Effect of PTPN22, FAS/FASL, IL2RA and CTLA4 genetic polymorphisms on the risk of developing alopecia areata: A systematic review of the literature and meta-analysis.
Plos One
Gil-Quiñones, S R SR; Sepúlveda-Pachón, I T IT; Sánchez Vanegas, G G; Gutierrez-Castañeda, L D LD
Effect of PTPN22, FAS/FASL, IL2RA and CTLA4 genetic polymorphisms on the risk of developing alopecia areata: A systematic review of the literature and meta-analysis.
Plos One
Gil-Quiñones, S R SR; Sepúlveda-Pachón, I T IT; Sánchez Vanegas, G G; Gutierrez-Castañeda, L D LD
Functional genomics atlas of synovial fibroblasts defining rheumatoid arthritis heritability.
Genome Biology
Ge, Xiangyu X; Frank-Bertoncelj, Mojca M; Klein, Kerstin K; McGovern, Amanda A; Kuret, Tadeja T; Houtman, Miranda M; Burja, Blaž B; Micheroli, Raphael R; Shi, Chenfu C; Marks, Miriam M; Filer, Andrew A; Buckley, Christopher D CD; Orozco, Gisela G; Distler, Oliver O; Morris, Andrew P AP; Martin, Paul P; Eyre, Stephen S; Ospelt, Caroline C
Type 1 diabetes: genes associated with disease development.
Central-European Journal Of Immunology
Klak, Marta M; Gomółka, Magdalena M; Kowalska, Patrycja P; Cichoń, Justyna J; Ambrożkiewicz, Filip F; Serwańska-Świętek, Marta M; Berman, Andrzej A; Wszoła, Michał M
Combined genetic analysis of juvenile idiopathic arthritis clinical subtypes identifies novel risk loci, target genes and key regulatory mechanisms.
Annals Of The Rheumatic Diseases
López-Isac, Elena E; Smith, Samantha L SL; Marion, Miranda C MC; Wood, Abigail A; Sudman, Marc M; Yarwood, Annie A; Shi, Chenfu C; Gaddi, Vasanthi Priyadarshini VP; Martin, Paul P; Prahalad, Sampath S; Eyre, Stephen S; Orozco, Gisela G; Morris, Andrew P AP; Langefeld, Carl D CD; Thompson, Susan D SD; Thomson, Wendy W; Bowes, John J
Combined genetic analysis of juvenile idiopathic arthritis clinical subtypes identifies novel risk loci, target genes and key regulatory mechanisms.
Annals Of The Rheumatic Diseases
López-Isac, Elena E; Smith, Samantha L SL; Marion, Miranda C MC; Wood, Abigail A; Sudman, Marc M; Yarwood, Annie A; Shi, Chenfu C; Gaddi, Vasanthi Priyadarshini VP; Martin, Paul P; Prahalad, Sampath S; Eyre, Stephen S; Orozco, Gisela G; Morris, Andrew P AP; Langefeld, Carl D CD; Thompson, Susan D SD; Thomson, Wendy W; Bowes, John J
Genetic Association Study of IL2RA, IFIH1, and CTLA-4 Polymorphisms With Autoimmune Thyroid Diseases and Type 1 Diabetes.
Frontiers In Pediatrics
Borysewicz-Sańczyk, Hanna H; Sawicka, Beata B; Wawrusiewicz-Kurylonek, Natalia N; Głowińska-Olszewska, Barbara B; Kadłubiska, Anna A; Gościk, Joanna J; Szadkowska, Agnieszka A; Łosiewicz, Aleksandra A; Młynarski, Wojciech W; Kretowski, Adam A; Bossowski, Artur A
Association analysis in a Latin American population revealed ethnic differences in rheumatoid arthritis-associated SNPs in Caucasian and Asian populations.
Scientific Reports
Castro-Santos, P P; Verdugo, R A RA; Alonso-Arias, R R; Gutiérrez, M A MA; Suazo, J J; Aguillón, J C JC; Olloquequi, J J; Pinochet, C C; Lucia, A A; Quiñones, L A LA; Díaz-Peña, R R
Genetic Variants in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Bayesian Approach and Systematic Review.
Journal Of Clinical Medicine
Lee, Kwang Seob KS; Kronbichler, Andreas A; Pereira Vasconcelos, Daniel Fernando DF; Pereira da Silva, Felipe Rodolfo FR; Ko, Younhee Y; Oh, Yeon Su YS; Eisenhut, Michael M; Merkel, Peter A PA; Jayne, David D; Amos, Christopher I CI; Siminovitch, Katherine A KA; Rahmattulla, Chinar C; Lee, Keum Hwa KH; Shin, Jae Il JI
Polymorphisms in the TGFB1 and IL2RA genes are associated with clinical forms of leprosy in Brazilian population.
