Publications:

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Stabilization of MYC G-quadruplex DNA by ruthenium (II) complex overcomes imatinib resistance in chronic myeloid leukemia cells harboring T315I mutation.

Genes & Diseases

Sun, Yuening Y; Chen, Xin X; Liao, Siyan S; Liu, Aochu A; Zhou, Huan H; Jiang, Liling L; Ding, Wa W; Mei, Wenjie W; Liu, Jinbao J; Shi, Xianping X

Publication Date: 2023-03

Variant appearance in text: RET: T315I

PubMed Link: 37223538

Variant Present in the following documents:

• Main text
• main.pdf

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An intuitionistic approach for the predictability of anti-angiogenic inhibitors in cancer diagnosis.

Scientific Reports

Ansar, Syed Anas SA; Aggarwal, Shruti S; Arya, Swati S; Haq, Mohd Anul MA; Mittal, Vikas V; Gared, Fikreselam F

Publication Date: 2023-04-29

Variant appearance in text: RET: t315i

PubMed Link: 37120640

Variant Present in the following documents:

• Main text
• 41598_2023_Article_32850.pdf

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Molecular Anatomy of the EML4-ALK Fusion Protein for the Development of Novel Anticancer Drugs.

International Journal Of Molecular Sciences

Cheon, So Yeong SY; Kwon, Sunghark S

Publication Date: 2023-03-18

Variant appearance in text: RET: T315I

PubMed Link: 36982897

Variant Present in the following documents:

• Main text
• ijms-24-05821.pdf

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Ponatinib-Induced Cerebrovascular Accident (CVA).

Cureus

Azad, Farhan F; Zhang, Jiahua J; Miranda, Clive J CJ; Gravina, Matthew M

Publication Date: 2022-12

Variant appearance in text: RET: T315I

PubMed Link: 36632247

Variant Present in the following documents:

• Main text
• cureus-0014-00000032383.pdf

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Design of new drugs for medullary thyroid carcinoma.

Frontiers In Oncology

Li, Yanqing Y; Luo, Ziyu Z; Wang, Xinxing X; Zhang, Songtao S; Hei, Hu H; Qin, Jianwu J

Publication Date: 2022

Variant appearance in text: RET: T315I

PubMed Link: 36544713

Variant Present in the following documents:

• fonc-12-993725.pdf

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Small molecule inhibitors targeting the cancers.

Medcomm

Liu, Gui-Hong GH; Chen, Tao T; Zhang, Xin X; Ma, Xue-Lei XL; Shi, Hua-Shan HS

Publication Date: 2022-12

Variant appearance in text: RET: T315I

PubMed Link: 36254250

Variant Present in the following documents:

• MCO2-3-e181-s003.xlsx, sheet 1

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Protein tyrosine kinase inhibitor resistance in malignant tumors: molecular mechanisms and future perspective.

Signal Transduction And Targeted Therapy

Yang, Yang Y; Li, Shuo S; Wang, Yujiao Y; Zhao, Yi Y; Li, Qiu Q

Publication Date: 2022-09-17

Variant appearance in text: RET: T315I

PubMed Link: 36115852

Variant Present in the following documents:

• Main text

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Dual-Targeted Therapy Circumvents Non-Genetic Drug Resistance to Targeted Therapy.

Frontiers In Oncology

Wang, Wei W; Sun, Yue Y; Liu, Xiaobo X; Kumar, Shaji K SK; Jin, Fengyan F; Dai, Yun Y

Publication Date: 2022

Variant appearance in text: RET: T315I

PubMed Link: 35574302

Variant Present in the following documents:

• Main text
• fonc-12-859455.pdf

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Anticancer Activity of Erianin: Cancer-Specific Target Prediction Based on Network Pharmacology.

Frontiers In Molecular Biosciences

Yan, Lili L; Zhang, Zhen Z; Liu, Yanfen Y; Ren, Shuyi S; Zhu, Zhiyu Z; Wei, Lu L; Feng, Jiao J; Duan, Ting T; Sun, Xueni X; Xie, Tian T; Sui, Xinbing X

Publication Date: 2022

Variant appearance in text: RET: T315I

PubMed Link: 35372513

Variant Present in the following documents:

• fmolb-09-862932.pdf

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Whole-genome analysis of human embryonic stem cells enables rational line selection based on genetic variation.

