RET c.1901G>A ;(p.C634Y)

Variant ID: 10-43609949-G-A

NM_020975.4(RET):c.1901G>A;(p.C634Y)

This variant was identified in 166 publications

View GRCh38 version.




Publications:


Primary Hyperparathyroidism in Multiple Endocrine Neoplasia Type 2A in Denmark: A Nationwide Population-Based Retrospective Study in Denmark 1930-2021.

Cancers
Holm, Magnus M; Vestergaard, Peter P; Poulsen, Morten Møller MM; Rasmussen, Åse Krogh ÅK; Feldt-Rasmussen, Ulla U; Bay, Mette M; Rolighed, Lars L; Londero, Stefano S; Pedersen, Henrik Baymler HB; Hahn, Christoffer Holst CH; Rask, Klara Bay KB; Nielsen, Heidi Hvid HH; Gaustadnes, Mette M; Rossing, Maria Caroline MC; Hermann, Anne Pernille AP; Godballe, Christian C; Mathiesen, Jes Sloth JS
Publication Date: 2023-04-02

Variant appearance in text: RET: Cys634Tyr
PubMed Link: 37046785
Variant Present in the following documents:
  • Main text
  • cancers-15-02125.pdf
View BVdb publication page



Novel and recurrent genetic variants of VHL, SDHB, and RET genes in Chinese pheochromocytoma and paraganglioma patients.

Frontiers In Genetics
Li, Chong C; Li, Jingyi J; Han, Chao C; Wang, Ting T; Zhang, Lixia L; Wang, Zhifang Z; Wang, Tingting T; Xu, Lijun L; Qi, Guangzhao G; Qin, Guijun G; Li, Xialian X; Zheng, Lili L
Publication Date: 2023

Variant appearance in text: RET: 1901G>A; C634Y; rs75996173
PubMed Link: 36936415
Variant Present in the following documents:
  • Main text
  • fgene-14-959989.pdf
View BVdb publication page



Recapitulating thyroid cancer histotypes through engineering embryonic stem cells.

Nature Communications
Veschi, Veronica V; Turdo, Alice A; Modica, Chiara C; Verona, Francesco F; Di Franco, Simone S; Gaggianesi, Miriam M; Tirrò, Elena E; Di Bella, Sebastiano S; Iacono, Melania Lo ML; Pantina, Vincenzo Davide VD; Porcelli, Gaetana G; Mangiapane, Laura Rosa LR; Bianca, Paola P; Rizzo, Aroldo A; Sciacca, Elisabetta E; Pillitteri, Irene I; Vella, Veronica V; Belfiore, Antonino A; Bongiorno, Maria Rita MR; Pistone, Giuseppe G; Memeo, Lorenzo L; Colarossi, Lorenzo L; Giuffrida, Dario D; Colarossi, Cristina C; Vigneri, Paolo P; Todaro, Matilde M; Stassi, Giorgio G
Publication Date: 2023-03-11

Variant appearance in text: RET: 1901G>A; Cys634Tyr
PubMed Link: 36906579
Variant Present in the following documents:
  • 41467_2023_36922_MOESM5_ESM.xlsx, sheet 1
View BVdb publication page



Simultaneous bilateral laparoscopic cortical-sparing adrenalectomy for bilateral pheochromocytomas in multiple endocrine neoplasia type 2.

Frontiers In Surgery
Qi, Xiao-Ping XP; Lian, Bi-Jun BJ; Fang, Xu-Dong XD; Dong, Fang F; Li, Feng F; Jin, Hang-Yang HY; Zhang, Ke K; Wang, Kang-Er KE; Zhang, Yi Y
Publication Date: 2022

Variant appearance in text: RET: C634Y
PubMed Link: 36704524
Variant Present in the following documents:
  • Main text
  • fsurg-09-1057821.pdf
View BVdb publication page



Integrated proteogenomic characterization of medullary thyroid carcinoma.

