Publications:

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Obesity, clinical, and genetic predictors for glycemic progression in Chinese patients with type 2 diabetes: A cohort study using the Hong Kong Diabetes Register and Hong Kong Diabetes Biobank.

Plos Medicine

G Jiang, AO Luk, CHT Tam, ES Lau, R Ozaki, EYK Chow, APS Kong, CKP Lim, KF Lee, SC Siu, G Hui, CC Tsang, KP Lau, JYY Leung, MW Tsang, G Kam, IT Lau, JK Li, VT Yeung, E Lau, S Lo, SKS Fung, YL Cheng, CC Chow, ER Pearson, WY So, JCN Chan, RCW Ma, ,

Publication Date: 2020-07

Variant appearance in text: N/A

PMID: 32722720

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Altered Metabolome of Lipids and Amino Acids Species: A Source of Early Signature Biomarkers of T2DM.

Journal Of Clinical Medicine

A Hameed, P Mojsak, A Buczynska, HAR Suleria, A Kretowski, M Ciborowski

Publication Date: 2020-07-16

Variant appearance in text: rs7903146

PMID: 32708684

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Genetic architecture of complex traits and disease risk predictors.

Scientific Reports

SY Yong, TG Raben, L Lello, SDH Hsu

Publication Date: 2020-07-21

Variant appearance in text: N/A

PMID: 32694572

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Heritability and Genetics of Type 2 Diabetes Mellitus in Sub-Saharan Africa: A Systematic Review and Meta-Analysis.

Journal Of Diabetes Research

EA Asamoah, C Obirikorang, E Acheampong, ME Annani-Akollor, EF Laing, EW Owiredu, EO Anto

Publication Date: 2020

Variant appearance in text: N/A

PMID: 32685554

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The Mechanism of Metabolic Influences on the Endogenous GLP-1 by Oral Antidiabetic Medications in Type 2 Diabetes Mellitus.

Journal Of Diabetes Research

T Nguyen, M Gong, S Wen, X Yuan, C Wang, J Jin, L Zhou

Publication Date: 2020

Variant appearance in text: rs7903146

PMID: 32656265

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TCF7L2 rs290487 C allele aberrantly enhances hepatic gluconeogenesis through allele-specific changes in transcription and chromatin binding.

Aging

X Zhang, P Ye, H Huang, B Wang, F Dong, Q Ling

Publication Date: 2020-07-10

Variant appearance in text: rs7903146

PMID: 32651957

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Interaction between Metabolic Genetic Risk Score and Dietary Fatty Acid Intake on Central Obesity in a Ghanaian Population.

Nutrients

S Alsulami, DA Nyakotey, K Dudek, AM Bawah, JA Lovegrove, RA Annan, B Ellahi, KS Vimaleswaran

Publication Date: 2020-06-27

Variant appearance in text: N/A

PMID: 32605047

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Variations in the Wnt/β-Catenin Pathway Key Genes as Predictors of Cervical Cancer Susceptibility.

Pharmacogenomics And Personalized Medicine

B Wang, M Wang, X Li, M Yang, L Liu

Publication Date: 2020

Variant appearance in text: N/A

PMID: 32547159

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Science and Healthy Meals in the World: Nutritional Epigenomics and Nutrigenetics of the Mediterranean Diet.

Nutrients

F Caradonna, O Consiglio, C Luparello, C Gentile

Publication Date: 2020-06-11

Variant appearance in text: N/A

PMID: 32545252

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Unique insights from ClinicalTrials.gov by mining protein mutations and RSids in addition to applying the Human Phenotype Ontology.

Plos One

S Alag

Publication Date: 2020

Variant appearance in text: rs7903146

PMID: 32459809

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Is Extra Virgin Olive Oil an Ally for Women's and Men's Cardiovascular Health?

Cardiovascular Therapeutics

F Franconi, I Campesi, A Romani

Publication Date: 2020

Variant appearance in text: rs7903146

PMID: 32454893

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The Q223R Polymorphism of the Leptin Receptor Gene as a Predictor of Weight Gain in Childhood Obesity and the Identification of Possible Factors Involved.

Genes

H Marcos-Pasero, E Aguilar-Aguilar, G Colmenarejo, A Ramírez de Molina, G Reglero, V Loria-Kohen

Publication Date: 2020-05-17

Variant appearance in text: rs7903146

PMID: 32429577

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A Nutrigenetic Approach to Investigate the Relationship between Metabolic Traits and Vitamin D Status in an Asian Indian Population.

Nutrients

BE Alathari, D Bodhini, R Jayashri, N Lakshmipriya, CS Shanthi Rani, V Sudha, JA Lovegrove, RM Anjana, V Mohan, V Radha, R Pradeepa, KS Vimaleswaran

Publication Date: 2020-05-09

Variant appearance in text: N/A

PMID: 32397403

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Circulating Protein Signatures and Causal Candidates for Type 2 Diabetes.

