Publications:

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Machine learning driven drug repurposing strategy for identification of potential RET inhibitors against non-small cell lung cancer.

Medical Oncology (Northwood, London, England)

Ramesh, Priyanka P; Karuppasamy, Ramanathan R; Veerappapillai, Shanthi S

Publication Date: 2022-12-21

Variant appearance in text: RET: G810A

PubMed Link: 36542155

Variant Present in the following documents:

• Main text
• 12032_2022_Article_1924.pdf

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Precision oncology for RET-related tumors.

Frontiers In Oncology

Verrienti, Antonella A; Grani, Giorgio G; Sponziello, Marialuisa M; Pecce, Valeria V; Damante, Giuseppe G; Durante, Cosimo C; Russo, Diego D; Filetti, Sebastiano S

Publication Date: 2022

Variant appearance in text: RET: G810A

PubMed Link: 36091144

Variant Present in the following documents:

• Main text
• fonc-12-992636.pdf

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Non-small-cell lung cancer: how to manage RET-positive disease.

Drugs In Context

Andrini, Elisa E; Mosca, Mirta M; Galvani, Linda L; Sperandi, Francesca F; Ricciuti, Biagio B; Metro, Giulio G; Lamberti, Giuseppe G

Publication Date: 2022

Variant appearance in text: RET: G810A

PubMed Link: 35912003

Variant Present in the following documents:

• dic-2022-1-5.pdf

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RET kinase inhibitors for RET-altered thyroid cancers.

Therapeutic Advances In Medical Oncology

Vodopivec, Danica M DM; Hu, Mimi I MI

Publication Date: 2022

Variant appearance in text: RET: G810A

PubMed Link: 35756966

Variant Present in the following documents:

• 10.1177_17588359221101691.pdf

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Research Progress on RET Fusion in Non-Small-Cell Lung Cancer.

Frontiers In Oncology

Zhao, Lu L; Mei, Qingyun Q; Yu, Yongchao Y; Wang, Na N; Zhang, Dou D; Liao, Dongying D; Zuo, Jinhui J; Xie, Hongxia H; Jia, Yingjie Y; Kong, Fanming F

Publication Date: 2022

Variant appearance in text: RET: G810A

PubMed Link: 35707347

Variant Present in the following documents:

• Main text
• fonc-12-894214.pdf

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Designing Novel Compounds for the Treatment and Management of RET-Positive Non-Small Cell Lung Cancer-Fragment Based Drug Design Strategy.

Molecules (Basel, Switzerland)

Ramesh, Priyanka P; Veerappapillai, Shanthi S

Publication Date: 2022-02-28

Variant appearance in text: RET: G810A

PubMed Link: 35268691

Variant Present in the following documents:

• Main text
• molecules-27-01590.pdf

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Targeted activity of the small molecule kinase inhibitor Pz-1 towards RET and TRK kinases.

Scientific Reports

Moccia, Marialuisa M; Yang, Donglin D; Lakkaniga, Naga Rajiv NR; Frett, Brendan B; McConnell, Nicholas N; Zhang, Lingtian L; Brescia, Annalisa A; Federico, Giorgia G; Zhang, Lingzhi L; Salerno, Paolo P; Santoro, Massimo M; Li, Hong-Yu HY; Carlomagno, Francesca F

Publication Date: 2021-08-09

Variant appearance in text: RET: G810A

PubMed Link: 34373541

Variant Present in the following documents:

• Main text
• 41598_2021_Article_95612.pdf

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[Research Progress of Fusion Genes RET in Non-small Cell Lung Cancer].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer

Zheng, Yujun Y; Jiang, Wei W; Chen, Dongyan D; Li, Yanjun Y; Dai, Lulu L; Huang, Lei L; Wang, Mingji M

Publication Date: 2021-08-20

Variant appearance in text: RET: G810A

PubMed Link: 34120433

Variant Present in the following documents:

• Main text
• zgfazz-24-8-591.pdf

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Chasing the Target: New Phenomena of Resistance to Novel Selective RET Inhibitors in Lung Cancer. Updated Evidence and Future Perspectives.

Cancers

Fancelli, Sara S; Caliman, Enrico E; Mazzoni, Francesca F; Brugia, Marco M; Castiglione, Francesca F; Voltolini, Luca L; Pillozzi, Serena S; Antonuzzo, Lorenzo L

Publication Date: 2021-03-04

Variant appearance in text: RET: G810A

PubMed Link: 33806299

Variant Present in the following documents:

• Main text
• cancers-13-01091.pdf

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Overcoming TKI resistance in fusion-driven NSCLC: new generation inhibitors and rationale for combination strategies.

Translational Lung Cancer Research

Russo, Alessandro A; Cardona, Andrés F AF; Caglevic, Christian C; Manca, Paolo P; Ruiz-Patiño, Alejandro A; Arrieta, Oscar O; Rolfo, Christian C

Publication Date: 2020-12

Variant appearance in text: RET: G810A

PubMed Link: 33489820

Variant Present in the following documents:

• Main text

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Decade in review: a new era for RET-rearranged lung cancers.

