Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.
Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
BAG3: Nature's Quintessential Multi-Functional Protein Functions as a Ubiquitous Intra-Cellular Glue.
Cells
Brenner, Caitlyn M CM; Choudhary, Muaaz M; McCormick, Michael G MG; Cheung, David D; Landesberg, Gavin P GP; Wang, Ju-Fang JF; Song, Jianliang J; Martin, Thomas G TG; Cheung, Joseph Y JY; Qu, Hui-Qi HQ; Hakonarson, Hakon H; Feldman, Arthur M AM
Large scale genome-wide association analyses identify novel genetic loci and mechanisms in hypertrophic cardiomyopathy.
Medrxiv : The Preprint Server For Health Sciences
Tadros, Rafik R; Zheng, Sean L SL; Grace, Christopher C; Jordà, Paloma P; Francis, Catherine C; Jurgens, Sean J SJ; Thomson, Kate L KL; Harper, Andrew R AR; Ormondroyd, Elizabeth E; West, Dominique M DM; Xu, Xiao X; Theotokis, Pantazis I PI; Buchan, Rachel J RJ; McGurk, Kathryn A KA; Mazzarotto, Francesco F; Boschi, Beatrice B; Pelo, Elisabetta E; Lee, Michael M; Noseda, Michela M; Varnava, Amanda A; Vermeer, Alexa Mc AM; Walsh, Roddy R; Amin, Ahmad S AS; van Slegtenhorst, Marjon A MA; Roslin, Nicole N; Strug, Lisa J LJ; Salvi, Erika E; Lanzani, Chiara C; de Marvao, Antonio A; , ; Roberts, Jason D JD; Tremblay-Gravel, Maxime M; Giraldeau, Genevieve G; Cadrin-Tourigny, Julia J; L'Allier, Philippe L PL; Garceau, Patrick P; Talajic, Mario M; Pinto, Yigal M YM; Rakowski, Harry H; Pantazis, Antonis A; Baksi, John J; Halliday, Brian P BP; Prasad, Sanjay K SK; Barton, Paul Jr PJ; O'Regan, Declan P DP; Cook, Stuart A SA; de Boer, Rudolf A RA; Christiaans, Imke I; Michels, Michelle M; Kramer, Christopher M CM; Ho, Carolyn Y CY; Neubauer, Stefan S; , ; Matthews, Paul M PM; Wilde, Arthur A AA; Tardif, Jean-Claude JC; Olivotto, Iacopo I; Adler, Arnon A; Goel, Anuj A; Ware, James S JS; Bezzina, Connie R CR; Watkins, Hugh H
Genetic architecture of heart failure with preserved versus reduced ejection fraction.
Nature Communications
Joseph, Jacob J; Liu, Chang C; Hui, Qin Q; Aragam, Krishna K; Wang, Zeyuan Z; Charest, Brian B; Huffman, Jennifer E JE; Keaton, Jacob M JM; Edwards, Todd L TL; Demissie, Serkalem S; Djousse, Luc L; Casas, Juan P JP; Gaziano, J Michael JM; Cho, Kelly K; Wilson, Peter W F PWF; Phillips, Lawrence S LS; , ; O'Donnell, Christopher J CJ; Sun, Yan V YV
Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.
Scientific Reports
Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways.