Cell Stem Cell

Merkle, Florian T FT; Ghosh, Sulagna S; Genovese, Giulio G; Handsaker, Robert E RE; Kashin, Seva S; Meyer, Daniel D; Karczewski, Konrad J KJ; O'Dushlaine, Colm C; Pato, Carlos C; Pato, Michele M; MacArthur, Daniel G DG; McCarroll, Steven A SA; Eggan, Kevin K

Publication Date: 2022-03-03

Variant appearance in text: RET: T315I

PubMed Link: 35176222

Variant Present in the following documents:

• mmc5.xlsx, sheet 1

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Ibrutinib-related uveitis: A case series.

American Journal Of Ophthalmology Case Reports

Chiu, Zelia K ZK; Goh, Jonathan Ks JK; Ling, Cecilia C; Lin, Ming-Lee ML; Hall, Anthony J AJ

Publication Date: 2022-03

Variant appearance in text: RET: T315I

PubMed Link: 35146190

Variant Present in the following documents:

• Main text
• main.pdf

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FDA-Approved Drugs for Hematological Malignancies-The Last Decade Review.

Cancers

Sochacka-Ćwikła, Aleksandra A; Mączyński, Marcin M; Regiec, Andrzej A

Publication Date: 2021-12-24

Variant appearance in text: RET: T315I

PubMed Link: 35008250

Variant Present in the following documents:

• Main text

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FDA-Approved Drugs for Hematological Malignancies-The Last Decade Review.

Cancers

Sochacka-Ćwikła, Aleksandra A; Mączyński, Marcin M; Regiec, Andrzej A

Publication Date: 2021-12-24

Variant appearance in text: RET: T315I

PubMed Link: 35008250

Variant Present in the following documents:

• Main text

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Anticancer Drugs Approved by the US Food and Drug Administration From 2009 to 2020 According to Their Mechanism of Action.

Jama Network Open

Olivier, Timothée T; Haslam, Alyson A; Prasad, Vinay V

Publication Date: 2021-12-01

Variant appearance in text: RET: T315I

PubMed Link: 34905002

Variant Present in the following documents:

• jamanetwopen-e2138793-s001.pdf

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Synthetic Heterocyclic Derivatives as Kinase Inhibitors Tested for the Treatment of Neuroblastoma.

Molecules (Basel, Switzerland)

Musumeci, Francesca F; Cianciusi, Annarita A; D'Agostino, Ilaria I; Grossi, Giancarlo G; Carbone, Anna A; Schenone, Silvia S

Publication Date: 2021-11-23

Variant appearance in text: RET: T315I

PubMed Link: 34885651

Variant Present in the following documents:

• Main text

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Synthetic Heterocyclic Derivatives as Kinase Inhibitors Tested for the Treatment of Neuroblastoma.

Molecules (Basel, Switzerland)

Musumeci, Francesca F; Cianciusi, Annarita A; D'Agostino, Ilaria I; Grossi, Giancarlo G; Carbone, Anna A; Schenone, Silvia S

Publication Date: 2021-11-23

Variant appearance in text: RET: T315I

PubMed Link: 34885651

Variant Present in the following documents:

• Main text

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Mapping the serum proteome to neurological diseases using whole genome sequencing.

Nature Communications

Png, Grace G; Barysenka, Andrei A; Repetto, Linda L; Navarro, Pau P; Shen, Xia X; Pietzner, Maik M; Wheeler, Eleanor E; Wareham, Nicholas J NJ; Langenberg, Claudia C; Tsafantakis, Emmanouil E; Karaleftheri, Maria M; Dedoussis, George G; Mälarstig, Anders A; Wilson, James F JF; Gilly, Arthur A; Zeggini, Eleftheria E

Publication Date: 2021-12-02

Variant appearance in text: RET: T315I

PubMed Link: 34857772

Variant Present in the following documents:

• 41467_2021_27387_MOESM10_ESM.xlsx, sheet 1

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Mapping the serum proteome to neurological diseases using whole genome sequencing.