Cell Discovery
Shi, Xiao X; Sun, Yaoting Y; Shen, Cenkai C; Zhang, Yan Y; Shi, Rongliang R; Zhang, Fan F; Liao, Tian T; Lv, Guojun G; Zhu, Zhengcai Z; Jiao, Lianghe L; Li, Peng P; Xu, Tiansheng T; Qu, Ning N; Huang, Naisi N; Hu, Jiaqian J; Zhang, Tingting T; Gu, Yanzi Y; Qin, Guangqi G; Guan, Haixia H; Pu, Weilin W; Li, Yuan Y; Geng, Xiang X; Zhang, Yan Y; Chen, Tongzhen T; Huang, Shenglin S; Zhang, Zhikang Z; Ge, Shuting S; Wang, Wu W; Xu, Weibo W; Yu, Pengcheng P; Lu, Zhongwu Z; Wang, Yulong Y; Guo, Liang L; Wang, Yu Y; Guo, Tiannan T; Ji, Qinghai Q; Wei, Wenjun W
Publication Date: 2022-11-08

Variant appearance in text: RET: C634Y; rs75996173
PubMed Link: 36344509
Variant Present in the following documents:
  • 41421_2022_479_MOESM4_ESM.xlsx, sheet 2
  • 41421_2022_479_MOESM4_ESM.xlsx, sheet 3
  • 41421_2022_479_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Single-nuclei and bulk-tissue gene-expression analysis of pheochromocytoma and paraganglioma links disease subtypes with tumor microenvironment.

Nature Communications
Zethoven, Magnus M; Martelotto, Luciano L; Pattison, Andrew A; Bowen, Blake B; Balachander, Shiva S; Flynn, Aidan A; Rossello, Fernando J FJ; Hogg, Annette A; Miller, Julie A JA; Frysak, Zdenek Z; Grimmond, Sean S; Fishbein, Lauren L; Tischler, Arthur S AS; Gill, Anthony J AJ; Hicks, Rodney J RJ; Dahia, Patricia L M PLM; Clifton-Bligh, Roderick R; Pacak, Karel K; Tothill, Richard W RW
Publication Date: 2022-10-21

Variant appearance in text: RET: Cys634Tyr
PubMed Link: 36271074
Variant Present in the following documents:
  • 41467_2022_34011_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Mutational Profile and Potential Molecular Therapeutic Targets of Pheochromocytoma.

Frontiers In Endocrinology
Ma, Xiaosen X; Ling, Chao C; Zhao, Meng M; Wang, Fen F; Cui, Yunying Y; Wen, Jin J; Ji, Zhigang Z; Zhang, Caili C; Chen, Shi S; Tong, Anli A; Li, Yuxiu Y
Publication Date: 2022

Variant appearance in text: RET: C634Y
PubMed Link: 35966080
Variant Present in the following documents:
  • Table_1.xlsx, sheet 5
View BVdb publication page



Medullary Thyroid Carcinoma and Associated Endocrinopathies in Slovenia from 1995 to 2021.

Life (Basel, Switzerland)
Milicevic, Sara S; Krajc, Mateja M; Blatnik, Ana A; Peric, Barbara B
Publication Date: 2022-07-21

Variant appearance in text: RET: C634Y
PubMed Link: 35888179
Variant Present in the following documents:
  • Main text
  • life-12-01091.pdf
View BVdb publication page



Comprehensive Assessment of Indian Variations in the Druggable Kinome Landscape Highlights Distinct Insights at the Sequence, Structure and Pharmacogenomic Stratum.

Frontiers In Pharmacology
Panda, Gayatri G; Mishra, Neha N; Sharma, Disha D; Kutum, Rintu R; Bhoyar, Rahul C RC; Jain, Abhinav A; Imran, Mohamed M; Senthilvel, Vigneshwar V; Divakar, Mohit Kumar MK; Mishra, Anushree A; Garg, Parth P; Banerjee, Priyanka P; Sivasubbu, Sridhar S; Scaria, Vinod V; Ray, Arjun A
Publication Date: 2022

Variant appearance in text: RET: C634Y; rs75996173
PubMed Link: 35865963
Variant Present in the following documents:
  • Table12.xlsx, sheet 1
View BVdb publication page



Recent progress on vascular endothelial growth factor receptor inhibitors with dual targeting capabilities for tumor therapy.