Nature Communications
Young, William J WJ; Lahrouchi, Najim N; Isaacs, Aaron A; Duong, ThuyVy T; Foco, Luisa L; Ahmed, Farah F; Brody, Jennifer A JA; Salman, Reem R; Noordam, Raymond R; Benjamins, Jan-Walter JW; Haessler, Jeffrey J; Lyytikäinen, Leo-Pekka LP; Repetto, Linda L; Concas, Maria Pina MP; van den Berg, Marten E ME; Weiss, Stefan S; Baldassari, Antoine R AR; Bartz, Traci M TM; Cook, James P JP; Evans, Daniel S DS; Freudling, Rebecca R; Hines, Oliver O; Isaksen, Jonas L JL; Lin, Honghuang H; Mei, Hao H; Moscati, Arden A; Müller-Nurasyid, Martina M; Nursyifa, Casia C; Qian, Yong Y; Richmond, Anne A; Roselli, Carolina C; Ryan, Kathleen A KA; Tarazona-Santos, Eduardo E; Thériault, Sébastien S; van Duijvenboden, Stefan S; Warren, Helen R HR; Yao, Jie J; Raza, Dania D; Aeschbacher, Stefanie S; Ahlberg, Gustav G; Alonso, Alvaro A; Andreasen, Laura L; Bis, Joshua C JC; Boerwinkle, Eric E; Campbell, Archie A; Catamo, Eulalia E; Cocca, Massimiliano M; Cutler, Michael J MJ; Darbar, Dawood D; De Grandi, Alessandro A; De Luca, Antonio A; Ding, Jun J; Ellervik, Christina C; Ellinor, Patrick T PT; Felix, Stephan B SB; Froguel, Philippe P; Fuchsberger, Christian C; Gögele, Martin M; Graff, Claus C; Graff, Mariaelisa M; Guo, Xiuqing X; Hansen, Torben T; Heckbert, Susan R SR; Huang, Paul L PL; Huikuri, Heikki V HV; Hutri-Kähönen, Nina N; Ikram, M Arfan MA; Jackson, Rebecca D RD; Junttila, Juhani J; Kavousi, Maryam M; Kors, Jan A JA; Leal, Thiago P TP; Lemaitre, Rozenn N RN; Lin, Henry J HJ; Lind, Lars L; Linneberg, Allan A; Liu, Simin S; MacFarlane, Peter W PW; Mangino, Massimo M; Meitinger, Thomas T; Mezzavilla, Massimo M; Mishra, Pashupati P PP; Mitchell, Rebecca N RN; Mononen, Nina N; Montasser, May E ME; Morrison, Alanna C AC; Nauck, Matthias M; Nauffal, Victor V; Navarro, Pau P; Nikus, Kjell K; Pare, Guillaume G; Patton, Kristen K KK; Pelliccione, Giulia G; Pittman, Alan A; Porteous, David J DJ; Pramstaller, Peter P PP; Preuss, Michael H MH; Raitakari, Olli T OT; Reiner, Alexander P AP; Ribeiro, Antonio Luiz P ALP; Rice, Kenneth M KM; Risch, Lorenz L; Schlessinger, David D; Schotten, Ulrich U; Schurmann, Claudia C; Shen, Xia X; Shoemaker, M Benjamin MB; Sinagra, Gianfranco G; Sinner, Moritz F MF; Soliman, Elsayed Z EZ; Stoll, Monika M; Strauch, Konstantin K; Tarasov, Kirill K; Taylor, Kent D KD; Tinker, Andrew A; Trompet, Stella S; Uitterlinden, André A; Völker, Uwe U; Völzke, Henry H; Waldenberger, Melanie M; Weng, Lu-Chen LC; Whitsel, Eric A EA; Wilson, James G JG; Avery, Christy L CL; Conen, David D; Correa, Adolfo A; Cucca, Francesco F; Dörr, Marcus M; Gharib, Sina A SA; Girotto, Giorgia G; Grarup, Niels N; Hayward, Caroline C; Jamshidi, Yalda Y; Järvelin, Marjo-Riitta MR; Jukema, J Wouter JW; Kääb, Stefan S; Kähönen, Mika M; Kanters, Jørgen K JK; Kooperberg, Charles C; Lehtimäki, Terho T; Lima-Costa, Maria Fernanda MF; Liu, Yongmei Y; Loos, Ruth J F RJF; Lubitz, Steven A SA; Mook-Kanamori, Dennis O DO; Morris, Andrew P AP; O'Connell, Jeffrey R JR; Olesen, Morten Salling MS; Orini, Michele M; Padmanabhan, Sandosh S; Pattaro, Cristian C; Peters, Annette A; Psaty, Bruce M BM; Rotter, Jerome I JI; Stricker, Bruno B; van der Harst, Pim P; van Duijn, Cornelia M CM; Verweij, Niek N; Wilson, James F JF; Arking, Dan E DE; Ramirez, Julia J; Lambiase, Pier D PD; Sotoodehnia, Nona N; Mifsud, Borbala B; Newton-Cheh, Christopher C; Munroe, Patricia B PB
Genetic and environmental determinants of diastolic heart function.
