Publications:

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Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: PTEN: 865A>G; Lys289Glu

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics

G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A

Publication Date: 2022

Variant appearance in text: PTEN: K289E

PubMed Link: 36561320

Variant Present in the following documents:

• Table2.xlsx, sheet 6
• Table3.xlsx, sheet 1

View BVdb publication page

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Smurf1 Suppression Enhances Temozolomide Chemosensitivity in Glioblastoma by Facilitating PTEN Nuclear Translocation.

Cells

Dong, Lei L; Li, Yang Y; Liu, Liqun L; Meng, Xinyi X; Li, Shengzhen S; Han, Da D; Xiao, Zhenyu Z; Xia, Qin Q

Publication Date: 2022-10-20

Variant appearance in text: PTEN: K289E

PubMed Link: 36291166

Variant Present in the following documents:

• Main text
• cells-11-03302.pdf

View BVdb publication page

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Identification of Immune-Related Gene Signatures in Lung Adenocarcinoma and Lung Squamous Cell Carcinoma.

Frontiers In Immunology

Li, Na N; Wang, Jiahong J; Zhan, Xianquan X

Publication Date: 2021

Variant appearance in text: PTEN: 865A>G; Lys289Glu

PubMed Link: 34887858

Variant Present in the following documents:

• Table_4.xlsx, sheet 1

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: PTEN: K289E

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases.

Scientific Reports

Magraner-Pardo, Lorena L; Laskowski, Roman A RA; Pons, Tirso T; Thornton, Janet M JM

Publication Date: 2021-07-12

Variant appearance in text: rs562015640

PubMed Link: 34253785

Variant Present in the following documents:

• 41598_2021_93715_MOESM3_ESM.xlsx, sheet 4
• 41598_2021_93715_MOESM3_ESM.xlsx, sheet 6
• 41598_2021_93715_MOESM3_ESM.xlsx, sheet 2
• 41598_2021_93715_MOESM3_ESM.xlsx, sheet 5

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The Skin in Cowden Syndrome.

Frontiers In Medicine

Lim, Agnes A; Ngeow, Joanne J

Publication Date: 2021

Variant appearance in text: PTEN: Lys289Glu

PubMed Link: 34179044

Variant Present in the following documents:

• Main text
• fmed-08-658842.pdf

View BVdb publication page

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Mutation-specific non-canonical pathway of PTEN as a distinct therapeutic target for glioblastoma.

Cell Death & Disease

Choi, Seung Won SW; Lee, Yeri Y; Shin, Kayoung K; Koo, Harim H; Kim, Donggeon D; Sa, Jason K JK; Cho, Hee Jin HJ; Shin, Hye-Mi HM; Lee, Se Jeong SJ; Kim, Hyunho H; Chung, Seok S; Shin, Jihye J; Lee, Cheolju C; Nam, Do-Hyun DH

Publication Date: 2021-04-07

Variant appearance in text: PTEN: K289E

PubMed Link: 33828082

Variant Present in the following documents:

• Main text
• 41419_2021_Article_3657.pdf

View BVdb publication page

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Role of Ubiquitination in PTEN Cellular Homeostasis and Its Implications in GB Drug Resistance.

Frontiers In Oncology

Xia, Qin Q; Ali, Sakhawat S; Liu, Liqun L; Li, Yang Y; Liu, Xuefeng X; Zhang, Lingqiang L; Dong, Lei L

Publication Date: 2020

Variant appearance in text: PTEN: K289E

PubMed Link: 32984016

Variant Present in the following documents:

• Main text
• fonc-10-01569.pdf

View BVdb publication page

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An Integrated Deep-Mutational-Scanning Approach Provides Clinical Insights on PTEN Genotype-Phenotype Relationships.

American Journal Of Human Genetics

Mighell, Taylor L TL; Thacker, Stetson S; Fombonne, Eric E; Eng, Charis C; O'Roak, Brian J BJ

Publication Date: 2020-06-04

Variant appearance in text: PTEN: 865A>G; Lys289Glu

PubMed Link: 32442409

Variant Present in the following documents:

• Main text

View BVdb publication page

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: PTEN: K289E

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

View BVdb publication page

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An update on PTEN modulators - a patent review.

