Publications:

Comprehensive in vitro and in silico assessments of metabolic capabilities of 24 genomic variants of CYP2C19 using two different substrates.

Frontiers In Pharmacology

Seo, Myung-Eui ME; Min, Byung-Joo BJ; Heo, Nayoon N; Lee, Kye Hwa KH; Kim, Ju Han JH

Publication Date: 2023

Variant appearance in text: CYP2C19: 556C>T; Arg186Cys; rs183701923

PubMed Link: 36713839

Variant Present in the following documents:

• Main text
• fphar-14-1055991.pdf

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The genetic landscape of major drug metabolizing cytochrome P450 genes-an updated analysis of population-scale sequencing data.

The Pharmacogenomics Journal

Zhou, Yitian Y; Lauschke, Volker M VM

Publication Date: 2022-12

Variant appearance in text: CYP2C19: 556C>T; Arg186Cys; rs183701923

PubMed Link: 36068297

Variant Present in the following documents:

• 41397_2022_288_MOESM4_ESM.xlsx, sheet 1

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The Extent and Impact of Variation in ADME Genes in Sub-Saharan African Populations.

Frontiers In Pharmacology

da Rocha, Jorge E B JEB; Othman, Houcemeddine H; Botha, Gerrit G; Cottino, Laura L; Twesigomwe, David D; Ahmed, Samah S; Drögemöller, Britt I BI; Fadlelmola, Faisal M FM; Machanick, Philip P; Mbiyavanga, Mamana M; Panji, Sumir S; Wright, Galen E B GEB; Adebamowo, Clement C; Matshaba, Mogomotsi M; Ramsay, Michéle M; Simo, Gustave G; Simuunza, Martin C MC; Tiemessen, Caroline T CT; Baldwin, Sandra S; Chiano, Mathias M; Cox, Charles C; Gross, Annette S AS; Thomas, Pamela P; Gamo, Francisco-Javier FJ; Hazelhurst, Scott S

Publication Date: 2021

Variant appearance in text: rs183701923

PubMed Link: 34721006

Variant Present in the following documents:

• datasheet1.pdf

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CYP2C9 and CYP2C19: Deep Mutational Scanning and Functional Characterization of Genomic Missense Variants.

Clinical And Translational Science

Zhang, Lingxin L; Sarangi, Vivekananda V; Moon, Irene I; Yu, Jia J; Liu, Duan D; Devarajan, Sandhya S; Reid, Joel M JM; Kalari, Krishna R KR; Wang, Liewei L; Weinshilboum, Richard R

Publication Date: 2020-07

Variant appearance in text: CYP2C19: 556C>T; Arg186Cys; rs183701923

PubMed Link: 32004414

Variant Present in the following documents:

• Main text
• CTS-13-727.pdf

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Pharmacogenomic Next-Generation DNA Sequencing: Lessons from the Identification and Functional Characterization of Variants of Unknown Significance in CYP2C9 and CYP2C19.

Drug Metabolism And Disposition: The Biological Fate Of Chemicals

Devarajan, Sandhya S; Moon, Irene I; Ho, Ming-Fen MF; Larson, Nicholas B NB; Neavin, Drew R DR; Moyer, Ann M AM; Black, John L JL; Bielinski, Suzette J SJ; Scherer, Steven E SE; Wang, Liewei L; Weinshilboum, Richard M RM; Reid, Joel M JM

Publication Date: 2019-04

Variant appearance in text: CYP2C19: Arg186Cys; rs183701923

PubMed Link: 30745309

Variant Present in the following documents:

• Main text

View BVdb publication page