Journal Of Hematology & Oncology
Liu, Yun Y; Li, Yang Y; Wang, Yuxi Y; Lin, Congcong C; Zhang, Dan D; Chen, Juncheng J; Ouyang, Liang L; Wu, Fengbo F; Zhang, Jifa J; Chen, Lei L
Publication Date: 2022-07-07

Variant appearance in text: RET: C634Y
PubMed Link: 35799213
Variant Present in the following documents:
  • Main text
View BVdb publication page



Medullary Thyroid Carcinoma Mutational Spectrum Update and Signaling-Type Inference by Transcriptional Profiles: Literature Meta-Analysis and Study of Tumor Samples.

Cancers
Minna, Emanuela E; Romeo, Paola P; Dugo, Matteo M; De Cecco, Loris L; Aiello, Antonella A; Pistore, Federico F; Carenzo, Andrea A; Greco, Angela A; Borrello, Maria Grazia MG
Publication Date: 2022-04-13

Variant appearance in text: RET: C634Y
PubMed Link: 35454858
Variant Present in the following documents:
  • Main text
  • cancers-14-01951.pdf
View BVdb publication page



Multiple endocrine neoplasia 2: an overview.

Therapeutic Advances In Chronic Disease
Saravana-Bawan, B B; Pasternak, J D JD
Publication Date: 2022

Variant appearance in text: MEN2A: Cys634Tyr
PubMed Link: 35237400
Variant Present in the following documents:
  • Main text
  • 10.1177_20406223221079246.pdf
View BVdb publication page



Germline RET Leu56Met Variant Is Likely Not Causative of Multiple Endocrine Neoplasia Type 2.

Frontiers In Endocrinology
Hansen, Anna Reimer AR; Borgwardt, Line L; Rasmussen, Åse Krogh ÅK; Godballe, Christian C; Poulsen, Morten Møller MM; Vieira, Filipe G FG; Mathiesen, Jes Sloth JS; Rossing, Maria M
Publication Date: 2021

Variant appearance in text: RET: Cys634Tyr
PubMed Link: 34925234
Variant Present in the following documents:
  • Main text
  • fendo-12-764512.pdf
View BVdb publication page



RET Proto-Oncogene Mutational Analysis in 45 Iranian Patients Affected with Medullary Thyroid Carcinoma: Report of a New Variant.

Journal Of Thyroid Research
Damavandi, Elia E; Vand-Rajabpour, Fatemeh F; Javadi-Arjmand, Maliheh M; Mohajeri Tehrani, Mohammad-Reza MR; Larijani, Bagher B; Kabuli, Majid M; Ghadami, Mohsen M
Publication Date: 2021

Variant appearance in text: RET: 1901G>A
PubMed Link: 34777782
Variant Present in the following documents:
  • JTR2021-7250870.pdf
View BVdb publication page



Active Surveillance in RET Gene Carriers Belonging to Families with Multiple Endocrine Neoplasia.

Cancers
Prete, Alessandro A; Matrone, Antonio A; Gambale, Carla C; Bottici, Valeria V; Cappagli, Virginia V; Romei, Cristina C; Torregrossa, Liborio L; Valerio, Laura L; Minaldi, Elisa E; Campopiano, Maria Cristina MC; Lorusso, Loredana L; Agate, Laura L; Molinaro, Eleonora E; Viola, David D; Ramone, Teresa T; Mulè, Chiara C; Ciampi, Raffaele R; Basolo, Fulvio F; Elisei, Rossella R
Publication Date: 2021-11-05

Variant appearance in text: RET: C634Y
PubMed Link: 34771717
Variant Present in the following documents:
  • Main text
View BVdb publication page



Parathyroid Tumors: Molecular Signatures.

International Journal Of Molecular Sciences
Marini, Francesca F; Giusti, Francesca F; Iantomasi, Teresa T; Brandi, Maria Luisa ML
Publication Date: 2021-10-18

Variant appearance in text: MEN2A: Cys634Tyr
PubMed Link: 34681865
Variant Present in the following documents:
  • Main text
View BVdb publication page



Metastatic cluster 2-related pheochromocytoma/paraganglioma: a single-center experience and systematic review.