Expert Opinion On Therapeutic Patents

Boosani, Chandra S CS; Gunasekar, Palanikumar P; Agrawal, Devendra K DK

Publication Date: 2019-11

Variant appearance in text: PTEN: K289E

PubMed Link: 31530116

Variant Present in the following documents:

• Main text

View BVdb publication page

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REVEL and BayesDel outperform other in silico meta-predictors for clinical variant classification.

Scientific Reports

Tian, Yuan Y; Pesaran, Tina T; Chamberlin, Adam A; Fenwick, R Bryn RB; Li, Shuwei S; Gau, Chia-Ling CL; Chao, Elizabeth C EC; Lu, Hsiao-Mei HM; Black, Mary Helen MH; Qian, Dajun D

Publication Date: 2019-09-04

Variant appearance in text: PTEN: 865A>G; K289E

PubMed Link: 31484976

Variant Present in the following documents:

• 41598_2019_49224_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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The Impact of Genetic Variants on PTEN Molecular Functions and Cellular Phenotypes.

Cold Spring Harbor Perspectives In Medicine

Hasle, Nicholas N; Matreyek, Kenneth A KA; Fowler, Douglas M DM

Publication Date: 2019-11-01

Variant appearance in text: PTEN: K289E

PubMed Link: 31451538

Variant Present in the following documents:

• Main text

View BVdb publication page

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Systematic analysis of the intersection of disease mutations with protein modifications.

Bmc Medical Genomics

Simpson, Claire M CM; Zhang, Bin B; Hornbeck, Peter V PV; Gnad, Florian F

Publication Date: 2019-07-25

Variant appearance in text: PTEN: K289E

PubMed Link: 31345222

Variant Present in the following documents:

• 12920_2019_543_MOESM5_ESM.xlsx, sheet 1
• 12920_2019_543_MOESM6_ESM.xlsx, sheet 3

View BVdb publication page

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PTEN-opathies: from biological insights to evidence-based precision medicine.

The Journal Of Clinical Investigation

Yehia, Lamis L; Ngeow, Joanne J; Eng, Charis C

Publication Date: 2019-02-01

Variant appearance in text: PTEN: Lys289Glu

PubMed Link: 30614812

Variant Present in the following documents:

• Main text

View BVdb publication page

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A Bayesian framework for efficient and accurate variant prediction.

Plos One

Qian, Dajun D; Li, Shuwei S; Tian, Yuan Y; Clifford, Jacob W JW; Sarver, Brice A J BAJ; Pesaran, Tina T; Gau, Chia-Ling CL; Elliott, Aaron M AM; Lu, Hsiao-Mei HM; Black, Mary Helen MH

Publication Date: 2018

Variant appearance in text: PTEN: 865A>G; K289E

PubMed Link: 30212499

Variant Present in the following documents:

• pone.0203553.s008.xlsx, sheet 2

View BVdb publication page

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PTEN: Tumor Suppressor and Metabolic Regulator.

Frontiers In Endocrinology

Chen, Chien-Yu CY; Chen, Jingyu J; He, Lina L; Stiles, Bangyan L BL

Publication Date: 2018

Variant appearance in text: PTEN: K289E

PubMed Link: 30038596

Variant Present in the following documents:

• Main text
• fendo-09-00338.pdf

View BVdb publication page

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A Saturation Mutagenesis Approach to Understanding PTEN Lipid Phosphatase Activity and Genotype-Phenotype Relationships.

American Journal Of Human Genetics

Mighell, Taylor L TL; Evans-Dutson, Sara S; O'Roak, Brian J BJ

Publication Date: 2018-05-03

Variant appearance in text: PTEN: Lys289Glu

PubMed Link: 29706350

Variant Present in the following documents:

• Main text

View BVdb publication page

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Identification of a PTEN mutation with reduced protein stability, phosphatase activity, and nuclear localization in Hong Kong patients with autistic features, neurodevelopmental delays, and macrocephaly.

