PTEN c.521A>T ;(p.Y174F)

Variant ID: 10-89711903-A-T

NM_000314.4(PTEN):c.521A>T;(p.Y174F)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


Regulation of the PI3K pathway through a p85α monomer-homodimer equilibrium.

Elife
Cheung, Lydia W T LW; Walkiewicz, Katarzyna W KW; Besong, Tabot M D TM; Guo, Huifang H; Hawke, David H DH; Arold, Stefan T ST; Mills, Gordon B GB
Publication Date: 2015-07-29

Variant appearance in text: PTEN: Y174F
PubMed Link: 26222500
Variant Present in the following documents:
  • Main text
  • elife06866.pdf
View BVdb publication page



Vav links the T cell antigen receptor to the actin cytoskeleton and T cell activation independently of intrinsic Guanine nucleotide exchange activity.

Plos One
Miletic, Ana V AV; Graham, Daniel B DB; Sakata-Sogawa, Kumiko K; Hiroshima, Michio M; Hamann, Michael J MJ; Cemerski, Saso S; Kloeppel, Tracie T; Billadeau, Daniel D DD; Kanagawa, Osami O; Tokunaga, Makio M; Swat, Wojciech W
Publication Date: 2009-08-12

Variant appearance in text: PTEN: Y174F
PubMed Link: 19672294
Variant Present in the following documents:
  • Main text
  • pone.0006599.pdf
View BVdb publication page