Nature Cardiovascular Research
Thanaj, Marjola M; Mielke, Johanna J; McGurk, Kathryn A KA; Bai, Wenjia W; Savioli, Nicolò N; de Marvao, Antonio A; Meyer, Hannah V HV; Zeng, Lingyao L; Sohler, Florian F; Lumbers, R Thomas RT; Wilkins, Martin R MR; Ware, James S JS; Bender, Christian C; Rueckert, Daniel D; MacNamara, Aidan A; Freitag, Daniel F DF; O'Regan, Declan P DP
Prioritization of candidate genes for a South African family with Parkinson's disease using in-silico tools.
Plos One
Sebate, Boiketlo B; Cuttler, Katelyn K; Cloete, Ruben R; Britz, Marcell M; Christoffels, Alan A; Williams, Monique M; Carr, Jonathan J; Bardien, Soraya S
Publication Date: 2021
Variant appearance in text: BAG3: 451T>C; C151R; rs2234962
Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect.
Nature Genetics
Tadros, Rafik R; Francis, Catherine C; Xu, Xiao X; Vermeer, Alexa M C AMC; Harper, Andrew R AR; Huurman, Roy R; Kelu Bisabu, Ken K; Walsh, Roddy R; Hoorntje, Edgar T ET; Te Rijdt, Wouter P WP; Buchan, Rachel J RJ; van Velzen, Hannah G HG; van Slegtenhorst, Marjon A MA; Vermeulen, Jentien M JM; Offerhaus, Joost Allard JA; Bai, Wenjia W; de Marvao, Antonio A; Lahrouchi, Najim N; Beekman, Leander L; Karper, Jacco C JC; Veldink, Jan H JH; Kayvanpour, Elham E; Pantazis, Antonis A; Baksi, A John AJ; Whiffin, Nicola N; Mazzarotto, Francesco F; Sloane, Geraldine G; Suzuki, Hideaki H; Schneider-Luftman, Deborah D; Elliott, Paul P; Richard, Pascale P; Ader, Flavie F; Villard, Eric E; Lichtner, Peter P; Meitinger, Thomas T; Tanck, Michael W T MWT; van Tintelen, J Peter JP; Thain, Andrew A; McCarty, David D; Hegele, Robert A RA; Roberts, Jason D JD; Amyot, Julie J; Dubé, Marie-Pierre MP; Cadrin-Tourigny, Julia J; Giraldeau, Geneviève G; L'Allier, Philippe L PL; Garceau, Patrick P; Tardif, Jean-Claude JC; Boekholdt, S Matthijs SM; Lumbers, R Thomas RT; Asselbergs, Folkert W FW; Barton, Paul J R PJR; Cook, Stuart A SA; Prasad, Sanjay K SK; O'Regan, Declan P DP; van der Velden, Jolanda J; Verweij, Karin J H KJH; Talajic, Mario M; Lettre, Guillaume G; Pinto, Yigal M YM; Meder, Benjamin B; Charron, Philippe P; de Boer, Rudolf A RA; Christiaans, Imke I; Michels, Michelle M; Wilde, Arthur A M AAM; Watkins, Hugh H; Matthews, Paul M PM; Ware, James S JS; Bezzina, Connie R CR
Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy.
