Publications:

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Refinement of evolutionary medicine predictions based on clinical evidence for the manifestations of Mendelian diseases.

Scientific Reports

Šimčíková, Daniela D; Heneberg, Petr P

Publication Date: 2019-12-09

Variant appearance in text: PTEN: C124A

PubMed Link: 31819097

Variant Present in the following documents:

• 41598_2019_54976_MOESM2_ESM.xlsx, sheet 8

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AXL/AKT axis mediated-resistance to BRAF inhibitor depends on PTEN status in melanoma.

Oncogene

Zuo, Qiang Q; Liu, Jing J; Huang, Liping L; Qin, Yifei Y; Hawley, Teresa T; Seo, Claire C; Merlino, Glenn G; Yu, Yanlin Y

Publication Date: 2018-06

Variant appearance in text: PTEN: C124A

PubMed Link: 29551771

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• Main text

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Liver X receptors constrain tumor development and metastasis dissemination in PTEN-deficient prostate cancer.

Nature Communications

Alioui, Anthony A; Dufour, Julie J; Leoni, Valerio V; Loregger, Anke A; Moeton, Martina M; Iuliano, Luigi L; Zerbinati, Chiara C; Septier, Amandine A; Val, Pierre P; Fouache, Allan A; Russo, Vincenzo V; Volle, David H DH; Lobaccaro, Jean-Marc A JA; Zelcer, Noam N; Baron, Silvère S

Publication Date: 2017-09-05

Variant appearance in text: PTEN: C124A

PubMed Link: 28874658

Variant Present in the following documents:

• Main text
• 41467_2017_Article_508.pdf

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PTEN Inhibits Cell Proliferation, Promotes Cell Apoptosis, and Induces Cell Cycle Arrest via Downregulating the PI3K/AKT/hTERT Pathway in Lung Adenocarcinoma A549 Cells.

Biomed Research International

Lu, Xiao-Xiao XX; Cao, Lan-Yu LY; Chen, Xi X; Xiao, Jian J; Zou, Yong Y; Chen, Qiong Q

Publication Date: 2016

Variant appearance in text: PTEN: C124A

PubMed Link: 27822469

Variant Present in the following documents:

• Main text

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Association between TLR4 and PTEN Involved in LPS-TLR4 Signaling Response.

Biomed Research International

Yin, Huahua H; Tan, Yan Y; Wu, Xiaofeng X; Yan, Hong H; Liu, Feng F; Yao, Yuanzhang Y; Jiang, Jianxin J; Wan, Qi Q; Li, Lei L

Publication Date: 2016

Variant appearance in text: PTEN: C124A

PubMed Link: 27563672

Variant Present in the following documents:

• Main text
• BMRI2016-6083178.pdf

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Regulation of nuclear TDP-43 by NR2A-containing NMDA receptors and PTEN.

Journal Of Cell Science

Zheng, Mei M; Liao, Mingxia M; Cui, Tianyuan T; Tian, Honglin H; Fan, Dong-Sheng DS; Wan, Qi Q

Publication Date: 2012-03-15

Variant appearance in text: PTEN: C124A

PubMed Link: 22526419

Variant Present in the following documents:

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The chaperone-assisted E3 ligase C terminus of Hsc70-interacting protein (CHIP) targets PTEN for proteasomal degradation.

The Journal Of Biological Chemistry

Ahmed, Syed Feroj SF; Deb, Satamita S; Paul, Indranil I; Chatterjee, Anirban A; Mandal, Tapashi T; Chatterjee, Uttara U; Ghosh, Mrinal K MK

Publication Date: 2012-05-04

Variant appearance in text: PTEN: C124A

PubMed Link: 22427670

Variant Present in the following documents:

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NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration.

Molecular Neurodegeneration

Kwak, Young-Don YD; Ma, Tao T; Diao, Shiyong S; Zhang, Xue X; Chen, Yaomin Y; Hsu, Janet J; Lipton, Stuart A SA; Masliah, Eliezer E; Xu, Huaxi H; Liao, Francesca-Fang FF

Publication Date: 2010-11-10

Variant appearance in text: PTEN: C124A

PubMed Link: 21067594

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• Main text
• 1750-1326-5-49.pdf

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Inactivation of the tumour suppressor, PTEN, in smooth muscle promotes a pro-inflammatory phenotype and enhances neointima formation.

Cardiovascular Research

Furgeson, Seth B SB; Simpson, Peter A PA; Park, Insun I; Vanputten, Vicki V; Horita, Henrick H; Kontos, Christopher D CD; Nemenoff, Raphael A RA; Weiser-Evans, Mary C M MC

Publication Date: 2010-05-01

Variant appearance in text: PTEN: C124A

PubMed Link: 20051384

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Inhibition of endothelial nitric oxide synthase by the lipid phosphatase PTEN.

Vascular Pharmacology

Church, Jarrod E JE; Qian, Jin J; Kumar, Sanjiv S; Black, Stephen M SM; Venema, Richard C RC; Papapetropoulos, Andreas A; Fulton, David J R DJ

Publication Date: 2010

Variant appearance in text: PTEN: C124A

PubMed Link: 19962452

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Dual neuroprotective signaling mediated by downregulating two distinct phosphatase activities of PTEN.

The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience

Ning, Ke K; Pei, Lin L; Liao, Mingxia M; Liu, Baosong B; Zhang, Yunzhou Y; Jiang, Wen W; Mielke, John G JG; Li, Lei L; Chen, Yonghong Y; El-Hayek, Youssef H YH; Fehlings, Michael G MG; Zhang, Xia X; Liu, Fang F; Eubanks, James J; Wan, Qi Q

Publication Date: 2004-04-21

Variant appearance in text: PTEN: C124A

PubMed Link: 15102920

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Membrane-binding and activation mechanism of PTEN.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Das, Sudipto S; Dixon, Jack E JE; Cho, Wonhwa W

Publication Date: 2003-06-24

Variant appearance in text: PTEN: C124A

PubMed Link: 12808147

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The lipid phosphatase activity of PTEN is critical for stabilizing intercellular junctions and reverting invasiveness.

The Journal Of Cell Biology

Kotelevets, L L; van Hengel, J J; Bruyneel, E E; Mareel, M M; van Roy, F F; Chastre, E E

Publication Date: 2001-12-24

Variant appearance in text: PTEN: C124A

PubMed Link: 11756467

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Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways.

The Journal Of Cell Biology

Gu, J J; Tamura, M M; Yamada, K M KM

Publication Date: 1998-11-30

Variant appearance in text: PTEN: C124A

PubMed Link: 9832564

Variant Present in the following documents:

• Main text
• 9807101.pdf

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