Endocrine Connections
Kumar, Sandeep S; Lila, Anurag Ranjan AR; Memon, Saba Samad SS; Sarathi, Vijaya V; Patil, Virendra A VA; Menon, Santosh S; Mittal, Neha N; Prakash, Gagan G; Malhotra, Gaurav G; Shah, Nalini S NS; Bandgar, Tushar R TR
Publication Date: 2021-11-11

Variant appearance in text: MEN2A: 1901G>A
PubMed Link: 34662294
Variant Present in the following documents:
  • Main text
  • EC-21-0455.pdf
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: RET: C634Y
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Late-Onset Medullary Thyroid Cancer in a Patient with a Germline RET Codon C634R Mutation.

Diagnostics (Basel, Switzerland)
Walczyk, Agnieszka A; Zgubieński, Kajetan K; Chmielewski, Grzegorz G; Hińcza-Nowak, Kinga K; Kowalik, Artur A; Jaskulski, Jarosław J; Kowalska, Aldona A
Publication Date: 2021-08-11

Variant appearance in text: RET: C634Y
PubMed Link: 34441382
Variant Present in the following documents:
  • Main text
View BVdb publication page



Prevalence of Germline Variants in a Large Cohort of Japanese Patients with Pheochromocytoma and/or Paraganglioma.

Cancers
Yonamine, Masato M; Wasano, Koichiro K; Aita, Yuichi Y; Sugasawa, Takehito T; Takahashi, Katsutoshi K; Kawakami, Yasushi Y; Shimano, Hitoshi H; Nishiyama, Hiroyuki H; Hara, Hisato H; Naruse, Mitsuhide M; Okamoto, Takahiro T; Matsuda, Tadashi T; Kosugi, Shinji S; Horiguchi, Kazuhiko K; Tanabe, Akiyo A; Watanabe, Atsushi A; Kimura, Noriko N; Nakamura, Eijiro E; Sakurai, Akihiro A; Shiga, Kiyoto K; Takekoshi, Kazuhiro K
Publication Date: 2021-08-09

Variant appearance in text: RET: 1901G>A; C634Y
PubMed Link: 34439168
Variant Present in the following documents:
  • Main text
View BVdb publication page



Targeted activity of the small molecule kinase inhibitor Pz-1 towards RET and TRK kinases.

Scientific Reports
Moccia, Marialuisa M; Yang, Donglin D; Lakkaniga, Naga Rajiv NR; Frett, Brendan B; McConnell, Nicholas N; Zhang, Lingtian L; Brescia, Annalisa A; Federico, Giorgia G; Zhang, Lingzhi L; Salerno, Paolo P; Santoro, Massimo M; Li, Hong-Yu HY; Carlomagno, Francesca F
Publication Date: 2021-08-09

Variant appearance in text: RET: C634Y
PubMed Link: 34373541
Variant Present in the following documents:
  • Main text
  • 41598_2021_Article_95612.pdf
View BVdb publication page



Surgical Remission of Diabetes in a Patient With Mutation of RET Proto-Oncogene.

Aace Clinical Case Reports
Concepción Zavaleta, Marcio José MJ; Armas Flórez, Cristian David CD; Benites Moya, Cesar Joel CJ; Plasencia Dueñas, Esteban Alberto EA; Ildefonso Najarro, Sofia Pilar SP; Palomino Taype, Kely K; Durand Torres, Ricardo R; Massucco Revoredo, Frederick F
Publication Date: 2021

Variant appearance in text: RET: 1901G>A
PubMed Link: 34307848
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Crude annual incidence rate of medullary thyroid cancer and RET mutation frequency.

Croatian Medical Journal
Milićević, Sara S; Bergant, Damijan D; Žagar, Tina T; Perić, Barbara B
Publication Date: 2021-04-30

Variant appearance in text: RET: C634Y
PubMed Link: 33938650
Variant Present in the following documents:
  • Main text
View BVdb publication page



Medullary thyroid cancer: molecular factors, management and treatment.

Romanian Journal Of Morphology And Embryology = Revue Roumaine De Morphologie Et Embryologie
Pavlidis, Efstathios E; Sapalidis, Konstantinos K; Chatzinikolaou, Fotios F; Kesisoglou, Isaak I
Publication Date: 2020

Variant appearance in text: RET: C634Y
PubMed Link: 33817709
Variant Present in the following documents:
  • Main text
View BVdb publication page



Germline Pathogenic Variants Identified by Targeted Next-Generation Sequencing of Susceptibility Genes in Pheochromocytoma and Paraganglioma.

