RET c.2410G>C ;(p.V804L)

Variant ID: 10-43614996-G-C

NM_020975.4(RET):c.2410G>C;(p.V804L)

This variant was identified in 164 publications

View GRCh38 version.




Publications:


Characterization of p38α autophosphorylation inhibitors that target the non-canonical activation pathway.

Nature Communications
González, Lorena L; Díaz, Lucía L; Pous, Joan J; Baginski, Blazej B; Duran-Corbera, Anna A; Scarpa, Margherita M; Brun-Heath, Isabelle I; Igea, Ana A; Martin-Malpartida, Pau P; Ruiz, Lidia L; Pallara, Chiara C; Esguerra, Mauricio M; Colizzi, Francesco F; Mayor-Ruiz, Cristina C; Biondi, Ricardo M RM; Soliva, Robert R; Macias, Maria J MJ; Orozco, Modesto M; Nebreda, Angel R AR
Publication Date: 2023-06-12

Variant appearance in text: RET: V804L
PubMed Link: 37308482
Variant Present in the following documents:
  • 41467_2023_39051_MOESM3_ESM.xlsx, sheet 5
View BVdb publication page



Primary Hyperparathyroidism in Multiple Endocrine Neoplasia Type 2A in Denmark: A Nationwide Population-Based Retrospective Study in Denmark 1930-2021.

Cancers
Holm, Magnus M; Vestergaard, Peter P; Poulsen, Morten Møller MM; Rasmussen, Åse Krogh ÅK; Feldt-Rasmussen, Ulla U; Bay, Mette M; Rolighed, Lars L; Londero, Stefano S; Pedersen, Henrik Baymler HB; Hahn, Christoffer Holst CH; Rask, Klara Bay KB; Nielsen, Heidi Hvid HH; Gaustadnes, Mette M; Rossing, Maria Caroline MC; Hermann, Anne Pernille AP; Godballe, Christian C; Mathiesen, Jes Sloth JS
Publication Date: 2023-04-02

Variant appearance in text: RET: Val804Leu
PubMed Link: 37046785
Variant Present in the following documents:
  • Main text
  • cancers-15-02125.pdf
View BVdb publication page



Discovery of an In Vivo Chemical Probe for BCL6 Inhibition by Optimization of Tricyclic Quinolinones.

Journal Of Medicinal Chemistry
Harnden, Alice C AC; Davis, Owen A OA; Box, Gary M GM; Hayes, Angela A; Johnson, Louise D LD; Henley, Alan T AT; de Haven Brandon, Alexis K AK; Valenti, Melanie M; Cheung, Kwai-Ming J KJ; Brennan, Alfie A; Huckvale, Rosemary R; Pierrat, Olivier A OA; Talbot, Rachel R; Bright, Michael D MD; Akpinar, Hafize Aysin HA; Miller, Daniel S J DSJ; Tarantino, Dalia D; Gowan, Sharon S; de Klerk, Selby S; McAndrew, Peter Craig PC; Le Bihan, Yann-Vaï YV; Meniconi, Mirco M; Burke, Rosemary R; Kirkin, Vladimir V; van Montfort, Rob L M RLM; Raynaud, Florence I FI; Rossanese, Olivia W OW; Bellenie, Benjamin R BR; Hoelder, Swen S
Publication Date: 2023-04-07

Variant appearance in text: RET: V804L
PubMed Link: 37026591
Variant Present in the following documents:
  • jm3c00155_si_002.xlsx, sheet 2
View BVdb publication page



Personalized Systemic Therapies in Hereditary Cancer Syndromes.

Genes
Mastrodomenico, Luciana L; Piombino, Claudia C; Riccò, Beatrice B; Barbieri, Elena E; Venturelli, Marta M; Piacentini, Federico F; Dominici, Massimo M; Cortesi, Laura L; Toss, Angela A
Publication Date: 2023-03-09

Variant appearance in text: RET: V804L
PubMed Link: 36980956
Variant Present in the following documents:
  • Main text
  • genes-14-00684.pdf
View BVdb publication page



Immune and pathologic responses in patients with localized prostate cancer who received daratumumab (anti-CD38) or edicotinib (CSF-1R inhibitor).

