Genetic Factors for Coronary Heart Disease and Their Mechanisms: A Meta-Analysis and Comprehensive Review of Common Variants from Genome-Wide Association Studies.
Diagnostics (Basel, Switzerland)
Zarkasi, Khairul Anwar KA; Abdullah, Noraidatulakma N; Abdul Murad, Nor Azian NA; Ahmad, Norfazilah N; Jamal, Rahman R
Cardiovascular risk factor mediation of the effects of education and Genetic Risk Score on cardiovascular disease: a prospective observational cohort study of the Framingham Heart Study.
Bmj Open
Powell, Katie L KL; Stephens, Sebastien R SR; Stephens, Alexandre S AS
Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation.
Nature Genetics
Gamazon, Eric R ER; Segrè, Ayellet V AV; van de Bunt, Martijn M; Wen, Xiaoquan X; Xi, Hualin S HS; Hormozdiari, Farhad F; Ongen, Halit H; Konkashbaev, Anuar A; Derks, Eske M EM; Aguet, François F; Quan, Jie J; , ; Nicolae, Dan L DL; Eskin, Eleazar E; Kellis, Manolis M; Getz, Gad G; McCarthy, Mark I MI; Dermitzakis, Emmanouil T ET; Cox, Nancy J NJ; Ardlie, Kristin G KG
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics.
Nature Communications
Barbeira, Alvaro N AN; Dickinson, Scott P SP; Bonazzola, Rodrigo R; Zheng, Jiamao J; Wheeler, Heather E HE; Torres, Jason M JM; Torstenson, Eric S ES; Shah, Kaanan P KP; Garcia, Tzintzuni T; Edwards, Todd L TL; Stahl, Eli A EA; Huckins, Laura M LM; , ; Nicolae, Dan L DL; Cox, Nancy J NJ; Im, Hae Kyung HK
Novel risk genes identified in a genome-wide association study for coronary artery disease in patients with type 1 diabetes.
Cardiovascular Diabetology
Charmet, Romain R; Duffy, Seamus S; Keshavarzi, Sareh S; Gyorgy, Beata B; Marre, Michel M; Rossing, Peter P; McKnight, Amy Jayne AJ; Maxwell, Alexander P AP; Ahluwalia, Tarun Veer Singh TVS; Paterson, Andrew D AD; Trégouët, David-Alexandre DA; Hadjadj, Samy S
Bioinformatic Analysis of Coronary Disease Associated SNPs and Genes to Identify Proteins Potentially Involved in the Pathogenesis of Atherosclerosis.
Journal Of Proteomics And Genomics Research
Mao, Chunhong C; Howard, Timothy D TD; Sullivan, Dan D; Fu, Zongming Z; Yu, Guoqiang G; Parker, Sarah J SJ; Will, Rebecca R; Vander Heide, Richard S RS; Wang, Yue Y; Hixson, James J; Van Eyk, Jennifer J; Herrington, David M DM
Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies.
Genome Biology
Joehanes, Roby R; Zhang, Xiaoling X; Huan, Tianxiao T; Yao, Chen C; Ying, Sai-Xia SX; Nguyen, Quang Tri QT; Demirkale, Cumhur Yusuf CY; Feolo, Michael L ML; Sharopova, Nataliya R NR; Sturcke, Anne A; Schäffer, Alejandro A AA; Heard-Costa, Nancy N; Chen, Han H; Liu, Po-Ching PC; Wang, Richard R; Woodhouse, Kimberly A KA; Tanriverdi, Kahraman K; Freedman, Jane E JE; Raghavachari, Nalini N; Dupuis, Josée J; Johnson, Andrew D AD; O'Donnell, Christopher J CJ; Levy, Daniel D; Munson, Peter J PJ
Coronary Artery Calcification and Rheumatoid Arthritis: Lack of Relationship to Risk Alleles for Coronary Artery Disease in the General Population.
Arthritis & Rheumatology (Hoboken, N.J.)
Ferraz-Amaro, Iván I; Winchester, Robert R; Gregersen, Peter K PK; Reynolds, Richard J RJ; Wasko, Mary Chester MC; Oeser, Anette A; Chung, Cecilia P CP; Stein, C Michael CM; Giles, Jon T JT; Bathon, Joan M JM
Detailed analysis of association between common single nucleotide polymorphisms and subclinical atherosclerosis: The Multi-ethnic Study of Atherosclerosis.