Autism Research : Official Journal Of The International Society For Autism Research

Wong, Chi Wai CW; Or, Penelope Mei Yu PMY; Wang, Yubing Y; Li, Lisha L; Li, Jing J; Yan, Mingfei M; Cao, Ye Y; Luk, Ho Ming HM; Tong, Tony Ming For TMF; Leslie, Nick R NR; Lo, Ivan Fai-Man IF; Choy, Kwong Wai KW; Chan, Andrew Man Lok AML

Publication Date: 2018-08

Variant appearance in text: PTEN: K289E

PubMed Link: 29608813

Variant Present in the following documents:

• Main text
• AUR-11-1098.pdf

View BVdb publication page

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Nuclear Excluded Autism-Associated Phosphatase and Tensin Homolog Mutations Dysregulate Neuronal Growth.

Biological Psychiatry

Fricano-Kugler, Catherine J CJ; Getz, Stephanie A SA; Williams, Michael R MR; Zurawel, Ashley A AA; DeSpenza, Tyrone T; Frazel, Paul W PW; Li, Meijie M; O'Malley, Alistair J AJ; Moen, Erika L EL; Luikart, Bryan W BW

Publication Date: 2018-08-15

Variant appearance in text: PTEN: K289E

PubMed Link: 29373119

Variant Present in the following documents:

• Main text

View BVdb publication page

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Sources of discordance among germ-line variant classifications in ClinVar.

Genetics In Medicine : Official Journal Of The American College Of Medical Genetics

Yang, Shan S; Lincoln, Stephen E SE; Kobayashi, Yuya Y; Nykamp, Keith K; Nussbaum, Robert L RL; Topper, Scott S

Publication Date: 2017-10

Variant appearance in text: PTEN: 865A>G; Lys289Glu

PubMed Link: 28569743

Variant Present in the following documents:

• gim201760x7.xlsx, sheet 2

View BVdb publication page

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The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein.

The Journal Of Cell Biology

Chen, Muhan M; Nowak, Dawid G DG; Narula, Navneet N; Robinson, Brian B; Watrud, Kaitlin K; Ambrico, Alexandra A; Herzka, Tali M TM; Zeeman, Martha E ME; Minderer, Matthias M; Zheng, Wu W; Ebbesen, Saya H SH; Plafker, Kendra S KS; Stahlhut, Carlos C; Wang, Victoria M Y VM; Wills, Lorna L; Nasar, Abu A; Castillo-Martin, Mireia M; Cordon-Cardo, Carlos C; Wilkinson, John E JE; Powers, Scott S; Sordella, Raffaella R; Altorki, Nasser K NK; Mittal, Vivek V; Stiles, Brendon M BM; Plafker, Scott M SM; Trotman, Lloyd C LC

Publication Date: 2017-03-06

Variant appearance in text: PTEN: K289E

PubMed Link: 28193700

Variant Present in the following documents:

• Main text
• JCB_201604025.pdf
• JCB_201604025_sm.pdf

View BVdb publication page

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Exome sequencing covers >98% of mutations identified on targeted next generation sequencing panels.

Plos One

LaDuca, Holly H; Farwell, Kelly D KD; Vuong, Huy H; Lu, Hsiao-Mei HM; Mu, Wenbo W; Shahmirzadi, Layla L; Tang, Sha S; Chen, Jefferey J; Bhide, Shruti S; Chao, Elizabeth C EC

Publication Date: 2017

Variant appearance in text: PTEN: 865A>G; K289E

PubMed Link: 28152038

Variant Present in the following documents:

• pone.0170843.s003.xlsx, sheet 1
• pone.0170843.s004.xlsx, sheet 1

View BVdb publication page

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PTEN regulates EG5 to control spindle architecture and chromosome congression during mitosis.

Nature Communications

He, Jinxue J; Zhang, Zhong Z; Ouyang, Meng M; Yang, Fan F; Hao, Hongbo H; Lamb, Kristy L KL; Yang, Jingyi J; Yin, Yuxin Y; Shen, Wen H WH

Publication Date: 2016-08-05

Variant appearance in text: PTEN: K289E

PubMed Link: 27492783

Variant Present in the following documents:

• ncomms12355.pdf

View BVdb publication page

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A systematic screening to identify de novo mutations causing sporadic early-onset Parkinson's disease.

