PTEN c.1007A>T ;(p.Y336F)

Variant ID: 10-89720856-A-T

NM_000314.4(PTEN):c.1007A>T;(p.Y336F)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Mechanism of PRL2 phosphatase-mediated PTEN degradation and tumorigenesis.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Li, Qinglin Q; Bai, Yunpeng Y; Lyle, L Tiffany LT; Yu, Guimei G; Amarasinghe, Ovini O; Nguele Meke, Frederick F; Carlock, Colin C; Zhang, Zhong-Yin ZY
Publication Date: 2020-08-25

Variant appearance in text: PTEN: Y336F
PubMed Link: 32788364
Variant Present in the following documents:
  • Main text
View BVdb publication page



Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research
Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C
Publication Date: 2011-09-01

Variant appearance in text: PTEN: Y336F
PubMed Link: 21727090
Variant Present in the following documents:
  • supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1
View BVdb publication page



Rak functions as a tumor suppressor by regulating PTEN protein stability and function.

Cancer Cell
Yim, Eun-Kyoung EK; Peng, Guang G; Dai, Hui H; Hu, Ruozhen R; Li, Kaiyi K; Lu, Yiling Y; Mills, Gordon B GB; Meric-Bernstam, Funda F; Hennessy, Bryan T BT; Craven, Rolf J RJ; Lin, Shiaw-Yih SY
Publication Date: 2009-04-07

Variant appearance in text: PTEN: Y336F
PubMed Link: 19345329
Variant Present in the following documents:
  • Main text
View BVdb publication page