Data In Brief
Vargas, Jose D JD; Manichaikul, Ani A; Wang, Xin-Qun XQ; Rich, Stephen S SS; Rotter, Jerome I JI; Post, Wendy S WS; Polak, Joseph F JF; Budoff, Matthew J MJ; Bluemke, David A DA
Prospective associations of coronary heart disease loci in African Americans using the MetaboChip: the PAGE study.
Plos One
Franceschini, Nora N; Hu, Yijuan Y; Reiner, Alex P AP; Buyske, Steven S; Nalls, Mike M; Yanek, Lisa R LR; Li, Yun Y; Hindorff, Lucia A LA; Cole, Shelley A SA; Howard, Barbara V BV; Stafford, Jeanette M JM; Carty, Cara L CL; Sethupathy, Praveen P; Martin, Lisa W LW; Lin, Dan-Yu DY; Johnson, Karen C KC; Becker, Lewis C LC; North, Kari E KE; Dehghan, Abbas A; Bis, Joshua C JC; Liu, Yongmei Y; Greenland, Philip P; Manson, JoAnn E JE; Maeda, Nobuyo N; Garcia, Melissa M; Harris, Tamara B TB; Becker, Diane M DM; O'Donnell, Christopher C; Heiss, Gerardo G; Kooperberg, Charles C; Boerwinkle, Eric E
Integromic analysis of genetic variation and gene expression identifies networks for cardiovascular disease phenotypes.
Circulation
Yao, Chen C; Chen, Brian H BH; Joehanes, Roby R; Otlu, Burcak B; Zhang, Xiaoling X; Liu, Chunyu C; Huan, Tianxiao T; Tastan, Oznur O; Cupples, L Adrienne LA; Meigs, James B JB; Fox, Caroline S CS; Freedman, Jane E JE; Courchesne, Paul P; O'Donnell, Christopher J CJ; Munson, Peter J PJ; Keles, Sunduz S; Levy, Daniel D
Association of common genetic variants with lipid traits in the Indian population.
Plos One
Walia, Gagandeep Kaur GK; Gupta, Vipin V; Aggarwal, Aastha A; Asghar, Mohammad M; Dudbridge, Frank F; Timpson, Nicholas N; Singh, Nongmaithem Suraj NS; Kumar, M Ravi MR; Kinra, Sanjay S; Prabhakaran, Dorairaj D; Reddy, K Srinath KS; Chandak, Giriraj Ratan GR; Smith, George Davey GD; Ebrahim, Shah S
Heritability and genomics of gene expression in peripheral blood.
Nature Genetics
Wright, Fred A FA; Sullivan, Patrick F PF; Brooks, Andrew I AI; Zou, Fei F; Sun, Wei W; Xia, Kai K; Madar, Vered V; Jansen, Rick R; Chung, Wonil W; Zhou, Yi-Hui YH; Abdellaoui, Abdel A; Batista, Sandra S; Butler, Casey C; Chen, Guanhua G; Chen, Ting-Huei TH; D'Ambrosio, David D; Gallins, Paul P; Ha, Min Jin MJ; Hottenga, Jouke Jan JJ; Huang, Shunping S; Kattenberg, Mathijs M; Kochar, Jaspreet J; Middeldorp, Christel M CM; Qu, Ani A; Shabalin, Andrey A; Tischfield, Jay J; Todd, Laura L; Tzeng, Jung-Ying JY; van Grootheest, Gerard G; Vink, Jacqueline M JM; Wang, Qi Q; Wang, Wei W; Wang, Weibo W; Willemsen, Gonneke G; Smit, Johannes H JH; de Geus, Eco J EJ; Yin, Zhaoyu Z; Penninx, Brenda W J H BW; Boomsma, Dorret I DI
Single nucleotide polymorphisms within LIPA (Lysosomal Acid Lipase A) gene are associated with susceptibility to premature coronary artery disease. a replication in the genetic of atherosclerotic disease (GEA) Mexican study.
Plos One
Vargas-Alarcón, Gilberto G; Posadas-Romero, Carlos C; Villarreal-Molina, Teresa T; Alvarez-León, Edith E; Angeles, Javier J; Vallejo, Maite M; Posadas-Sánchez, Rosalinda R; Cardoso, Guillermo G; Medina-Urrutia, Aida A; Kimura-Hayama, Eric E
Large-scale association analysis identifies new risk loci for coronary artery disease.
