PTEN c.649G>T ;(p.V217F)

Variant ID: 10-89717624-G-T

NM_000314.4(PTEN):c.649G>T;(p.V217F)

This variant was identified in 2 publications

View GRCh38 version.



Variant-Specific Resource Links:
gnomAD v2.1.1
Mutalizer Name Checker
Google
UCSC Genome Browser
ClinVar
dbSNP

Publications:

Co-occurrence CDK4/6 amplification serves as biomarkers of de novo EGFR TKI resistance in sensitizing EGFR mutation non-small cell lung cancer.

Scientific Reports
Sitthideatphaiboon, Piyada P; Teerapakpinyo, Chinachote C; Korphaisarn, Krittiya K; Leelayuwatanakul, Nophol N; Pornpatrananrak, Nopporn N; Poungvarin, Naravat N; Chantranuwat, Poonchavist P; Shuangshoti, Shanop S; Aporntewan, Chatchawit C; Chintanapakdee, Wariya W; Sriuranpong, Virote V; Vinayanuwattikun, Chanida C
Publication Date: 2022-02-09

Variant appearance in text: PTEN: V217F
PubMed Link: 35140316
Variant Present in the following documents:
  • 41598_2022_6239_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page


Co-occurrence CDK4/6 amplification serves as biomarkers of de novo EGFR TKI resistance in sensitizing EGFR mutation non-small cell lung cancer.

Scientific Reports
Sitthideatphaiboon, Piyada P; Teerapakpinyo, Chinachote C; Korphaisarn, Krittiya K; Leelayuwatanakul, Nophol N; Pornpatrananrak, Nopporn N; Poungvarin, Naravat N; Chantranuwat, Poonchavist P; Shuangshoti, Shanop S; Aporntewan, Chatchawit C; Chintanapakdee, Wariya W; Sriuranpong, Virote V; Vinayanuwattikun, Chanida C
Publication Date: 2022-02-09

Variant appearance in text: PTEN: V217F
PubMed Link: 35140316
Variant Present in the following documents:
  • 41598_2022_6239_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page


Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma.

Plos Medicine
Cloughesy, Tim F TF; Yoshimoto, Koji K; Nghiemphu, Phioanh P; Brown, Kevin K; Dang, Julie J; Zhu, Shaojun S; Hsueh, Teli T; Chen, Yinan Y; Wang, Wei W; Youngkin, David D; Liau, Linda L; Martin, Neil N; Becker, Don D; Bergsneider, Marvin M; Lai, Albert A; Green, Richard R; Oglesby, Tom T; Koleto, Michael M; Trent, Jeff J; Horvath, Steve S; Mischel, Paul S PS; Mellinghoff, Ingo K IK; Sawyers, Charles L CL
Publication Date: 2008-01-22

Variant appearance in text: PTEN: V217F
PubMed Link: 18215105
Variant Present in the following documents:
  • Main text
  • pmed.0050008.st002.pdf
View BVdb publication page