Publications:

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Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis.

Cancer Research

Tabata, Junya J; Nakaoku, Takashi T; Araki, Mitsugu M; Yoshino, Ryunosuke R; Kohsaka, Shinji S; Otsuka, Ayaka A; Ikegami, Masachika M; Ui, Ayako A; Kanno, Shin-Ichiro SI; Miyoshi, Keiko K; Matsumoto, Shigeyuki S; Sagae, Yukari Y; Yasui, Akira A; Sekijima, Masakazu M; Mano, Hiroyuki H; Okuno, Yasushi Y; Okamoto, Aikou A; Kohno, Takashi T

Publication Date: 2022-10-17

Variant appearance in text: RET: S891L

PubMed Link: 36166639

Variant Present in the following documents:

• can-22-0834_supplementary_figure_s5_suppsf5.pdf

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An integrative pan cancer analysis of RET aberrations and their potential clinical implications.

Scientific Reports

Zhou, Lei L; Li, Juanni J; Zhang, Xiaofang X; Xu, Zhijie Z; Yan, Yuanliang Y; Hu, Kuan K

Publication Date: 2022-08-17

Variant appearance in text: RET: S891L

PubMed Link: 35978072

Variant Present in the following documents:

• Main text
• 41598_2022_Article_17791.pdf

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Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.

Aging

Su, Xiaofan X; Jin, Haoxuan H; Wang, Jiaqian J; Lu, Huiping H; Gu, Tiantian T; Gao, Zhibo Z; Li, Manxiang M

Publication Date: 2022-05-25

Variant appearance in text: RET: 2672C>T; S891L

PubMed Link: 35613927

Variant Present in the following documents:

• aging-14-204101-s004.xlsx, sheet 1

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Identification of Immune-Related Gene Signatures in Lung Adenocarcinoma and Lung Squamous Cell Carcinoma.

Frontiers In Immunology

Li, Na N; Wang, Jiahong J; Zhan, Xianquan X

Publication Date: 2021

Variant appearance in text: RET: 2672C>T

PubMed Link: 34887858

Variant Present in the following documents:

• Table_4.xlsx, sheet 1

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Association between somatic RET mutations and clinical and genetic characteristics in patients with metastatic colorectal cancer.

Cancer Medicine

Yang, Yuan-Zhong YZ; Hu, Wan-Ming WM; Xia, Liang-Ping LP; He, Wen-Zhuo WZ

Publication Date: 2021-11-05

Variant appearance in text: RET: S891L

PubMed Link: 34741450

Variant Present in the following documents:

• Main text
• CAM4-10-8876.pdf

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Association between somatic RET mutations and clinical and genetic characteristics in patients with metastatic colorectal cancer.

Cancer Medicine

Yang, Yuan-Zhong YZ; Hu, Wan-Ming WM; Xia, Liang-Ping LP; He, Wen-Zhuo WZ

Publication Date: 2021-12

Variant appearance in text: RET: S891L

PubMed Link: 34741450

Variant Present in the following documents:

• Main text
• CAM4-10-8876.pdf

View BVdb publication page

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Comparative Analysis of Genetic Alterations, HPV-Status, and PD-L1 Expression in Neuroendocrine Carcinomas of the Cervix.

Cancers

Takayanagi, Daisuke D; Hirose, Sou S; Kuno, Ikumi I; Asami, Yuka Y; Murakami, Naoya N; Matsuda, Maiko M; Shimada, Yoko Y; Sunami, Kuniko K; Komatsu, Masaaki M; Hamamoto, Ryuji R; Kato, Mayumi Kobayashi MK; Matsumoto, Koji K; Kohno, Takashi T; Kato, Tomoyasu T; Shiraishi, Kouya K; Yoshida, Hiroshi H

Publication Date: 2021-03-10

Variant appearance in text: RET: S891L

PubMed Link: 33802174

Variant Present in the following documents:

• Main text
• cancers-13-01215.pdf

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Patient-derived xenografts and organoids model therapy response in prostate cancer.

Nature Communications

Karkampouna, Sofia S; La Manna, Federico F; Benjak, Andrej A; Kiener, Mirjam M; De Menna, Marta M; Zoni, Eugenio E; Grosjean, Joël J; Klima, Irena I; Garofoli, Andrea A; Bolis, Marco M; Vallerga, Arianna A; Theurillat, Jean-Philippe JP; De Filippo, Maria R MR; Genitsch, Vera V; Keller, David D; Booij, Tijmen H TH; Stirnimann, Christian U CU; Eng, Kenneth K; Sboner, Andrea A; Ng, Charlotte K Y CKY; Piscuoglio, Salvatore S; Gray, Peter C PC; Spahn, Martin M; Rubin, Mark A MA; Thalmann, George N GN; Kruithof-de Julio, Marianna M

Publication Date: 2021-02-18

Variant appearance in text: RET: Ser891Leu

PubMed Link: 33602919

Variant Present in the following documents:

• Main text
• 41467_2021_21300_MOESM1_ESM.pdf
• 41467_2021_Article_21300.pdf
• 41467_2021_21300_MOESM4_ESM.xlsx, sheet 1

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Diversity spectrum analysis identifies mutation-specific effects of cancer driver genes.

Communications Biology

Dong, Xiaobao X; Huang, Dandan D; Yi, Xianfu X; Zhang, Shijie S; Wang, Zhao Z; Yan, Bin B; Chung Sham, Pak P; Chen, Kexin K; Jun Li, Mulin M

Publication Date: 2020-01-07

Variant appearance in text: RET: 2672C>T; S891L

PubMed Link: 31925297

Variant Present in the following documents:

• 42003_2019_736_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Refinement of evolutionary medicine predictions based on clinical evidence for the manifestations of Mendelian diseases.