Journal For Immunotherapy Of Cancer
Siddiqui, Bilal A BA; Chapin, Brian F BF; Jindal, Sonali S; Duan, Fei F; Basu, Sreyashi S; Yadav, Shalini S SS; Gu, Ai-Di AD; Espejo, Alexsandra B AB; Kinder, Michelle M; Pettaway, Curtis A CA; Ward, John F JF; Tidwell, Rebecca S S RSS; Troncoso, Patricia P; Corn, Paul G PG; Logothetis, Christopher J CJ; Knoblauch, Roland R; Hutnick, Natalie N; Gottardis, Marco M; Drake, Charles G CG; Sharma, Padmanee P; Subudhi, Sumit K SK
Publication Date: 2023-03

Variant appearance in text: RET: V804L
PubMed Link: 36948506
Variant Present in the following documents:
  • jitc-2022-006262supp001.pdf
View BVdb publication page



Deep Annotation of Donated Chemical Probes (DCP) in Organotypic Human Liver Cultures and Patient-Derived Organoids from Tumor and Normal Colorectum.

Acs Chemical Biology
Tredup, Claudia C; Ndreshkjana, Benardina B; Schneider, Natalie S NS; Tjaden, Amelie A; Kemas, Aurino M AM; Youhanna, Sonia S; Lauschke, Volker M VM; Berger, Benedict-Tilman BT; Krämer, Andreas A; Berger, Lena M LM; Röhm, Sandra S; Knapp, Stefan S; Farin, Henner F HF; Müller, Susanne S
Publication Date: 2023-03-21

Variant appearance in text: RET: V804L
PubMed Link: 36944371
Variant Present in the following documents:
  • cb2c00877_si_004.xlsx, sheet 1
View BVdb publication page



Investigation of the anti-tumor mechanism of tirabrutinib, a highly selective Bruton's tyrosine kinase inhibitor, by phosphoproteomics and transcriptomics.

Plos One
Kozaki, Ryohei R; Yasuhiro, Tomoko T; Kato, Hikaru H; Murai, Jun J; Hotta, Shingo S; Ariza, Yuko Y; Sakai, Shunsuke S; Fujikawa, Ryu R; Yoshida, Takao T
Publication Date: 2023

Variant appearance in text: RET: V804L
PubMed Link: 36897912
Variant Present in the following documents:
  • pone.0282166.s009.xlsx, sheet 1
View BVdb publication page



Activation of cancer immunotherapy by nanomedicine.

Frontiers In Pharmacology
Wang, Lijuan L; Xu, Henan H; Weng, Lili L; Sun, Jin J; Jin, Ye Y; Xiao, Chunping C
Publication Date: 2022

Variant appearance in text: RET: V804L
PubMed Link: 36618938
Variant Present in the following documents:
  • Main text
  • fphar-13-1041073.pdf
View BVdb publication page



Targeted therapy of RET fusion-positive non-small cell lung cancer.

Frontiers In Oncology
Shen, Zixiong Z; Qiu, Binxu B; Li, Lin L; Yang, Bo B; Li, Guanghu G
Publication Date: 2022

Variant appearance in text: RET: V804L
PubMed Link: 36582799
Variant Present in the following documents:
  • Main text
  • fonc-12-1033484.pdf
View BVdb publication page



Temporal trends in referrals of RET gene carriers for neck surgery to a tertiary surgical center in the era of international management guidelines.

Endocrine
Machens, Andreas A; Lorenz, Kerstin K; Huessler, Eva-Maria EM; Stang, Andreas A; Weber, Frank F; Dralle, Henning H
Publication Date: 2022-12-02

Variant appearance in text: RET: Val804Leu
PubMed Link: 36456885
Variant Present in the following documents:
  • Main text
  • 12020_2022_Article_3273.pdf
View BVdb publication page



Clinical exome-based panel testing for medically actionable secondary findings in a cohort of 383 Italian participants.

Frontiers In Genetics
Martone, Stefania S; Buonagura, Autilia Tommasina AT; Marra, Roberta R; Rosato, Barbara Eleni BE; Del Giudice, Federica F; Bonfiglio, Ferdinando F; Capasso, Mario M; Iolascon, Achille A; Andolfo, Immacolata I; Russo, Roberta R
Publication Date: 2022

Variant appearance in text: rs79658334
PubMed Link: 36437915
Variant Present in the following documents:
  • Main text
View BVdb publication page



CRISPR/Cas9 RET Gene Knockout in Medullary Thyroid Carcinoma Cell-lines: Optimization and Validation.