Nature Communications

Png, Grace G; Barysenka, Andrei A; Repetto, Linda L; Navarro, Pau P; Shen, Xia X; Pietzner, Maik M; Wheeler, Eleanor E; Wareham, Nicholas J NJ; Langenberg, Claudia C; Tsafantakis, Emmanouil E; Karaleftheri, Maria M; Dedoussis, George G; Mälarstig, Anders A; Wilson, James F JF; Gilly, Arthur A; Zeggini, Eleftheria E

Publication Date: 2021-12-02

Variant appearance in text: RET: T315I

PubMed Link: 34857772

Variant Present in the following documents:

• 41467_2021_27387_MOESM10_ESM.xlsx, sheet 1

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Targeted Therapies in Cancer: To Be or Not to Be, Selective.

Biomedicines

Montoya, Skye S; Soong, Deborah D; Nguyen, Nina N; Affer, Maurizio M; Munamarty, Sailasya P SP; Taylor, Justin J

Publication Date: 2021-11-01

Variant appearance in text: RET: T315I

PubMed Link: 34829820

Variant Present in the following documents:

• biomedicines-09-01591.pdf

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Pyrrolo[2,1-f][1,2,4]triazine: a promising fused heterocycle to target kinases in cancer therapy.

Medicinal Chemistry Research : An International Journal For Rapid Communications On Design And Mechanisms Of Action Of Biologically Active Agents

Singh, Sarbjit S; Utreja, Divya D; Kumar, Vimal V

Publication Date: 2022

Variant appearance in text: RET: T315I

PubMed Link: 34803342

Variant Present in the following documents:

• Main text

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Pyrrolo[2,1-f][1,2,4]triazine: a promising fused heterocycle to target kinases in cancer therapy.

Medicinal Chemistry Research : An International Journal For Rapid Communications On Design And Mechanisms Of Action Of Biologically Active Agents

Singh, Sarbjit S; Utreja, Divya D; Kumar, Vimal V

Publication Date: 2021-11-13

Variant appearance in text: RET: T315I

PubMed Link: 34803342

Variant Present in the following documents:

• Main text

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Innovations and Patent Trends in the Development of USFDA Approved Protein Kinase Inhibitors in the Last Two Decades.

Pharmaceuticals (Basel, Switzerland)

Imran, Mohd M; Asdaq, Syed Mohammed Basheeruddin SMB; Khan, Shah Alam SA; Unnikrishnan Meenakshi, Dhanalekshmi D; Alamri, Abdulhakeem S AS; Alsanie, Walaa F WF; Alhomrani, Majid M; Mohzari, Yahya Y; Alrashed, Ahmed A; AlMotairi, Mohammed M; Alkhaldi, Eman H EH; Alorabi, Abeer K AK; Alshrari, Ahmed Subeh AS; Tauseef, Mohammad M; Abida, ; Alaqel, Saleh I SI; Alam, Ozair O; Bakht, Md Afroz MA

Publication Date: 2021-07-22

Variant appearance in text: RET: T315I

PubMed Link: 34451807

Variant Present in the following documents:

• Main text
• pharmaceuticals-14-00710.pdf

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Phosphorylated WNK kinase networks in recoded bacteria recapitulate physiological function.

Cell Reports

Schiapparelli, Paula P; Pirman, Natasha L NL; Mohler, Kyle K; Miranda-Herrera, Pierre A PA; Zarco, Natanael N; Kilic, Onur O; Miller, Chad C; Shah, Sagar R SR; Rogulina, Svetlana S; Hungerford, William W; Abriola, Laura L; Hoyer, Denton D; Turk, Benjamin E BE; Guerrero-Cázares, Hugo H; Isaacs, Farren J FJ; Quiñones-Hinojosa, Alfredo A; Levchenko, Andre A; Rinehart, Jesse J

Publication Date: 2021-07-20

Variant appearance in text: RET: T315I

PubMed Link: 34289367

Variant Present in the following documents:

• NIHMS1726840-supplement-2.xlsx, sheet 1

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Kinomic profile in patient-derived glioma cells during hypoxia reveals c-MET-PI3K dependency for adaptation.

Theranostics

Cheng, Hong Sheng HS; Marvalim, Charlie C; Zhu, Pengcheng P; Law, Cheng Lui Daniel CLD; Low, Zhi Yan Jeremy ZYJ; Chong, Yuk Kien YK; Ang, Beng Ti BT; Tang, Carol C; Tan, Nguan Soon NS

Publication Date: 2021

Variant appearance in text: RET: T315I

PubMed Link: 33859738

Variant Present in the following documents:

• thnov11p5127s2.xlsx, sheet 1

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Molecules and Mechanisms to Overcome Oxidative Stress Inducing Cardiovascular Disease in Cancer Patients.

