Polygenic risk scores predict diabetes complications and their response to intensive blood pressure and glucose control.
Diabetologia
Tremblay, Johanne J; Haloui, Mounsif M; Attaoua, Redha R; Tahir, Ramzan R; Hishmih, Camil C; Harvey, François F; Marois-Blanchet, François-Christophe FC; Long, Carole C; Simon, Paul P; Santucci, Lara L; Hizel, Candan C; Chalmers, John J; Marre, Michel M; Harrap, Stephen S; Cífková, Renata R; Krajčoviechová, Alena A; Matthews, David R DR; Williams, Bryan B; Poulter, Neil N; Zoungas, Sophia S; Colagiuri, Stephen S; Mancia, Giuseppe G; Grobbee, Diederick E DE; Rodgers, Anthony A; Liu, Liusheng L; Agbessi, Mawussé M; Bruat, Vanessa V; Favé, Marie-Julie MJ; Harwood, Michelle P MP; Awadalla, Philip P; Woodward, Mark M; Hussin, Julie G JG; Hamet, Pavel P
A genome-wide association and replication study of blood pressure in Ugandan early adolescents.
Molecular Genetics & Genomic Medicine
Lule, Swaib A SA; Mentzer, Alexander J AJ; Namara, Benigna B; Muwenzi, Allan G AG; Nassanga, Beatrice B; Kizito, Dennison D; Akurut, Helen H; Lubyayi, Lawrence L; Tumusiime, Josephine J; Zziwa, Christopher C; Akello, Florence F; Gurdasani, Deept D; Sandhu, Manjinder M; Smeeth, Liam L; Elliott, Alison M AM; Webb, Emily L EL
Towards Precision Medicine for Hypertension: A Review of Genomic, Epigenomic, and Microbiomic Effects on Blood Pressure in Experimental Rat Models and Humans.
Genome-Wide Association Study of Blood Pressure Traits by Hispanic/Latino Background: the Hispanic Community Health Study/Study of Latinos.
Scientific Reports
Sofer, Tamar T; Wong, Quenna Q; Hartwig, Fernando P FP; Taylor, Kent K; Warren, Helen R HR; Evangelou, Evangelos E; Cabrera, Claudia P CP; Levy, Daniel D; Kramer, Holly H; Lange, Leslie A LA; Horta, Bernardo L BL; , ; Kerr, Kathleen F KF; Reiner, Alex P AP; Franceschini, Nora N
Hypertension Susceptibility Loci are Associated with Anthracycline-related Cardiotoxicity in Long-term Childhood Cancer Survivors.
Scientific Reports
Hildebrandt, Michelle A T MAT; Reyes, Monica M; Wu, Xifeng X; Pu, Xia X; Thompson, Kara A KA; Ma, Jianzhong J; Landstrom, Andrew P AP; Morrison, Alanna C AC; Ater, Joann L JL
Utility of blood pressure genetic risk score in admixed Hispanic samples.
Journal Of Human Hypertension
Beecham, A H AH; Wang, L L; Vasudeva, N N; Liu, Z Z; Dong, C C; Goldschmidt-Clermont, P J PJ; Pericak-Vance, M A MA; Rundek, T T; Seo, D D; Blanton, S H SH; Sacco, R L RL; Beecham, G W GW
Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium.
Plos One
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Sequence analysis of six blood pressure candidate regions in 4,178 individuals: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study.
Plos One
Morrison, Alanna C AC; Bis, Joshua C JC; Hwang, Shih-Jen SJ; Ehret, Georg B GB; Lumley, Thomas T; Rice, Kenneth K; Muzny, Donna D; Gibbs, Richard A RA; Boerwinkle, Eric E; Psaty, Bruce M BM; Chakravarti, Aravinda A; Levy, Daniel D
Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia.
American Journal Of Human Genetics
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Genetic influences on trajectories of systolic blood pressure across childhood and adolescence.
Circulation. Cardiovascular Genetics
Howe, Laura D LD; Parmar, Priyakumari G PG; Paternoster, Lavinia L; Warrington, Nicole M NM; Kemp, John P JP; Briollais, Laurent L; Newnham, John P JP; Timpson, Nicholas J NJ; Smith, George Davey GD; Ring, Susan M SM; Evans, David M DM; Tilling, Kate K; Pennell, Craig E CE; Beilin, Lawrie J LJ; Palmer, Lyle J LJ; Lawlor, Debbie A DA
Genome-wide meta-analysis of systolic blood pressure in children with sickle cell disease.
Plos One
Bhatnagar, Pallav P; Barron-Casella, Emily E; Bean, Christopher J CJ; Milton, Jacqueline N JN; Baldwin, Clinton T CT; Steinberg, Martin H MH; Debaun, Michael M; Casella, James F JF; Arking, Dan E DE
Gentrepid V2.0: a web server for candidate disease gene prediction.
Bmc Bioinformatics
Ballouz, Sara S; Liu, Jason Y JY; George, Richard A RA; Bains, Naresh N; Liu, Arthur A; Oti, Martin M; Gaeta, Bruno B; Fatkin, Diane D; Wouters, Merridee A MA
Overlap between common genetic polymorphisms underpinning kidney traits and cardiovascular disease phenotypes: the CKDGen consortium.
American Journal Of Kidney Diseases : The Official Journal Of The National Kidney Foundation
Olden, Matthias M; Teumer, Alexander A; Bochud, Murielle M; Pattaro, Cristian C; Köttgen, Anna A; Turner, Stephen T ST; Rettig, Rainer R; Chen, Ming-Huei MH; Dehghan, Abbas A; Bastardot, Francois F; Schmidt, Reinhold R; Vollenweider, Peter P; Schunkert, Heribert H; Reilly, Muredach P MP; Fornage, Myriam M; Launer, Lenore J LJ; Verwoert, Germaine C GC; Mitchell, Gary F GF; Bis, Joshua C JC; O'Donnell, Christopher J CJ; Cheng, Ching-Yu CY; Sim, Xueling X; Siscovick, David S DS; Coresh, Josef J; Kao, W H Linda WH; Fox, Caroline S CS; O'Seaghdha, Conall M CM; ,
Association of cardiovascular and metabolic disease genes with psoriasis.
The Journal Of Investigative Dermatology
Lu, Yingchang Y; Chen, Haoyan H; Nikamo, Pernilla P; Qi Low, Hui H; Helms, Cynthia C; Seielstad, Mark M; Liu, Jianjun J; Bowcock, Anne M AM; Stahle, Mona M; Liao, Wilson W
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
Nature
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