Cell
Krug, Karsten K; Jaehnig, Eric J EJ; Satpathy, Shankha S; Blumenberg, Lili L; Karpova, Alla A; Anurag, Meenakshi M; Miles, George G; Mertins, Philipp P; Geffen, Yifat Y; Tang, Lauren C LC; Heiman, David I DI; Cao, Song S; Maruvka, Yosef E YE; Lei, Jonathan T JT; Huang, Chen C; Kothadia, Ramani B RB; Colaprico, Antonio A; Birger, Chet C; Wang, Jarey J; Dou, Yongchao Y; Wen, Bo B; Shi, Zhiao Z; Liao, Yuxing Y; Wiznerowicz, Maciej M; Wyczalkowski, Matthew A MA; Chen, Xi Steven XS; Kennedy, Jacob J JJ; Paulovich, Amanda G AG; Thiagarajan, Mathangi M; Kinsinger, Christopher R CR; Hiltke, Tara T; Boja, Emily S ES; Mesri, Mehdi M; Robles, Ana I AI; Rodriguez, Henry H; Westbrook, Thomas F TF; Ding, Li L; Getz, Gad G; Clauser, Karl R KR; Fenyö, David D; Ruggles, Kelly V KV; Zhang, Bing B; Mani, D R DR; Carr, Steven A SA; Ellis, Matthew J MJ; Gillette, Michael A MA; ,
The Egyptian Collaborative Cardiac Genomics (ECCO-GEN) Project: defining a healthy volunteer cohort.
Npj Genomic Medicine
Aguib, Yasmine Y; Allouba, Mona M; Afify, Alaa A; Halawa, Sarah S; El-Khatib, Mohamed M; Sous, Marina M; Galal, Aya A; Abdelrahman, Eslam E; Shehata, Nairouz N; El Sawy, Amr A; Elmaghawry, Mohamed M; Anwer, Shehab S; Kamel, Omnia O; El Mozy, Wesam W; Khedr, Hadir H; Kharabish, Ahmed A; Thabet, Nagwa N; Theotokis, Pantazis I PI; Buchan, Rachel R; Govind, Risha R; Whiffin, Nicola N; Walsh, Roddy R; Aguib, Heba H; Elguindy, Ahmed A; O'Regan, Declan P DP; Cook, Stuart A SA; Barton, Paul J PJ; Ware, James S JS; Yacoub, Magdi M
Publication Date: 2020
Variant appearance in text: BAG3: 451T>C; Cys151Arg
Verweij, Niek N; Benjamins, Jan-Walter JW; Morley, Michael P MP; van de Vegte, Yordi J YJ; Teumer, Alexander A; Trenkwalder, Teresa T; Reinhard, Wibke W; Cappola, Thomas P TP; van der Harst, Pim P
Meta-Analysis of 26 638 Individuals Identifies Two Genetic Loci Associated With Left Ventricular Ejection Fraction.
Circulation. Genomic And Precision Medicine
Choquet, Hélène H; Thai, Khanh K KK; Jiang, Chen C; Ranatunga, Dilrini K DK; Hoffmann, Thomas J TJ; Go, Alan S AS; Lindsay, Alistair C AC; Ehm, Margaret G MG; Waterworth, Dawn M DM; Risch, Neil N; Schaefer, Catherine C
Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy.
Nature Communications
Pirruccello, James P JP; Bick, Alexander A; Wang, Minxian M; Chaffin, Mark M; Friedman, Samuel S; Yao, Jie J; Guo, Xiuqing X; Venkatesh, Bharath Ambale BA; Taylor, Kent D KD; Post, Wendy S WS; Rich, Stephen S; Lima, Joao A C JAC; Rotter, Jerome I JI; Philippakis, Anthony A; Lubitz, Steven A SA; Ellinor, Patrick T PT; Khera, Amit V AV; Kathiresan, Sekar S; Aragam, Krishna G KG
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.
