CYP2C19 c.1034T>A ;(p.M345K)

Variant ID: 10-96602666-T-A

NM_000769.1(CYP2C19):c.1034T>A;(p.M345K)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Comprehensive in vitro and in silico assessments of metabolic capabilities of 24 genomic variants of CYP2C19 using two different substrates.

Frontiers In Pharmacology
Seo, Myung-Eui ME; Min, Byung-Joo BJ; Heo, Nayoon N; Lee, Kye Hwa KH; Kim, Ju Han JH
Publication Date: 2023

Variant appearance in text: CYP2C19: 1034T>A; Met345Lys; rs201132803
PubMed Link: 36713839
Variant Present in the following documents:
  • Main text
  • fphar-14-1055991.pdf
View BVdb publication page



The genetic landscape of major drug metabolizing cytochrome P450 genes-an updated analysis of population-scale sequencing data.

The Pharmacogenomics Journal
Zhou, Yitian Y; Lauschke, Volker M VM
Publication Date: 2022-12

Variant appearance in text: CYP2C19: 1034T>A; Met345Lys; rs201132803
PubMed Link: 36068297
Variant Present in the following documents:
  • 41397_2022_288_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Identification of pharmacogenetic variants from large scale next generation sequencing data in the Saudi population.

Plos One
Goljan, Ewa E; Abouelhoda, Mohammed M; ElKalioby, Mohamed M MM; Jabaan, Amjad A; Alghithi, Nada N; Meyer, Brian F BF; Monies, Dorota D
Publication Date: 2022

Variant appearance in text: CYP2C19: 1034T>A; Met345Lys; rs201132803
PubMed Link: 35089958
Variant Present in the following documents:
  • pone.0263137.s002.xlsx, sheet 1
View BVdb publication page



CYP2C9 and CYP2C19: Deep Mutational Scanning and Functional Characterization of Genomic Missense Variants.

Clinical And Translational Science
Zhang, Lingxin L; Sarangi, Vivekananda V; Moon, Irene I; Yu, Jia J; Liu, Duan D; Devarajan, Sandhya S; Reid, Joel M JM; Kalari, Krishna R KR; Wang, Liewei L; Weinshilboum, Richard R
Publication Date: 2020-07

Variant appearance in text: CYP2C19: 1034T>A; M345K; rs201132803
PubMed Link: 32004414
Variant Present in the following documents:
  • Main text
  • CTS-13-727.pdf
View BVdb publication page



Genetic variation in human drug-related genes.

Genome Medicine
Schärfe, Charlotta Pauline Irmgard CPI; Tremmel, Roman R; Schwab, Matthias M; Kohlbacher, Oliver O; Marks, Debora Susan DS
Publication Date: 2017-12-22

Variant appearance in text: rs201132803
PubMed Link: 29273096
Variant Present in the following documents:
  • 13073_2017_502_MOESM2_ESM.xlsx, sheet 2
View BVdb publication page