Iranian Journal Of Public Health
Zarif-Yeganeh, Marjan M; Farhud, Dariush D DD; Rahimpour, Azam A; Sheikholeslami, Sara S; Shivaei, Setareh S; Hedayati, Mehdi M
Publication Date: 2022-05

Variant appearance in text: RET: V804L
PubMed Link: 36407731
Variant Present in the following documents:
  • Main text
  • IJPH-51-1084.pdf
View BVdb publication page



VIP152 is a selective CDK9 inhibitor with pre-clinical in vitro and in vivo efficacy in chronic lymphocytic leukemia.

Leukemia
Sher, Steven S; Whipp, Ethan E; Walker, Janek J; Zhang, Pu P; Beaver, Larry L; Williams, Katie K; Orwick, Shelley S; Ravikrishnan, Janani J; Walker, Brandi B; Perry, Elizabeth E; Gregory, Charles C; Purcell, Matthew M; Pan, Alexander A; Yan, Pearlly P; Alinari, Lapo L; Johnson, Amy J AJ; Frigault, Melanie M MM; Greer, Joy M JM; Hamdy, Ahmed A; Izumi, Raquel R; Mo, Xiaokui X; Sampath, Deepa D; Woyach, Jennifer J; Blachly, James J; Byrd, John C JC; Lapalombella, Rosa R
Publication Date: 2022-11-14

Variant appearance in text: RET: V804L
PubMed Link: 36376377
Variant Present in the following documents:
  • 41375_2022_1758_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



RET Proto-Oncogene-Not Such an Obvious Starting Point in Cancer Therapy.

Cancers
Kucharczyk, Tomasz T; Krawczyk, Paweł P; Kowalski, Dariusz M DM; Płużański, Adam A; Kubiatowski, Tomasz T; Kalinka, Ewa E
Publication Date: 2022-10-27

Variant appearance in text: RET: V804L
PubMed Link: 36358717
Variant Present in the following documents:
  • Main text
  • cancers-14-05298.pdf
View BVdb publication page



Brain-restricted mTOR inhibition with binary pharmacology.

Nature
Zhang, Ziyang Z; Fan, Qiwen Q; Luo, Xujun X; Lou, Kevin K; Weiss, William A WA; Shokat, Kevan M KM
Publication Date: 2022-09

Variant appearance in text: RET: V804L
PubMed Link: 36104566
Variant Present in the following documents:
  • 41586_2022_5213_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



RET fusions as primary oncogenic drivers and secondary acquired resistance to EGFR tyrosine kinase inhibitors in patients with non-small-cell lung cancer.

Journal Of Translational Medicine
Wang, Chunyue C; Zhang, Zhenlong Z; Sun, Yulan Y; Wang, Song S; Wu, Mengmeng M; Ou, Qiuxiang Q; Xu, Yang Y; Chen, Zhiming Z; Shao, Yang Y; Liu, Hong H; Hou, Peifeng P
Publication Date: 2022-09-04

Variant appearance in text: RET: V804L
PubMed Link: 36059009
Variant Present in the following documents:
  • Main text
  • 12967_2022_Article_3593.pdf
View BVdb publication page



Designing Novel BCR-ABL Inhibitors for Chronic Myeloid Leukemia with Improved Cardiac Safety.

Journal Of Medicinal Chemistry
Pandrala, Mallesh M; Bruyneel, Arne Antoon N AAN; Hnatiuk, Anna P AP; Mercola, Mark M; Malhotra, Sanjay V SV
Publication Date: 2022-08-25

Variant appearance in text: RET: V804L
PubMed Link: 35944901
Variant Present in the following documents:
  • jm1c01853_si_003.xlsx, sheet 1
View BVdb publication page



Target Therapy in Thyroid Cancer: Current Challenge in Clinical Use of Tyrosine Kinase Inhibitors and Management of Side Effects.

Frontiers In Endocrinology
Puliafito, Ivana I; Esposito, Francesca F; Prestifilippo, Angela A; Marchisotta, Stefania S; Sciacca, Dorotea D; Vitale, Maria Paola MP; Giuffrida, Dario D
Publication Date: 2022

Variant appearance in text: RET: V804L
PubMed Link: 35872981
Variant Present in the following documents:
  • Main text
  • fendo-13-860671.pdf
View BVdb publication page



Comprehensive Assessment of Indian Variations in the Druggable Kinome Landscape Highlights Distinct Insights at the Sequence, Structure and Pharmacogenomic Stratum.

