Effects of Pre-Pregnancy Overweight/Obesity on the Pattern of Association of Hypertension Susceptibility Genes with Preeclampsia.
Life (Basel, Switzerland)
Abramova, Maria M; Churnosova, Maria M; Efremova, Olesya O; Aristova, Inna I; Reshetnikov, Evgeny E; Polonikov, Alexey A; Churnosov, Mikhail M; Ponomarenko, Irina I
Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed.
Cell Genomics
Taub, Margaret A MA; Conomos, Matthew P MP; Keener, Rebecca R; Iyer, Kruthika R KR; Weinstock, Joshua S JS; Yanek, Lisa R LR; Lane, John J; Miller-Fleming, Tyne W TW; Brody, Jennifer A JA; Raffield, Laura M LM; McHugh, Caitlin P CP; Jain, Deepti D; Gogarten, Stephanie M SM; Laurie, Cecelia A CA; Keramati, Ali A; Arvanitis, Marios M; Smith, Albert V AV; Heavner, Benjamin B; Barwick, Lucas L; Becker, Lewis C LC; Bis, Joshua C JC; Blangero, John J; Bleecker, Eugene R ER; Burchard, Esteban G EG; Celedón, Juan C JC; Chang, Yen Pei C YPC; Custer, Brian B; Darbar, Dawood D; de Las Fuentes, Lisa L; DeMeo, Dawn L DL; Freedman, Barry I BI; Garrett, Melanie E ME; Gladwin, Mark T MT; Heckbert, Susan R SR; Hidalgo, Bertha A BA; Irvin, Marguerite R MR; Islam, Talat T; Johnson, W Craig WC; Kaab, Stefan S; Launer, Lenore L; Lee, Jiwon J; Liu, Simin S; Moscati, Arden A; North, Kari E KE; Peyser, Patricia A PA; Rafaels, Nicholas N; Seidman, Christine C; Weeks, Daniel E DE; Wen, Fayun F; Wheeler, Marsha M MM; Williams, L Keoki LK; Yang, Ivana V IV; Zhao, Wei W; Aslibekyan, Stella S; Auer, Paul L PL; Bowden, Donald W DW; Cade, Brian E BE; Chen, Zhanghua Z; Cho, Michael H MH; Cupples, L Adrienne LA; Curran, Joanne E JE; Daya, Michelle M; Deka, Ranjan R; Eng, Celeste C; Fingerlin, Tasha E TE; Guo, Xiuqing X; Hou, Lifang L; Hwang, Shih-Jen SJ; Johnsen, Jill M JM; Kenny, Eimear E EE; Levin, Albert M AM; Liu, Chunyu C; Minster, Ryan L RL; Naseri, Take T; Nouraie, Mehdi M; Reupena, Muagututi'a Sefuiva MS; Sabino, Ester C EC; Smith, Jennifer A JA; Smith, Nicholas L NL; Su, Jessica Lasky JL; Taylor, James G JG; Telen, Marilyn J MJ; Tiwari, Hemant K HK; Tracy, Russell P RP; White, Marquitta J MJ; Zhang, Yingze Y; Wiggins, Kerri L KL; Weiss, Scott T ST; Vasan, Ramachandran S RS; Taylor, Kent D KD; Sinner, Moritz F MF; Silverman, Edwin K EK; Shoemaker, M Benjamin MB; Sheu, Wayne H-H WH; Sciurba, Frank F; Schwartz, David A DA; Rotter, Jerome I JI; Roden, Daniel D; Redline, Susan S; Raby, Benjamin A BA; Psaty, Bruce M BM; Peralta, Juan M JM; Palmer, Nicholette D ND; Nekhai, Sergei S; Montgomery, Courtney G CG; Mitchell, Braxton D BD; Meyers, Deborah A DA; McGarvey, Stephen T ST; , ; Mak, Angel Cy AC; Loos, Ruth Jf RJ; Kumar, Rajesh R; Kooperberg, Charles C; Konkle, Barbara A BA; Kelly, Shannon S; Kardia, Sharon Lr SL; Kaplan, Robert R; He, Jiang J; Gui, Hongsheng H; Gilliland, Frank D FD; Gelb, Bruce D BD; Fornage, Myriam M; Ellinor, Patrick T PT; de Andrade, Mariza M; Correa, Adolfo A; Chen, Yii-Der Ida YI; Boerwinkle, Eric E; Barnes, Kathleen C KC; Ashley-Koch, Allison E AE; Arnett, Donna K DK; , ; , ; , ; Laurie, Cathy C CC; Abecasis, Goncalo G; Nickerson, Deborah A DA; Wilson, James G JG; Rich, Stephen S SS; Levy, Daniel D; Ruczinski, Ingo I; Aviv, Abraham A; Blackwell, Thomas W TW; Thornton, Timothy T; O'Connell, Jeff J; Cox, Nancy J NJ; Perry, James A JA; Armanios, Mary M; Battle, Alexis A; Pankratz, Nathan N; Reiner, Alexander P AP; Mathias, Rasika A RA
Are long telomeres better than short? Relative contributions of genetically predicted telomere length to neoplastic and non-neoplastic disease risk and population health burden.
