cecila M CM; Vitart, Veronique V; Samani, Nilesh J NJ; Tuomilehto, Jaakko J; Gyllensten, Ulf U; Knekt, Paul P; Deary, Ian J IJ; Ciullo, Marina M; Elosua, Roberto R; Keavney, Bernard D BD; Hicks, Andrew A AA; Scott, Robert A RA; Gasparini, Paolo P; Laan, Maris M; Liu, YongMei Y; Watkins, Hugh H; Hartman, Catharina A CA; Salomaa, Veikko V; Toniolo, Daniela D; Perola, Markus M; Wilson, James F JF; Schmidt, Helena H; Zhao, Jing Hua JH; Lehtimäki, Terho T; van Duijn, Cornelia M CM; Gudnason, Vilmundur V; Psaty, Bruce M BM; Peters, Annette A; Rettig, Rainer R; James, Alan A; Jukema, J Wouter JW; Strachan, David P DP; Palmas, Walter W; Metspalu, Andres A; Ingelsson, Erik E; Boomsma, Dorret I DI; Franco, Oscar H OH; Bochud, Murielle M; Newton-Cheh, Christopher C; Munroe, Patricia B PB; Elliott, Paul P; Chasman, Daniel I DI; Chakravarti, Aravinda A; Knight, Joanne J; Morris, Andrew P AP; Levy, Daniel D; Tobin, Martin D MD; Snieder, Harold H; Caulfield, Mark J MJ; Ehret, Georg B GB
Identification of polymorphisms in 12q24.1, ACAD10, and BRAP as novel genetic determinants of blood pressure in Japanese by exome-wide association studies.
Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits.
Genome Medicine
Grassmann, Felix F; Kiel, Christina C; Zimmermann, Martina E ME; Gorski, Mathias M; Grassmann, Veronika V; Stark, Klaus K; , ; Heid, Iris M IM; Weber, Bernhard H F BH
Association of genetic variation with blood pressure traits among East Africans.
Clinical Genetics
Kayima, J J; Liang, J J; Natanzon, Y Y; Nankabirwa, J J; Ssinabulya, I I; Nakibuuka, J J; Katamba, A A; Mayanja-Kizza, H H; Miron, A A; Li, C C; Zhu, X X
Genome-wide associations for birth weight and correlations with adult disease.
Nature
Horikoshi, Momoko M; Beaumont, Robin N RN; Day, Felix R FR; Warrington, Nicole M NM; Kooijman, Marjolein N MN; Fernandez-Tajes, Juan J; Feenstra, Bjarke B; van Zuydam, Natalie R NR; Gaulton, Kyle J KJ; Grarup, Niels N; Bradfield, Jonathan P JP; Strachan, David P DP; Li-Gao, Ruifang R; Ahluwalia, Tarunveer S TS; Kreiner, Eskil E; Rueedi, Rico R; Lyytikäinen, Leo-Pekka LP; Cousminer, Diana L DL; Wu, Ying Y; Thiering, Elisabeth E; Wang, Carol A CA; Have, Christian T CT; Hottenga, Jouke-Jan JJ; Vilor-Tejedor, Natalia N; Joshi, Peter K PK; Boh, Eileen Tai Hui ETH; Ntalla, Ioanna I; Pitkänen, Niina N; Mahajan, Anubha A; van Leeuwen, Elisabeth M EM; Joro, Raimo R; Lagou, Vasiliki V; Nodzenski, Michael M; Diver, Louise A LA; Zondervan, Krina T KT; Bustamante, Mariona M; Marques-Vidal, Pedro P; Mercader, Josep M JM; Bennett, Amanda J AJ; Rahmioglu, Nilufer N; Nyholt, Dale R DR; Ma, Ronald Ching Wan RCW; Tam, Claudia Ha Ting CHT; Tam, Wing Hung WH; , ; Ganesh, Santhi K SK; van Rooij, Frank Ja FJ; Jones, Samuel E SE; Loh, Po-Ru PR; Ruth, Katherine S KS; Tuke, Marcus A MA; Tyrrell, Jessica J; Wood, Andrew R AR; Yaghootkar, Hanieh H; Scholtens, Denise M DM; Paternoster, Lavinia L; Prokopenko, Inga I; Kovacs, Peter P; Atalay, Mustafa M; Willems, Sara M SM; Panoutsopoulou, Kalliope K; Wang, Xu X; Carstensen, Lisbeth L; Geller, Frank F; Schraut, Katharina E KE; Murcia, Mario M; van Beijsterveldt, Catharina Em CE; Willemsen, Gonneke G; Appel, Emil V R EVR; Fonvig, Cilius E CE; Trier, Caecilie C; Tiesler, Carla Mt CM; Standl, Marie M; Kutalik, Zoltán Z; Bonas-Guarch, Sílvia S; Hougaard, David M DM; Sánchez, Friman