Nature Genetics
, ; Deloukas, Panos P; Kanoni, Stavroula S; Willenborg, Christina C; Farrall, Martin M; Assimes, Themistocles L TL; Thompson, John R JR; Ingelsson, Erik E; Saleheen, Danish D; Erdmann, Jeanette J; Goldstein, Benjamin A BA; Stirrups, Kathleen K; König, Inke R IR; Cazier, Jean-Baptiste JB; Johansson, Asa A; Hall, Alistair S AS; Lee, Jong-Young JY; Willer, Cristen J CJ; Chambers, John C JC; Esko, Tõnu T; Folkersen, Lasse L; Goel, Anuj A; Grundberg, Elin E; Havulinna, Aki S AS; Ho, Weang K WK; Hopewell, Jemma C JC; Eriksson, Niclas N; Kleber, Marcus E ME; Kristiansson, Kati K; Lundmark, Per P; Lyytikäinen, Leo-Pekka LP; Rafelt, Suzanne S; Shungin, Dmitry D; Strawbridge, Rona J RJ; Thorleifsson, Gudmar G; Tikkanen, Emmi E; Van Zuydam, Natalie N; Voight, Benjamin F BF; Waite, Lindsay L LL; Zhang, Weihua W; Ziegler, Andreas A; Absher, Devin D; Altshuler, David D; Balmforth, Anthony J AJ; Barroso, Inês I; Braund, Peter S PS; Burgdorf, Christof C; Claudi-Boehm, Simone S; Cox, David D; Dimitriou, Maria M; Do, Ron R; , ; , ; Doney, Alex S F AS; El Mokhtari, NourEddine N; Eriksson, Per P; Fischer, Krista K; Fontanillas, Pierre P; Franco-Cereceda, Anders A; Gigante, Bruna B; Groop, Leif L; Gustafsson, Stefan S; Hager, Jörg J; Hallmans, Göran G; Han, Bok-Ghee BG; Hunt, Sarah E SE; Kang, Hyun M HM; Illig, Thomas T; Kessler, Thorsten T; Knowles, Joshua W JW; Kolovou, Genovefa G; Kuusisto, Johanna J; Langenberg, Claudia C; Langford, Cordelia C; Leander, Karin K; Lokki, Marja-Liisa ML; Lundmark, Anders A; McCarthy, Mark I MI; Meisinger, Christa C; Melander, Olle O; Mihailov, Evelin E; Maouche, Seraya S; Morris, Andrew D AD; Müller-Nurasyid, Martina M; , ; Nikus, Kjell K; Peden, John F JF; Rayner, N William NW; Rasheed, Asif A; Rosinger, Silke S; Rubin, Diana D; Rumpf, Moritz P MP; Schäfer, Arne A; Sivananthan, Mohan M; Song, Ci C; Stewart, Alexandre F R AF; Tan, Sian-Tsung ST; Thorgeirsson, Gudmundur G; van der Schoot, C Ellen CE; Wagner, Peter J PJ; , ; Wells, George A GA; Wild, Philipp S PS; Yang, Tsun-Po TP; Amouyel, Philippe P; Arveiler, Dominique D; Basart, Hanneke H; Boehnke, Michael M; Boerwinkle, Eric E; Brambilla, Paolo P; Cambien, Francois F; Cupples, Adrienne L AL; de Faire, Ulf U; Dehghan, Abbas A; Diemert, Patrick P; Epstein, Stephen E SE; Evans, Alun A; Ferrario, Marco M MM; Ferrières, Jean J; Gauguier, Dominique D; Go, Alan S AS; Goodall, Alison H AH; Gudnason, Villi V; Hazen, Stanley L SL; Holm, Hilma H; Iribarren, Carlos C; Jang, Yangsoo Y; Kähönen, Mika M; Kee, Frank F; Kim, Hyo-Soo HS; Klopp, Norman N; Koenig, Wolfgang W; Kratzer, Wolfgang W; Kuulasmaa, Kari K; Laakso, Markku M; Laaksonen, Reijo R; Lee, Ji-Young JY; Lind, Lars L; Ouwehand, Willem H WH; Parish, Sarah S; Park, Jeong E JE; Pedersen, Nancy L NL; Peters, Annette A; Quertermous, Thomas T; Rader, Daniel J DJ; Salomaa, Veikko V; Schadt, Eric E; Shah, Svati H SH; Sinisalo, Juha J; Stark, Klaus K; Stefansson, Kari K; Trégouët, David-Alexandre