Diabetes

V Gudmundsdottir, SB Zaghlool, V Emilsson, T Aspelund, M Ilkov, EF Gudmundsson, SM Jonsson, NR Zilhão, JR Lamb, K Suhre, LL Jennings, V Gudnason

Publication Date: 2020-05-08

Variant appearance in text: rs7903146

PMID: 32385057

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Pyrosequencing analysis of IRS1 methylation levels in schizophrenia with tardive dyskinesia.

Molecular Medicine Reports

Y Li, K Wang, P Zhang, J Huang, Y Liu, Z Wang, Y Lu, S Tan, F Yang, Y Tan

Publication Date: 2020-02-12

Variant appearance in text: rs7903146

PMID: 32319643

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The impact of phenotype, ethnicity and genotype on progression of type 2 diabetes mellitus.

Endocrinology, Diabetes & Metabolism

A Thakarakkattil Narayanan Nair, LA Donnelly, AY Dawed, S Gan, RM Anjana, M Viswanathan, CNA Palmer, ER Pearson

Publication Date: 2020-04

Variant appearance in text: N/A

PMID: 32318630

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Genes and Diet in the Prevention of Chronic Diseases in Future Generations.

International Journal Of Molecular Sciences

M Franzago, D Santurbano, E Vitacolonna, L Stuppia

Publication Date: 2020-04-10

Variant appearance in text: rs7903146

PMID: 32290086

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SLC30A8, CDKAL1, TCF7L2, KCNQ1 and IGF2BP2 are Associated with Type 2 Diabetes Mellitus in Iranian Patients.

Diabetes, Metabolic Syndrome And Obesity : Targets And Therapy

K Vatankhah Yazdi, SM Kalantar, M Houshmand, M Rahmanian, MR Manaviat, MR Jahani, B Kamalidehghan, A Almasi-Hashiani

Publication Date: 2020

Variant appearance in text: N/A

PMID: 32273741

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Diabetes as a risk factor for Alzheimer's disease in the Middle East and its shared pathological mediators.

Saudi Journal Of Biological Sciences

RL Jayaraj, S Azimullah, R Beiram

Publication Date: 2020-02

Variant appearance in text: N/A

PMID: 32210695

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Diabetes-associated genetic variation in TCF7L2 alters pulsatile insulin secretion in humans.

Jci Insight

MC Laurenti, C Dalla Man, RT Varghese, JC Andrews, RA Rizza, A Matveyenko, G De Nicolao, C Cobelli, A Vella

Publication Date: 2020-03-17

Variant appearance in text: rs7903146

PMID: 32182220

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Association between the UBE2Z rs46522 and TCF7L2 rs7903146 polymorphisms with type 2 diabetes in south western Iran.

African Health Sciences

AM Foroughmand, S Shafidelpour, M Zakerkish, MP Borujeni

Publication Date: 2019-09

Variant appearance in text: rs7903146

PMID: 32127821

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Quantile-dependent expressivity of postprandial lipemia.

Plos One

PT Williams

Publication Date: 2020

Variant appearance in text: N/A

PMID: 32101585

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Waist circumference increases risk of coronary heart disease: Evidence from a Mendelian randomization study.

Molecular Genetics & Genomic Medicine

Q Chen, L Li, J Yi, K Huang, R Shen, R Wu, C Yao

Publication Date: 2020-02-24

Variant appearance in text: N/A

PMID: 32090477

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Wnt Pathway Gene Expression Is Associated With Arterial Stiffness.

Journal Of The American Heart Association

AL Kuipers, I Miljkovic, E Barinas-Mitchell, CS Nestlerode, RK Cvejkus, VW Wheeler, Y Zhang, JM Zmuda

Publication Date: 2020-02-04

Variant appearance in text: rs7903146

PMID: 32013702

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Causal relationships between lipid and glycemic levels in an Indian population: A bidirectional Mendelian randomization approach.

Plos One

T Agarwal, T Lyngdoh, F Dudbridge, GR Chandak, S Kinra, D Prabhakaran, KS Reddy, CL Relton, G Davey Smith, S Ebrahim, V Gupta, GK Walia

Publication Date: 2020

Variant appearance in text: N/A

PMID: 31995593

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Deep learning models predict regulatory variants in pancreatic islets and refine type 2 diabetes association signals.

Elife

A Wesolowska-Andersen, G Zhuo Yu, V Nylander, F Abaitua, M Thurner, JM Torres, A Mahajan, AL Gloyn, MI McCarthy

Publication Date: 2020-01-27

Variant appearance in text: rs7903146

PMID: 31985400

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Contribution of Known Genetic Risk Variants to Dyslipidemias and Type 2 Diabetes in Mexico: A Population-Based Nationwide Study.