Scientific Reports

Šimčíková, Daniela D; Heneberg, Petr P

Publication Date: 2019-12-09

Variant appearance in text: RET: S891L

PubMed Link: 31819097

Variant Present in the following documents:

• 41598_2019_54976_MOESM2_ESM.xlsx, sheet 8

View BVdb publication page

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Targeted mutation detection in breast cancer using MammaSeq™.

Breast Cancer Research : Bcr

Smith, Nicholas G NG; Gyanchandani, Rekha R; Shah, Osama S OS; Gurda, Grzegorz T GT; Lucas, Peter C PC; Hartmaier, Ryan J RJ; Brufsky, Adam M AM; Puhalla, Shannon S; Bahreini, Amir A; Kota, Karthik K; Wald, Abigail I AI; Nikiforov, Yuri E YE; Nikiforova, Marina N MN; Oesterreich, Steffi S; Lee, Adrian V AV

Publication Date: 2019-02-08

Variant appearance in text: RET: S891L

PubMed Link: 30736836

Variant Present in the following documents:

• 13058_2019_1102_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

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Integrative omics analyses broaden treatment targets in human cancer.

Genome Medicine

Sengupta, Sohini S; Sun, Sam Q SQ; Huang, Kuan-Lin KL; Oh, Clara C; Bailey, Matthew H MH; Varghese, Rajees R; Wyczalkowski, Matthew A MA; Ning, Jie J; Tripathi, Piyush P; McMichael, Joshua F JF; Johnson, Kimberly J KJ; Kandoth, Cyriac C; Welch, John J; Ma, Cynthia C; Wendl, Michael C MC; Payne, Samuel H SH; Fenyö, David D; Townsend, Reid R RR; Dipersio, John F JF; Chen, Feng F; Ding, Li L

Publication Date: 2018-07-27

Variant appearance in text: RET: S891L

PubMed Link: 30053901

Variant Present in the following documents:

• 13073_2018_564_MOESM2_ESM.xlsx, sheet 17
• 13073_2018_564_MOESM2_ESM.xlsx, sheet 2

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Genetic and Genomic Characterization of 462 Melanoma Patient-Derived Xenografts, Tumor Biopsies, and Cell Lines.

Cell Reports

Garman, Bradley B; Anastopoulos, Ioannis N IN; Krepler, Clemens C; Brafford, Patricia P; Sproesser, Katrin K; Jiang, Yuchao Y; Wubbenhorst, Bradley B; Amaravadi, Ravi R; Bennett, Joseph J; Beqiri, Marilda M; Elder, David D; Flaherty, Keith T KT; Frederick, Dennie T DT; Gangadhar, Tara C TC; Guarino, Michael M; Hoon, David D; Karakousis, Giorgos G; Liu, Qin Q; Mitra, Nandita N; Petrelli, Nicholas J NJ; Schuchter, Lynn L; Shannan, Batool B; Shields, Carol L CL; Wargo, Jennifer J; Wenz, Brandon B; Wilson, Melissa A MA; Xiao, Min M; Xu, Wei W; Xu, Xaiowei X; Yin, Xiangfan X; Zhang, Nancy R NR; Davies, Michael A MA; Herlyn, Meenhard M; Nathanson, Katherine L KL

Publication Date: 2017-11-14

Variant appearance in text: RET: S891L

PubMed Link: 29141224

Variant Present in the following documents:

• Main text

View BVdb publication page

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Detecting protein variants by mass spectrometry: a comprehensive study in cancer cell-lines.

Genome Medicine

Alfaro, Javier A JA; Ignatchenko, Alexandr A; Ignatchenko, Vladimir V; Sinha, Ankit A; Boutros, Paul C PC; Kislinger, Thomas T

Publication Date: 2017-07-18

Variant appearance in text: RET: S891L

PubMed Link: 28716134

Variant Present in the following documents:

• 13073_2017_454_MOESM7_ESM.xlsx, sheet 1
• 13073_2017_454_MOESM6_ESM.xlsx, sheet 1

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The somatic POLE P286R mutation defines a unique subclass of colorectal cancer featuring hypermutation, representing a potential genomic biomarker for immunotherapy.

Oncotarget

Ahn, Sung-Min SM; Ansari, Adnan Ahmad AA; Kim, Jihun J; Kim, Deokhoon D; Chun, Sung-Min SM; Kim, Jiyun J; Kim, Tae Won TW; Park, Inja I; Yu, Chang-Sik CS; Jang, Se Jin SJ

Publication Date: 2016-10-18

Variant appearance in text: RET: S891L

PubMed Link: 27612425

Variant Present in the following documents:

• oncotarget-07-68638-s008.xlsx, sheet 1

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Age-related mutations associated with clonal hematopoietic expansion and malignancies.

Nature Medicine

Xie, Mingchao M; Lu, Charles C; Wang, Jiayin J; McLellan, Michael D MD; Johnson, Kimberly J KJ; Wendl, Michael C MC; McMichael, Joshua F JF; Schmidt, Heather K HK; Yellapantula, Venkata V; Miller, Christopher A CA; Ozenberger, Bradley A BA; Welch, John S JS; Link, Daniel C DC; Walter, Matthew J MJ; Mardis, Elaine R ER; Dipersio, John F JF; Chen, Feng F; Wilson, Richard K RK; Ley, Timothy J TJ; Ding, Li L

Publication Date: 2014-12

Variant appearance in text: RET: S891L

PubMed Link: 25326804

Variant Present in the following documents:

• NIHMS630249-supplement-6.xlsx, sheet 1
• NIHMS630249-supplement-5.xlsx, sheet 1

View BVdb publication page

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