Nature Communications
Shah, Sonia S; Henry, Albert A; Roselli, Carolina C; Lin, Honghuang H; Sveinbjörnsson, Garðar G; Fatemifar, Ghazaleh G; Hedman, Åsa K ÅK; Wilk, Jemma B JB; Morley, Michael P MP; Chaffin, Mark D MD; Helgadottir, Anna A; Verweij, Niek N; Dehghan, Abbas A; Almgren, Peter P; Andersson, Charlotte C; Aragam, Krishna G KG; Ärnlöv, Johan J; Backman, Joshua D JD; Biggs, Mary L ML; Bloom, Heather L HL; Brandimarto, Jeffrey J; Brown, Michael R MR; Buckbinder, Leonard L; Carey, David J DJ; Chasman, Daniel I DI; Chen, Xing X; Chen, Xu X; Chung, Jonathan J; Chutkow, William W; Cook, James P JP; Delgado, Graciela E GE; Denaxas, Spiros S; Doney, Alexander S AS; Dörr, Marcus M; Dudley, Samuel C SC; Dunn, Michael E ME; Engström, Gunnar G; Esko, Tõnu T; Felix, Stephan B SB; Finan, Chris C; Ford, Ian I; Ghanbari, Mohsen M; Ghasemi, Sahar S; Giedraitis, Vilmantas V; Giulianini, Franco F; Gottdiener, John S JS; Gross, Stefan S; Guðbjartsson, Daníel F DF; Gutmann, Rebecca R; Haggerty, Christopher M CM; van der Harst, Pim P; Hyde, Craig L CL; Ingelsson, Erik E; Jukema, J Wouter JW; Kavousi, Maryam M; Khaw, Kay-Tee KT; Kleber, Marcus E ME; Køber, Lars L; Koekemoer, Andrea A; Langenberg, Claudia C; Lind, Lars L; Lindgren, Cecilia M CM; London, Barry B; Lotta, Luca A LA; Lovering, Ruth C RC; Luan, Jian'an J; Magnusson, Patrik P; Mahajan, Anubha A; Margulies, Kenneth B KB; März, Winfried W; Melander, Olle O; Mordi, Ify R IR; Morgan, Thomas T; Morris, Andrew D AD; Morris, Andrew P AP; Morrison, Alanna C AC; Nagle, Michael W MW; Nelson, Christopher P CP; Niessner, Alexander A; Niiranen, Teemu T; O'Donoghue, Michelle L ML; Owens, Anjali T AT; Palmer, Colin N A CNA; Parry, Helen M HM; Perola, Markus M; Portilla-Fernandez, Eliana E; Psaty, Bruce M BM; , ; Rice, Kenneth M KM; Ridker, Paul M PM; Romaine, Simon P R SPR; Rotter, Jerome I JI; Salo, Perttu P; Salomaa, Veikko V; van Setten, Jessica J; Shalaby, Alaa A AA; Smelser, Diane T DT; Smith, Nicholas L NL; Stender, Steen S; Stott, David J DJ; Svensson, Per P; Tammesoo, Mari-Liis ML; Taylor, Kent D KD; Teder-Laving, Maris M; Teumer, Alexander A; Thorgeirsson, Guðmundur G; Thorsteinsdottir, Unnur U; Torp-Pedersen, Christian C; Trompet, Stella S; Tyl, Benoit B; Uitterlinden, Andre G AG; Veluchamy, Abirami A; Völker, Uwe U; Voors, Adriaan A AA; Wang, Xiaosong X; Wareham, Nicholas J NJ; Waterworth, Dawn D; Weeke, Peter E PE; Weiss, Raul R; Wiggins, Kerri L KL; Xing, Heming H; Yerges-Armstrong, Laura M LM; Yu, Bing B; Zannad, Faiez F; Zhao, Jing Hua JH; Hemingway, Harry H; Samani, Nilesh J NJ; McMurray, John J V JJV; Yang, Jian J; Visscher, Peter M PM; Newton-Cheh, Christopher C; Malarstig, Anders A; Holm, Hilma H; Lubitz, Steven A SA; Sattar, Naveed N; Holmes, Michael V MV; Cappola, Thomas P TP; Asselbergs, Folkert W FW; Hingorani, Aroon D AD; Kuchenbaecker, Karoline K; Ellinor, Patrick T PT; Lang, Chim C CC; Stefansson, Kari K; Smith, J Gustav JG; Vasan, Ramachandran S RS; Swerdlow, Daniel I DI; Lumbers, R Thomas RT
Sequence variants with large effects on cardiac electrophysiology and disease.