Human Molecular Genetics

Kun-Rodrigues, Celia C; Ganos, Christos C; Guerreiro, Rita R; Schneider, Susanne A SA; Schulte, Claudia C; Lesage, Suzanne S; Darwent, Lee L; Holmans, Peter P; Singleton, Andrew A; , ; Bhatia, Kailash K; Bras, Jose J

Publication Date: 2015-12-01

Variant appearance in text: PTEN: K289E

PubMed Link: 26362251

Variant Present in the following documents:

• Main text

View BVdb publication page

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Opening the conformation is a master switch for the dual localization and phosphatase activity of PTEN.

Scientific Reports

Nguyen, Hoai-Nghia HN; Yang, Jr-Ming JM; Miyamoto, Takafumi T; Itoh, Kie K; Rho, Elmer E; Zhang, Qiang Q; Inoue, Takanari T; Devreotes, Peter N PN; Sesaki, Hiromi H; Iijima, Miho M

Publication Date: 2015-07-28

Variant appearance in text: PTEN: K289E

PubMed Link: 26216063

Variant Present in the following documents:

• Main text

View BVdb publication page

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GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics

Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J

Publication Date: 2015-07-25

Variant appearance in text: PTEN: K289E

PubMed Link: 26206375

Variant Present in the following documents:

• 12859_2015_673_MOESM1_ESM.xls, sheet 1

View BVdb publication page

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Protein monoubiquitylation: targets and diverse functions.

Genes To Cells : Devoted To Molecular & Cellular Mechanisms

Nakagawa, Tadashi T; Nakayama, Keiko K

Publication Date: 2015-07

Variant appearance in text: PTEN: K289E

PubMed Link: 26085183

Variant Present in the following documents:

• Main text

View BVdb publication page

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Neural transcriptome of constitutional Pten dysfunction in mice and its relevance to human idiopathic autism spectrum disorder.

Molecular Psychiatry

Tilot, A K AK; Bebek, G G; Niazi, F F; Altemus, J B JB; Romigh, T T; Frazier, T W TW; Eng, C C

Publication Date: 2016-01

Variant appearance in text: PTEN: K289E

PubMed Link: 25754085

Variant Present in the following documents:

• Main text

View BVdb publication page

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Functionally distinct groups of inherited PTEN mutations in autism and tumour syndromes.

Journal Of Medical Genetics

Spinelli, Laura L; Black, Fiona M FM; Berg, Jonathan N JN; Eickholt, Britta J BJ; Leslie, Nicholas R NR

Publication Date: 2015-02

Variant appearance in text: PTEN: K289E

PubMed Link: 25527629

Variant Present in the following documents:

• jmedgenet-2014-102803-s1.pdf

View BVdb publication page

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Study of PTEN subcellular localization.

Methods (San Diego, Calif.)

Bononi, Angela A; Pinton, Paolo P

Publication Date: 2015-05

Variant appearance in text: PTEN: K289E

PubMed Link: 25312582

Variant Present in the following documents:

• Main text

View BVdb publication page

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Subcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disorders.

Frontiers In Molecular Neuroscience

Kreis, Patricia P; Leondaritis, George G; Lieberam, Ivo I; Eickholt, Britta J BJ

Publication Date: 2014

Variant appearance in text: PTEN: K289E

PubMed Link: 24744697

Variant Present in the following documents:

• Main text
• fnmol-07-00023.pdf

View BVdb publication page

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Germline disruption of Pten localization causes enhanced sex-dependent social motivation and increased glial production.

Human Molecular Genetics

Tilot, Amanda K AK; Gaugler, Mary K MK; Yu, Qi Q; Romigh, Todd T; Yu, Wanfeng W; Miller, Robert H RH; Frazier, Thomas W TW; Eng, Charis C

Publication Date: 2014-06-15

Variant appearance in text: PTEN: K289E

PubMed Link: 24470394

Variant Present in the following documents:

• Main text

View BVdb publication page

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Nuclear PTEN controls DNA repair and sensitivity to genotoxic stress.

Science (New York, N.Y.)

