PTEN c.490_491delinsGC ;(p.K164A)

Variant ID: 10-89693006-AA-GC

NM_000314.4(PTEN):c.490_491delinsGC;(p.K164A)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


PTEN stabilizes TOP2A and regulates the DNA decatenation.

Scientific Reports
Kang, Xi X; Song, Chang C; Du, Xiao X; Zhang, Cong C; Liu, Yu Y; Liang, Ling L; He, Jinxue J; Lamb, Kristy K; Shen, Wen H WH; Yin, Yuxin Y
Publication Date: 2015-12-10

Variant appearance in text: PTEN: K164A
PubMed Link: 26657567
Variant Present in the following documents:
  • Main text
  • srep17873-s1.pdf
  • srep17873.pdf
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A new family of phosphoinositide phosphatases in microorganisms: identification and biochemical analysis.

Bmc Genomics
Beresford, Nicola J NJ; Saville, Charis C; Bennett, Hayley J HJ; Roberts, Ian S IS; Tabernero, Lydia L
Publication Date: 2010-08-02

Variant appearance in text: PTEN: K164A
PubMed Link: 20678187
Variant Present in the following documents:
  • Main text
  • 1471-2164-11-457.pdf
View BVdb publication page



A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Rahdar, Meghdad M; Inoue, Takanari T; Meyer, Tobias T; Zhang, Jin J; Vazquez, Francisca F; Devreotes, Peter N PN
Publication Date: 2009-01-13

Variant appearance in text: PTEN: K164A
PubMed Link: 19114656
Variant Present in the following documents:
  • Main text
View BVdb publication page



MptpB, a virulence factor from Mycobacterium tuberculosis, exhibits triple-specificity phosphatase activity.

The Biochemical Journal
Beresford, Nicola N; Patel, Sumayya S; Armstrong, Jane J; Szöor, Balázs B; Fordham-Skelton, Anthony P AP; Tabernero, Lydia L
Publication Date: 2007-08-15

Variant appearance in text: PTEN: K164A
PubMed Link: 17584180
Variant Present in the following documents:
  • Main text
View BVdb publication page



Nuclear localization of PTEN by a Ran-dependent mechanism enhances apoptosis: Involvement of an N-terminal nuclear localization domain and multiple nuclear exclusion motifs.

Molecular Biology Of The Cell
Gil, Anabel A; Andrés-Pons, Amparo A; Fernández, Elena E; Valiente, Miguel M; Torres, Josema J; Cervera, Javier J; Pulido, Rafael R
Publication Date: 2006-09

Variant appearance in text: PTEN: K164A
PubMed Link: 16807353
Variant Present in the following documents:
  • Main text
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Membrane-binding and activation mechanism of PTEN.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Das, Sudipto S; Dixon, Jack E JE; Cho, Wonhwa W
Publication Date: 2003-06-24

Variant appearance in text: PTEN: K164A
PubMed Link: 12808147
Variant Present in the following documents:
  • Main text
View BVdb publication page