Plos One
Protsenko, Ekaterina E; Rehkopf, David D; Prather, Aric A AA; Epel, Elissa E; Lin, Jue J
TERC Variants Associated with Short Leukocyte Telomeres: Implication of Higher Early Life Leukocyte Telomere Attrition as Assessed by the Blood-and-Muscle Model.
Cells
Toupance, Simon S; Stathopoulou, Maria G MG; Petrelis, Alexandros M AM; Gorenjak, Vesna V; Labat, Carlos C; Lai, Tsung-Po TP; Visvikis-Siest, Sophie S; Benetos, Athanase A
A genome-wide association and replication study of blood pressure in Ugandan early adolescents.
Molecular Genetics & Genomic Medicine
Lule, Swaib A SA; Mentzer, Alexander J AJ; Namara, Benigna B; Muwenzi, Allan G AG; Nassanga, Beatrice B; Kizito, Dennison D; Akurut, Helen H; Lubyayi, Lawrence L; Tumusiime, Josephine J; Zziwa, Christopher C; Akello, Florence F; Gurdasani, Deept D; Sandhu, Manjinder M; Smeeth, Liam L; Elliott, Alison M AM; Webb, Emily L EL
Al Khleifat, Ahmad A; Iacoangeli, Alfredo A; Shatunov, Aleksey A; Fang, Ton T; Sproviero, William W; Jones, Ashley R AR; Opie-Martin, Sarah S; Morrison, Karen E KE; Shaw, Pamela J PJ; Shaw, Christopher E CE; Powell, John F JF; Dobson, Richard R; Newhouse, Steven J SJ; Al-Chalabi, Ammar A
Genetic Determinants of Telomere Length in African American Youth.
Scientific Reports
Zeiger, Andrew M AM; White, Marquitta J MJ; Eng, Celeste C; Oh, Sam S SS; Witonsky, Jonathan J; Goddard, Pagé C PC; Contreras, Maria G MG; Elhawary, Jennifer R JR; Hu, Donglei D; Mak, Angel C Y ACY; Lee, Eunice Y EY; Keys, Kevin L KL; Samedy, Lesly-Anne LA; Risse-Adams, Oona O; Magaña, Joaquín J; Huntsman, Scott S; Salazar, Sandra S; Davis, Adam A; Meade, Kelley K; Brigino-Buenaventura, Emerita E; LeNoir, Michael A MA; Farber, Harold J HJ; Bibbins-Domingo, Kirsten K; Borrell, Luisa N LN; Burchard, Esteban G EG
Genome-wide association study identifies multiple risk loci for renal cell carcinoma.
Nature Communications
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Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.
Nature Genetics
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Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.
Jama Oncology
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Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.