Frontiers In Pharmacology
Panda, Gayatri G; Mishra, Neha N; Sharma, Disha D; Kutum, Rintu R; Bhoyar, Rahul C RC; Jain, Abhinav A; Imran, Mohamed M; Senthilvel, Vigneshwar V; Divakar, Mohit Kumar MK; Mishra, Anushree A; Garg, Parth P; Banerjee, Priyanka P; Sivasubbu, Sridhar S; Scaria, Vinod V; Ray, Arjun A
Publication Date: 2022

Variant appearance in text: N/A
PubMed Link: 35865963
Variant Present in the following documents:
View BVdb publication page



Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance.

Nature Communications
Wrobel, Lidia L; Hill, Sandra M SM; Djajadikerta, Alvin A; Fernandez-Estevez, Marian M; Karabiyik, Cansu C; Ashkenazi, Avraham A; Barratt, Victoria J VJ; Stamatakou, Eleanna E; Gunnarsson, Anders A; Rasmusson, Timothy T; Miele, Eric W EW; Beaton, Nigel N; Bruderer, Roland R; Feng, Yuehan Y; Reiter, Lukas L; Castaldi, M Paola MP; Jarvis, Rebecca R; Tan, Keith K; Bürli, Roland W RW; Rubinsztein, David C DC
Publication Date: 2022-07-16

Variant appearance in text: RET: V804L
PubMed Link: 35842429
Variant Present in the following documents:
  • 41467_2022_31905_MOESM5_ESM.xlsx, sheet 1
View BVdb publication page



Reengineering Ponatinib to Minimize Cardiovascular Toxicity.

Cancer Research
Hnatiuk, Anna P AP; Bruyneel, Arne A N AAN; Tailor, Dhanir D; Pandrala, Mallesh M; Dheeraj, Arpit A; Li, Wenqi W; Serrano, Ricardo R; Feyen, Dries A M DAM; Vu, Michelle M MM; Amatya, Prashila P; Gupta, Saloni S; Nakauchi, Yusuke Y; Morgado, Isabel I; Wiebking, Volker V; Liao, Ronglih R; Porteus, Matthew H MH; Majeti, Ravindra R; Malhotra, Sanjay V SV; Mercola, Mark M
Publication Date: 2022-08-03

Variant appearance in text: RET: V804L
PubMed Link: 35763671
Variant Present in the following documents:
  • can-21-3652_supplementary_table_s1_suppst1.xls, sheet 2
View BVdb publication page



Improved Binding Affinity and Pharmacokinetics Enable Sustained Degradation of BCL6 In Vivo.

Journal Of Medicinal Chemistry
Huckvale, Rosemary R; Harnden, Alice C AC; Cheung, Kwai-Ming J KJ; Pierrat, Olivier A OA; Talbot, Rachel R; Box, Gary M GM; Henley, Alan T AT; de Haven Brandon, Alexis K AK; Hallsworth, Albert E AE; Bright, Michael D MD; Akpinar, Hafize Aysin HA; Miller, Daniel S J DSJ; Tarantino, Dalia D; Gowan, Sharon S; Hayes, Angela A; Gunnell, Emma A EA; Brennan, Alfie A; Davis, Owen A OA; Johnson, Louise D LD; de Klerk, Selby S; McAndrew, Craig C; Le Bihan, Yann-Vaï YV; Meniconi, Mirco M; Burke, Rosemary R; Kirkin, Vladimir V; van Montfort, Rob L M RLM; Raynaud, Florence I FI; Rossanese, Olivia W OW; Bellenie, Benjamin R BR; Hoelder, Swen S
Publication Date: 2022-06-23

Variant appearance in text: RET: V804L
PubMed Link: 35653645
Variant Present in the following documents:
  • jm1c02175_si_002.xlsx, sheet 2
View BVdb publication page



Sporadic Medullary Thyroid Carcinoma: Towards a Precision Medicine.

Frontiers In Endocrinology
Matrone, Antonio A; Gambale, Carla C; Prete, Alessandro A; Elisei, Rossella R
Publication Date: 2022

Variant appearance in text: RET: V804L
PubMed Link: 35422765
Variant Present in the following documents:
  • Main text
  • fendo-13-864253.pdf
View BVdb publication page



Whole-genome sequencing of 1,171 elderly admixed individuals from São Paulo, Brazil.