Genes

A Huerta-Chagoya, H Moreno-Macías, M Sevilla-González, R Rodríguez-Guillén, ML Ordóñez-Sánchez, D Gómez-Velasco, L Muñóz-Hernández, Y Segura-Kato, O Arellano-Campos, I Cruz-Bautista, CA Aguilar-Salinas, T Tusié-Luna

Publication Date: 2020-01-20

Variant appearance in text: N/A

PMID: 31968565

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Type 2 Diabetes-Associated Genetic Polymorphisms as Potential Disease Predictors.

Diabetes, Metabolic Syndrome And Obesity : Targets And Therapy

BZ Witka, DJ Oktaviani, M Marcellino, MI Barliana, R Abdulah

Publication Date: 2019

Variant appearance in text: N/A

PMID: 31908510

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A nutrigenetic approach for investigating the relationship between vitamin B12 status and metabolic traits in Indonesian women.

Journal Of Diabetes And Metabolic Disorders

S Surendran, AS Aji, U Ariyasra, SR Sari, SG Malik, N Tasrif, FF Yani, JA Lovegrove, IR Sudji, NI Lipoeto, KS Vimaleswaran

Publication Date: 2019-12

Variant appearance in text: N/A

PMID: 31890664

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Interplay of an Obesity-Based Genetic Risk Score with Dietary and Endocrine Factors on Insulin Resistance.

Nutrients

O Ramos-Lopez, JI Riezu-Boj, FI Milagro, M Cuervo, L Goni, JA Martinez

Publication Date: 2019-12-21

Variant appearance in text: N/A

PMID: 31877696

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Data on a genome-wide association study of type 2 diabetes in a Maya population.

Data In Brief

A Totomoch-Serra, MG Domínguez-Cruz, ML Muñoz, MG García-Escalante, J Burgueño, Á Díaz-Badillo, N Valadez-González, DP Escalante

Publication Date: 2020-02

Variant appearance in text: N/A

PMID: 31872004

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A diabetes-associated genetic variant is associated with diastolic dysfunction and cardiovascular disease.

Esc Heart Failure

J Molvin, A Jujic, PM Nilsson, M Leosdottir, U Lindblad, B Daka, L Bennet, L Råstam, V Lyssenko, M Magnusson

Publication Date: 2019-12-20

Variant appearance in text: N/A

PMID: 31860786

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A Systematic Review of Childhood Diabetes Research in the Middle East Region.

Frontiers In Endocrinology

S Saraswathi, S Al-Khawaga, N Elkum, K Hussain

Publication Date: 2019

Variant appearance in text: rs7903146

PMID: 31824422

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Assessing the performance of genome-wide association studies for predicting disease risk.

Plos One

J Patron, A Serra-Cayuela, B Han, C Li, DS Wishart

Publication Date: 2019

Variant appearance in text: N/A

PMID: 31805043

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The Mediterranean diet reduces the genetic risk of chromosome 9p21 for myocardial infarction in an Asian population community cohort.

Scientific Reports

HB Leu, CM Chung, JW Chen, WH Pan

Publication Date: 2019-12-05

Variant appearance in text: rs7903146

PMID: 31804579

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Glucagon-like peptide 1 (GLP-1).

Molecular Metabolism

TD Müller, B Finan, SR Bloom, D D'Alessio, DJ Drucker, PR Flatt, A Fritsche, F Gribble, HJ Grill, JF Habener, JJ Holst, W Langhans, JJ Meier, MA Nauck, D Perez-Tilve, A Pocai, F Reimann, DA Sandoval, TW Schwartz, RJ Seeley, K Stemmer, M Tang-Christensen, SC Woods, RD DiMarchi, MH Tschöp

Publication Date: 2019-12

Variant appearance in text: rs7903146

PMID: 31767182

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Pancreatic Islet Transcriptional Enhancers and Diabetes.

Current Diabetes Reports

I Cebola

Publication Date: 2019-11-21

Variant appearance in text: N/A

PMID: 31754873

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SNP-Based Genetic Risk Score Modeling Suggests No Increased Genetic Susceptibility of the Roma Population to Type 2 Diabetes Mellitus.

Genes

NA Werissa, P Piko, S Fiatal, Z Kosa, J Sandor, R Adany

Publication Date: 2019-11-19

Variant appearance in text: N/A

PMID: 31752367

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Evaluation of Single-Nucleotide Polymorphisms of Transcription Factor 7-Like 2 and ATP2B1 Genes as Cardiovascular Risk Predictors in Chronic Kidney Disease.

International Journal Of Applied & Basic Medical Research

S Kulkarni, M Lenin, R Ramesh, SCW Delphine, K Velu

Publication Date: 2019

Variant appearance in text: rs7903146

PMID: 31681547

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The DisGeNET knowledge platform for disease genomics: 2019 update.