Bassi, C C; Ho, J J; Srikumar, T T; Dowling, R J O RJ; Gorrini, C C; Miller, S J SJ; Mak, T W TW; Neel, B G BG; Raught, B B; Stambolic, V V

Publication Date: 2013-07-26

Variant appearance in text: PTEN: K289E

PubMed Link: 23888040

Variant Present in the following documents:

• Main text

View BVdb publication page

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Synthetic lethal targeting of PTEN-deficient cancer cells using selective disruption of polynucleotide kinase/phosphatase.

Molecular Cancer Therapeutics

Mereniuk, Todd R TR; El Gendy, Mohamed A M MA; Mendes-Pereira, Ana M AM; Lord, Christopher J CJ; Ghosh, Sunita S; Foley, Edan E; Ashworth, Alan A; Weinfeld, Michael M

Publication Date: 2013-10

Variant appearance in text: PTEN: K289E

PubMed Link: 23883586

Variant Present in the following documents:

• Main text

View BVdb publication page

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The Role of PTEN in β-Cell Growth.

The Open Endocrinology Journal

Zeng, Ni N; Bayan, Jennifer-Ann JA; He, Lina L; Stiles, Bangyan B

Publication Date: 2010

Variant appearance in text: PTEN: K289E

PubMed Link: 23853672

Variant Present in the following documents:

• Main text

View BVdb publication page

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Critical role of increased PTEN nuclear translocation in excitotoxic and ischemic neuronal injuries.

The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience

Zhang, Shu S; Taghibiglou, Changiz C; Girling, Kimberly K; Dong, Zhifang Z; Lin, Shinn-Zong SZ; Lee, Wei W; Shyu, Woei-cherng WC; Wang, Yu Tian YT

Publication Date: 2013-05-01

Variant appearance in text: PTEN: K289E

PubMed Link: 23637190

Variant Present in the following documents:

• Main text

View BVdb publication page

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Three-dimensional nuclear telomere architecture changes during endometrial carcinoma development.

Genes, Chromosomes & Cancer

Danescu, Adrian A; Herrero Gonzalez, Sandra S; Di Cristofano, Antonio A; Mai, Sabine S; Hombach-Klonisch, Sabine S

Publication Date: 2013-08

Variant appearance in text: PTEN: K289E

PubMed Link: 23630056

Variant Present in the following documents:

• Main text

View BVdb publication page

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PNUTS functions as a proto-oncogene by sequestering PTEN.

Cancer Research

Kavela, Sridhar S; Shinde, Swapnil R SR; Ratheesh, Raman R; Viswakalyan, Kotapalli K; Bashyam, Murali D MD; Gowrishankar, Swarnalata S; Vamsy, Mohana M; Pattnaik, Sujit S; Rao, Subramanyeshwar S; Sastry, Regulagadda A RA; Srinivasulu, Mukta M; Chen, Junjie J; Maddika, Subbareddy S

Publication Date: 2013-01-01

Variant appearance in text: PTEN: K289E

PubMed Link: 23117887

Variant Present in the following documents:

• Main text

View BVdb publication page

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Ubiquitylation in immune disorders and cancer: from molecular mechanisms to therapeutic implications.

Embo Molecular Medicine

Fulda, Simone S; Rajalingam, Krishnaraj K; Dikic, Ivan I

Publication Date: 2012-07

Variant appearance in text: PTEN: K289E

PubMed Link: 22730341

Variant Present in the following documents:

• Main text

View BVdb publication page

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Regulation of T cell homeostasis and responses by pten.

Frontiers In Immunology

Newton, Ryan H RH; Turka, Laurence A LA

Publication Date: 2012

Variant appearance in text: PTEN: K289E

PubMed Link: 22715338

Variant Present in the following documents:

• Main text

View BVdb publication page

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Thioredoxin and thioredoxin target proteins: from molecular mechanisms to functional significance.

Antioxidants & Redox Signaling

Lee, Samuel S; Kim, Soo Min SM; Lee, Richard T RT

Publication Date: 2013-04-01

Variant appearance in text: PTEN: K289E

PubMed Link: 22607099

Variant Present in the following documents:

• Main text

View BVdb publication page

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Regulation of the nucleocytoplasmic trafficking of viral and cellular proteins by ubiquitin and small ubiquitin-related modifiers.