Nature Communications
Naslavsky, Michel S MS; Scliar, Marilia O MO; Yamamoto, Guilherme L GL; Wang, Jaqueline Yu Ting JYT; Zverinova, Stepanka S; Karp, Tatiana T; Nunes, Kelly K; Ceroni, José Ricardo Magliocco JRM; de Carvalho, Diego Lima DL; da Silva Simões, Carlos Eduardo CE; Bozoklian, Daniel D; Nonaka, Ricardo R; Dos Santos Brito Silva, Nayane N; da Silva Souza, Andreia A; de Souza Andrade, Heloísa H; Passos, Marília Rodrigues Silva MRS; Castro, Camila Ferreira Bannwart CFB; Mendes-Junior, Celso T CT; Mercuri, Rafael L V RLV; Miller, Thiago L A TLA; Buzzo, Jose Leonel JL; Rego, Fernanda O FO; Araújo, Nathalia M NM; Magalhães, Wagner C S WCS; Mingroni-Netto, Regina Célia RC; Borda, Victor V; Guio, Heinner H; Rojas, Carlos P CP; Sanchez, Cesar C; Caceres, Omar O; Dean, Michael M; Barreto, Mauricio L ML; Lima-Costa, Maria Fernanda MF; Horta, Bernardo L BL; Tarazona-Santos, Eduardo E; Meyer, Diogo D; Galante, Pedro A F PAF; Guryev, Victor V; Castelli, Erick C EC; Duarte, Yeda A O YAO; Passos-Bueno, Maria Rita MR; Zatz, Mayana M
Publication Date: 2022-03-04

Variant appearance in text: rs79658334
PubMed Link: 35246524
Variant Present in the following documents:
  • 41467_2022_28648_MOESM9_ESM.xlsx, sheet 1
View BVdb publication page



Multiple endocrine neoplasia 2: an overview.

Therapeutic Advances In Chronic Disease
Saravana-Bawan, B B; Pasternak, J D JD
Publication Date: 2022

Variant appearance in text: RET: Val804Leu
PubMed Link: 35237400
Variant Present in the following documents:
  • Main text
  • 10.1177_20406223221079246.pdf
View BVdb publication page



Emerging Biomarkers in Thyroid Practice and Research.

Cancers
Agarwal, Shipra S; Bychkov, Andrey A; Jung, Chan-Kwon CK
Publication Date: 2021-12-31

Variant appearance in text: RET: V804L
PubMed Link: 35008368
Variant Present in the following documents:
  • Main text
View BVdb publication page



Emerging Biomarkers in Thyroid Practice and Research.

Cancers
Agarwal, Shipra S; Bychkov, Andrey A; Jung, Chan-Kwon CK
Publication Date: 2021-12-31

Variant appearance in text: RET: V804L
PubMed Link: 35008368
Variant Present in the following documents:
  • Main text
View BVdb publication page



Therapeutic advances in non-small cell lung cancer: Focus on clinical development of targeted therapy and immunotherapy.

Medcomm
Cheng, Yuan Y; Zhang, Tao T; Xu, Qing Q
Publication Date: 2021-12

Variant appearance in text: RET: V804L
PubMed Link: 34977873
Variant Present in the following documents:
  • Main text
  • MCO2-2-692.pdf
View BVdb publication page



Nicotinamide promotes cardiomyocyte derivation and survival through kinase inhibition in human pluripotent stem cells.

Cell Death & Disease
Meng, Ya Y; Song, Chengcheng C; Ren, Zhili Z; Li, Xiaohong X; Yang, Xiangyu X; Ai, Nana N; Yang, Yang Y; Wang, Dongjin D; Zhan, Meixiao M; Wang, Jiaxian J; Lei, Chon Lok CL; Liu, Weiwei W; Ge, Wei W; Lu, Ligong L; Chen, Guokai G
Publication Date: 2021-11-29

Variant appearance in text: RET: V804L
PubMed Link: 34845199
Variant Present in the following documents:
  • 41419_2021_4395_MOESM9_ESM.xlsx, sheet 1
View BVdb publication page



[Advances in the Treatment of RET Fusion-Positive Advanced Non-Small-Cell Lung Cancer].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Gao, Qingyun Q; Su, Junwei J; Xiao, Faman F; Lin, Xiaocheng X; Yang, Jinji J
Publication Date: 2021-11-08