Nucleic Acids Research

J Piñero, JM Ramírez-Anguita, J Saüch-Pitarch, F Ronzano, E Centeno, F Sanz, LI Furlong

Publication Date: 2019-11-04

Variant appearance in text: rs7903146

PMID: 31680165

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TCF7L2 polymorphisms are associated with amygdalar volume in elderly individuals with Type 2 Diabetes.

Scientific Reports

I Ganmore, A Livny, R Ravona-Springer, I Cooper, A Alkelai, S Shelly, G Tsarfaty, A Heymann, M Schnaider Beeri, L Greenbaum

Publication Date: 2019-11-01

Variant appearance in text: N/A

PMID: 31676834

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Validation of Identified Susceptible Gene Variants for New-Onset Diabetes in Renal Transplant Recipients.

Journal Of Clinical Medicine

HS Hwang, KW Hong, JS Kim, YG Kim, JY Moon, KH Jeong, SH Lee,

Publication Date: 2019-10-16

Variant appearance in text: N/A

PMID: 31623129

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Introducing the first whole genomes of nationals from the United Arab Emirates.

Scientific Reports

HS AlSafar, M Al-Ali, GD Elbait, MH Al-Maini, D Ruta, B Peramo, A Henschel, GK Tay

Publication Date: 2019-10-11

Variant appearance in text: N/A

PMID: 31604968

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Genetic predisposition to type 2 diabetes is associated with severity of coronary artery disease in patients with acute coronary syndromes.

Cardiovascular Diabetology

Q Zheng, J Jiang, Y Huo, D Chen

Publication Date: 2019-10-08

Variant appearance in text: N/A

PMID: 31594547

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Gene-diet quality interactions on haemoglobin A1c and type 2 diabetes risk: The Airwave Health Monitoring Study.

Endocrinology, Diabetes & Metabolism

R Eriksen, R Gibson, M Aresu, A Heard, Q Chan, E Evangelou, H Gao, P Elliott, G Frost

Publication Date: 2019-10

Variant appearance in text: N/A

PMID: 31592155

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The developmental Wnt signaling pathway effector β-catenin/TCF mediates hepatic functions of the sex hormone estradiol in regulating lipid metabolism.

Plos Biology

L Tian, W Shao, W Ip, Z Song, Y Badakhshi, T Jin

Publication Date: 2019-10

Variant appearance in text: rs7903146

PMID: 31589598

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Comment on: "Gene-Diet Interactions in Type 2 Diabetes: The Chicken and Egg Debate".

International Journal Of Molecular Sciences

D Onur Cura

Publication Date: 2019-10-01

Variant appearance in text: N/A

PMID: 31581435

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Genetics of diabetic neuropathy: Systematic review, meta-analysis and trial sequential analysis.

Annals Of Clinical And Translational Neurology

Y Zhao, R Zhu, D Wang, X Liu

Publication Date: 2019-10

Variant appearance in text: N/A

PMID: 31557408

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Metabolic and Vascular Effect of the Mediterranean Diet.

International Journal Of Molecular Sciences

A Tuttolomondo, I Simonetta, M Daidone, A Mogavero, A Ortello, A Pinto

Publication Date: 2019-09-23

Variant appearance in text: rs7903146

PMID: 31547615

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Common Variants in 22 Genes Regulate Response to Metformin Intervention in Children with Obesity: A Pharmacogenetic Study of a Randomized Controlled Trial.

Journal Of Clinical Medicine

A Anguita-Ruiz, B Pastor-Villaescusa, R Leis, G Bueno, R Hoyos, R Vázquez-Cobela, M Latorre-Millán, MD Cañete, J Caballero-Villarraso, Á Gil, R Cañete, CM Aguilera

Publication Date: 2019-09-16

Variant appearance in text: N/A

PMID: 31527397

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Sex-specific Mendelian randomization study of genetically predicted insulin and cardiovascular events in the UK Biobank.

Communications Biology

JV Zhao, S Luo, CM Schooling

Publication Date: 2019

Variant appearance in text: N/A

PMID: 31508506

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(Epi)genomic heterogeneity of pancreatic islet function and failure in type 2 diabetes.

Molecular Metabolism

N Lawlor, ML Stitzel

Publication Date: 2019-09

Variant appearance in text: rs7903146

PMID: 31500827

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Evaluation of Angiotensinogen M235T and T174M Polymorphisms, Demographic and Clinical Factors in New-Onset Diabetes after Liver Transplantation in Iranian Patients.

International Journal Of Organ Transplantation Medicine

S Mottaghi, N Azarpira, A Dehshahri, B Khalvati, S Namazi

Publication Date: 2019

Variant appearance in text: N/A

PMID: 31497276

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Serotonin is elevated in risk-genotype carriers of TCF7L2 - rs7903146.

Scientific Reports

A Leiherer, A Muendlein, CH Saely, P Fraunberger, H Drexel

Publication Date: 2019-09-06

Variant appearance in text: rs7903146

PMID: 31492908

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Improvement of Lipoprotein Profile and Metabolic Endotoxemia by a Lifestyle Intervention That Modifies the Gut Microbiota in Subjects With Metabolic Syndrome.

