Publications:

CYP2C9 and CYP2C19: Deep Mutational Scanning and Functional Characterization of Genomic Missense Variants.

Clinical And Translational Science

Zhang, Lingxin L; Sarangi, Vivekananda V; Moon, Irene I; Yu, Jia J; Liu, Duan D; Devarajan, Sandhya S; Reid, Joel M JM; Kalari, Krishna R KR; Wang, Liewei L; Weinshilboum, Richard R

Publication Date: 2020-07

Variant appearance in text: CYP2C19: 65A>G; Q22R; rs144928727

PubMed Link: 32004414

Variant Present in the following documents:

• Main text
• CTS-13-727.pdf

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Pharmacogenomic Next-Generation DNA Sequencing: Lessons from the Identification and Functional Characterization of Variants of Unknown Significance in CYP2C9 and CYP2C19.

Drug Metabolism And Disposition: The Biological Fate Of Chemicals

Devarajan, Sandhya S; Moon, Irene I; Ho, Ming-Fen MF; Larson, Nicholas B NB; Neavin, Drew R DR; Moyer, Ann M AM; Black, John L JL; Bielinski, Suzette J SJ; Scherer, Steven E SE; Wang, Liewei L; Weinshilboum, Richard M RM; Reid, Joel M JM

Publication Date: 2019-04

Variant appearance in text: CYP2C19: Gln22Arg; rs144928727

PubMed Link: 30745309

Variant Present in the following documents:

• Main text

View BVdb publication page

Interindividual variability of CYP2C19-catalyzed drug metabolism due to differences in gene diplotypes and cytochrome P450 oxidoreductase content.

The Pharmacogenomics Journal

Shirasaka, Y Y; Chaudhry, A S AS; McDonald, M M; Prasad, B B; Wong, T T; Calamia, J C JC; Fohner, A A; Thornton, T A TA; Isoherranen, N N; Unadkat, J D JD; Rettie, A E AE; Schuetz, E G EG; Thummel, K E KE

Publication Date: 2016-08

Variant appearance in text: CYP2C19: Q22R; rs144928727

PubMed Link: 26323597

Variant Present in the following documents:

• Main text
• tpj201558a.pdf
• tpj201558x3.pdf
• tpj201558x2.pdf

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