RET c.2194G>A ;(p.E732K)

Variant ID: 10-43612089-G-A

NM_020975.4(RET):c.2194G>A;(p.E732K)

This variant was identified in 8 publications

View GRCh38 version.




Publications:


Precision oncology for RET-related tumors.

Frontiers In Oncology
Verrienti, Antonella A; Grani, Giorgio G; Sponziello, Marialuisa M; Pecce, Valeria V; Damante, Giuseppe G; Durante, Cosimo C; Russo, Diego D; Filetti, Sebastiano S
Publication Date: 2022

Variant appearance in text: RET: E732K
PubMed Link: 36091144
Variant Present in the following documents:
  • Main text
  • fonc-12-992636.pdf
View BVdb publication page



Non-small-cell lung cancer: how to manage RET-positive disease.

Drugs In Context
Andrini, Elisa E; Mosca, Mirta M; Galvani, Linda L; Sperandi, Francesca F; Ricciuti, Biagio B; Metro, Giulio G; Lamberti, Giuseppe G
Publication Date: 2022

Variant appearance in text: RET: E732K
PubMed Link: 35912003
Variant Present in the following documents:
  • dic-2022-1-5.pdf
View BVdb publication page



Sporadic Medullary Thyroid Carcinoma: Towards a Precision Medicine.

Frontiers In Endocrinology
Matrone, Antonio A; Gambale, Carla C; Prete, Alessandro A; Elisei, Rossella R
Publication Date: 2022

Variant appearance in text: RET: E732K
PubMed Link: 35422765
Variant Present in the following documents:
  • Main text
  • fendo-13-864253.pdf
View BVdb publication page



Targeted activity of the small molecule kinase inhibitor Pz-1 towards RET and TRK kinases.

Scientific Reports
Moccia, Marialuisa M; Yang, Donglin D; Lakkaniga, Naga Rajiv NR; Frett, Brendan B; McConnell, Nicholas N; Zhang, Lingtian L; Brescia, Annalisa A; Federico, Giorgia G; Zhang, Lingzhi L; Salerno, Paolo P; Santoro, Massimo M; Li, Hong-Yu HY; Carlomagno, Francesca F
Publication Date: 2021-08-09

Variant appearance in text: RET: E732K
PubMed Link: 34373541
Variant Present in the following documents:
  • Main text
  • 41598_2021_Article_95612.pdf
View BVdb publication page



The L730V/I RET roof mutations display different activities toward pralsetinib and selpercatinib.

Npj Precision Oncology
Shen, Tao T; Hu, Xueqing X; Liu, Xuan X; Subbiah, Vivek V; Mooers, Blaine H M BHM; Wu, Jie J
Publication Date: 2021-06-07

Variant appearance in text: RET: E732K
PubMed Link: 34099825
Variant Present in the following documents:
  • Main text
  • 41698_2021_Article_188.pdf
View BVdb publication page



Longitudinal multi-gene panel assessment of circulating tumor DNA revealed tumor burden and molecular characteristics along treatment course of non-small cell lung cancer.

Translational Lung Cancer Research
Ho, Gloria Y F GYF; Wang, Tao T; Kwok, Hoi-Hin HH; Rasul, Rehana R; Peila, Rita R; Guzman, Maria M; Ip, Mary S M MSM; Lam, David C L DCL
Publication Date: 2020-10

Variant appearance in text: RET: E732K
PubMed Link: 33209609
Variant Present in the following documents:
  • Main text
  • tlcr-09-05-1873.pdf
View BVdb publication page



Refinement of evolutionary medicine predictions based on clinical evidence for the manifestations of Mendelian diseases.

Scientific Reports
Šimčíková, Daniela D; Heneberg, Petr P
Publication Date: 2019-12-09

Variant appearance in text: RET: E732K
PubMed Link: 31819097
Variant Present in the following documents:
  • 41598_2019_54976_MOESM2_ESM.xlsx, sheet 8
View BVdb publication page



Drug resistance profiles of mutations in the RET kinase domain.

British Journal Of Pharmacology
Liu, Xuan X; Shen, Tao T; Mooers, Blaine H M BHM; Hilberg, Frank F; Wu, Jie J
Publication Date: 2018-09

Variant appearance in text: RET: E732K
PubMed Link: 29908090
Variant Present in the following documents:
  • Main text
View BVdb publication page