Journal Of The American Heart Association

M Guevara-Cruz, AG Flores-López, M Aguilar-López, M Sánchez-Tapia, I Medina-Vera, D Díaz, AR Tovar, N Torres

Publication Date: 2019-09-03

Variant appearance in text: N/A

PMID: 31451009

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Models Integrating Genetic and Lifestyle Interactions on Two Adiposity Phenotypes for Personalized Prescription of Energy-Restricted Diets With Different Macronutrient Distribution.

Frontiers In Genetics

O Ramos-Lopez, JI Riezu-Boj, FI Milagro, M Cuervo, L Goni, JA Martinez

Publication Date: 2019

Variant appearance in text: N/A

PMID: 31417605

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The TCF7L2 Locus: A Genetic Window Into the Pathogenesis of Type 1 and Type 2 Diabetes.

Diabetes Care

SFA Grant

Publication Date: 2019-09

Variant appearance in text: rs7903146

PMID: 31409726

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ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response.

Nature Communications

AA Adeyemo, NA Zaghloul, G Chen, AP Doumatey, CC Leitch, TL Hostelley, JE Nesmith, J Zhou, AR Bentley, D Shriner, O Fasanmade, G Okafor, B Eghan, K Agyenim-Boateng, S Chandrasekharappa, J Adeleye, W Balogun, S Owusu, A Amoah, J Acheampong, T Johnson, J Oli, C Adebamowo, , F Collins, G Dunston, CN Rotimi

Publication Date: 2019-07-19

Variant appearance in text: N/A

PMID: 31324766

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Genetic Risk Scores for Diabetes Diagnosis and Precision Medicine.

Endocrine Reviews

MS Udler, MI McCarthy, JC Florez, A Mahajan

Publication Date: 2019-12-01

Variant appearance in text: rs7903146

PMID: 31322649

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Exploration of a diversity of computational and statistical measures of association for genome-wide genetic studies.

Biodata Mining

E Manduchi, PR Orzechowski, MD Ritchie, JH Moore

Publication Date: 2019

Variant appearance in text: N/A

PMID: 31320928

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Type 2 Diabetes: Multiple Genes, Multiple Diseases.

Current Diabetes Reports

MS Udler

Publication Date: 2019-07-10

Variant appearance in text: rs7903146

PMID: 31292748

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Genome-wide association study of peripheral artery disease in the Million Veteran Program.

Nature Medicine

D Klarin, J Lynch, K Aragam, M Chaffin, TL Assimes, J Huang, KM Lee, Q Shao, JE Huffman, P Natarajan, S Arya, A Small, YV Sun, M Vujkovic, MS Freiberg, L Wang, J Chen, D Saleheen, JS Lee, DR Miller, P Reaven, PR Alba, OV Patterson, SL DuVall, WE Boden, JA Beckman, JM Gaziano, J Concato, DJ Rader, K Cho, KM Chang, PWF Wilson, CJ O'Donnell, S Kathiresan, , PS Tsao, SM Damrauer

Publication Date: 2019-08

Variant appearance in text: N/A

PMID: 31285632

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Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes.

Nature Genetics

I Miguel-Escalada, S Bonàs-Guarch, I Cebola, J Ponsa-Cobas, J Mendieta-Esteban, G Atla, BM Javierre, DMY Rolando, I Farabella, CC Morgan, J García-Hurtado, A Beucher, I Morán, L Pasquali, M Ramos-Rodríguez, EVR Appel, A Linneberg, AP Gjesing, DR Witte, O Pedersen, N Grarup, P Ravassard, D Torrents, JM Mercader, L Piemonti, T Berney, EJP de Koning, J Kerr-Conte, F Pattou, IO Fedko, L Groop, I Prokopenko, T Hansen, MA Marti-Renom, P Fraser, J Ferrer

Publication Date: 2019-07

Variant appearance in text: rs7903146

PMID: 31253982

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Genetic and Epigenetic Studies in Diabetic Kidney Disease.

Frontiers In Genetics

HF Gu

Publication Date: 2019

Variant appearance in text: N/A

PMID: 31231424

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Wnt/β-catenin signaling in brain development and mental disorders: keeping TCF7L2 in mind.

Febs Letters

J Bem, N Brożko, C Chakraborty, MA Lipiec, K Koziński, A Nagalski, ŁM Szewczyk, MB Wiśniewska

Publication Date: 2019-07

Variant appearance in text: rs7903146

PMID: 31218672

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Insulin Resistance in Children.

Frontiers In Endocrinology

VM Tagi, C Giannini, F Chiarelli

Publication Date: 2019

Variant appearance in text: N/A

PMID: 31214120

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Association of metabolism-related genes polymorphisms with adenocarcinoma of the oesophagogastric junction: Evidence from 2261 subjects.