Nature Genetics
Surendran, Praveen P; Drenos, Fotios F; Young, Robin R; Warren, Helen H; Cook, James P JP; Manning, Alisa K AK; Grarup, Niels N; Sim, Xueling X; Barnes, Daniel R DR; Witkowska, Kate K; Staley, James R JR; Tragante, Vinicius V; Tukiainen, Taru T; Yaghootkar, Hanieh H; Masca, Nicholas N; Freitag, Daniel F DF; Ferreira, Teresa T; Giannakopoulou, Olga O; Tinker, Andrew A; Harakalova, Magdalena M; Mihailov, Evelin E; Liu, Chunyu C; Kraja, Aldi T AT; Fallgaard Nielsen, Sune S; Rasheed, Asif A; Samuel, Maria M; Zhao, Wei W; Bonnycastle, Lori L LL; Jackson, Anne U AU; Narisu, Narisu N; Swift, Amy J AJ; Southam, Lorraine L; Marten, Jonathan J; Huyghe, Jeroen R JR; Stančáková, Alena A; Fava, Cristiano C; Ohlsson, Therese T; Matchan, Angela A; Stirrups, Kathleen E KE; Bork-Jensen, Jette J; Gjesing, Anette P AP; Kontto, Jukka J; Perola, Markus M; Shaw-Hawkins, Susan S; Havulinna, Aki S AS; Zhang, He H; Donnelly, Louise A LA; Groves, Christopher J CJ; Rayner, N William NW; Neville, Matt J MJ; Robertson, Neil R NR; Yiorkas, Andrianos M AM; Herzig, Karl-Heinz KH; Kajantie, Eero E; Zhang, Weihua W; Willems, Sara M SM; Lannfelt, Lars L; Malerba, Giovanni G; Soranzo, Nicole N; Trabetti, Elisabetta E; Verweij, Niek N; Evangelou, Evangelos E; Moayyeri, Alireza A; Vergnaud, Anne-Claire AC; Nelson, Christopher P CP; Poveda, Alaitz A; Varga, Tibor V TV; Caslake, Muriel M; de Craen, Anton Jm AJ; Trompet, Stella S; Luan, Jian'an J; Scott, Robert A RA; Harris, Sarah E SE; Liewald, David Cm DC; Marioni, Riccardo R; Menni, Cristina C; Farmaki, Aliki-Eleni AE; Hallmans, Göran G; Renström, Frida F; Huffman, Jennifer E JE; Hassinen, Maija M; Burgess, Stephen S; Vasan, Ramachandran S RS; Felix, Janine F JF; , ; Uria-Nickelsen, Maria M; Malarstig, Anders A; Reily, Dermot F DF; Hoek, Maarten M; Vogt, Thomas T; Lin, Honghuang H; Lieb, Wolfgang W; , ; Traylor, Matthew M; Markus, Hugh F HF; , ; Highland, Heather M HM; Justice, Anne E AE; Marouli, Eirini E; , ; Lindström, Jaana J; Uusitupa, Matti M; Komulainen, Pirjo P; Lakka, Timo A TA; Rauramaa, Rainer R; Polasek, Ozren O; Rudan, Igor I; Rolandsson, Olov O; Franks, Paul W PW; Dedoussis, George G; Spector, Timothy D TD; , ; Jousilahti, Pekka P; Männistö, Satu S; Deary, Ian J IJ; Starr, John M JM; Langenberg, Claudia C; Wareham, Nick J NJ; Brown, Morris J MJ; Dominiczak, Anna F AF; Connell, John M JM; Jukema, J Wouter JW; Sattar, Naveed N; Ford, Ian I; Packard, Chris J CJ; Esko, Tõnu T; Mägi, Reedik R; Metspalu, Andres A; de Boer, Rudolf A RA; van der Meer, Peter P; van der Harst, Pim P; , ; Gambaro, Giovanni G; Ingelsson, Erik E; Lind, Lars L; de Bakker, Paul Iw PI; Numans, Mattijs E ME; Brandslund, Ivan I; Christensen, Cramer C; Petersen, Eva Rb ER; Korpi-Hyövälti, Eeva E; Oksa, Heikki H; Chambers, John C JC; Kooner, Jaspal S JS; Blakemore, Alexandra If AI; Franks, Steve S; Jarvelin, Marjo-Riitta MR; Husemoen, Lise L LL; Linneberg, Allan A; Skaaby, Tea T; Thuesen, Betina B; Karpe, Fredrik F; Tuomilehto, Jaakko J; Doney, Alex Sf AS; Morris, Andrew D AD; Palmer, Colin Na CN; Holmen, Oddgeir Lingaas OL; Hveem, Kristian K; Willer, Cristen J CJ; Tuomi, Tiinamaija T; Groop, Leif