PTEN c.141G>T ;(p.R47S)

Variant ID: 10-89653843-G-T

NM_000314.4(PTEN):c.141G>T;(p.R47S)

This variant was identified in 8 publications

View GRCh38 version.




Publications:


Germline and somatic variants in ovarian carcinoma: A next-generation sequencing (NGS) analysis.

Frontiers In Oncology
Andrikopoulou, Angeliki A; Zografos, Eleni E; Apostolidou, Kleoniki K; Kyriazoglou, Anastasios A; Papatheodoridi, Alksistis-Maria AM; Kaparelou, Maria M; Koutsoukos, Konstantinos K; Liontos, Michalis M; Dimopoulos, Meletios-Athanasios MA; Zagouri, Flora F
Publication Date: 2022

Variant appearance in text: PTEN: 141G>T; Arg47Ser
PubMed Link: 36531003
Variant Present in the following documents:
  • Main text
  • fonc-12-1030786.pdf
View BVdb publication page



GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types.

Acta Neuropathologica
Sievers, Philipp P; Stichel, Damian D; Sill, Martin M; Schrimpf, Daniel D; Sturm, Dominik D; Selt, Florian F; Ecker, Jonas J; Kazdal, Daniel D; Miele, Evelina E; Kranendonk, Mariëtte E G MEG; Tops, Bastiaan B J BBJ; Kohlhof-Meinecke, Patricia P; Beschorner, Rudi R; Kramm, Christof M CM; Hasselblatt, Martin M; Reifenberger, Guido G; Capper, David D; Wesseling, Pieter P; Stenzinger, Albrecht A; Milde, Till T; Korshunov, Andrey A; Witt, Olaf O; Pfister, Stefan M SM; Wick, Wolfgang W; von Deimling, Andreas A; Jones, David T W DTW; Sahm, Felix F
Publication Date: 2021-12

Variant appearance in text: PTEN: R47S
PubMed Link: 34536122
Variant Present in the following documents:
  • 401_2021_2369_MOESM1_ESM.pdf
View BVdb publication page



Phase and context shape the function of composite oncogenic mutations.

Nature
Gorelick, Alexander N AN; Sánchez-Rivera, Francisco J FJ; Cai, Yanyan Y; Bielski, Craig M CM; Biederstedt, Evan E; Jonsson, Philip P; Richards, Allison L AL; Vasan, Neil N; Penson, Alexander V AV; Friedman, Noah D ND; Ho, Yu-Jui YJ; Baslan, Timour T; Bandlamudi, Chaitanya C; Scaltriti, Maurizio M; Schultz, Nikolaus N; Lowe, Scott W SW; Reznik, Ed E; Taylor, Barry S BS
Publication Date: 2020-06

Variant appearance in text: PTEN: R47S
PubMed Link: 32461694
Variant Present in the following documents:
  • NIHMS1582596-supplement-1582596_Supp_Tab1-5.xlsx, sheet 2
View BVdb publication page



Sequencing and curation strategies for identifying candidate glioblastoma treatments.

Bmc Medical Genomics
Frank, Mayu O MO; Koyama, Takahiko T; Rhrissorrakrai, Kahn K; Robine, Nicolas N; Utro, Filippo F; Emde, Anne-Katrin AK; Chen, Bo-Juen BJ; Arora, Kanika K; Shah, Minita M; Geiger, Heather H; Felice, Vanessa V; Dikoglu, Esra E; Rahman, Sadia S; Fang, Alice A; Vacic, Vladimir V; Bergmann, Ewa A EA; Vogel, Julia L Moore JLM; Reeves, Catherine C; Khaira, Depinder D; Calabro, Anthony A; Kim, Duyang D; Lamendola-Essel, Michelle F MF; Esteves, Cecilia C; Agius, Phaedra P; Stolte, Christian C; Boockvar, John J; Demopoulos, Alexis A; Placantonakis, Dimitris G DG; Golfinos, John G JG; Brennan, Cameron C; Bruce, Jeffrey J; Lassman, Andrew B AB; Canoll, Peter P; Grommes, Christian C; Daras, Mariza M; Diamond, Eli E; Omuro, Antonio A; Pentsova, Elena E; Orange, Dana E DE; Harvey, Stephen J SJ; Posner, Jerome B JB; Michelini, Vanessa V VV; Jobanputra, Vaidehi V; Zody, Michael C MC; Kelly, John J; Parida, Laxmi L; Wrzeszczynski, Kazimierz O KO; Royyuru, Ajay K AK; Darnell, Robert B RB
Publication Date: 2019-04-25