Journal Of Cellular Biochemistry

W Tang, J Liu, Z Zhong, H Qiu, M Kang

Publication Date: 2019-11

Variant appearance in text: N/A

PMID: 31211453

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Genes for Good: Engaging the Public in Genetics Research via Social Media.

American Journal Of Human Genetics

K Brieger, GJM Zajac, A Pandit, JR Foerster, KW Li, AC Annis, EM Schmidt, CP Clark, K McMorrow, W Zhou, J Yang, AM Kwong, AP Boughton, J Wu, C Scheller, T Parikh, A de la Vega, DM Brazel, M Frieser, G Rea-Sandin, LG Fritsche, SI Vrieze, GR Abecasis

Publication Date: 2019-07-03

Variant appearance in text: N/A

PMID: 31204010

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Association Between Premorbid Body Mass Index and Amyotrophic Lateral Sclerosis: Causal Inference Through Genetic Approaches.

Frontiers In Neurology

P Zeng, X Yu, H Xu

Publication Date: 2019

Variant appearance in text: rs7903146

PMID: 31178821

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Genome editing of human pancreatic beta cell models: problems, possibilities and outlook.

Diabetologia

D Balboa, RB Prasad, L Groop, T Otonkoski

Publication Date: 2019-08

Variant appearance in text: rs7903146

PMID: 31161346

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Interaction Between Overweight and Genotypes of HLA, TCF7L2, and FTO in Relation to the Risk of Latent Autoimmune Diabetes in Adults and Type 2 Diabetes.

The Journal Of Clinical Endocrinology And Metabolism

R Hjort, JE Löfvenborg, E Ahlqvist, L Alfredsson, T Andersson, V Grill, L Groop, EP Sørgjerd, T Tuomi, BO Åsvold, S Carlsson

Publication Date: 2019-10-01

Variant appearance in text: rs7903146

PMID: 31125083

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ATAC-seq reveals alterations in open chromatin in pancreatic islets from subjects with type 2 diabetes.

Scientific Reports

M Bysani, R Agren, C Davegårdh, P Volkov, T Rönn, P Unneberg, K Bacos, C Ling

Publication Date: 2019-05-23

Variant appearance in text: N/A

PMID: 31123324

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Effects of TCF7L2 rs7903146 variant on metformin response in patients with type 2 diabetes.

Bosnian Journal Of Basic Medical Sciences

T Dujic, T Bego, M Malenica, Z Velija-Asimi, E Ahlqvist, L Groop, ER Pearson, A Causevic, S Semiz

Publication Date: 2019-11-08

Variant appearance in text: rs7903146

PMID: 31070566

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Splice-site variant in ACSL5: a marker promoting opposing effect on cell viability and protein expression.

European Journal Of Human Genetics : Ejhg

I Pérez-Núñez, M Karaky, M Fedetz, C Barrionuevo, G Izquierdo, F Matesanz, A Alcina

Publication Date: 2019-12

Variant appearance in text: rs7903146

PMID: 31053784

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Genome-wide association study of type 2 diabetes in Africa.

Diabetologia

J Chen, M Sun, A Adeyemo, F Pirie, T Carstensen, C Pomilla, AP Doumatey, G Chen, EH Young, M Sandhu, AP Morris, I Barroso, MI McCarthy, A Mahajan, E Wheeler, CN Rotimi, AA Motala

Publication Date: 2019-07

Variant appearance in text: N/A

PMID: 31049640

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Gene Lifestyle Interactions With Relation to Obesity, Cardiometabolic, and Cardiovascular Traits Among South Asians.

Frontiers In Endocrinology

S Ahmad, SS Fatima, G Rukh, CE Smith

Publication Date: 2019

Variant appearance in text: N/A

PMID: 31024458

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New genetic characteristics of latent autoimmune diabetes in adults (LADA).

Annals Of Translational Medicine

Y Chen, G Chen

Publication Date: 2019-03

Variant appearance in text: rs7903146

PMID: 31019931

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Diabetes: Is There a Future for Pharmacogenomics Guided Treatment?

Clinical Pharmacology And Therapeutics

ER Pearson

Publication Date: 2019-08

Variant appearance in text: N/A

PMID: 31012484

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Interactions between Germline and Somatic Mutated Genes in Aggressive Prostate Cancer.

Prostate Cancer

TKK Mamidi, J Wu, C Hicks

Publication Date: 2019

Variant appearance in text: N/A

PMID: 31007957

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Targeted deletion of Tcf7l2 in adipocytes promotes adipocyte hypertrophy and impaired glucose metabolism.

Molecular Metabolism

G Geoghegan, J Simcox, MM Seldin, TJ Parnell, C Stubben, S Just, L Begaye, AJ Lusis, CJ Villanueva

Publication Date: 2019-06

Variant appearance in text: rs7903146

PMID: 30948248

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Mendelian Randomization Analysis Support Causal Associations of HbA1c with Circulating Triglyceride, Total and Low-density Lipoprotein Cholesterol in a Chinese Population.