Journal Of Kidney Cancer And Vhl
Yalcintepe, Sinem S; Gurkan, Hakan H; Korkmaz, Fatma Nur FN; Demir, Selma S; Atli, Engin E; Eker, Damla D; Guler, Hazal Sezginer HS; Zhuri, Drenusha D; Atli, Emine Ikbal EI; Salt, Semra Ayturk SA; Sahin, Mustafa M; Guldiken, Sibel S
Publication Date: 2021

Variant appearance in text: N/A
PubMed Link: 33777662
Variant Present in the following documents:
View BVdb publication page



Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer
Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA
Publication Date: 2021-05

Variant appearance in text: RET: 1901G>A; C634Y
PubMed Link: 33704917
Variant Present in the following documents:
  • TCA-12-1271-s003.xls, sheet 1
View BVdb publication page



Significance of chromogranin A and synaptophysin in medullary thyroid carcinoma.

Bosnian Journal Of Basic Medical Sciences
Tomita, Tatsuo T
Publication Date: 2021-10-01

Variant appearance in text: RET: C634Y
PubMed Link: 33485291
Variant Present in the following documents:
  • BJBMS-24-535.pdf
View BVdb publication page



RMRP, RMST, FTX and IPW: novel potential long non-coding RNAs in medullary thyroid cancer.

Orphanet Journal Of Rare Diseases
Luzón-Toro, Berta B; Villalba-Benito, Leticia L; Fernández, Raquel María RM; Torroglosa, Ana A; Antiñolo, Guillermo G; Borrego, Salud S
Publication Date: 2021-01-06

Variant appearance in text: MEN2A: Cys634Tyr
PubMed Link: 33407723
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic and Clinical Profiles of Pheochromocytoma and Paraganglioma: A Single Center Study.

Frontiers In Endocrinology
Ma, Xiaosen X; Li, Ming M; Tong, Anli A; Wang, Fen F; Cui, Yunying Y; Zhang, Xuebin X; Zhang, Yushi Y; Chen, Shi S; Li, Yuxiu Y
Publication Date: 2020

Variant appearance in text: RET: 1901G>A; C634Y
PubMed Link: 33362715
Variant Present in the following documents:
  • Main text
  • fendo-11-574662.pdf
View BVdb publication page



Results and Clinical Interpretation of Germline RET Analysis in a Series of Patients with Medullary Thyroid Carcinoma: The Challenge of the Variants of Uncertain Significance.

Cancers
Innella, Giovanni G; Rossi, Cesare C; Romagnoli, Maria M; Repaci, Andrea A; Bianchi, Davide D; Cantarini, Maria Elena ME; Martorana, Davide D; Godino, Lea L; Pession, Andrea A; Percesepe, Antonio A; Pagotto, Uberto U; Turchetti, Daniela D
Publication Date: 2020-11-05

Variant appearance in text: MEN2B: 1901G>A
PubMed Link: 33167350
Variant Present in the following documents:
  • Main text
View BVdb publication page



Modeling cancer progression using human pluripotent stem cell-derived cells and organoids.

Stem Cell Research
Zhang, Meili M; Vandana, J Jeya JJ; Lacko, Lauretta L; Chen, Shuibing S
Publication Date: 2020-12

Variant appearance in text: RET: C634Y
PubMed Link: 33137568
Variant Present in the following documents:
  • Main text
View BVdb publication page



Current status of the prognostic molecular markers in medullary thyroid carcinoma.

Endocrine Connections
Oczko-Wojciechowska, Malgorzata M; Czarniecka, Agnieszka A; Gawlik, Tomasz T; Jarzab, Barbara B; Krajewska, Jolanta J
Publication Date: 2020-12

Variant appearance in text: RET: C634Y
PubMed Link: 33112827
Variant Present in the following documents:
  • EC-20-0374.pdf
View BVdb publication page



5P Strategies for Management of Multiple Endocrine Neoplasia Type 2: A Paradigm of Precision Medicine.