Biology Of The Cell

Wang, Yao E YE; Pernet, Olivier O; Lee, Benhur B

Publication Date: 2012-03

Variant appearance in text: PTEN: K289E

PubMed Link: 22188262

Variant Present in the following documents:

• Main text

View BVdb publication page

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Characterization of a novel PTEN mutation in MDA-MB-453 breast carcinoma cell line.

Bmc Cancer

Singh, Gobind G; Odriozola, Leticia L; Guan, Hong H; Kennedy, Colin R CR; Chan, Andrew M AM

Publication Date: 2011-11-21

Variant appearance in text: PTEN: K289E

PubMed Link: 22103913

Variant Present in the following documents:

• Main text
• 1471-2407-11-490.pdf

View BVdb publication page

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Naturally occurring germline and tumor-associated mutations within the ATP-binding motifs of PTEN lead to oxidative damage of DNA associated with decreased nuclear p53.

Human Molecular Genetics

He, Xin X; Ni, Ying Y; Wang, Yu Y; Romigh, Todd T; Eng, Charis C

Publication Date: 2011-01-01

Variant appearance in text: PTEN: K289E

PubMed Link: 20926450

Variant Present in the following documents:

• Main text
• ddq434.pdf

View BVdb publication page

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Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors.

Embo Molecular Medicine

Mendes-Pereira, Ana M AM; Martin, Sarah A SA; Brough, Rachel R; McCarthy, Afshan A; Taylor, Jessica R JR; Kim, Jung-Sik JS; Waldman, Todd T; Lord, Christopher J CJ; Ashworth, Alan A

Publication Date: 2009-09

Variant appearance in text: PTEN: K289E

PubMed Link: 20049735

Variant Present in the following documents:

• Main text
• emmm0001-0315.pdf

View BVdb publication page

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Phosphatase and tensin homologue deleted on chromosome 10: extending its PTENtacles.

The International Journal Of Biochemistry & Cell Biology

Stiles, Bangyan L BL

Publication Date: 2009-04

Variant appearance in text: PTEN: K289E

PubMed Link: 18950730

Variant Present in the following documents:

• Main text

View BVdb publication page

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PTEN and the PI3-kinase pathway in cancer.

Annual Review Of Pathology

Chalhoub, Nader N; Baker, Suzanne J SJ

Publication Date: 2009

Variant appearance in text: PTEN: K289E

PubMed Link: 18767981

Variant Present in the following documents:

• Main text

View BVdb publication page

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The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network.

Nature

Song, Min Sup MS; Salmena, Leonardo L; Carracedo, Arkaitz A; Egia, Ainara A; Lo-Coco, Francesco F; Teruya-Feldstein, Julie J; Pandolfi, Pier Paolo PP

Publication Date: 2008-10-09

Variant appearance in text: PTEN: K289E

PubMed Link: 18716620

Variant Present in the following documents:

• Main text

View BVdb publication page

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Ubiquitination regulates PTEN nuclear import and tumor suppression.

Cell

Trotman, Lloyd C LC; Wang, Xinjiang X; Alimonti, Andrea A; Chen, Zhenbang Z; Teruya-Feldstein, Julie J; Yang, Haijuan H; Pavletich, Nikola P NP; Carver, Brett S BS; Cordon-Cardo, Carlos C; Erdjument-Bromage, Hediye H; Tempst, Paul P; Chi, Sung-Gil SG; Kim, Hyo-Jong HJ; Misteli, Tom T; Jiang, Xuejun X; Pandolfi, Pier Paolo PP

Publication Date: 2007-01-12

Variant appearance in text: PTEN: K289E

PubMed Link: 17218261

Variant Present in the following documents:

• Main text

View BVdb publication page

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Protean PTEN: form and function.

American Journal Of Human Genetics

Waite, Kristin A KA; Eng, Charis C

Publication Date: 2002-04

Variant appearance in text: PTEN: K289E

PubMed Link: 11875759

Variant Present in the following documents:

• Main text

View BVdb publication page

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