Scientific Reports

X Jia, Y Hou, M Xu, Z Zhao, L Xuan, T Wang, M Li, Y Xu, J Lu, Y Bi, W Wang, Y Chen

Publication Date: 2019-04-02

Variant appearance in text: N/A

PMID: 30940890

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Fructose Consumption Contributes to Hyperinsulinemia in Adolescents With Obesity Through a GLP-1-Mediated Mechanism.

The Journal Of Clinical Endocrinology And Metabolism

A Galderisi, C Giannini, M Van Name, S Caprio

Publication Date: 2019-08-01

Variant appearance in text: rs7903146

PMID: 30938760

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Diabetes and cancer risk: A Mendelian randomization study.

International Journal Of Cancer

A Goto, T Yamaji, N Sawada, Y Momozawa, Y Kamatani, M Kubo, T Shimazu, M Inoue, M Noda, S Tsugane, M Iwasaki

Publication Date: 2020-02-01

Variant appearance in text: N/A

PMID: 30927373

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Current Progress in Pharmacogenetics of Second-Line Antidiabetic Medications: Towards Precision Medicine for Type 2 Diabetes.

Journal Of Clinical Medicine

CU Heo, CI Choi

Publication Date: 2019-03-21

Variant appearance in text: N/A

PMID: 30901912

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The Genetic Basis of Metabolic Disease.

Cell

I Barroso, MI McCarthy

Publication Date: 2019-03-21

Variant appearance in text: N/A

PMID: 30901536

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Age at onset of obesity, transcription factor 7-like 2 (TCF7L2) rs7903146 polymorphism, adiponectin levels and the risk of type 2 diabetes in obese patients.

Archives Of Medical Science : Ams

M Wrzosek, A Sawicka, M Wrzosek, P Piątkiewicz, M Tałałaj, G Nowicka

Publication Date: 2019-03

Variant appearance in text: rs7903146

PMID: 30899283

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Assessing the Role of 98 Established Loci for BMI in American Indians.

Obesity (Silver Spring, Md.)

YL Muller, RL Hanson, P Piaggi, P Chen, G Wiessner, C Okani, G Skelton, S Kobes, WC Hsueh, WC Knowler, C Bogardus, LJ Baier

Publication Date: 2019-05

Variant appearance in text: N/A

PMID: 30887699

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Interaction between dietary patterns and TCF7L2 polymorphisms on type 2 diabetes mellitus among Uyghur adults in Xinjiang Province, China.

Diabetes, Metabolic Syndrome And Obesity : Targets And Therapy

J Cai, Y Zhang, R Nuli, Y Zhang, M Abudusemaiti, A Kadeer, X Tian, H Xiao

Publication Date: 2019

Variant appearance in text: N/A

PMID: 30858716

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Gene x Gene Interactions Highlight the Role of Incretin Resistance for Insulin Secretion.

Frontiers In Endocrinology

BA Jaghutriz, M Heni, SZ Lutz, L Fritsche, F Machicao, H Staiger, A Peter, HU Häring, A Fritsche, R Wagner

Publication Date: 2019

Variant appearance in text: N/A

PMID: 30846969

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Intake of Red and Processed Meat, Use of Non-Steroid Anti-Inflammatory Drugs, Genetic Variants and Risk of Colorectal Cancer: A Prospective Study of the Danish "Diet, Cancer and Health" Cohort.

International Journal Of Molecular Sciences

V Andersen, U Halekoh, A Tjønneland, U Vogel, TI Kopp

Publication Date: 2019-03-05

Variant appearance in text: N/A

PMID: 30841568

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Sport Nutrigenomics: Personalized Nutrition for Athletic Performance.

Frontiers In Nutrition

NS Guest, J Horne, SM Vanderhout, A El-Sohemy

Publication Date: 2019

Variant appearance in text: N/A

PMID: 30838211

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Metabolites related to purine catabolism and risk of type 2 diabetes incidence; modifying effects of the TCF7L2-rs7903146 polymorphism.

Scientific Reports

C Papandreou, J Li, L Liang, M Bulló, Y Zheng, M Ruiz-Canela, E Yu, M Guasch-Ferré, C Razquin, C Clish, D Corella, R Estruch, E Ros, M Fitó, F Arós, L Serra-Majem, N Rosique, MA Martínez-González, FB Hu, J Salas-Salvadó

Publication Date: 2019-02-27

Variant appearance in text: rs7903146

PMID: 30814579

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Influence of obesity, parental history of diabetes, and genes in type 2 diabetes: A case-control study.

