Publications:

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Beta-blockers disrupt mitochondrial bioenergetics and increase radiotherapy efficacy independently of beta-adrenergic receptors in medulloblastoma.

Ebiomedicine

Rossi, Maïlys M; Talbot, Julie J; Piris, Patricia P; Grand, Marion Le ML; Montero, Marie-Pierre MP; Matteudi, Mélanie M; Agavnian-Couquiaud, Emilie E; Appay, Romain R; Keime, Céline C; Williamson, Daniel D; Buric, Duje D; Bourgarel, Véronique V; Padovani, Laetitia L; Clifford, Steven C SC; Ayrault, Olivier O; Pasquier, Eddy E; André, Nicolas N; Carré, Manon M

Publication Date: 2022-08

Variant appearance in text: PTEN: R55fs*1

PubMed Link: 35816899

Variant Present in the following documents:

• mmc4.pdf

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The genomic landscapes of individual melanocytes from human skin.

Nature

Tang, Jessica J; Fewings, Eleanor E; Chang, Darwin D; Zeng, Hanlin H; Liu, Shanshan S; Jorapur, Aparna A; Belote, Rachel L RL; McNeal, Andrew S AS; Tan, Tuyet M TM; Yeh, Iwei I; Arron, Sarah T ST; Judson-Torres, Robert L RL; Bastian, Boris C BC; Shain, A Hunter AH

Publication Date: 2020-10

Variant appearance in text: PTEN: R55fs*1

PubMed Link: 33029006

Variant Present in the following documents:

• NIHMS1626314-supplement-1626314_SuppTable3.xlsx, sheet 2

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The genetic evolution of metastatic uveal melanoma.

Nature Genetics

Shain, A Hunter AH; Bagger, Mette M MM; Yu, Richard R; Chang, Darwin D; Liu, Shanshan S; Vemula, Swapna S; Weier, Jingly F JF; Wadt, Karin K; Heegaard, Steffen S; Bastian, Boris C BC; Kiilgaard, Jens F JF

Publication Date: 2019-07

Variant appearance in text: PTEN: R55fs*1

PubMed Link: 31253977

Variant Present in the following documents:

• NIHMS1529305-supplement-5.xlsx, sheet 1

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Genetic alterations of triple negative breast cancer by targeted next-generation sequencing and correlation with tumor morphology.

Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc

Weisman, Paul S PS; Ng, Charlotte K Y CK; Brogi, Edi E; Eisenberg, Rachel E RE; Won, Helen H HH; Piscuoglio, Salvatore S; De Filippo, Maria R MR; Ioris, Rafael R; Akram, Muzaffar M; Norton, Larry L; Weigelt, Britta B; Berger, Michael F MF; Reis-Filho, Jorge S JS; Wen, Hannah Y HY

Publication Date: 2016-05

Variant appearance in text: PTEN: R55fs*1

PubMed Link: 26939876

Variant Present in the following documents:

• NIHMS752475-supplement-3.xlsx, sheet 1

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A network flow-based method to predict anticancer drug sensitivity.

Plos One

Qin, Yufang Y; Chen, Ming M; Wang, Haiyun H; Zheng, Xiaoqi X

Publication Date: 2015

Variant appearance in text: PTEN: R55fs*1

PubMed Link: 25992881

Variant Present in the following documents:

• pone.0127380.s002.xlsx, sheet 1

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Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets.

Nature Communications

Witkiewicz, Agnieszka K AK; McMillan, Elizabeth A EA; Balaji, Uthra U; Baek, GuemHee G; Lin, Wan-Chi WC; Mansour, John J; Mollaee, Mehri M; Wagner, Kay-Uwe KU; Koduru, Prasad P; Yopp, Adam A; Choti, Michael A MA; Yeo, Charles J CJ; McCue, Peter P; White, Michael A MA; Knudsen, Erik S ES

Publication Date: 2015-04-09

Variant appearance in text: PTEN: R55fs*1

PubMed Link: 25855536

Variant Present in the following documents:

• ncomms7744-s2.xlsx, sheet 1

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Target enrichment using parallel nanoliter quantitative PCR amplification.

Bmc Genomics

De Wilde, Bram B; Lefever, Steve S; Dong, Wes W; Dunne, Jude J; Husain, Syed S; Derveaux, Stefaan S; Hellemans, Jan J; Vandesompele, Jo J

Publication Date: 2014-03-10

Variant appearance in text: PTEN: R55fs*1

PubMed Link: 24612714

Variant Present in the following documents:

• Main text
• 1471-2164-15-184.pdf

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Synthetic lethal targeting of PTEN-deficient cancer cells using selective disruption of polynucleotide kinase/phosphatase.

Molecular Cancer Therapeutics

Mereniuk, Todd R TR; El Gendy, Mohamed A M MA; Mendes-Pereira, Ana M AM; Lord, Christopher J CJ; Ghosh, Sunita S; Foley, Edan E; Ashworth, Alan A; Weinfeld, Michael M

Publication Date: 2013-10

Variant appearance in text: PTEN: R55fs*1

PubMed Link: 23883586

Variant Present in the following documents:

• Main text

View BVdb publication page

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Systematic identification of genomic markers of drug sensitivity in cancer cells.

Nature

Garnett, Mathew J MJ; Edelman, Elena J EJ; Heidorn, Sonja J SJ; Greenman, Chris D CD; Dastur, Anahita A; Lau, King Wai KW; Greninger, Patricia P; Thompson, I Richard IR; Luo, Xi X; Soares, Jorge J; Liu, Qingsong Q; Iorio, Francesco F; Surdez, Didier D; Chen, Li L; Milano, Randy J RJ; Bignell, Graham R GR; Tam, Ah T AT; Davies, Helen H; Stevenson, Jesse A JA; Barthorpe, Syd S; Lutz, Stephen R SR; Kogera, Fiona F; Lawrence, Karl K; McLaren-Douglas, Anne A; Mitropoulos, Xeni X; Mironenko, Tatiana T; Thi, Helen H; Richardson, Laura L; Zhou, Wenjun W; Jewitt, Frances F; Zhang, Tinghu T; O'Brien, Patrick P; Boisvert, Jessica L JL; Price, Stacey S; Hur, Wooyoung W; Yang, Wanjuan W; Deng, Xianming X; Butler, Adam A; Choi, Hwan Geun HG; Chang, Jae Won JW; Baselga, Jose J; Stamenkovic, Ivan I; Engelman, Jeffrey A JA; Sharma, Sreenath V SV; Delattre, Olivier O; Saez-Rodriguez, Julio J; Gray, Nathanael S NS; Settleman, Jeffrey J; Futreal, P Andrew PA; Haber, Daniel A DA; Stratton, Michael R MR; Ramaswamy, Sridhar S; McDermott, Ultan U; Benes, Cyril H CH

Publication Date: 2012-03-28

Variant appearance in text: PTEN: R55fs*1

PubMed Link: 22460902

Variant Present in the following documents:

• NIHMS47188-supplement-supp_data.xlsx, sheet 2

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Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors.

Embo Molecular Medicine

Mendes-Pereira, Ana M AM; Martin, Sarah A SA; Brough, Rachel R; McCarthy, Afshan A; Taylor, Jessica R JR; Kim, Jung-Sik JS; Waldman, Todd T; Lord, Christopher J CJ; Ashworth, Alan A

Publication Date: 2009-09

Variant appearance in text: PTEN: R55fs*1

PubMed Link: 20049735

Variant Present in the following documents:

• Main text
• emmm0001-0315.pdf

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