PTEN c.539A>T ;(p.Y180F)

Variant ID: 10-89711921-A-T

NM_000314.4(PTEN):c.539A>T;(p.Y180F)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Identification of predictors of drug sensitivity using patient-derived models of esophageal squamous cell carcinoma.

Nature Communications
Su, Dan D; Zhang, Dadong D; Jin, Jiaoyue J; Ying, Lisha L; Han, Miao M; Chen, Kaiyan K; Li, Bin B; Wu, Junzhou J; Xie, Zhenghua Z; Zhang, Fanrong F; Lin, Yihui Y; Cheng, Guoping G; Li, Jing-Yu JY; Huang, Minran M; Wang, Jinchao J; Wang, Kailai K; Zhang, Jianjun J; Li, Fugen F; Xiong, Lei L; Futreal, Andrew A; Mao, Weimin W
Publication Date: 2019-11-07

Variant appearance in text: PTEN: 539A>T
PubMed Link: 31700061
Variant Present in the following documents:
  • 41467_2019_12846_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: PTEN: Y180F
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 1
  • pone.0196434.s001.xlsx, sheet 3
View BVdb publication page



Conformational snapshots of Tec kinases during signaling.

Immunological Reviews
Joseph, Raji E RE; Andreotti, Amy H AH
Publication Date: 2009-03

Variant appearance in text: PTEN: Y180F
PubMed Link: 19290922
Variant Present in the following documents:
  • Main text
View BVdb publication page



Alteration of phosphatidylinositol 3-kinase cascade in the multilobulated nuclear formation of adult T cell leukemia/lymphoma (ATLL).

Proceedings Of The National Academy Of Sciences Of The United States Of America
Fukuda, Ryu-ichi R; Hayashi, Ayako A; Utsunomiya, Atae A; Nukada, Yuko Y; Fukui, Rie R; Itoh, Katsuhiko K; Tezuka, Katsunari K; Ohashi, Kazumasa K; Mizuno, Kensaku K; Sakamoto, Manabu M; Hamanoue, Masahiro M; Tsuji, Takashi T
Publication Date: 2005-10-18

Variant appearance in text: PTEN: Y180F
PubMed Link: 16217039
Variant Present in the following documents:
  • Main text
View BVdb publication page