Scientific Reports

J Berumen, L Orozco, M Betancourt-Cravioto, H Gallardo, M Zulueta, L Mendizabal, L Simon, RE Benuto, E Ramírez-Campos, M Marin, E Juárez, H García-Ortiz, A Martínez-Hernández, C Venegas-Vega, J Peralta-Romero, M Cruz, R Tapia-Conyer

Publication Date: 2019-02-26

Variant appearance in text: N/A

PMID: 30808941

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Assessment of pulsatile insulin secretion derived from peripheral plasma C-peptide concentrations by nonparametric stochastic deconvolution.

American Journal Of Physiology. Endocrinology And Metabolism

MC Laurenti, A Vella, RT Varghese, JC Andrews, A Sharma, NE Kittah, RA Rizza, A Matveyenko, G De Nicolao, C Cobelli, C Dalla Man

Publication Date: 2019-05-01

Variant appearance in text: rs7903146

PMID: 30807214

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The Interaction between Genetic Polymorphisms in FTO and TCF7L2 Genes and Dietary Intake with Regard to Body Mass and Composition: An Exploratory Study.

Journal Of Personalized Medicine

L Nasreddine, R Akika, A Mailhac, H Tamim, NK Zgheib

Publication Date: 2019-02-05

Variant appearance in text: rs7903146

PMID: 30764585

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Results of the First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults further highlight the need for a novel diabetes classification system.

Annals Of Translational Medicine

T Koufakis, SN Karras, P Zebekakis, K Kotsa

Publication Date: 2018-12

Variant appearance in text: rs7903146

PMID: 30740423

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Blood-based analysis of type-2 diabetes mellitus susceptibility genes identifies specific transcript variants with deregulated expression and association with disease risk.

Scientific Reports

MI Christodoulou, M Avgeris, I Kokkinopoulou, E Maratou, P Mitrou, CK Kontos, E Pappas, E Boutati, A Scorilas, EG Fragoulis

Publication Date: 2019-02-06

Variant appearance in text: N/A

PMID: 30728419

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A PheWAS study of a large observational epidemiological cohort of African Americans from the REGARDS study.

Bmc Medical Genomics

X Zhao, X Geng, V Srinivasasainagendra, N Chaudhary, S Judd, V Wadley, OM Gutiérrez, H Wang, EM Lange, LA Lange, D Woo, FW Unverzagt, M Safford, M Cushman, N Limdi, R Quarells, DK Arnett, MR Irvin, D Zhi

Publication Date: 2019-01-31

Variant appearance in text: N/A

PMID: 30704471

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Alternative transcript annotations:

Transcript	cDNA	Protein	Consequence	Exon	Intron
ENST00000346198.4	c.291+33966C>T	-	intron_variant	-	4/6
ENST00000349937.2	c.450+33966C>T	-	intron_variant	-	4/7
ENST00000352065.5	c.382-41435C>T	-	intron_variant	-	3/14
ENST00000355717.4	c.382-41435C>T	-	intron_variant	-	3/12
ENST00000355995.4	c.450+33966C>T	-	intron_variant	-	4/14
ENST00000369395.1	c.382-41435C>T	-	intron_variant	-	3/7
ENST00000369397.4	c.382-41435C>T	-	intron_variant	-	3/13
ENST00000534894.1	c.450+33966C>T	-	intron_variant	-	4/14
ENST00000536810.1	c.450+33966C>T	-	intron_variant	-	4/13
ENST00000538897.1	c.450+33966C>T	-	intron_variant	-	4/13
ENST00000542695.1	c.-531-41435C>T	-	intron_variant	-	3/14
ENST00000543371.1	c.450+33966C>T	-	intron_variant	-	4/13
ENST00000545257.1	c.450+33966C>T	-	intron_variant	-	4/14
NM_001146274.2	c.450+33966C>T	-	intron_variant	-	4/13
NM_001146283.2	c.382-41435C>T	-	intron_variant	-	3/12
NM_001146284.2	c.382-41435C>T	-	intron_variant	-	3/12
NM_001146285.1	c.382-41435C>T	-	intron_variant	-	3/12
NM_001146286.2	c.382-41435C>T	-	intron_variant	-	3/11
NM_001198525.2	c.382-41435C>T	-	intron_variant	-	3/14
NM_001198526.2	c.382-41435C>T	-	intron_variant	-	3/12
NM_001198527.2	c.382-41435C>T	-	intron_variant	-	3/14
NM_001198528.2	c.382-41435C>T	-	intron_variant	-	3/14
NM_001198529.2	c.382-41435C>T	-	intron_variant	-	3/12
NM_001198530.1	c.381+46983C>T	-	intron_variant	-	3/10
NM_001198531.2	c.450+33966C>T	-	intron_variant	-	4/12
NM_001363501.1	c.450+33966C>T	-	intron_variant	-	4/13
NM_001367943.1	c.450+33966C>T	-	intron_variant	-	4/14
NM_030756.5	c.382-41435C>T	-	intron_variant	-	3/13