Translational Lung Cancer Research

Choudhury, Noura J NJ; Drilon, Alexander A

Publication Date: 2020-12

Variant appearance in text: RET: G810A

PubMed Link: 33489819

Variant Present in the following documents:

• Main text

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5P Strategies for Management of Multiple Endocrine Neoplasia Type 2: A Paradigm of Precision Medicine.

Frontiers In Endocrinology

Li, Shu-Yuan SY; Ding, Yi-Qiang YQ; Si, You-Liang YL; Ye, Mu-Jin MJ; Xu, Chen-Ming CM; Qi, Xiao-Ping XP

Publication Date: 2020

Variant appearance in text: RET: G810A

PubMed Link: 33071967

Variant Present in the following documents:

• Main text
• fendo-11-543246.pdf

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Advances in Targeting RET-Dependent Cancers.

Cancer Discovery

Subbiah, Vivek V; Cote, Gilbert J GJ

Publication Date: 2020-04

Variant appearance in text: RET: G810A

PubMed Link: 32094155

Variant Present in the following documents:

• Main text

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Refinement of evolutionary medicine predictions based on clinical evidence for the manifestations of Mendelian diseases.

Scientific Reports

Šimčíková, Daniela D; Heneberg, Petr P

Publication Date: 2019-12-09

Variant appearance in text: RET: G810A

PubMed Link: 31819097

Variant Present in the following documents:

• 41598_2019_54976_MOESM2_ESM.xlsx, sheet 8

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Structural basis of resistance of mutant RET protein-tyrosine kinase to its inhibitors nintedanib and vandetanib.

The Journal Of Biological Chemistry

Terzyan, Simon S SS; Shen, Tao T; Liu, Xuan X; Huang, Qingling Q; Teng, Peng P; Zhou, Mi M; Hilberg, Frank F; Cai, Jianfeng J; Mooers, Blaine H M BHM; Wu, Jie J

Publication Date: 2019-07-05

Variant appearance in text: RET: G810A

PubMed Link: 31118272

Variant Present in the following documents:

• Main text

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Comprehensive genomic and immunological characterization of Chinese non-small cell lung cancer patients.

Nature Communications

Zhang, Xu-Chao XC; Wang, Jun J; Shao, Guo-Guang GG; Wang, Qun Q; Qu, Xiaotao X; Wang, Bo B; Moy, Christopher C; Fan, Yue Y; Albertyn, Zayed Z; Huang, Xiayu X; Zhang, Jingyu J; Qiu, Yang Y; Platero, Suso S; Lorenzi, Matthew V MV; Zudaire, Enrique E; Yang, Jennifer J; Cheng, Ying Y; Xu, Lin L; Wu, Yi-Long YL

Publication Date: 2019-04-16

Variant appearance in text: RET: G810A

PubMed Link: 30992440

Variant Present in the following documents:

• 41467_2019_9762_MOESM13_ESM.xlsx, sheet 1

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Drug resistance profiles of mutations in the RET kinase domain.

British Journal Of Pharmacology

Liu, Xuan X; Shen, Tao T; Mooers, Blaine H M BHM; Hilberg, Frank F; Wu, Jie J

Publication Date: 2018-09

Variant appearance in text: RET: G810A

PubMed Link: 29908090

Variant Present in the following documents:

• Main text

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Targeting RET-driven cancers: lessons from evolving preclinical and clinical landscapes.

Nature Reviews. Clinical Oncology

Drilon, Alexander A; Hu, Zishuo I ZI; Lai, Gillianne G Y GGY; Tan, Daniel S W DSW

Publication Date: 2018-03

Variant appearance in text: RET: G810A

PubMed Link: 29134959

Variant Present in the following documents:

• Main text

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The molecular basis for RET tyrosine-kinase inhibitors in thyroid cancer.

Best Practice & Research. Clinical Endocrinology & Metabolism

De Falco, Valentina V; Carlomagno, Francesca F; Li, Hong-Yu HY; Santoro, Massimo M

Publication Date: 2017-06

Variant appearance in text: RET: G810A

PubMed Link: 28911727

Variant Present in the following documents:

• Main text

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Resistance to RET-Inhibition in RET-Rearranged NSCLC Is Mediated By Reactivation of RAS/MAPK Signaling.

Molecular Cancer Therapeutics

Nelson-Taylor, Sarah K SK; Le, Anh T AT; Yoo, Minjae M; Schubert, Laura L; Mishall, Katie M KM; Doak, Andrea A; Varella-Garcia, Marileila M; Tan, Aik-Choon AC; Doebele, Robert C RC

Publication Date: 2017-08

Variant appearance in text: RET: G810A

PubMed Link: 28500237

Variant Present in the following documents:

• Main text

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Preclinical Modeling of KIF5B-RET Fusion Lung Adenocarcinoma.

Molecular Cancer Therapeutics

Huang, Qingling Q; Schneeberger, Valentina E VE; Luetteke, Noreen N; Jin, Chengliu C; Afzal, Roha R; Budzevich, Mikalai M MM; Makanji, Rikesh J RJ; Martinez, Gary V GV; Shen, Tao T; Zhao, Lichao L; Fung, Kar-Ming KM; Haura, Eric B EB; Coppola, Domenico D; Wu, Jie J

Publication Date: 2016-10

Variant appearance in text: RET: G810A

PubMed Link: 27496134

Variant Present in the following documents:

• Main text

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