Life (Basel, Switzerland)

Sabbatino, Francesco F; Conti, Valeria V; Liguori, Luigi L; Polcaro, Giovanna G; Corbi, Graziamaria G; Manzo, Valentina V; Tortora, Vincenzo V; Carlomagno, Chiara C; Vecchione, Carmine C; Filippelli, Amelia A; Pepe, Stefano S

Publication Date: 2021-01-30

Variant appearance in text: RET: T315I

PubMed Link: 33573162

Variant Present in the following documents:

• Main text
• life-11-00105.pdf

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Recent developments in anticancer kinase inhibitors based on the pyrazolo[3,4-d]pyrimidine scaffold.

Rsc Medicinal Chemistry

Baillache, Daniel J DJ; Unciti-Broceta, Asier A

Publication Date: 2020-10-01

Variant appearance in text: RET: T315I

PubMed Link: 33479617

Variant Present in the following documents:

• Main text
• MD-011-D0MD00227E.pdf

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Cardiotoxicity of Novel Targeted Hematological Therapies.

Life (Basel, Switzerland)

Giudice, Valentina V; Vecchione, Carmine C; Selleri, Carmine C

Publication Date: 2020-12-11

Variant appearance in text: RET: T315I

PubMed Link: 33322351

Variant Present in the following documents:

• Main text

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Fibroblast growth factor receptors in cancer: genetic alterations, diagnostics, therapeutic targets and mechanisms of resistance.

British Journal Of Cancer

Krook, Melanie A MA; Reeser, Julie W JW; Ernst, Gabrielle G; Barker, Hannah H; Wilberding, Max M; Li, Gary G; Chen, Hui-Zi HZ; Roychowdhury, Sameek S

Publication Date: 2021-03

Variant appearance in text: RET: T315I

PubMed Link: 33268819

Variant Present in the following documents:

• Main text
• 41416_2020_Article_1157.pdf

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KF-1607, a Novel Pan Src Kinase Inhibitor, Attenuates Obstruction-Induced Tubulointerstitial Fibrosis in Mice.

Biomolecules & Therapeutics

Dorotea, Debra D; Lee, Seungyeon S; Lee, Sun Joo SJ; Lee, Gayoung G; Son, Jung Beom JB; Choi, Hwan Geun HG; Ahn, Sung-Min SM; Ha, Hunjoo H

Publication Date: 2021-01-01

Variant appearance in text: RET: T315I

PubMed Link: 32690822

Variant Present in the following documents:

• bt-29-1-41.pdf

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Nanotechnology for angiogenesis: opportunities and challenges.

Chemical Society Reviews

Kargozar, Saeid S; Baino, Francesco F; Hamzehlou, Sepideh S; Hamblin, Michael R MR; Mozafari, Masoud M

Publication Date: 2020-07-21

Variant appearance in text: RET: T315I

PubMed Link: 32538379

Variant Present in the following documents:

• Main text

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Toward a More Precise Future for Oncology.

Cancer Cell

Murciano-Goroff, Yonina R YR; Taylor, Barry S BS; Hyman, David M DM; Schram, Alison M AM

Publication Date: 2020-04-13

Variant appearance in text: RET: T315I

PubMed Link: 32289268

Variant Present in the following documents:

• Main text

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Tyrosine Kinase Inhibitors in Cancer: Breakthrough and Challenges of Targeted Therapy.

Cancers

Pottier, Charles C; Fresnais, Margaux M; Gilon, Marie M; Jérusalem, Guy G; Longuespée, Rémi R; Sounni, Nor Eddine NE

Publication Date: 2020-03-20

Variant appearance in text: RET: T315I

PubMed Link: 32244867

Variant Present in the following documents:

• Main text
• cancers-12-00731.pdf

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Advances in Targeting RET-Dependent Cancers.

Cancer Discovery

Subbiah, Vivek V; Cote, Gilbert J GJ

Publication Date: 2020-04

Variant appearance in text: RET: T315I

PubMed Link: 32094155

Variant Present in the following documents:

• Main text

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HDAC6-an Emerging Target Against Chronic Myeloid Leukemia?