Memorias Do Instituto Oswaldo Cruz
Camargo, Rodrigo Mendes de RM; Silva, Weber Laurentino da WLD; Medeiros, Priscila P; Belone, Andrea de Faria Fernandes AFF; Latini, Ana Carla Pereira ACP
Genetic influences on susceptibility to rheumatoid arthritis in African-Americans.
Human Molecular Genetics
Laufer, Vincent A VA; Tiwari, Hemant K HK; Reynolds, Richard J RJ; Danila, Maria I MI; Wang, Jelai J; Edberg, Jeffrey C JC; Kimberly, Robert P RP; Kottyan, Leah C LC; Harley, John B JB; Mikuls, Ted R TR; Gregersen, Peter K PK; Absher, Devin M DM; Langefeld, Carl D CD; Arnett, Donna K DK; Bridges, S Louis SL
Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes.
Nature Genetics
Westra, Harm-Jan HJ; Martínez-Bonet, Marta M; Onengut-Gumuscu, Suna S; Lee, Annette A; Luo, Yang Y; Teslovich, Nikola N; Worthington, Jane J; Martin, Javier J; Huizinga, Tom T; Klareskog, Lars L; Rantapaa-Dahlqvist, Solbritt S; Chen, Wei-Min WM; Quinlan, Aaron A; Todd, John A JA; Eyre, Steve S; Nigrovic, Peter A PA; Gregersen, Peter K PK; Rich, Stephen S SS; Raychaudhuri, Soumya S
A type 1 diabetes genetic risk score can discriminate monogenic autoimmunity with diabetes from early-onset clustering of polygenic autoimmunity with diabetes.
Diabetologia
Johnson, Matthew B MB; Patel, Kashyap A KA; De Franco, Elisa E; Houghton, Jayne A L JAL; McDonald, Timothy J TJ; Ellard, Sian S; Flanagan, Sarah E SE; Hattersley, Andrew T AT
Two separate effects contribute to regulatory T cell defect in systemic lupus erythematosus patients and their unaffected relatives.
Clinical And Experimental Immunology
Costa, N N; Marques, O O; Godinho, S I SI; Carvalho, C C; Leal, B B; Figueiredo, A M AM; Vasconcelos, C C; Marinho, A A; Moraes-Fontes, M F MF; Gomes da Costa, A A; Ponte, C C; Campanilho-Marques, R R; Cóias, T T; Martins, A R AR; Viana, J F JF; Lima, M M; Martins, B B; Fesel, C C
The single nucleotide variant rs12722489 determines differential estrogen receptor binding and enhancer properties of an IL2RA intronic region.
Plos One
Afanasyeva, Marina A MA; Putlyaeva, Lidia V LV; Demin, Denis E DE; Kulakovskiy, Ivan V IV; Vorontsov, Ilya E IE; Fridman, Marina V MV; Makeev, Vsevolod J VJ; Kuprash, Dmitry V DV; Schwartz, Anton M AM
Dissecting the Genetic Susceptibility to Graves' Disease in a Cohort of Patients of Italian Origin.
Frontiers In Endocrinology
Lombardi, Angela A; Menconi, Francesca F; Greenberg, David D; Concepcion, Erlinda E; Leo, Marenza M; Rocchi, Roberto R; Marinó, Michele M; Keddache, Mehdi M; Tomer, Yaron Y
Identification of rheumatoid arthritis biomarkers based on single nucleotide polymorphisms and haplotype blocks: A systematic review and meta-analysis.
Journal Of Advanced Research
Saad, Mohamed N MN; Mabrouk, Mai S MS; Eldeib, Ayman M AM; Shaker, Olfat G OG
Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.
