Publications:

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: PTEN: F257L

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

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Genomic landscape of the immunogenicity regulation in skin melanomas with diverse tumor mutation burden.

Frontiers In Immunology

Georgoulias, George G; Zaravinos, Apostolos A

Publication Date: 2022

Variant appearance in text: PTEN: F257L

PubMed Link: 36389735

Variant Present in the following documents:

• Table_7.xlsx, sheet 13

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Multi-omics data integration reveals novel drug targets in hepatocellular carcinoma.

Bmc Genomics

Dimitrakopoulos, Christos C; Hindupur, Sravanth Kumar SK; Colombi, Marco M; Liko, Dritan D; Ng, Charlotte K Y CKY; Piscuoglio, Salvatore S; Behr, Jonas J; Moore, Ariane L AL; Singer, Jochen J; Ruscheweyh, Hans-Joachim HJ; Matter, Matthias S MS; Mossmann, Dirk D; Terracciano, Luigi M LM; Hall, Michael N MN; Beerenwinkel, Niko N

Publication Date: 2021-08-04

Variant appearance in text: PTEN: 771C>A

PubMed Link: 34348664

Variant Present in the following documents:

• Main text

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Molecular profiling identifies synchronous endometrial and ovarian cancers as metastatic endometrial cancer with favorable clinical outcome.

International Journal Of Cancer

Reijnen, Casper C; Küsters-Vandevelde, Heidi V N HVN; Ligtenberg, Marjolijn J L MJL; Bulten, Johan J; Oosterwegel, Marloes M; Snijders, Marc P L M MPLM; Sweegers, Sanne S; de Hullu, Joanne A JA; Vos, Maria C MC; van der Wurff, Anneke A M AAM; van Altena, Anne M AM; Eijkelenboom, Astrid A; Pijnenborg, Johanna M A JMA

Publication Date: 2020-07-15

Variant appearance in text: PTEN: 771C>A; Phe257Leu

PubMed Link: 32022266

Variant Present in the following documents:

• IJC-147-478-s001.pdf

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Clinical genetic features and related survival implications in patients with surgically resected large-cell lung cancer.

Cancer Management And Research

Wang, Fang F; Lu, Jia-Bin JB; Wu, Xiao-Yan XY; Feng, Yan-Fen YF; Shao, Qiong Q; An, Xin X; Wang, Hai-Yun HY

Publication Date: 2019

Variant appearance in text: PTEN: F257L

PubMed Link: 31354355

Variant Present in the following documents:

• Main text

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Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response.

The Journal Of Pathology

Temko, Daniel D; Van Gool, Inge C IC; Rayner, Emily E; Glaire, Mark M; Makino, Seiko S; Brown, Matthew M; Chegwidden, Laura L; Palles, Claire C; Depreeuw, Jeroen J; Beggs, Andrew A; Stathopoulou, Chaido C; Mason, John J; Baker, Ann-Marie AM; Williams, Marc M; Cerundolo, Vincenzo V; Rei, Margarida M; Taylor, Jenny C JC; Schuh, Anna A; Ahmed, Ahmed A; Amant, Frédéric F; Lambrechts, Diether D; Smit, Vincent Thbm VT; Bosse, Tjalling T; Graham, Trevor A TA; Church, David N DN; Tomlinson, Ian I

Publication Date: 2018-07

Variant appearance in text: PTEN: 771C>A; F257L

PubMed Link: 29604063

Variant Present in the following documents:

• PATH-245-283-s020.xlsx, sheet 1
• PATH-245-283-s019.xlsx, sheet 1

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Sequencing of Lynch syndrome tumors reveals the importance of epigenetic alterations.

Oncotarget

Porkka, Noora N; Valo, Satu S; Nieminen, Taina T TT; Olkinuora, Alisa A; Mäki-Nevala, Satu S; Eldfors, Samuli S; Peltomäki, Päivi P

Publication Date: 2017-12-08

Variant appearance in text: PTEN: F257L

PubMed Link: 29296220

Variant Present in the following documents:

• oncotarget-08-108020-s006.xlsx, sheet 1

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Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research

Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C

Publication Date: 2011-09-01

Variant appearance in text: PTEN: F257L

PubMed Link: 21727090

Variant Present in the following documents:

• supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1

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