L; Käräjämäki, AnneMari A; Palotie, Aarno A; Ripatti, Samuli S; Salomaa, Veikko V; Alam, Dewan S DS; Shafi Majumder, Abdulla Al AA; Di Angelantonio, Emanuele E; Chowdhury, Rajiv R; McCarthy, Mark I MI; Poulter, Neil N; Stanton, Alice V AV; Sever, Peter P; Amouyel, Philippe P; Arveiler, Dominique D; Blankenberg, Stefan S; Ferrières, Jean J; Kee, Frank F; Kuulasmaa, Kari K; Müller-Nurasyid, Martina M; Veronesi, Giovanni G; Virtamo, Jarmo J; Deloukas, Panos P; , ; Elliott, Paul P; , ; Zeggini, Eleftheria E; Kathiresan, Sekar S; Melander, Olle O; Kuusisto, Johanna J; Laakso, Markku M; Padmanabhan, Sandosh S; Porteous, David D; Hayward, Caroline C; Scotland, Generation G; Collins, Francis S FS; Mohlke, Karen L KL; Hansen, Torben T; Pedersen, Oluf O; Boehnke, Michael M; Stringham, Heather M HM; , ; Frossard, Philippe P; Newton-Cheh, Christopher C; , ; Tobin, Martin D MD; Nordestgaard, Børge Grønne BG; , ; , ; , ; , ; Caulfield, Mark J MJ; Mahajan, Anubha A; Morris, Andrew P AP; Tomaszewski, Maciej M; Samani, Nilesh J NJ; Saleheen, Danish D; Asselbergs, Folkert W FW; Lindgren, Cecilia M CM; Danesh, John J; Wain, Louise V LV; Butterworth, Adam S AS; Howson, Joanna Mm JM; Munroe, Patricia B PB
Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma.
Nature Communications
Chahal, Harvind S HS; Wu, Wenting W; Ransohoff, Katherine J KJ; Yang, Lingyao L; Hedlin, Haley H; Desai, Manisha M; Lin, Yuan Y; Dai, Hong-Ji HJ; Qureshi, Abrar A AA; Li, Wen-Qing WQ; Kraft, Peter P; Hinds, David A DA; Tang, Jean Y JY; Han, Jiali J; Sarin, Kavita Y KY
Association of TERC and OBFC1 haplotypes with mean leukocyte telomere length and risk for coronary heart disease.
Plos One
Maubaret, Cécilia G CG; Salpea, Klelia D KD; Romanoski, Casey E CE; Folkersen, Lasse L; Cooper, Jackie A JA; Stephanou, Coralea C; Li, Ka Wah KW; Palmen, Jutta J; Hamsten, Anders A; Neil, Andrew A; Stephens, Jeffrey W JW; Lusis, Aldons J AJ; Eriksson, Per P; Talmud, Philippa J PJ; Humphries, Steve E SE; , ; ,
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.
Nature Genetics
Bojesen, Stig E SE; Pooley, Karen A KA; Johnatty, Sharon E SE; Beesley, Jonathan J; Michailidou, Kyriaki K; Tyrer, Jonathan P JP; Edwards, Stacey L SL; Pickett, Hilda A HA; Shen, Howard C HC; Smart, Chanel E CE; Hillman, Kristine M KM; Mai, Phuong L PL; Lawrenson, Kate K; Stutz, Michael D MD; Lu, Yi Y; Karevan, Rod R; Woods, Nicholas N; Johnston, Rebecca L RL; French, Juliet D JD; Chen, Xiaoqing X; Weischer, Maren M; Nielsen, Sune F SF; Maranian, Melanie J MJ; Ghoussaini, Maya M; Ahmed, Shahana S; Baynes, Caroline C; Bolla, Manjeet K MK; Wang, Qin Q; Dennis, Joe J; McGuffog, Lesley L; Barrowdale, Daniel D; Lee, Andrew A; Healey, Sue S; Lush, Michael M; Tessier, Daniel C DC; Vincent, Daniel D; Bacot, Françis F; , ; , ; , ; , ; , ; , ; , ; , ; Vergote, Ignace I; Lambrechts, Sandrina S; Despierre, Evelyn E; Risch, Harvey A HA; González-Neira, Anna A; Rossing, Mary Anne MA; Pita, Guillermo G; Doherty, Jennifer A JA; Alvarez, Nuria N; Larson, Melissa C MC; Fridley, Brooke L BL; Schoof, Nils N; 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Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans.
