Publications:

A computational method for prioritizing targeted therapies in precision oncology: performance analysis in the SHIVA01 trial.

Npj Precision Oncology

Petak, Istvan I; Kamal, Maud M; Dirner, Anna A; Bieche, Ivan I; Doczi, Robert R; Mariani, Odette O; Filotas, Peter P; Salomon, Anne A; Vodicska, Barbara B; Servois, Vincent V; Varkondi, Edit E; Gentien, David D; Tihanyi, Dora D; Tresca, Patricia P; Lakatos, Dora D; Servant, Nicolas N; Deri, Julia J; du Rusquec, Pauline P; Hegedus, Csilla C; Bello Roufai, Diana D; Schwab, Richard R; Dupain, Celia C; Valyi-Nagy, Istvan T IT; Le Tourneau, Christophe C

Publication Date: 2021-06-23

Variant appearance in text: PTEN: L23*

PubMed Link: 34162980

Variant Present in the following documents:

• 41698_2021_191_MOESM7_ESM.xlsx, sheet 1

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Exceptional Response to AKT Inhibition in Patients With Breast Cancer and Germline PTEN Mutations.

Jco Precision Oncology

Kingston, Belinda B; Bailleux, Caroline C; Delaloge, Suzette S; Schiavon, Gaia G; Scott, Veronique V; Lacroix-Triki, Magali M; Carr, T Hedley TH; Kozarewa, Iwanka I; Gevensleben, Heidrun H; Kemp, Zoe Z; Pearson, Alex A; Turner, Nicholas N; André, Fabrice F

Publication Date: 2019

Variant appearance in text: PTEN: L23X

PubMed Link: 32923864

Variant Present in the following documents:

• Main text
• PO.19.00130.pdf

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mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis.

Cell Reports

Triki, Mouna M; Rinaldi, Gianmarco G; Planque, Melanie M; Broekaert, Dorien D; Winkelkotte, Alina M AM; Maier, Carina R CR; Janaki Raman, Sudha S; Vandekeere, Anke A; Van Elsen, Joke J; Orth, Martin F MF; Grünewald, Thomas G P TGP; Schulze, Almut A; Fendt, Sarah-Maria SM

Publication Date: 2020-06-23

Variant appearance in text: PTEN: L23*

PubMed Link: 32579932

Variant Present in the following documents:

• mmc5.xlsx, sheet 3

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Hidden association of Cowden syndrome, PTEN mutation and meningioma frequency.

Oncoscience

Yakubov, Eduard E; Ghoochani, Ali A; Buslei, Rolf R; Buchfelder, Michael M; Eyüpoglu, Ilker Y IY; Savaskan, Nicolai N

Publication Date: 2016

Variant appearance in text: PTEN: 68T>A

PubMed Link: 27489861

Variant Present in the following documents:

• oncoscience-03-149-s001.pdf

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Germline PTEN mutations are rare and highly penetrant.

Hereditary Cancer In Clinical Practice

Rustad, Cecilie F CF; Bjørnslett, Merete M; Heimdal, Ketil R KR; Mæhle, Lovise L; Apold, Jaran J; Møller, Pål P

Publication Date: 2006-12-15

Variant appearance in text: PTEN: 68T>A

PubMed Link: 20223021

Variant Present in the following documents:

• Main text
• 1897-4287-4-4-177.pdf

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