PTEN c.492+7663G>A

Variant ID: 10-89700671-G-A

NM_000314.4(PTEN):c.492+7663G>A

This variant was identified in 10 publications

View GRCh38 version.




Publications:


Genetic variations in the PI3K/PTEN/AKT/mTOR pathway predict tumor response and disease-free survival in locally advanced rectal cancer patients receiving preoperative chemoradiotherapy and radical surgery.

Journal Of Cancer
Peng, Jianhong J; Ma, Wenjuan W; Zhou, Zhongguo Z; Gu, Yangkui Y; Lu, Zhenhai Z; Zhang, Rongxin R; Pan, Zhizhong Z
Publication Date: 2018

Variant appearance in text: rs12357281
PubMed Link: 29581786
Variant Present in the following documents:
  • Main text
  • jcav09p1067.pdf
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Functional PTGS2 polymorphism-based models as novel predictive markers in metastatic renal cell carcinoma patients receiving first-line sunitinib.

Scientific Reports
Cebrián, Arancha A; Gómez Del Pulgar, Teresa T; Méndez-Vidal, María José MJ; Gonzálvez, María Luisa ML; Lainez, Nuria N; Castellano, Daniel D; García-Carbonero, Iciar I; Esteban, Emilio E; Sáez, Maria Isabel MI; Villatoro, Rosa R; Suárez, Cristina C; Carrato, Alfredo A; Munárriz-Ferrándiz, Javier J; Basterrechea, Laura L; García-Alonso, Mirta M; González-Larriba, José Luis JL; Perez-Valderrama, Begoña B; Cruz-Jurado, Josefina J; González Del Alba, Aránzazu A; Moreno, Fernando F; Reynés, Gaspar G; Rodríguez-Remírez, María M; Boni, Valentina V; Mahillo-Fernández, Ignacio I; Martin, Yolanda Y; Viqueira, Andrea A; García-Foncillas, Jesús J
Publication Date: 2017-01-24

Variant appearance in text: rs12357281
PubMed Link: 28117391
Variant Present in the following documents:
  • Main text
  • srep41371.pdf
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Sirolimus and Everolimus Pathway: Reviewing Candidate Genes Influencing Their Intracellular Effects.

International Journal Of Molecular Sciences
Granata, Simona S; Dalla Gassa, Alessandra A; Carraro, Amedeo A; Brunelli, Matteo M; Stallone, Giovanni G; Lupo, Antonio A; Zaza, Gianluigi G
Publication Date: 2016-05-14

Variant appearance in text: rs12357281
PubMed Link: 27187382
Variant Present in the following documents:
  • Main text
  • ijms-17-00735.pdf
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Association of genetic polymorphisms in PTEN and additional interaction with alcohol consumption and smoking on colorectal cancer in Chinese population.

International Journal Of Clinical And Experimental Medicine
Han, Mingyang M; Wu, Gang G; Sun, Peichun P; Nie, Jiewei J; Zhang, Jiancheng J; Li, Yuanyuan Y
Publication Date: 2015

Variant appearance in text: rs12357281
PubMed Link: 26885116
Variant Present in the following documents:
  • Main text
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Roles of genetic variants in the PI3K and RAS/RAF pathways in susceptibility to endometrial cancer and clinical outcomes.

Journal Of Cancer Research And Clinical Oncology
Wang, Li-E LE; Ma, Hongxia H; Hale, Katherine S KS; Yin, Ming M; Meyer, Larissa A LA; Liu, Hongliang H; Li, Jie J; Lu, Karen H KH; Hennessy, Bryan T BT; Li, Xuesong X; Spitz, Margaret R MR; Wei, Qingyi Q; Mills, Gordon B GB
Publication Date: 2012-03

Variant appearance in text: rs12357281
PubMed Link: 22146979
Variant Present in the following documents:
  • Main text
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Germ-line sequence variants of PTEN do not have an important role in hereditary and non-hereditary prostate cancer susceptibility.

Journal Of Human Genetics
Xie, Chunmei C CC; Lu, Lingyi L; Sun, Jielin J; Zheng, S Lilly SL; Isaacs, William B WB; Gronberg, Henrik H; Xu, Jianfeng J
Publication Date: 2011-07

Variant appearance in text: rs12357281
PubMed Link: 21633361
Variant Present in the following documents:
  • Main text
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Endometrial cancer and genetic variation in PTEN, PIK3CA, AKT1, MLH1, and MSH2 within a population-based case-control study.

Gynecologic Oncology
Lacey, James V JV; Yang, Hannah H; Gaudet, Mia M MM; Dunning, Alison A; Lissowska, Jolanta J; Sherman, Mark E ME; Peplonska, Beata B; Brinton, Louise A LA; Healey, Catherine S CS; Ahmed, Shahana S; Pharoah, Paul P; Easton, Douglas D; Chanock, Stephen S; Garcia-Closas, Montserrat M
Publication Date: 2011-02

Variant appearance in text: rs12357281
PubMed Link: 21093899
Variant Present in the following documents:
  • Main text
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PI3K/PTEN/AKT/mTOR pathway genetic variation predicts toxicity and distant progression in lung cancer patients receiving platinum-based chemotherapy.

Lung Cancer (Amsterdam, Netherlands)
Pu, Xia X; Hildebrandt, Michelle A T MA; Lu, Charles C; Lin, Jie J; Stewart, David J DJ; Ye, Yuanqing Y; Gu, Jian J; Spitz, Margaret R MR; Wu, Xifeng X
Publication Date: 2011-01

Variant appearance in text: rs12357281
PubMed Link: 20447721
Variant Present in the following documents:
  • Main text
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No association between phosphatase and tensin homolog genetic polymorphisms and colon cancer.

World Journal Of Gastroenterology
Phillips, Lynette S LS; Thompson, Cheryl L CL; Merkulova, Alona A; Plummer, Sarah J SJ; Tucker, Thomas C TC; Casey, Graham G; Li, Li L
Publication Date: 2009-08-14

Variant appearance in text: rs12357281
PubMed Link: 19673018
Variant Present in the following documents:
  • Main text
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Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy.

Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology
Hildebrandt, Michelle A T MA; Yang, Hushan H; Hung, Mien-Chie MC; Izzo, Julie G JG; Huang, Maosheng M; Lin, Jie J; Ajani, Jaffer A JA; Wu, Xifeng X
Publication Date: 2009-02-20

Variant appearance in text: rs12357281
PubMed Link: 19164214
Variant Present in the following documents:
  • Main text
View BVdb publication page