Frontiers In Endocrinology
Li, Shu-Yuan SY; Ding, Yi-Qiang YQ; Si, You-Liang YL; Ye, Mu-Jin MJ; Xu, Chen-Ming CM; Qi, Xiao-Ping XP
Publication Date: 2020

Variant appearance in text: RET: C634Y
PubMed Link: 33071967
Variant Present in the following documents:
  • Main text
View BVdb publication page



Usefulness of a novel device to divide core needle biopsy specimens in a spatially matched fashion.

Scientific Reports
Shiraishi, Takumi T; Inui, Shogo S; Inoue, Yuta Y; Saito, Yumiko Y; Taga, Hideto H; Kaneko, Masatomo M; Tsuji, Keisuke K; Ueda, Saya S; Ueda, Takashi T; Matsugasumi, Toru T; Taniguchi, Hidefumi H; Ueno, Akihisa A; Yamada, Takeshi T; Yamada, Yasuhiro Y; Iwata, Tsuyoshi T; Fujihara, Atsuko A; Hongo, Fumiya F; Ukimura, Osamu O
Publication Date: 2020-10-13

Variant appearance in text: rs75996173
PubMed Link: 33051506
Variant Present in the following documents:
  • 41598_2020_74136_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



The synergy of germline C634Y and V292M RET mutations in a northern Chinese family with multiple endocrine neoplasia type 2A.

Journal Of Cellular And Molecular Medicine
Yang, Zheng Z; Qi, Xinmeng X; Gross, Neil N; Kou, Xiujuan X; Bai, Yunlong Y; Feng, Yaru Y; Wang, Bochun B; Zafereo, Mark E ME; Li, Guojun G; Sun, Chuanzheng C; Li, Huihui H; Chen, Xiaohong X; Huang, Zhigang Z
Publication Date: 2020-11

Variant appearance in text: RET: 1901G>A
PubMed Link: 32989896
Variant Present in the following documents:
  • Main text
  • JCMM-24-13163.pdf
View BVdb publication page



Ancestry-specific predisposing germline variants in cancer.

Genome Medicine
Oak, Ninad N; Cherniack, Andrew D AD; Mashl, R Jay RJ; , ; Hirsch, Fred R FR; Ding, Li L; Beroukhim, Rameen R; Gümüş, Zeynep H ZH; Plon, Sharon E SE; Huang, Kuan-Lin KL
Publication Date: 2020-05-29

Variant appearance in text: RET: C634Y
PubMed Link: 32471518
Variant Present in the following documents:
  • 13073_2020_744_MOESM2_ESM.xlsx, sheet 9
View BVdb publication page



Chinese siblings with hereditary medullary thyroid carcinoma caused by RET mutation: implications for RET oncogene detection.

Bmc Endocrine Disorders
Huang, Qin Q; Hu, Aihua A; Zhang, Mingsheng M
Publication Date: 2020-05-14

Variant appearance in text: RET: C634Y
PubMed Link: 32408902
Variant Present in the following documents:
  • Main text
View BVdb publication page



Primary hyperparathyroidism as first manifestation in multiple endocrine neoplasia type 2A: an international multicenter study.

Endocrine Connections
Larsen, Louise Vølund LV; Mirebeau-Prunier, Delphine D; Imai, Tsuneo T; Alvarez-Escola, Cristina C; Hasse-Lazar, Kornelia K; Censi, Simona S; Castroneves, Luciana A LA; Sakurai, Akihiro A; Kihara, Minoru M; Horiuchi, Kiyomi K; Barbu, Véronique Dorine VD; Borson-Chazot, Francoise F; Gimenez-Roqueplo, Anne-Paule AP; Pigny, Pascal P; Pinson, Stephane S; Wohllk, Nelson N; Eng, Charis C; Aydogan, Berna Imge BI; Saranath, Dhananjaya D; Dvorakova, Sarka S; Castinetti, Frederic F; Patocs, Attila A; Bergant, Damijan D; Links, Thera P TP; Peczkowska, Mariola M; Hoff, Ana O AO; Mian, Caterina C; Dwight, Trisha T; Jarzab, Barbara B; Neumann, Hartmut P H HPH; Robledo, Mercedes M; Uchino, Shinya S; Barlier, Anne A; Godballe, Christian C; Mathiesen, Jes Sloth JS
Publication Date: 2020-06

Variant appearance in text: RET: C634Y
PubMed Link: 32375120
Variant Present in the following documents:
  • Main text
View BVdb publication page



Bioisosteric Discovery of NPA101.3, a Second-Generation RET/VEGFR2 Inhibitor Optimized for Single-Agent Polypharmacology.