Cancers

Losson, Hélène H; Schnekenburger, Michael M; Dicato, Mario M; Diederich, Marc M

Publication Date: 2020-01-29

Variant appearance in text: RET: T315I

PubMed Link: 32013157

Variant Present in the following documents:

• Main text
• cancers-12-00318.pdf

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Reimbursement Status and Recommendations Related to Orphan Drugs in European Countries.

Frontiers In Pharmacology

Stawowczyk, Ewa E; Malinowski, Krzysztof Piotr KP; Kawalec, Paweł P; Bobiński, Rafał R; Siwiec, Jacek J; Panteli, Dimitra D; Eckhardt, Helene H; Simoens, Steven S; Agusti, Antònia A; Dooms, Marc M; Pilc, Andrzej A

Publication Date: 2019

Variant appearance in text: RET: T315I

PubMed Link: 31827433

Variant Present in the following documents:

• Table_2.pdf

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BCR: a promiscuous fusion partner in hematopoietic disorders.

Oncotarget

Peiris, Malalage N MN; Li, Fangda F; Donoghue, Daniel J DJ

Publication Date: 2019-04-12

Variant appearance in text: RET: T315I

PubMed Link: 31105873

Variant Present in the following documents:

• Main text

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Repurposing Ponatinib as a Potent Agent against KIT Mutant Melanomas.

Theranostics

Han, Yong Y; Gu, Ziyue Z; Wu, Jing J; Huang, Xiaojuan X; Zhou, Rong R; Shi, Chaoji C; Tao, Wenjie W; Wang, Lizhen L; Wang, Yanan Y; Zhou, Guoyu G; Li, Jiang J; Zhang, Zhiyuan Z; Sun, Shuyang S

Publication Date: 2019

Variant appearance in text: RET: T315I

PubMed Link: 31037149

Variant Present in the following documents:

• Main text
• thnov09p1952.pdf

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Computational algorithms for in silico profiling of activating mutations in cancer.

Cellular And Molecular Life Sciences : Cmls

Jordan, E Joseph EJ; Patil, Keshav K; Suresh, Krishna K; Park, Jin H JH; Mosse, Yael P YP; Lemmon, Mark A MA; Radhakrishnan, Ravi R

Publication Date: 2019-07

Variant appearance in text: RET: T315I

PubMed Link: 30982079

Variant Present in the following documents:

• Main text

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Therapeutic Modulation of Autophagy in Leukaemia and Lymphoma.

Cells

Djavaheri-Mergny, Mojgan M; Giuriato, Sylvie S; Tschan, Mario P MP; Humbert, Magali M

Publication Date: 2019-01-30

Variant appearance in text: RET: T315I

PubMed Link: 30704144

Variant Present in the following documents:

• Main text

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Recent Studies on Ponatinib in Cancers Other Than Chronic Myeloid Leukemia.

Cancers

Musumeci, Francesca F; Greco, Chiara C; Grossi, Giancarlo G; Molinari, Alessio A; Schenone, Silvia S

Publication Date: 2018-11-09

Variant appearance in text: RET: T315I

PubMed Link: 30423915

Variant Present in the following documents:

• Main text
• cancers-10-00430.pdf

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RET fusions observed in lung and colorectal cancers are sensitive to ponatinib.

Oncotarget

Gozgit, Joseph M JM; Chen, Tzu-Hsiu TH; Song, Youngchul Y; Wardwell, Scott S; Wang, Frank F; Cai, Jie J; Li, Henry H; Edgren, Henrik H; Rivera, Victor M VM; Pritchard, Justin J

Publication Date: 2018-07-03

Variant appearance in text: RET: T315I

PubMed Link: 30038711

Variant Present in the following documents:

• Main text
• oncotarget-09-29654.pdf

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Inhibition of mTORC1/C2 signaling improves anti-leukemia efficacy of JAK/STAT blockade in CRLF2 rearranged and/or JAK driven Philadelphia chromosome-like acute B-cell lymphoblastic leukemia.