Variant appearance in text: PTEN: R47S
PubMed Link: 31023376
Variant Present in the following documents:
  • Main text
  • 12920_2019_Article_500.pdf
View BVdb publication page



Detection of neoantigen-specific T cells following a personalized vaccine in a patient with glioblastoma.

Oncoimmunology
Johanns, Tanner M TM; Miller, Christopher A CA; Liu, Connor J CJ; Perrin, Richard J RJ; Bender, Diane D; Kobayashi, Dale K DK; Campian, Jian L JL; Chicoine, Michael R MR; Dacey, Ralph G RG; Huang, Jiayi J; Fritsch, Edward F EF; Gillanders, William E WE; Artyomov, Maxim N MN; Mardis, Elaine R ER; Schreiber, Robert D RD; Dunn, Gavin P GP
Publication Date: 2019

Variant appearance in text: PTEN: R47S
PubMed Link: 30906654
Variant Present in the following documents:
  • Main text
  • koni-08-04-1561106-s001.xlsx, sheet 1
  • koni-08-04-1561106.pdf
View BVdb publication page



Genomic Characterization of TP53-Wild-Type Esophageal Carcinoma.

Translational Oncology
Quaas, Alexander A; Heydt, Carina C; Gebauer, Florian F; Alakus, Hakan H; Loeser, Heike H; Buettner, Reinhard R; Hillmer, Axel A; Bruns, Christiane C; Merkelbach-Bruse, Sabine S; Zander, Thomas T; Frommolt, Peter P
Publication Date: 2019-01

Variant appearance in text: PTEN: R47S
PubMed Link: 30317074
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma.

Cell Reports
Giannakis, Marios M; Mu, Xinmeng Jasmine XJ; Shukla, Sachet A SA; Qian, Zhi Rong ZR; Cohen, Ofir O; Nishihara, Reiko R; Bahl, Samira S; Cao, Yin Y; Amin-Mansour, Ali A; Yamauchi, Mai M; Sukawa, Yasutaka Y; Stewart, Chip C; Rosenberg, Mara M; Mima, Kosuke K; Inamura, Kentaro K; Nosho, Katsuhiko K; Nowak, Jonathan A JA; Lawrence, Michael S MS; Giovannucci, Edward L EL; Chan, Andrew T AT; Ng, Kimmie K; Meyerhardt, Jeffrey A JA; Van Allen, Eliezer M EM; Getz, Gad G; Gabriel, Stacey B SB; Lander, Eric S ES; Wu, Catherine J CJ; Fuchs, Charles S CS; Ogino, Shuji S; Garraway, Levi A LA
Publication Date: 2016-04-26

Variant appearance in text: PTEN: R47S
PubMed Link: 27149842
Variant Present in the following documents:
  • mmc2.xlsx, sheet 4
View BVdb publication page



Optimal classes of chemotherapeutic agents sensitized by specific small-molecule inhibitors of akt in vitro and in vivo.

Neoplasia (New York, N.Y.)
Shi, Yan Y; Liu, Xuesong X; Han, Edward K EK; Guan, Ran R; Shoemaker, Alexander R AR; Oleksijew, Anatol A; Woods, Keith W KW; Fisher, John P JP; Klinghofer, Vered V; Lasko, Loren L; McGonigal, Thomas T; Li, Qun Q; Rosenberg, Saul H SH; Giranda, Vincent L VL; Luo, Yan Y
Publication Date: 2005-11

Variant appearance in text: PTEN: R47S
PubMed Link: 16331885
Variant Present in the following documents:
  • Main text
View BVdb publication page