F; Torrents, David D; Waage, Johannes J; Hollegaard, Mads V MV; de Haan, Hugoline G HG; Rosendaal, Frits R FR; Medina-Gomez, Carolina C; Ring, Susan M SM; Hemani, Gibran G; McMahon, George G; Robertson, Neil R NR; Groves, Christopher J CJ; Langenberg, Claudia C; Luan, Jian'an J; Scott, Robert A RA; Zhao, Jing Hua JH; Mentch, Frank D FD; MacKenzie, Scott M SM; Reynolds, Rebecca M RM; , ; Lowe, William L WL; Tönjes, Anke A; Stumvoll, Michael M; Lindi, Virpi V; Lakka, Timo A TA; van Duijn, Cornelia M CM; Kiess, Wieland W; Körner, Antje A; Sørensen, Thorkild Ia TI; Niinikoski, Harri H; Pahkala, Katja K; Raitakari, Olli T OT; Zeggini, Eleftheria E; Dedoussis, George V GV; Teo, Yik-Ying YY; Saw, Seang-Mei SM; Melbye, Mads M; Campbell, Harry H; Wilson, James F JF; Vrijheid, Martine M; de Geus, Eco Jcn EJ; Boomsma, Dorret I DI; Kadarmideen, Haja N HN; Holm, Jens-Christian JC; Hansen, Torben T; Sebert, Sylvain S; Hattersley, Andrew T AT; Beilin, Lawrence J LJ; Newnham, John P JP; Pennell, Craig E CE; Heinrich, Joachim J; Adair, Linda S LS; Borja, Judith B JB; Mohlke, Karen L KL; Eriksson, Johan G JG; Widén, Elisabeth E EE; Kähönen, Mika M; Viikari, Jorma S JS; Lehtimäki, Terho T; Vollenweider, Peter P; Bønnelykke, Klaus K; Bisgaard, Hans H; Mook-Kanamori, Dennis O DO; Hofman, Albert A; Rivadeneira, Fernando F; Uitterlinden, André G AG; Pisinger, Charlotta C; Pedersen, Oluf O; Power, Christine C; Hyppönen, Elina E; Wareham, Nicholas J NJ; Hakonarson, Hakon H; Davies, Eleanor E; Walker, Brian R BR; Jaddoe, Vincent Wv VW; Jarvelin, Marjo-Riitta MR; Grant, Struan Fa SF; Vaag, Allan A AA; Lawlor, Debbie A DA; Frayling, Timothy M TM; Davey Smith, George G; Morris, Andrew P AP; Ong, Ken K KK; Felix, Janine F JF; Timpson, Nicholas J NJ; Perry, John Rb JR; Evans, David M DM; McCarthy, Mark I MI; Freathy, Rachel M RM
Utility of blood pressure genetic risk score in admixed Hispanic samples.
Journal Of Human Hypertension
Beecham, A H AH; Wang, L L; Vasudeva, N N; Liu, Z Z; Dong, C C; Goldschmidt-Clermont, P J PJ; Pericak-Vance, M A MA; Rundek, T T; Seo, D D; Blanton, S H SH; Sacco, R L RL; Beecham, G W GW
Common Polymorphisms at the CYP17A1 Locus Associate With Steroid Phenotype: Support for Blood Pressure Genome-Wide Association Study Signals at This Locus.
Hypertension (Dallas, Tex. : 1979)
Diver, Louise A LA; MacKenzie, Scott M SM; Fraser, Robert R; McManus, Frances F; Freel, E Marie EM; Alvarez-Madrazo, Samantha S; McClure, John D JD; Friel, Elaine C EC; Hanley, Neil A NA; Dominiczak, Anna F AF; Caulfield, Mark J MJ; Munroe, Patricia B PB; Connell, John M JM; Davies, Eleanor E
The Impact of PNPLA3 rs738409 Genetic Polymorphism and Weight Gain ≥10 kg after Age 20 on Non-Alcoholic Fatty Liver Disease in Non-Obese Japanese Individuals.
Plos One
Nishioji, Kenichi K; Mochizuki, Naomi N; Kobayashi, Masao M; Kamaguchi, Mai M; Sumida, Yoshio Y; Nishimura, Takeshi T; Yamaguchi, Kanji K; Kadotani, Hiroshi H; Itoh, Yoshito Y
Sequence analysis of six blood pressure candidate regions in 4,178 individuals: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study.
Plos One
Morrison, Alanna C AC; Bis, Joshua C JC; Hwang, Shih-Jen SJ; Ehret, Georg B GB; Lumley, Thomas T; Rice, Kenneth K; Muzny, Donna D; Gibbs, Richard A RA; Boerwinkle, Eric E; Psaty, Bruce M BM; Chakravarti, Aravinda A; Levy, Daniel D