Nature Communications
Norland, Kristjan K; Sveinbjornsson, Gardar G; Thorolfsdottir, Rosa B RB; Davidsson, Olafur B OB; Tragante, Vinicius V; Rajamani, Sridharan S; Helgadottir, Anna A; Gretarsdottir, Solveig S; van Setten, Jessica J; Asselbergs, Folkert W FW; Sverrisson, Jon Th JT; Stephensen, Sigurdur S SS; Oskarsson, Gylfi G; Sigurdsson, Emil L EL; Andersen, Karl K; Danielsen, Ragnar R; Thorgeirsson, Gudmundur G; Thorsteinsdottir, Unnur U; Arnar, David O DO; Sulem, Patrick P; Holm, Hilma H; Gudbjartsson, Daniel F DF; Stefansson, Kari K
Publication Date: 2019-10-22
Variant appearance in text: BAG3: Cys151Arg; rs2234962
Genome-Wide Analysis of Left Ventricular Image-Derived Phenotypes Identifies Fourteen Loci Associated With Cardiac Morphogenesis and Heart Failure Development.
Circulation
Aung, Nay N; Vargas, Jose D JD; Yang, Chaojie C; Cabrera, Claudia P CP; Warren, Helen R HR; Fung, Kenneth K; Tzanis, Evan E; Barnes, Michael R MR; Rotter, Jerome I JI; Taylor, Kent D KD; Manichaikul, Ani W AW; Lima, Joao A C JAC; Bluemke, David A DA; Piechnik, Stefan K SK; Neubauer, Stefan S; Munroe, Patricia B PB; Petersen, Steffen E SE
A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.
Scientific Reports
Stringer, Brett W BW; Day, Bryan W BW; D'Souza, Rochelle C J RCJ; Jamieson, Paul R PR; Ensbey, Kathleen S KS; Bruce, Zara C ZC; Lim, Yi Chieh YC; Goasdoué, Kate K; Offenhäuser, Carolin C; Akgül, Seçkin S; Allan, Suzanne S; Robertson, Thomas T; Lucas, Peter P; Tollesson, Gert G; Campbell, Scott S; Winter, Craig C; Do, Hongdo H; Dobrovic, Alexander A; Inglis, Po-Ling PL; Jeffree, Rosalind L RL; Johns, Terrance G TG; Boyd, Andrew W AW
Publication Date: 2019-03-20
Variant appearance in text: BAG3: C151R; rs2234962
Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases.
Cell Death & Disease
Grassi, Ludovica L; Alfonsi, Romina R; Francescangeli, Federica F; Signore, Michele M; De Angelis, Maria Laura ML; Addario, Antonio A; Costantini, Manuela M; Flex, Elisabetta E; Ciolfi, Andrea A; Pizzi, Simone S; Bruselles, Alessandro A; Pallocca, Matteo M; Simone, Giuseppe G; Haoui, Mustapha M; Falchi, Mario M; Milella, Michele M; Sentinelli, Steno S; Di Matteo, Paola P; Stellacci, Emilia E; Gallucci, Michele M; Muto, Giovanni G; Tartaglia, Marco M; De Maria, Ruggero R; Bonci, Désirée D
Publication Date: 2019-02-27
Variant appearance in text: BAG3: 451T>C; Cys151Arg; rs2234962
Identifying Extrinsic versus Intrinsic Drivers of Variation in Cell Behavior in Human iPSC Lines from Healthy Donors.
Cell Reports
Vigilante, Alessandra A; Laddach, Anna A; Moens, Nathalie N; Meleckyte, Ruta R; Leha, Andreas A; Ghahramani, Arsham A; Culley, Oliver J OJ; Kathuria, Annie A; Hurling, Chloe C; Vickers, Alice A; Wiseman, Erika E; Tewary, Mukul M; Zandstra, Peter W PW; , ; Durbin, Richard R; Fraternali, Franca F; Stegle, Oliver O; Birney, Ewan E; Luscombe, Nicholas M NM; Danovi, Davide D; Watt, Fiona M FM
Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic Discovery.