Variant appearance in text: RET: V804L
PubMed Link: 34743497
Variant Present in the following documents:
  • Main text
  • zgfazz-24-12-853.pdf
View BVdb publication page



[Advances in the Treatment of RET Fusion-positive Advanced Non-small Cell Lung Cancer].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Gao, Qingyun Q; Su, Junwei J; Xiao, Faman F; Lin, Xiaocheng X; Yang, Jinji J
Publication Date: 2021-12-20

Variant appearance in text: RET: V804L
PubMed Link: 34743497
Variant Present in the following documents:
  • Main text
  • zgfazz-24-12-853.pdf
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: RET: V804L
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



RET Fusion: Joining the Ranks of Targetable Molecular Drivers in NSCLC.

Jto Clinical And Research Reports
Osta, Badi El BE; Ramalingam, Suresh S SS
Publication Date: 2020-09

Variant appearance in text: RET: V804L
PubMed Link: 34589946
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Targeted Therapy for RET Fusion Lung Cancer: Breakthrough and Unresolved Issue.

Frontiers In Oncology
Takamori, Shinkichi S; Matsubara, Taichi T; Haratake, Naoki N; Toyokawa, Gouji G; Fujishita, Takatoshi T; Toyozawa, Ryo R; Ito, Kensaku K; Yamaguchi, Masafumi M; Taguchi, Kenichi K; Okamoto, Tatsuro T; Seto, Takashi T
Publication Date: 2021

Variant appearance in text: RET: V804L
PubMed Link: 34497761
Variant Present in the following documents:
  • Main text
View BVdb publication page



Update on Targeted Therapy in Medullary Thyroid Cancer.

Frontiers In Endocrinology
Okafor, Christian C; Hogan, Julie J; Raygada, Margarita M; Thomas, Barbara J BJ; Akshintala, Srivandana S; Glod, John W JW; Del Rivero, Jaydira J
Publication Date: 2021

Variant appearance in text: RET: V804L
PubMed Link: 34489865
Variant Present in the following documents:
  • Main text
  • fendo-12-708949.pdf
View BVdb publication page



Targeted activity of the small molecule kinase inhibitor Pz-1 towards RET and TRK kinases.

Scientific Reports
Moccia, Marialuisa M; Yang, Donglin D; Lakkaniga, Naga Rajiv NR; Frett, Brendan B; McConnell, Nicholas N; Zhang, Lingtian L; Brescia, Annalisa A; Federico, Giorgia G; Zhang, Lingzhi L; Salerno, Paolo P; Santoro, Massimo M; Li, Hong-Yu HY; Carlomagno, Francesca F
Publication Date: 2021-08-09

Variant appearance in text: RET: V804L
PubMed Link: 34373541
Variant Present in the following documents:
  • Main text
  • 41598_2021_Article_95612.pdf
View BVdb publication page



Discovery and Characterization of Selective and Ligand-Efficient DYRK Inhibitors.

Journal Of Medicinal Chemistry
Henderson, Scott H SH; Sorrell, Fiona F; Bennett, James J; Fedorov, Oleg O; Hanley, Marcus T MT; Godoi, Paulo H PH; Ruela de Sousa, Roberta R; Robinson, Sean S; Ashall-Kelly, Alexander A; Hopkins Navratilova, Iva I; Walter, Daryl S DS; Elkins, Jonathan M JM; Ward, Simon E SE
Publication Date: 2021-08-12

Variant appearance in text: RET: V804L
PubMed Link: 34342227
Variant Present in the following documents:
  • jm1c01115_si_002.xlsx, sheet 1
  • jm1c01115_si_002.xlsx, sheet 5
  • jm1c01115_si_002.xlsx, sheet 9
  • jm1c01115_si_002.xlsx, sheet 7
  • jm1c01115_si_002.xlsx, sheet 14
  • jm1c01115_si_002.xlsx, sheet 12
  • jm1c01115_si_002.xlsx, sheet 3
  • jm1c01115_si_002.xlsx, sheet 11
  • jm1c01115_si_002.xlsx, sheet 13
  • jm1c01115_si_002.xlsx, sheet 10
  • jm1c01115_si_002.xlsx, sheet 2
  • jm1c01115_si_002.xlsx, sheet 8
  • jm1c01115_si_002.xlsx, sheet 4
  • jm1c01115_si_002.xlsx, sheet 6
View BVdb publication page



Phosphorylated WNK kinase networks in recoded bacteria recapitulate physiological function.