Nature Medicine
Li, Yun R YR; Li, Jin J; Zhao, Sihai D SD; Bradfield, Jonathan P JP; Mentch, Frank D FD; Maggadottir, S Melkorka SM; Hou, Cuiping C; Abrams, Debra J DJ; Chang, Diana D; Gao, Feng F; Guo, Yiran Y; Wei, Zhi Z; Connolly, John J JJ; Cardinale, Christopher J CJ; Bakay, Marina M; Glessner, Joseph T JT; Li, Dong D; Kao, Charlly C; Thomas, Kelly A KA; Qiu, Haijun H; Chiavacci, Rosetta M RM; Kim, Cecilia E CE; Wang, Fengxiang F; Snyder, James J; Richie, Marylyn D MD; Flatø, Berit B; Førre, Øystein Ø; Denson, Lee A LA; Thompson, Susan D SD; Becker, Mara L ML; Guthery, Stephen L SL; Latiano, Anna A; Perez, Elena E; Resnick, Elena E; Russell, Richard K RK; Wilson, David C DC; Silverberg, Mark S MS; Annese, Vito V; Lie, Benedicte A BA; Punaro, Marilynn M; Dubinsky, Marla C MC; Monos, Dimitri S DS; Strisciuglio, Caterina C; Staiano, Annamaria A; Miele, Erasmo E; Kugathasan, Subra S; Ellis, Justine A JA; Munro, Jane E JE; Sullivan, Kathleen E KE; Wise, Carol A CA; Chapel, Helen H; Cunningham-Rundles, Charlotte C; Grant, Struan F A SF; Orange, Jordan S JS; Sleiman, Patrick M A PM; Behrens, Edward M EM; Griffiths, Anne M AM; Satsangi, Jack J; Finkel, Terri H TH; Keinan, Alon A; Prak, Eline T Luning ET; Polychronakos, Constantin C; Baldassano, Robert N RN; Li, Hongzhe H; Keating, Brendan J BJ; Hakonarson, Hakon H
Genetic variants in interleukin genes are associated with breast cancer risk and survival in a genetically admixed population: the Breast Cancer Health Disparities Study.
Carcinogenesis
Slattery, Martha L ML; Herrick, Jennifer S JS; Torres-Mejia, Gabriella G; John, Esther M EM; Giuliano, Anna R AR; Hines, Lisa M LM; Stern, Mariana C MC; Baumgartner, Kathy B KB; Presson, Angela P AP; Wolff, Roger K RK
Genetics of rheumatoid arthritis contributes to biology and drug discovery.
Nature
Okada, Yukinori Y; Wu, Di D; Trynka, Gosia G; Raj, Towfique T; Terao, Chikashi C; Ikari, Katsunori K; Kochi, Yuta Y; Ohmura, Koichiro K; Suzuki, Akari A; Yoshida, Shinji S; Graham, Robert R RR; Manoharan, Arun A; Ortmann, Ward W; Bhangale, Tushar T; Denny, Joshua C JC; Carroll, Robert J RJ; Eyler, Anne E AE; Greenberg, Jeffrey D JD; Kremer, Joel M JM; Pappas, Dimitrios A DA; Jiang, Lei L; Yin, Jian J; Ye, Lingying L; Su, Ding-Feng DF; Yang, Jian J; Xie, Gang G; Keystone, Ed E; Westra, Harm-Jan HJ; Esko, Tõnu T; Metspalu, Andres A; Zhou, Xuezhong X; Gupta, Namrata N; Mirel, Daniel D; Stahl, Eli A EA; Diogo, Dorothée D; Cui, Jing J; Liao, Katherine K; Guo, Michael H MH; Myouzen, Keiko K; Kawaguchi, Takahisa T; Coenen, Marieke J H MJ; van Riel, Piet L C M PL; van de Laar, Mart A F J MA; Guchelaar, Henk-Jan HJ; Huizinga, Tom W J TW; Dieudé, Philippe P; Mariette, Xavier X; Bridges, S Louis SL; Zhernakova, Alexandra A; Toes, Rene E M RE; Tak, Paul P PP; Miceli-Richard, Corinne C; Bang, So-Young SY; Lee, Hye-Soon HS; Martin, Javier J; Gonzalez-Gay, Miguel A MA; Rodriguez-Rodriguez, Luis L; Rantapää-Dahlqvist, Solbritt S; Arlestig, Lisbeth L; Choi, Hyon K HK; Kamatani, Yoichiro Y; Galan, Pilar P; Lathrop, Mark M; , ; , ; Eyre, Steve S; Bowes, John J; Barton, Anne A; de Vries, Niek N; Moreland, Larry W LW; Criswell, Lindsey A LA; Karlson, Elizabeth W EW; Taniguchi, Atsuo A; Yamada, Ryo R; Kubo, Michiaki M; Liu, Jun S JS; Bae, Sang-Cheol SC; Worthington, Jane J; Padyukov, Leonid L; Klareskog, Lars L; Gregersen, Peter K PK; Raychaudhuri, Soumya S; Stranger, Barbara E BE; De Jager, Philip L PL; Franke, Lude L; Visscher, Peter M PM; Brown, Matthew A MA; Yamanaka, Hisashi H; Mimori, Tsuneyo T; Takahashi, Atsushi A; Xu, Huji H; Behrens, Timothy W TW; Siminovitch, Katherine A KA; Momohara, Shigeki S; Matsuda, Fumihiko F; Yamamoto, Kazuhiko K; Plenge, Robert M RM
Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits.