Circulation
Aragam, Krishna G KG; Chaffin, Mark M; Levinson, Rebecca T RT; McDermott, Gregory G; Choi, Seung-Hoan SH; Shoemaker, M Benjamin MB; Haas, Mary E ME; Weng, Lu-Chen LC; Lindsay, Mark E ME; Smith, J Gustav JG; Newton-Cheh, Christopher C; Roden, Dan M DM; London, Barry B; Wells, Quinn S QS; Ellinor, Patrick T PT; Kathiresan, Sekar S; Lubitz, Steven A SA; ,
Association of Variants in BAG3 With Cardiomyopathy Outcomes in African American Individuals.
Jama Cardiology
Myers, Valerie D VD; Gerhard, Glenn S GS; McNamara, Dennis M DM; Tomar, Dhanendra D; Madesh, Muniswamy M; Kaniper, Scott S; Ramsey, Frederick V FV; Fisher, Susan G SG; Ingersoll, Roxann G RG; Kasch-Semenza, Laura L; Wang, JuFang J; Hanley-Yanez, Karen K; Lemster, Bonnie B; Schwisow, Jessica A JA; Ambardekar, Amrut V AV; Degann, Seta H SH; Bristow, Michael R MR; Sheppard, Richard R; Alexis, Jeffrey D JD; Tilley, Douglas G DG; Kontos, Christopher D CD; McClung, Joseph M JM; Taylor, Anne L AL; Yancy, Clyde W CW; Khalili, Kamel K; Seidman, Jonathan G JG; Seidman, Christine E CE; McTiernan, Charles F CF; Cheung, Joseph Y JY; Feldman, Arthur M AM
A Genome-Wide Association Study of Idiopathic Dilated Cardiomyopathy in African Americans.
Journal Of Personalized Medicine
Xu, Huichun H; Dorn, Gerald W GW; Shetty, Amol A; Parihar, Ankita A; Dave, Tushar T; Robinson, Shawn W SW; Gottlieb, Stephen S SS; Donahue, Mark P MP; Tomaselli, Gordon F GF; Kraus, William E WE; Mitchell, Braxton D BD; Liggett, Stephen B SB
Development and validation of a targeted next generation DNA sequencing panel outperforming whole exome sequencing for the identification of clinically relevant genetic variants.
Oncotarget
Miller, Eirwen M EM; Patterson, Nicole E NE; Zechmeister, Jenna Marcus JM; Bejerano-Sagie, Michal M; Delio, Maria M; Patel, Kunjan K; Ravi, Nivedita N; Quispe-Tintaya, Wilber W; Maslov, Alexander A; Simmons, Nichelle N; Castaldi, Maria M; Vijg, Jan J; Karabakhtsian, Rouzan G RG; Greally, John M JM; Kuo, Dennis Y S DYS; Montagna, Cristina C
Publication Date: 2017-11-24
Variant appearance in text: BAG3: C151R; rs2234962
Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy.
Plos One
Esslinger, Ulrike U; Garnier, Sophie S; Korniat, Agathe A; Proust, Carole C; Kararigas, Georgios G; Müller-Nurasyid, Martina M; Empana, Jean-Philippe JP; Morley, Michael P MP; Perret, Claire C; Stark, Klaus K; Bick, Alexander G AG; Prasad, Sanjay K SK; Kriebel, Jennifer J; Li, Jin J; Tiret, Laurence L; Strauch, Konstantin K; O'Regan, Declan P DP; Marguiles, Kenneth B KB; Seidman, Jonathan G JG; Boutouyrie, Pierre P; Lacolley, Patrick P; Jouven, Xavier X; Hengstenberg, Christian C; Komajda, Michel M; Hakonarson, Hakon H; Isnard, Richard R; Arbustini, Eloisa E; Grallert, Harald H; Cook, Stuart A SA; Seidman, Christine E CE; Regitz-Zagrosek, Vera V; Cappola, Thomas P TP; Charron, Philippe P; Cambien, François F; Villard, Eric E
Publication Date: 2017
Variant appearance in text: BAG3: 451T>C; Cys151Arg; rs2234962
Three-dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model.