Oncotarget

Zhang, Qi Q; Shi, Ce C; Han, Lina L; Jain, Nitin N; Roberts, Kathryn G KG; Ma, Helen H; Cai, Tianyu T; Cavazos, Antonio A; Tabe, Yoko Y; Jacamo, Rodrigo O RO; Mu, Hong H; Zhao, Yang Y; Wang, Jing J; Wu, Shuo-Chieh SC; Cao, Fenglin F; Zeng, Zhihong Z; Zhou, Jin J; Mi, Yingchang Y; Jabbour, Elias J EJ; Levine, Ross R; Tasian, Sarah K SK; Mullighan, Charles G CG; Weinstock, David M DM; Fruman, David A DA; Konopleva, Marina M

Publication Date: 2018-01-30

Variant appearance in text: RET: T315I

PubMed Link: 29487712

Variant Present in the following documents:

• Main text

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Precision Oncology Decision Support: Current Approaches and Strategies for the Future.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Kurnit, Katherine C KC; Dumbrava, Ecaterina E Ileana EEI; Litzenburger, Beate B; Khotskaya, Yekaterina B YB; Johnson, Amber M AM; Yap, Timothy A TA; Rodon, Jordi J; Zeng, Jia J; Shufean, Md Abu MA; Bailey, Ann M AM; Sánchez, Nora S NS; Holla, Vijaykumar V; Mendelsohn, John J; Shaw, Kenna Mills KM; Bernstam, Elmer V EV; Mills, Gordon B GB; Meric-Bernstam, Funda F

Publication Date: 2018-06-15

Variant appearance in text: RET: T315I

PubMed Link: 29420224

Variant Present in the following documents:

• Main text

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Recent advances in the biology and therapy of medullary thyroid carcinoma.

F1000Research

Nelkin, Barry B

Publication Date: 2017

Variant appearance in text: RET: T315I

PubMed Link: 29333262

Variant Present in the following documents:

• Main text
• f1000research-6-13691.pdf

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Data driven polypharmacological drug design for lung cancer: analyses for targeting ALK, MET, and EGFR.

Journal Of Cheminformatics

Narayanan, Dilip D; Gani, Osman A B S M OABSM; Gruber, Franz X E FXE; Engh, Richard A RA

Publication Date: 2017-07-04

Variant appearance in text: RET: T315I

PubMed Link: 29086093

Variant Present in the following documents:

• 13321_2017_Article_229.pdf

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The molecular basis for RET tyrosine-kinase inhibitors in thyroid cancer.

Best Practice & Research. Clinical Endocrinology & Metabolism

De Falco, Valentina V; Carlomagno, Francesca F; Li, Hong-Yu HY; Santoro, Massimo M

Publication Date: 2017-06

Variant appearance in text: RET: T315I

PubMed Link: 28911727

Variant Present in the following documents:

• Main text

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Osimertinib in the treatment of non-small-cell lung cancer: design, development and place in therapy.

Lung Cancer (Auckland, N.Z.)

Santarpia, Mariacarmela M; Liguori, Alessia A; Karachaliou, Niki N; Gonzalez-Cao, Maria M; Daffinà, Maria Grazia MG; D'Aveni, Alessandro A; Marabello, Grazia G; Altavilla, Giuseppe G; Rosell, Rafael R

Publication Date: 2017

Variant appearance in text: RET: T315I

PubMed Link: 28860885

Variant Present in the following documents:

• Main text

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Biomarker-Defined Subsets of Common Diseases: Policy and Economic Implications of Orphan Drug Act Coverage.

Plos Medicine

Kesselheim, Aaron S AS; Treasure, Carolyn L CL; Joffe, Steven S

Publication Date: 2017-01

Variant appearance in text: RET: T315I

PubMed Link: 28045970

Variant Present in the following documents:

• Main text
• pmed.1002190.pdf

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Resisting Resistance: Targeted Therapies in Lung Cancer.

Trends In Cancer

Lin, Jessica J JJ; Shaw, Alice T AT

Publication Date: 2016-07

Variant appearance in text: RET: T315I

PubMed Link: 27819059

Variant Present in the following documents:

• Main text

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Polypharmacology in Precision Oncology: Current Applications and Future Prospects.

Current Pharmaceutical Design

Antolin, Albert A AA; Workman, Paul P; Mestres, Jordi J; Al-Lazikani, Bissan B

Publication Date: 2016

Variant appearance in text: RET: T315I

PubMed Link: 27669965

Variant Present in the following documents:

• Main text

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Novel multiple tyrosine kinase inhibitor ponatinib inhibits bFGF-activated signaling in neuroblastoma cells and suppresses neuroblastoma growth in vivo.

