Publications:

Furin extracellularly cleaves secreted PTENα/β to generate C-terminal fragment with a tumor-suppressive role.

Cell Death & Disease

Zhang, Cheng C; Ma, Hong-Ming HM; Dong, Shuang-Shu SS; Zhang, Na N; He, Ping P; Ge, Meng-Kai MK; Xia, Li L; Yu, Jian-Xiu JX; Xia, Qiang Q; Chen, Guo-Qiang GQ; Shen, Shao-Ming SM

Publication Date: 2022-06-06

Variant appearance in text: PTEN: R47A

PubMed Link: 35668069

Variant Present in the following documents:

• Main text
• 41419_2022_Article_4988.pdf

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Single-molecule imaging of PI(4,5)P2 and PTEN in vitro reveals a positive feedback mechanism for PTEN membrane binding.

Communications Biology

Yoshioka, Daisuke D; Fukushima, Seiya S; Koteishi, Hiroyasu H; Okuno, Daichi D; Ide, Toru T; Matsuoka, Satomi S; Ueda, Masahiro M

Publication Date: 2020-02-28

Variant appearance in text: PTEN: R47A

PubMed Link: 32111929

Variant Present in the following documents:

• Main text
• 42003_2020_818_MOESM3_ESM.xlsx, sheet 5
• 42003_2020_818_MOESM7_ESM.xlsx, sheet 1
• 42003_2020_818_MOESM1_ESM.pdf
• 42003_2020_Article_818.pdf

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PTEN stabilizes TOP2A and regulates the DNA decatenation.

Scientific Reports

Kang, Xi X; Song, Chang C; Du, Xiao X; Zhang, Cong C; Liu, Yu Y; Liang, Ling L; He, Jinxue J; Lamb, Kristy K; Shen, Wen H WH; Yin, Yuxin Y

Publication Date: 2015-12-10

Variant appearance in text: PTEN: R47A

PubMed Link: 26657567

Variant Present in the following documents:

• Main text
• srep17873.pdf

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Phospholipid-binding sites of phosphatase and tensin homolog (PTEN): exploring the mechanism of phosphatidylinositol 4,5-bisphosphate activation.

The Journal Of Biological Chemistry

Wei, Yang Y; Stec, Boguslaw B; Redfield, Alfred G AG; Weerapana, Eranthie E; Roberts, Mary F MF

Publication Date: 2015-01-16

Variant appearance in text: PTEN: R47A

PubMed Link: 25429968

Variant Present in the following documents:

• Main text

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