Cell Reports
Schiapparelli, Paula P; Pirman, Natasha L NL; Mohler, Kyle K; Miranda-Herrera, Pierre A PA; Zarco, Natanael N; Kilic, Onur O; Miller, Chad C; Shah, Sagar R SR; Rogulina, Svetlana S; Hungerford, William W; Abriola, Laura L; Hoyer, Denton D; Turk, Benjamin E BE; Guerrero-Cázares, Hugo H; Isaacs, Farren J FJ; Quiñones-Hinojosa, Alfredo A; Levchenko, Andre A; Rinehart, Jesse J
Publication Date: 2021-07-20

Variant appearance in text: RET: V804L
PubMed Link: 34289367
Variant Present in the following documents:
  • NIHMS1726840-supplement-2.xlsx, sheet 1
View BVdb publication page



Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes.

Journal Of Medicinal Chemistry
Eduful, Benjamin J BJ; O'Byrne, Sean N SN; Temme, Louisa L; Asquith, Christopher R M CRM; Liang, Yi Y; Picado, Alfredo A; Pilotte, Joseph R JR; Hossain, Mohammad Anwar MA; Wells, Carrow I CI; Zuercher, William J WJ; Catta-Preta, Carolina M C CMC; Zonzini Ramos, Priscila P; Santiago, André de S AS; Couñago, Rafael M RM; Langendorf, Christopher G CG; Nay, Kévin K; Oakhill, Jonathan S JS; Pulliam, Thomas L TL; Lin, Chenchu C; Awad, Dominik D; Willson, Timothy M TM; Frigo, Daniel E DE; Scott, John W JW; Drewry, David H DH
Publication Date: 2021-08-12

Variant appearance in text: RET: V804L
PubMed Link: 34264658
Variant Present in the following documents:
  • jm0c02274_si_003.xlsx, sheet 1
View BVdb publication page



Medullary Thyroid Cancer - Feature Review and Update on Systemic Treatment.

Acta Clinica Croatica
Dabelić, Nina N; Jukić, Tomislav T; Fröbe, Ana A
Publication Date: 2020-06

Variant appearance in text: RET: V804L
PubMed Link: 34219884
Variant Present in the following documents:
  • Main text
  • acc-59-s1-50.pdf
View BVdb publication page



[Research Progress of Fusion Genes RET in Non-small Cell Lung Cancer].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Zheng, Yujun Y; Jiang, Wei W; Chen, Dongyan D; Li, Yanjun Y; Dai, Lulu L; Huang, Lei L; Wang, Mingji M
Publication Date: 2021-08-20

Variant appearance in text: RET: V804L
PubMed Link: 34120433
Variant Present in the following documents:
  • Main text
View BVdb publication page



Evolution of kinase polypharmacology across HSP90 drug discovery.

Cell Chemical Biology
Antolin, Albert A AA; Clarke, Paul A PA; Collins, Ian I; Workman, Paul P; Al-Lazikani, Bissan B
Publication Date: 2021-10-21

Variant appearance in text: RET: V804L
PubMed Link: 34077750
Variant Present in the following documents:
  • mmc4.xlsx, sheet 1
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Profiling Oncogenic Germline Mutations in Unselected Chinese Lung Cancer Patients.

Frontiers In Oncology
Yang, Jie J; Li, Hefei H; Li, Ben B; Li, Wei W; Guo, Qiang Q; Hu, Ling L; Song, Zizheng Z; Zhou, Bin B
Publication Date: 2021

Variant appearance in text: RET: V804L
PubMed Link: 33898318
Variant Present in the following documents:
  • Main text
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Chasing the Target: New Phenomena of Resistance to Novel Selective RET Inhibitors in Lung Cancer. Updated Evidence and Future Perspectives.

Cancers
Fancelli, Sara S; Caliman, Enrico E; Mazzoni, Francesca F; Brugia, Marco M; Castiglione, Francesca F; Voltolini, Luca L; Pillozzi, Serena S; Antonuzzo, Lorenzo L
Publication Date: 2021-03-04

Variant appearance in text: RET: V804L
PubMed Link: 33806299
Variant Present in the following documents:
  • cancers-13-01091.pdf
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