Oncotarget

Li, Haoyu H; Wang, Yongfeng Y; Chen, Zhenghu Z; Lu, Jiaxiong J; Pan, Jessie J; Yu, Yang Y; Zhao, Yanling Y; Zhang, Huiyuan H; Hu, Ting T; Liu, Qing Q; Yang, Jianhua J

Publication Date: 2017-01-24

Variant appearance in text: RET: T315I

PubMed Link: 27564113

Variant Present in the following documents:

• oncotarget-08-5874.pdf

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Oncogenic kinase fusions: an evolving arena with innovative clinical opportunities.

Oncotarget

Tabbò, Fabrizio F; Pizzi, Marco M; Kyriakides, Peter W PW; Ruggeri, Bruce B; Inghirami, Giorgio G

Publication Date: 2016-05-03

Variant appearance in text: RET: T315I

PubMed Link: 26943776

Variant Present in the following documents:

• Main text

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Kinase Inhibitor Profiling Reveals Unexpected Opportunities to Inhibit Disease-Associated Mutant Kinases.

Cell Reports

Duong-Ly, Krisna C KC; Devarajan, Karthik K; Liang, Shuguang S; Horiuchi, Kurumi Y KY; Wang, Yuren Y; Ma, Haiching H; Peterson, Jeffrey R JR

Publication Date: 2016-02-02

Variant appearance in text: RET: T315I

PubMed Link: 26776524

Variant Present in the following documents:

• Main text

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Aurora Kinase Inhibitors: Current Status and Outlook.

Frontiers In Oncology

Bavetsias, Vassilios V; Linardopoulos, Spiros S

Publication Date: 2015

Variant appearance in text: RET: T315I

PubMed Link: 26734566

Variant Present in the following documents:

• Main text
• fonc-05-00278.pdf

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Recent Advances in the Development of Antineoplastic Agents Derived from Natural Products.

Drugs

Trendowski, Matthew M

Publication Date: 2015-11

Variant appearance in text: RET: T315I

PubMed Link: 26501980

Variant Present in the following documents:

• Main text

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Activity of the Type II JAK2 Inhibitor CHZ868 in B Cell Acute Lymphoblastic Leukemia.

Cancer Cell

Wu, Shuo-Chieh SC; Li, Loretta S LS; Kopp, Nadja N; Montero, Joan J; Chapuy, Bjoern B; Yoda, Akinori A; Christie, Amanda L AL; Liu, Huiyun H; Christodoulou, Alexandra A; van Bodegom, Diederik D; van der Zwet, Jordy J; Layer, Jacob V JV; Tivey, Trevor T; Lane, Andrew A AA; Ryan, Jeremy A JA; Ng, Samuel Y SY; DeAngelo, Daniel J DJ; Stone, Richard M RM; Steensma, David D; Wadleigh, Martha M; Harris, Marian M; Mandon, Emeline E; Ebel, Nicolas N; Andraos, Rita R; Romanet, Vincent V; Dölemeyer, Arno A; Sterker, Dario D; Zender, Michael M; Rodig, Scott J SJ; Murakami, Masato M; Hofmann, Francesco F; Kuo, Frank F; Eck, Michael J MJ; Silverman, Lewis B LB; Sallan, Stephen E SE; Letai, Anthony A; Baffert, Fabienne F; Vangrevelinghe, Eric E; Radimerski, Thomas T; Gaul, Christoph C; Weinstock, David M DM

Publication Date: 2015-07-13

Variant appearance in text: RET: T315I

PubMed Link: 26175414

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Anchor-based classification and type-C inhibitors for tyrosine kinases.

Scientific Reports

Hsu, Kai-Cheng KC; Sung, Tzu-Ying TY; Lin, Chih-Ta CT; Chiu, Yi-Yuan YY; Hsu, John T-A JT; Hung, Hui-Chen HC; Sun, Chung-Ming CM; Barve, Indrajeet I; Chen, Wen-Liang WL; Huang, Wen-Chien WC; Huang, Chin-Ting CT; Chen, Chun-Hwa CH; Yang, Jinn-Moon JM

Publication Date: 2015-06-16

Variant appearance in text: RET: T315I

PubMed Link: 26077136

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The study of homology between tumor progression genes and members of retroviridae as a tool to predict target-directed therapy failure.

Frontiers In Pharmacology

Fernandes, Janaina J

Publication Date: 2015

Variant appearance in text: RET: T315I

PubMed Link: 25983693

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