Publications:

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Activation of PTEN/P13K/AKT Signaling Pathway by miRNA-124-3p-Loaded Nanoparticles to Regulate Oxidative Stress Attenuates Cardiomyocyte Regulation and Myocardial Injury.

Oxidative Medicine And Cellular Longevity

Cheng, Yuan Y; He, Qing Q; Li, Na N; Luo, Mengdi M

Publication Date: 2022

Variant appearance in text: PTEN: R14A

PubMed Link: 36267811

Variant Present in the following documents:

• OMCL2022-8428596.pdf

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miR-27a is a master regulator of metabolic reprogramming and chemoresistance in colorectal cancer.

British Journal Of Cancer

Barisciano, Giovannina G; Colangelo, Tommaso T; Rosato, Valeria V; Muccillo, Livio L; Taddei, Maria Letizia ML; Ippolito, Luigi L; Chiarugi, Paola P; Galgani, Mario M; Bruzzaniti, Sara S; Matarese, Giuseppe G; Fassan, Matteo M; Agostini, Marco M; Bergamo, Francesca F; Pucciarelli, Salvatore S; Carbone, Annalucia A; Mazzoccoli, Gianluigi G; Colantuoni, Vittorio V; Bianchi, Fabrizio F; Sabatino, Lina L

Publication Date: 2020-04

Variant appearance in text: PTEN: R14A

PubMed Link: 32132656

Variant Present in the following documents:

• 41416_2020_773_MOESM1_ESM.pdf

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The Impact of Genetic Variants on PTEN Molecular Functions and Cellular Phenotypes.

Cold Spring Harbor Perspectives In Medicine

Hasle, Nicholas N; Matreyek, Kenneth A KA; Fowler, Douglas M DM

Publication Date: 2019-11-01

Variant appearance in text: PTEN: R14A

PubMed Link: 31451538

Variant Present in the following documents:

• Main text

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A functional dissection of PTEN N-terminus: implications in PTEN subcellular targeting and tumor suppressor activity.

Plos One

Gil, Anabel A; Rodríguez-Escudero, Isabel I; Stumpf, Miriam M; Molina, María M; Cid, Víctor J VJ; Pulido, Rafael R

Publication Date: 2015

Variant appearance in text: PTEN: R14A

PubMed Link: 25875300

Variant Present in the following documents:

• Main text

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Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease.

Neurobiology Of Disease

Chen, Chun-Hau CH; Li, Wenzong W; Sultana, Rukhsana R; You, Mi-Hyeon MH; Kondo, Asami A; Shahpasand, Koorosh K; Kim, Byeong Mo BM; Luo, Man-Li ML; Nechama, Morris M; Lin, Yu-Min YM; Yao, Yandan Y; Lee, Tae Ho TH; Zhou, Xiao Zhen XZ; Swomley, Aaron M AM; Butterfield, D Allan DA; Zhang, Yan Y; Lu, Kun Ping KP

Publication Date: 2015-04

Variant appearance in text: PTEN: R14A

PubMed Link: 25576397

Variant Present in the following documents:

• Main text

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Engineering ePTEN, an enhanced PTEN with increased tumor suppressor activities.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Nguyen, Hoai-Nghia HN; Yang, Jr-Ming JM; Afkari, Yashar Y; Park, Ben Ho BH; Sesaki, Hiromi H; Devreotes, Peter N PN; Iijima, Miho M

Publication Date: 2014-07-01

Variant appearance in text: PTEN: R14A

PubMed Link: 24979808

Variant Present in the following documents:

• Main text

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Phosphorylation-mediated PTEN conformational closure and deactivation revealed with protein semisynthesis.

Elife

Bolduc, David D; Rahdar, Meghdad M; Tu-Sekine, Becky B; Sivakumaren, Sindhu Carmen SC; Raben, Daniel D; Amzel, L Mario LM; Devreotes, Peter P; Gabelli, Sandra B SB; Cole, Philip P

Publication Date: 2013-07-09

Variant appearance in text: PTEN: R14A

PubMed Link: 23853711

Variant Present in the following documents:

• Main text
• elife00691.pdf

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Mechanistic analysis of a DNA damage-induced, PTEN-dependent size checkpoint in human cells.

Molecular And Cellular Biology

Kim, Jung-Sik JS; Xu, Xuehua X; Li, Huifang H; Solomon, David D; Lane, William S WS; Jin, Tian T; Waldman, Todd T

Publication Date: 2011-07

Variant appearance in text: PTEN: R14A

PubMed Link: 21536651

Variant Present in the following documents:

• Main text

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A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Rahdar, Meghdad M; Inoue, Takanari T; Meyer, Tobias T; Zhang, Jin J; Vazquez, Francisca F; Devreotes, Peter N PN

Publication Date: 2009-01-13

Variant appearance in text: PTEN: R14A

PubMed Link: 19114656

Variant Present in the following documents:

• Main text

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Nuclear localization of PTEN by a Ran-dependent mechanism enhances apoptosis: Involvement of an N-terminal nuclear localization domain and multiple nuclear exclusion motifs.

Molecular Biology Of The Cell

Gil, Anabel A; Andrés-Pons, Amparo A; Fernández, Elena E; Valiente, Miguel M; Torres, Josema J; Cervera, Javier J; Pulido, Rafael R

Publication Date: 2006-09

Variant appearance in text: PTEN: R14A

PubMed Link: 16807353

Variant Present in the following documents:

• Main text

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Membrane-binding and activation mechanism of PTEN.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Das, Sudipto S; Dixon, Jack E JE; Cho, Wonhwa W

Publication Date: 2003-06-24

Variant appearance in text: PTEN: R14A

PubMed Link: 12808147

Variant Present in the following documents:

• Main text

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