Human Molecular Genetics
Mangino, Massimo M; Hwang, Shih-Jen SJ; Spector, Timothy D TD; Hunt, Steven C SC; Kimura, Masayuki M; Fitzpatrick, Annette L AL; Christiansen, Lene L; Petersen, Inge I; Elbers, Clara C CC; Harris, Tamara T; Chen, Wei W; Srinivasan, Sathanur R SR; Kark, Jeremy D JD; Benetos, Athanase A; El Shamieh, Said S; Visvikis-Siest, Sophie S; Christensen, Kaare K; Berenson, Gerald S GS; Valdes, Ana M AM; Viñuela, Ana A; Garcia, Melissa M; Arnett, Donna K DK; Broeckel, Ulrich U; Province, Michael A MA; Pankow, James S JS; Kammerer, Candace C; Liu, Yongmei Y; Nalls, Michael M; Tishkoff, Sarah S; Thomas, Fridtjof F; Ziv, Elad E; Psaty, Bruce M BM; Bis, Joshua C JC; Rotter, Jerome I JI; Taylor, Kent D KD; Smith, Erin E; Schork, Nicholas J NJ; Levy, Daniel D; Aviv, Abraham A
A prospective study of leukocyte telomere length and risk of type 2 diabetes in postmenopausal women.
Diabetes
You, Nai-Chieh Y NC; Chen, Brian H BH; Song, Yiqing Y; Lu, XuYang X; Chen, Yilin Y; Manson, JoAnn E JE; Kang, Mo M; Howard, Barbara V BV; Margolis, Karen L KL; Curb, J David JD; Phillips, Lawrence S LS; Stefanick, Marcia L ML; Tinker, Lesley F LF; Liu, Simin S
Telomere-associated polymorphisms correlate with cardiovascular disease mortality in Caucasian women: the Cardiovascular Health Study.
Mechanisms Of Ageing And Development
Burnett-Hartman, Andrea N AN; Fitzpatrick, Annette L AL; Kronmal, Richard A RA; Psaty, Bruce M BM; Jenny, Nancy S NS; Bis, Josh C JC; Tracy, Russ P RP; Kimura, Masayuki M; Aviv, Abraham A
Genome-wide association study of relative telomere length.
Plos One
Prescott, Jennifer J; Kraft, Peter P; Chasman, Daniel I DI; Savage, Sharon A SA; Mirabello, Lisa L; Berndt, Sonja I SI; Weissfeld, Joel L JL; Han, Jiali J; Hayes, Richard B RB; Chanock, Stephen J SJ; Hunter, David J DJ; De Vivo, Immaculata I
A genome-wide association study identifies a locus on chromosome 14q21 as a predictor of leukocyte telomere length and as a marker of susceptibility for bladder cancer.
Cancer Prevention Research (Philadelphia, Pa.)
Gu, Jian J; Chen, Meng M; Shete, Sanjay S; Amos, Christopher I CI; Kamat, Ashish A; Ye, Yuanqing Y; Lin, Jie J; Dinney, Colin P CP; Wu, Xifeng X
Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Levy, Daniel D; Neuhausen, Susan L SL; Hunt, Steven C SC; Kimura, Masayuki M; Hwang, Shih-Jen SJ; Chen, Wei W; Bis, Joshua C JC; Fitzpatrick, Annette L AL; Smith, Erin E; Johnson, Andrew D AD; Gardner, Jeffrey P JP; Srinivasan, Sathanur R SR; Schork, Nicholas N; Rotter, Jerome I JI; Herbig, Utz U; Psaty, Bruce M BM; Sastrasinh, Malinee M; Murray, Sarah S SS; Vasan, Ramachandran S RS; Province, Michael A MA; Glazer, Nicole L NL; Lu, Xiaobin X; Cao, Xiaojian X; Kronmal, Richard R; Mangino, Massimo M; Soranzo, Nicole N; Spector, Tim D TD; Berenson, Gerald S GS; Aviv, Abraham A