The Journal Of Pathology
Maguire, Sarah L SL; Peck, Barrie B; Wai, Patty T PT; Campbell, James J; Barker, Holly H; Gulati, Aditi A; Daley, Frances F; Vyse, Simon S; Huang, Paul P; Lord, Christopher J CJ; Farnie, Gillian G; Brennan, Keith K; Natrajan, Rachael R
Publication Date: 2016-11
Variant appearance in text: BAG3: C151R; rs2234962
Proteogenomics connects somatic mutations to signalling in breast cancer.
Nature
Mertins, Philipp P; Mani, D R DR; Ruggles, Kelly V KV; Gillette, Michael A MA; Clauser, Karl R KR; Wang, Pei P; Wang, Xianlong X; Qiao, Jana W JW; Cao, Song S; Petralia, Francesca F; Kawaler, Emily E; Mundt, Filip F; Krug, Karsten K; Tu, Zhidong Z; Lei, Jonathan T JT; Gatza, Michael L ML; Wilkerson, Matthew M; Perou, Charles M CM; Yellapantula, Venkata V; Huang, Kuan-lin KL; Lin, Chenwei C; McLellan, Michael D MD; Yan, Ping P; Davies, Sherri R SR; Townsend, R Reid RR; Skates, Steven J SJ; Wang, Jing J; Zhang, Bing B; Kinsinger, Christopher R CR; Mesri, Mehdi M; Rodriguez, Henry H; Ding, Li L; Paulovich, Amanda G AG; Fenyö, David D; Ellis, Matthew J MJ; Carr, Steven A SA; ,
Publication Date: 2016-06-02
Variant appearance in text: BAG3: C151R; rs2234962
A novel miR-371a-5p-mediated pathway, leading to BAG3 upregulation in cardiomyocytes in response to epinephrine, is lost in Takotsubo cardiomyopathy.
Cell Death & Disease
d'Avenia, M M; Citro, R R; De Marco, M M; Veronese, A A; Rosati, A A; Visone, R R; Leptidis, S S; Philippen, L L; Vitale, G G; Cavallo, A A; Silverio, A A; Prota, C C; Gravina, P P; De Cola, A A; Carletti, E E; Coppola, G G; Gallo, S S; Provenza, G G; Bossone, E E; Piscione, F F; Hahne, M M; De Windt, L J LJ; Turco, M C MC; De Laurenzi, V V
Knezevic, Tijana T; Myers, Valerie D VD; Gordon, Jennifer J; Tilley, Douglas G DG; Sharp, Thomas E TE; Wang, JuFang J; Khalili, Kamel K; Cheung, Joseph Y JY; Feldman, Arthur M AM
Whole-genome sequencing of the world's oldest people.
Plos One
Gierman, Hinco J HJ; Fortney, Kristen K; Roach, Jared C JC; Coles, Natalie S NS; Li, Hong H; Glusman, Gustavo G; Markov, Glenn J GJ; Smith, Justin D JD; Hood, Leroy L; Coles, L Stephen LS; Kim, Stuart K SK
Publication Date: 2014
Variant appearance in text: BAG3: C151R; rs2234962
NCI-60 whole exome sequencing and pharmacological CellMiner analyses.
Plos One
Reinhold, William C WC; Varma, Sudhir S; Sousa, Fabricio F; Sunshine, Margot M; Abaan, Ogan D OD; Davis, Sean R SR; Reinhold, Spencer W SW; Kohn, Kurt W KW; Morris, Joel J; Meltzer, Paul S PS; Doroshow, James H JH; Pommier, Yves Y
Publication Date: 2014
Variant appearance in text: BAG3: C151R; rs2234962