Genome Research
Corradin, Olivia O; Saiakhova, Alina A; Akhtar-Zaidi, Batool B; Myeroff, Lois L; Willis, Joseph J; Cowper-Sal lari, Richard R; Lupien, Mathieu M; Markowitz, Sanford S; Scacheri, Peter C PC
Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking.
Plos Genetics
Scott, Ian C IC; Seegobin, Seth D SD; Steer, Sophia S; Tan, Rachael R; Forabosco, Paola P; Hinks, Anne A; Eyre, Stephen S; Morgan, Ann W AW; Wilson, Anthony G AG; Hocking, Lynne J LJ; Wordsworth, Paul P; Barton, Anne A; Worthington, Jane J; Cope, Andrew P AP; Lewis, Cathryn M CM
Identification of the tyrosine-protein phosphatase non-receptor type 2 as a rheumatoid arthritis susceptibility locus in europeans.
Plos One
Cobb, Joanna E JE; Plant, Darren D; Flynn, Edward E; Tadjeddine, Meriem M; Dieudé, Philippe P; Cornélis, François F; Ärlestig, Lisbeth L; Dahlqvist, Solbritt Rantapää SR; Goulielmos, George G; Boumpas, Dimitrios T DT; Sidiropoulos, Prodromos P; Krintel, Sophine B SB; Ørnbjerg, Lykke M LM; Hetland, Merete L ML; Klareskog, Lars L; Haeupl, Thomas T; Filer, Andrew A; Buckley, Christopher D CD; Raza, Karim K; Witte, Torsten T; Schmidt, Reinhold E RE; FitzGerald, Oliver O; Veale, Douglas D; Eyre, Stephen S; Worthington, Jane J
Shared ancestral susceptibility to colorectal cancer and other nutrition related diseases.
Bmc Medical Genetics
Huhn, Stefanie S; Bevier, Melanie M; Rudolph, Anja A; Pardini, Barbara B; Naccarati, Alessio A; Hein, Rebecca R; Hoffmeister, Michael M; Vodickova, Ludmila L; Novotny, Jan J; Brenner, Hermann H; Chang-Claude, Jenny J; Hemminki, Kari K; Vodicka, Pavel P; Försti, Asta A
Meta-analysis of genetic polymorphisms in granulomatosis with polyangiitis (Wegener's) reveals shared susceptibility loci with rheumatoid arthritis.
Arthritis And Rheumatism
Chung, Sharon A SA; Xie, Gang G; Roshandel, Delnaz D; Sherva, Richard R; Edberg, Jeffrey C JC; Kravitz, Megan M; Dellaripa, Paul F PF; Hoffman, Gary S GS; Mahr, Alfred D AD; Seo, Philip P; Specks, Ulrich U; Spiera, Robert F RF; St Clair, E William EW; Stone, John H JH; Plenge, Robert M RM; Siminovitch, Katherine A KA; Merkel, Peter A PA; Monach, Paul A PA
Compensatory T-cell regulation in unaffected relatives of SLE patients, and opposite IL-2/CD25-mediated effects suggested by coreferentiality modeling.
Plos One
Fesel, Constantin C; Barreto, Marta M; Ferreira, Ricardo C RC; Costa, Nuno N; Venda, Lara L LL; Pereira, Clara C; Carvalho, Claudia C; Morães-Fontes, Maria Francisca MF; Ferreira, Carlos M CM; Vasconcelos, Carlos C; Viana, João F JF; Santos, Eugenia E; Martins, Berta B; Demengeot, Jocelyne J; Vicente, Astrid M AM
Comprehensive assessment of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort.
Annals Of The Rheumatic Diseases
Bowes, John J; Ho, Pauline P; Flynn, Edward E; Ali, Faisal F; Marzo-Ortega, Helena H; Coates, Laura C LC; Warren, Richard B RB; McManus, Ross R; Ryan, Anthony W AW; Kane, David D; Korendowych, Eleanor E; McHugh, Neil N; FitzGerald, Oliver O; Packham, Jonathon J; Morgan, Ann W AW; Bruce, Ian N IN; Barton, Anne A
Investigation of rheumatoid arthritis susceptibility loci in juvenile idiopathic arthritis confirms high degree of overlap.
Annals Of The Rheumatic Diseases
Hinks, Anne A; Cobb, Joanna J; Sudman, Marc M; Eyre, Stephen S; Martin, Paul P; Flynn, Edward E; Packham, Jonathon J; , ; , ; , ; Barton, Anne A; Worthington, Jane J; Langefeld, Carl D CD; Glass, David N DN; Thompson, Susan D SD; Thomson, Wendy W