Journal Of Medicinal Chemistry
Moccia, Marialuisa M; Frett, Brendan B; Zhang, Lingtian L; Lakkaniga, Naga Rajiv NR; Briggs, David C DC; Chauhan, Rakhee R; Brescia, Annalisa A; Federico, Giorgia G; Yan, Wei W; Santoro, Massimo M; McDonald, Neil Q NQ; Li, Hong-Yu HY; Carlomagno, Francesca F
Publication Date: 2020-05-14

Variant appearance in text: RET: C634Y
PubMed Link: 32298114
Variant Present in the following documents:
  • Main text
  • jm9b01336_si_003.pdf
  • jm9b01336.pdf
View BVdb publication page



Glutaminases as a Novel Target for SDHB-Associated Pheochromocytomas/Paragangliomas.

Cancers
Sarkadi, Balazs B; Meszaros, Katalin K; Krencz, Ildiko I; Canu, Letizia L; Krokker, Lilla L; Zakarias, Sara S; Barna, Gabor G; Sebestyen, Anna A; Papay, Judit J; Hujber, Zoltan Z; Butz, Henriett H; Darvasi, Otto O; Igaz, Peter P; Doczi, Judit J; Luconi, Michaela M; Chinopoulos, Christos C; Patocs, Attila A
Publication Date: 2020-03-05

Variant appearance in text: RET: C634Y
PubMed Link: 32150977
Variant Present in the following documents:
  • Main text
  • cancers-12-00599.pdf
View BVdb publication page



Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Publication Date: 2020-07

Variant appearance in text: RET: C634Y
PubMed Link: 32107691
Variant Present in the following documents:
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12
View BVdb publication page



CRISPR/Cas system: An emerging technology in stem cell research.

World Journal Of Stem Cells
Valenti, Maria Teresa MT; Serena, Michela M; Carbonare, Luca Dalle LD; Zipeto, Donato D
Publication Date: 2019-11-26

Variant appearance in text: RET: C634Y
PubMed Link: 31768221
Variant Present in the following documents:
  • Main text
View BVdb publication page



Influencers on Thyroid Cancer Onset: Molecular Genetic Basis.

Genes
Luzón-Toro, Berta B; Fernández, Raquel María RM; Villalba-Benito, Leticia L; Torroglosa, Ana A; Antiñolo, Guillermo G; Borrego, Salud S
Publication Date: 2019-11-08

Variant appearance in text: MEN2A: C634Y
PubMed Link: 31717449
Variant Present in the following documents:
  • Main text
  • genes-10-00913.pdf
View BVdb publication page



Genetic Landscape of Somatic Mutations in a Large Cohort of Sporadic Medullary Thyroid Carcinomas Studied by Next-Generation Targeted Sequencing.

Iscience
Ciampi, Raffaele R; Romei, Cristina C; Ramone, Teresa T; Prete, Alessandro A; Tacito, Alessia A; Cappagli, Virginia V; Bottici, Valeria V; Viola, David D; Torregrossa, Liborio L; Ugolini, Clara C; Basolo, Fulvio F; Elisei, Rossella R
Publication Date: 2019-10-25

Variant appearance in text: RET: C634Y
PubMed Link: 31605946
Variant Present in the following documents:
  • Main text
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Inside the Black Box: What Makes SELEX Better?

Molecules (Basel, Switzerland)
Komarova, Natalia N; Kuznetsov, Alexander A
Publication Date: 2019-10-07

Variant appearance in text: RET: C634Y
PubMed Link: 31591283
Variant Present in the following documents:
  • Main text
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Long-Term Oncologic Outcomes After Curative Resection of Familial Medullary Thyroid Carcinoma.

Annals Of Surgical Oncology
Spanheimer, Philip M PM; Ganly, Ian I; Chou, Joanne J; Capanu, Marinela M; Ghossein, Ronald A RA; Tuttle, R Michael RM; Wong, Richard J RJ; Shaha, Ashok R AR; Untch, Brian R BR
Publication Date: 2019-12

Variant appearance in text: MEN2B: C634Y
PubMed Link: 31549322
Variant Present in the following documents:
  • Main text
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Twenty-Five Years Experience on RET Genetic Screening on Hereditary MTC: An Update on The Prevalence of Germline RET Mutations.