DA; Virtamo, Jarmo J; Wallentin, Lars L; Wareham, Nicholas N; Zimmermann, Martina E ME; Nieminen, Markku S MS; Hengstenberg, Christian C; Sandhu, Manjinder S MS; Pastinen, Tomi T; Syvänen, Ann-Christine AC; Hovingh, G Kees GK; Dedoussis, George G; Franks, Paul W PW; Lehtimäki, Terho T; Metspalu, Andres A; Zalloua, Pierre A PA; Siegbahn, Agneta A; Schreiber, Stefan S; Ripatti, Samuli S; Blankenberg, Stefan S SS; Perola, Markus M; Clarke, Robert R; Boehm, Bernhard O BO; O'Donnell, Christopher C; Reilly, Muredach P MP; März, Winfried W; Collins, Rory R; Kathiresan, Sekar S; Hamsten, Anders A; Kooner, Jaspal S JS; Thorsteinsdottir, Unnur U; Danesh, John J; Palmer, Colin N A CN; Roberts, Robert R; Watkins, Hugh H; Schunkert, Heribert H; Samani, Nilesh J NJ
Association of cardiovascular and metabolic disease genes with psoriasis.
The Journal Of Investigative Dermatology
Lu, Yingchang Y; Chen, Haoyan H; Nikamo, Pernilla P; Qi Low, Hui H; Helms, Cynthia C; Seielstad, Mark M; Liu, Jianjun J; Bowcock, Anne M AM; Stahle, Mona M; Liao, Wilson W
A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease.
Circulation. Cardiovascular Genetics
Wild, Philipp S PS; Zeller, Tanja T; Schillert, Arne A; Szymczak, Silke S; Sinning, Christoph R CR; Deiseroth, Arne A; Schnabel, Renate B RB; Lubos, Edith E; Keller, Till T; Eleftheriadis, Medea S MS; Bickel, Christoph C; Rupprecht, Hans J HJ; Wilde, Sandra S; Rossmann, Heidi H; Diemert, Patrick P; Cupples, L Adrienne LA; Perret, Claire C; Erdmann, Jeanette J; Stark, Klaus K; Kleber, Marcus E ME; Epstein, Stephen E SE; Voight, Benjamin F BF; Kuulasmaa, Kari K; Li, Mingyao M; Schäfer, Arne S AS; Klopp, Norman N; Braund, Peter S PS; Sager, Hendrik B HB; Demissie, Serkalem S; Proust, Carole C; König, Inke R IR; Wichmann, Heinz-Erich HE; Reinhard, Wibke W; Hoffmann, Michael M MM; Virtamo, Jarmo J; Burnett, Mary Susan MS; Siscovick, David D; Wiklund, Per Gunnar PG; Qu, Liming L; El Mokthari, Nour Eddine NE; Thompson, John R JR; Peters, Annette A; Smith, Albert V AV; Yon, Emmanuelle E; Baumert, Jens J; Hengstenberg, Christian C; März, Winfried W; Amouyel, Philippe P; Devaney, Joseph J; Schwartz, Stephen M SM; Saarela, Olli O; Mehta, Nehal N NN; Rubin, Diana D; Silander, Kaisa K; Hall, Alistair S AS; Ferrieres, Jean J; Harris, Tamara B TB; Melander, Olle O; Kee, Frank F; Hakonarson, Hakon H; Schrezenmeir, Juergen J; Gudnason, Vilmundur V; Elosua, Roberto R; Arveiler, Dominique D; Evans, Alun A; Rader, Daniel J DJ; Illig, Thomas T; Schreiber, Stefan S; Bis, Joshua C JC; Altshuler, David D; Kavousi, Maryam M; Witteman, Jaqueline C M JC; Uitterlinden, Andre G AG; Hofman, Albert A; Folsom, Aaron R AR; Barbalic, Maja M; Boerwinkle, Eric E; Kathiresan, Sekar S; Reilly, Muredach P MP; O'Donnell, Christopher J CJ; Samani, Nilesh J NJ; Schunkert, Heribert H; Cambien, Francois F; Lackner, Karl J KJ; Tiret, Laurence L; Salomaa, Veikko V; Munzel, Thomas T; Ziegler, Andreas A; Blankenberg, Stefan S