Genes
Elisei, Rossella R; Tacito, Alessia A; Ramone, Teresa T; Ciampi, Raffaele R; Bottici, Valeria V; Cappagli, Virginia V; Viola, David D; Matrone, Antonio A; Lorusso, Loredana L; Valerio, Laura L; Giani, Carlotta C; Campopiano, Cristina C; Prete, Alessandro A; Agate, Laura L; Molinaro, Eleonora E; Romei, Cristina C
Publication Date: 2019-09-10

Variant appearance in text: RET: C634Y
PubMed Link: 31510104
Variant Present in the following documents:
  • Main text
  • genes-10-00698.pdf
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REVEL and BayesDel outperform other in silico meta-predictors for clinical variant classification.

Scientific Reports
Tian, Yuan Y; Pesaran, Tina T; Chamberlin, Adam A; Fenwick, R Bryn RB; Li, Shuwei S; Gau, Chia-Ling CL; Chao, Elizabeth C EC; Lu, Hsiao-Mei HM; Black, Mary Helen MH; Qian, Dajun D
Publication Date: 2019-09-04

Variant appearance in text: RET: 1901G>A; C634Y
PubMed Link: 31484976
Variant Present in the following documents:
  • 41598_2019_49224_MOESM2_ESM.xlsx, sheet 1
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Comparison of Pheochromocytoma-Specific Morbidity and Mortality Among Adults With Bilateral Pheochromocytomas Undergoing Total Adrenalectomy vs Cortical-Sparing Adrenalectomy.

Jama Network Open
Neumann, Hartmut P H HPH; Tsoy, Uliana U; Bancos, Irina I; Amodru, Vincent V; Walz, Martin K MK; Tirosh, Amit A; Kaur, Ravinder Jeet RJ; McKenzie, Travis T; Qi, Xiaoping X; Bandgar, Tushar T; Petrov, Roman R; Yukina, Marina Y MY; Roslyakova, Anna A; van der Horst-Schrivers, Anouk N A ANA; Berends, Annika M A AMA; Hoff, Ana O AO; Castroneves, Luciana Audi LA; Ferrara, Alfonso Massimiliano AM; Rizzati, Silvia S; Mian, Caterina C; Dvorakova, Sarka S; Hasse-Lazar, Kornelia K; Kvachenyuk, Andrey A; Peczkowska, Mariola M; Loli, Paola P; Erenler, Feyza F; Krauss, Tobias T; Almeida, Madson Q MQ; Liu, Longfei L; Zhu, Feizhou F; Recasens, Mònica M; Wohllk, Nelson N; Corssmit, Eleonora P M EPM; Shafigullina, Zulfiya Z; Calissendorff, Jan J; Grozinsky-Glasberg, Simona S; Kunavisarut, Tada T; Schalin-Jäntti, Camilla C; Castinetti, Frederic F; Vlcek, Petr P; Beltsevich, Dmitry D; Egorov, Viacheslav I VI; Schiavi, Francesca F; Links, Thera P TP; Lechan, Ronald M RM; Bausch, Birke B; Young, William F WF; Eng, Charis C; ,
Publication Date: 2019-08-02

Variant appearance in text: RET: 1901G>A; Cys634Tyr
PubMed Link: 31397861
Variant Present in the following documents:
  • jamanetwopen-2-e198898-s001.pdf
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Retroposed copies of RET gene: a somatically acquired event in medullary thyroid carcinoma.

Bmc Medical Genomics
Bim, Larissa V LV; Navarro, Fábio C P FCP; Valente, Flávia O F FOF; Lima-Junior, José V JV; Delcelo, Rosana R; Dias-da-Silva, Magnus R MR; Maciel, Rui M B RMB; Galante, Pedro A F PAF; Cerutti, Janete M JM
Publication Date: 2019-07-09

Variant appearance in text: RET: C634Y
PubMed Link: 31288802
Variant Present in the following documents:
  • Main text
  • 12920_2019_Article_552.pdf
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